Now showing items 1-10 of 19

    • Acute total sleep deprivation potentiates amphetamine-induced locomotor-stimulant effects and behavioral sensitization in mice 

      Saito, Luis P. [UNIFESP]; Fukushiro, Daniela F. [UNIFESP]; Hollais, Andre W. [UNIFESP]; Mari-Kawamoto, Elisa [UNIFESP]; Costa, Jacqueline M. [UNIFESP]; Berro, Lais F. [UNIFESP]; Aramini, Tatiana C. F. [UNIFESP]; Wuo-Silva, Raphael [UNIFESP]; Andersen, Monica L. [UNIFESP]; Tufik, Sergio [UNIFESP]; Frussa-Filho, Roberto [UNIFESP] (Elsevier B.V., 2014-02-01)
      It has been demonstrated that a prolonged period (48 h) of paradoxical sleep deprivation (PSD) potentiates amphetamine (AMP)-induced behavioral sensitization, an animal model of addiction-related neuroadaptations. in the ...

    • Adolescent mice are more vulnerable than adults to single injection-induced behavioral sensitization to amphetamine 

      Kameda, Sonia Regina [UNIFESP]; Fukushiro, Daniela Fukue [UNIFESP]; Trombin, Thaís Fernanda [UNIFESP]; Procopio-Souza, Roberta [UNIFESP]; Patti, Camilla de Lima [UNIFESP]; Hollais, André Willian [UNIFESP]; Calzavara, Mariana Bendlin [UNIFESP]; Abílio, Vanessa Costhek [UNIFESP]; Ribeiro, Rosana de Alencar [UNIFESP]; Tufik, Sergio [UNIFESP]; D'Almeida, Vânia [UNIFESP]; Frussa Filho, Roberto [UNIFESP] (Elsevier B.V., 2011-04-01)
      Drug-induced behavioral sensitization in rodents has enhanced our understanding of why drugs acquire increasing motivational and incentive value. Compared to adults, human adolescents have accelerated dependence courses ...

    • Amphetamine-induced memory impairment in a discriminative avoidance task is state-dependent in mice 

      Sanday, Leandro [UNIFESP]; Patti, Camilla de Lima [UNIFESP]; Zanin, Karina Agustini [UNIFESP]; Tufik, Sergio [UNIFESP]; Frussa-Filho, Roberto [UNIFESP] (Cambridge Univ Press, 2013-04-01)
      In both humans and laboratory animals, the reports of cognitive effects following acute amphetamine (Amph) administration are mixed and depend, for example, on the timing of administration (e. g. before or after task ...

    • Changes of cytosolic calcium and contractility of young rat vas deferens by acute treatment with amphetamine, fluoxetine or sibutramine 

      Jurkiewicz, Neide Hyppolito [UNIFESP]; Silva Junior, Edilson Dantas da [UNIFESP]; Souza, Bruno Palmieri de [UNIFESP]; Verde, Luciana Ferreira [UNIFESP]; Pereira, Janaina Drawanz [UNIFESP]; Sobrinho, Cairo Mendes [UNIFESP]; Smaili, Soraya Soubhi [UNIFESP]; Caricati-Neto, Afonso [UNIFESP]; Miranda-Ferreira, Regiane [UNIFESP]; Jurkiewicz, Aron [UNIFESP] (Elsevier B.V., 2012-09-15)
      Previous studies conducted in our laboratory indicated that administration of amphetamine, fluoxetine or sibutramine affects the sympathetic nervous system of the rat vas deferens. Therefore, our goal was to verify the ...

    • Chronic amphetamine transforms the emotional significance of a novel but not a familiar environment: implications for addiction 

      Fukushiro, Daniela Fukue [UNIFESP]; Frussa Filho, Roberto [UNIFESP] (Cambridge Univ Press, 2011-08-01)
      Both drug-induced locomotor sensitization and reactivity to novelty in rodents have been related to drug-craving mechanisms in humans. We investigated whether the exposure to a completely novel environment would modulate ...

    • Differential effects of intermittent and continuous exposure to novel environmental stimuli on the development of amphetamine-induced behavioral sensitization in mice: Implications for addiction 

      Fukushiro, Daniela F. [UNIFESP]; Josino, Fabiana S. [UNIFESP]; Saito, Luis P. [UNIFESP]; Costa, Jacqueline M. [UNIFESP]; Zanlorenci, Lineane H. F. [UNIFESP]; Berro, Lais F. [UNIFESP]; Fernandes-Santos, Luciano [UNIFESP]; Morgado, Fiorella [UNIFESP]; Mari-Kawamoto, Elisa [UNIFESP]; Frussa-Filho, Roberto [UNIFESP] (Elsevier B.V., 2012-07-01)
      Background: Previous studies have demonstrated a preventive effect of continuous environmental enrichment during early development on the vulnerability of rodents to drug addiction-related behaviors. Recently, it was ...

    • Effects of antipsychotics and amphetamine on social behaviors in spontaneously hypertensive rats 

      Calzavara, Mariana Bendlin [UNIFESP]; Levin, Raquel [UNIFESP]; Medrano, Wladimir Agostini [UNIFESP]; Almeida, Valeria [UNIFESP]; Frois Sampaio, Antonio Pereira [UNIFESP]; Barone, Lucas Cerqueira [UNIFESP]; Frussa-Filho, Roberto [UNIFESP]; Abilio, Vanessa Costhek [UNIFESP] (Elsevier B.V., 2011-11-20)
      We have recently reported that spontaneously hypertensive rats (SHRs) exhibit a deficit in contextual fear conditioning that is specifically reversed by antipsychotic and potentiated by psychostimulants and other manipulations ...

    • Effects of environmental enrichment and paradoxical sleep deprivation on open-field behavior of amphetamine-treated mice 

      Fukushiro, Daniela Fukue [UNIFESP]; Calzavara, Mariana Bendlin [UNIFESP]; Trombin, Thaís Fernanda [UNIFESP]; Lopez, Giorgia Batlle [UNIFESP]; Abilio, Vanessa Costhek [UNIFESP]; Andersen, Monica Levy [UNIFESP]; Tufik, Sergio [UNIFESP]; Frussa-Filho, Roberto [UNIFESP] (Elsevier B.V., 2007-11-23)
      Background: Environmental enrichment or paradoxical sleep deprivation (PSD) has been shown to modify some responses elicited by drugs of abuse. the aims of the present study were to examine the effects of environmental ...

    • The effects of paradoxical sleep deprivation on amphetamine-induced behavioral sensitization in adult and adolescent mice 

      Kameda, Sonia R. [UNIFESP]; Fukushiro, Daniela F. [UNIFESP]; Trombin, Thais F. [UNIFESP]; Sanday, Leandro [UNIFESP]; Wuo-Silva, Raphael [UNIFESP]; Saito, Luis R. [UNIFESP]; Tufik, Sergio [UNIFESP]; D'Almeida, Vania [UNIFESP]; Frussa-Filho, Roberto [UNIFESP] (Elsevier B.V., 2014-08-30)
      Drug-induced behavioral sensitization (BS), paradoxical sleep deprivation (PSD) and adolescence in rodents are associated with changes in the mesolimbic dopaminergic system. We compared the effects of PSD on amphetamine-induced ...

    • Electrophysiological correlates of sleep disturbance induced by acute and chronic administration of D-amphetamine 

      Andersen, Monica L. [UNIFESP]; Margis, Regina; Frey, Benicio N.; Giglio, Larriany M. F.; Kapczinski, Flavio; Tufik, Sergio [UNIFESP] (Elsevier B.V., 2009-01-16)
      Sleep disturbance is the strongest predictor of manic relapse and is considered one of the most important objective measures of treatment response in bipolar disorder (BD). However, the neurobiological mechanisms underlying ...