Now showing items 1-10 of 61

    • Adaptação transcultural da escala de avaliação de incapacidade em demência (Disability Assessment For Dementia - DAD) 

      Carthery-goulart, Maria Tereza; Areza-fegyveres, Renata; Schultz, Rodrigo R. [UNIFESP]; Okamoto, Ivan [UNIFESP]; Caramelli, Paulo; Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Nitrini, Ricardo (Academia Brasileira de Neurologia - ABNEURO, 2007-09-01)
      The original version of the Disability Assessment for Dementia (DAD) was translated into Portuguese and back translated to English. The divergences of translation were identified and discussed, resulting in a version that ...

    • Alterações de linguagem nas fases iniciais da doença de Alzheimer 

      Ortiz, Karin Zazo [UNIFESP]; Bertolucci, Paulo Henrique Ferreira [UNIFESP] (Academia Brasileira de Neurologia - ABNEURO, 2005-06-01)
      Alzheimer disease (AD) is usually associated with cognitive, language and behavioral impairments, which can get more and more serious as the disease progresses. The aim of this study is to verify language disorders in the ...

    • Apolipoprotein A-V gene polymorphism -1131T > C and Alzheimer's disease 

      Barbosa, Fabio Augusto Freiria; Labio, Roger Willian de; Rigolin, Valdeci Oliveira Santos [UNIFESP]; Minett, Thaís Soares Cianciarullo [UNIFESP]; Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Smith, Marilia de Arruda Cardoso [UNIFESP]; Payão, Spencer Luiz Marques [UNIFESP] (Ios Press, 2006-12-01)
      Alzheimer's disease (AD) is the most common neurodegenerative disorder in the elderly and is also considered a progeroid genetic syndrome. The etiology of AD is complex and the mechanisms underlying its pathophysiology ...

    • Apolipoprotein E genotype is not associated with cognitive impairment in older adults with bipolar disorder 

      Kerr, Daniel Shikanai; Stella, Florindo; Radanovic, Marcia; Aprahamian, Ivan; Bertollucci, Paulo Henrique Ferreira [UNIFESP]; Forlenza, Orestes Vicente (Wiley-Blackwell, 2016)
      ObjectivesCognitive decline is part of the long-term outcome for many individuals with bipolar disorder (BD). The epsilon 4 allele (APOE*4) of apolipoprotein E (APOE) is a well-established risk factor for dementia in ...

    • Apolipoprotein E genotype is not associated with cognitive impairment in older adults with bipolar disorder 

      Kerr, Daniel Shikanai; Stella, Florindo; Radanovic, Marcia; Aprahamian, Ivan; Bertollucci, Paulo Henrique Ferreira [UNIFESP]; Forlenza, Orestes Vicente (Wiley-Blackwell, 2016)
      ObjectivesCognitive decline is part of the long-term outcome for many individuals with bipolar disorder (BD). The epsilon 4 allele (APOE*4) of apolipoprotein E (APOE) is a well-established risk factor for dementia in ...

    • Apolipoprotein E4 allele and ribosomal genes in Alzheimer's disease 

      Tavares, W. M.; Speranca, M. A.; Labio, Roger Willian de; Peres, Clovis de Araujo [UNIFESP]; Okamoto, Ivan Hideyo [UNIFESP]; Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Smith, Marilia de Arruda Cardoso [UNIFESP]; Payão, Spencer Luiz Marques [UNIFESP] (Ios Press, 2004-08-01)
      Ribosomal genes are involved in cellular transcription, translation and gene expression modulation process. An association between 28S/18S rRNA ratio levels with apoptosis and aging has been reported. Moulder et al. [22] ...

    • Apoptosis induced by A beta 25-35 peptide is Ca2+-IP3 signaling-dependent in murine astrocytes 

      Oseki, K. T. [UNIFESP]; Monteforte, P. T. [UNIFESP]; Pereira, G. J. S. [UNIFESP]; Hirata, H. [UNIFESP]; Ureshino, R. P. [UNIFESP]; Bincoletto, C. [UNIFESP]; Hsu, Y. -T.; Smaili, Soraya Soubhi [UNIFESP] (Wiley-Blackwell, 2014-08-01)
      Although the accumulation of the neurotoxic peptide beta-amyloid (A beta) in the central nervous system is a hallmark of Alzheimer's disease, whether A beta acts in astrocytes is unclear, and downstream functional consequences ...

    • Are Major Depressive Disorder and Diabetes Mellitus Amyloidogenic Conditions? 

      Baskaran, Anusha; Carvalho, Andre F.; Mansur, Rodrigo Barbachan [UNIFESP]; McIntyre, Roger S. (Bentham Science Publ Ltd, 2014-01-01)
      Major depressive disorder (MDD) and diabetes mellitus (DM) have reciprocal relationship and share common pathophysiological mechanisms in the central nervous system. Depression and diabetes negatively affect cognitive ...

    • Assessment of sleep satisfaction in patients with dementia due to Alzheimer's disease 

      Oliveira, Fabricio Ferreira de [UNIFESP]; Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Chen, Elizabeth Suchi [UNIFESP]; Smith, Marilia de Arruda Cardoso [UNIFESP] (Elsevier B.V., 2014-12-01)
      Sleep length and architecture are potential markers of progressive cognitive impairment, while neuropsychiatric symptoms and APOE4- haplotypes have been associated with more sleep complaints in patients with dementia due ...

    • Association analysis between K and-116A variants of butyrylcholinesterase and Alzheimer's disease in a Brazilian population 

      Simao-Silva, Daiane Priscila; Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Labio, Roger William de; Payão, Spencer Luiz Marques [UNIFESP]; Furtado-Alle, Lupe; Rodrigues Souza, Ricardo Lehtonen (Elsevier B.V., 2013-03-25)
      In Alzheimer's disease (AD) a reduction in acetylcholinesterase (AChE) and an increase in butyrylcholinesterase (BChE) activity are observed. K variant (539T) is the most common variant of the BCHE gene and, although ...