Now showing items 1-10 of 22

    • Angiotensin II chronic infusion induces B1 receptor expression in aorta of rats 

      Ceravolo, Graziela Scalanti; Fernandes, Liliam [UNIFESP]; Munhoz, Carolina Demarchi; Fernandes, Denise de Castro; Tostes, Rita de Cassia Aleixo; Laurindo, Francisco Rafael Martins; Scavone, Cristoforo; Fortes, Zuleica Bruno; Carvalho, Maria Helena Catelli de (Lippincott Williams & Wilkins, 2007-10-01)
      We investigated whether angiotensin II infusion modulates in vivo the kinin B1 receptor expression and the mechanisms involved in this process. We also evaluated the role of the B1 receptor activation in aorta. Wistar rats ...

    • Angiotensin II induces superoxide generation via NAD(P)H oxidase activation in isolated rat pancreatic islets 

      Hirata, A. E. [UNIFESP]; Morgan, D.; Oliveira-Emilio, H. R.; Rocha, M. S.; Carvalho, C. R. O.; Curi, R.; Carpinelli, A. R. (Elsevier B.V., 2009-02-25)
      Angiotensin II (Ang II) controls blood pressure, electrolyte balance, cell growth and vascular remodeling. Ang II activates NAD(P)H oxidase in several tissues with important function in the control of insulin secretion. ...

    • Angiotensin II or epinephrine hemodynamic and metabolic responses in the liver of L-NAME induced hypertension and spontaneous hypertensive rats 

      Kimura, Debora Conte [UNIFESP]; Nagaoka, Márcia Regina [UNIFESP]; Borges, Durval Rosa [UNIFESP]; Kouyoumdjian, Maria [UNIFESP] (Baishideng Publishing Group Inc, 2017)
      AIM To study hepatic vasoconstriction and glucose release induced by angiotensin (Ang)II or Epi in rats with pharmacological hypertension and spontaneously hypertensive rat (SHR). METHODS Isolated liver perfusion was ...

    • Angiotensin II-induced JNK activation is mediated by NAD(P)H oxidase in isolated rat pancreatic islets 

      Alves, Eduardo da Silva [UNIFESP]; Haidar, André Abou [UNIFESP]; Quadros, Caren Dal'Mora de [UNIFESP]; Carvalho, Daniela S. [UNIFESP]; Morgan, Daniela; Rocha, Marlene Santos da; Curi, Rui; Carpinelli, Angelo Rafael; Hirata, Aparecida Emiko [UNIFESP] (Elsevier B.V., 2012-04-10)
      Angiotensin II (All), the active component of the renin angiotensin system (RAS), plays a vital role in the regulation of physiological processes of the cardiovascular system, but also has autocrine and paracrine actions ...

    • Autonomic dysregulation in ob/ob mice is improved by inhibition of angiotensin-converting enzyme 

      Hilzendeger, Aline Mourão [UNIFESP]; Costa Goncalves, Andrey C. da; Plehm, Ralph; Diedrich, Andre; Gross, Volkmar; Pesquero, Joao B. [UNIFESP]; Bader, Michael (Springer, 2010-04-01)
      The leptin-deficient ob/ob mice are insulin resistant and obese. However, the control of blood pressure in this model is not well defined. the goal of this study was to evaluate the role of leptin and of the renin-angiotensin ...

    • Biological and conformational evaluation of angiotensin II lactam bridge containing analogues 

      Oliveira Junior, Vani Xavier; Fázio, Marcos Antonio [UNIFESP]; Silva, Adriana Farias; Campana, Patricia Targon; Pesquero, João Bosco [UNIFESP]; Santos, Edson Lucas; Costa-Neto, Cláudio Miguel; Miranda, Antonio [UNIFESP] (Elsevier B.V., 2011-12-10)
      Angiotensin II (All) is the active octapeptide product of the renin enzymatic cascade, which is responsible for sustaining blood pressure. in an attempt to establish the All-receptor-bound conformation of this octapeptide, ...

    • Cecropia pachystachya extract attenuated the renal lesion in 5/6 nephrectomized rats by reducing inflammation and renal arginase activity 

      Maquiaveli, Claudia C.; Silva, Edson R. da; Rosa, Lara C.; Francescato, Heloisa D. C.; Lucon Junior, Joao Francisco; Silva, Cleonice G. A.; Casarini, Dulce E. [UNIFESP]; Ronchi, Fernanda A. [UNIFESP]; Coimbra, Terezila M. (Elsevier B.V., 2014-12-02)
      Ethnopharmacological relevance: the plant Cecropia pachystachya Trecul has been used in Brazilian folk medicine to treat hypertension, bladder and kidney inflammation and renal diseases. the aim of this study was to evaluate ...

    • Circulating renin-angiotensin system and catecholamines in childhood: is there a role for birthweight? 

      Franco, Maria do Carmo Pinho [UNIFESP]; Casarini, Dulce Elena [UNIFESP]; Carneiro-Ramos, Marcella S.; Sawaya, Ana Lydia [UNIFESP]; Barreto-Chaves, Maria Luiza M.; Sesso, Ricardo de Castro Cintra [UNIFESP] (Portland Press Ltd, 2008-03-01)
      There have been only a few reports on the sympathoadrenal and renin-angiotensin systems in children of small gestational age. the purpose of the present study was to investigate plasma levels of ACE (angiotensin-converting ...

    • Efeitos cardiovasculares e renais da denervação seletiva das fibras sensoriais renais na Hipertensão Renovascular Experimental 

      Lopes, Nathalia Rodrigues [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2019-07-25)
      It is known that oxidative stress and increased renal sympathetic nervous activity (rSNA) play an important role in arterial hypertension (AH). Under physiological conditions, renal sympathetic fibers control renin release, ...

    • Effects of Amino Acid Deletion on the Antiplasmodial Activity of Angiotensin II 

      Rodrigues Ferreira, Luiz Henrique; Silva, Adriana Farias; Torossian Torres, Marcelo Der; Pedron, Cibele Nicolaski; Capurro, Margareth Lara; Alves, Flavio Lopes [UNIFESP]; Miranda, Antonio [UNIFESP]; Oliveira, Vani Xavier (Springer, 2014-12-01)
      Malaria is an infectious disease for which effective treatment and prevention strategies remain limited. Our group recently reported that angiotensin II (AII) presents antiplasmodial activity and inhibits the development ...