Now showing items 1-5 of 5

    • Acute Kidney Injury Reduces Phagocytic and Microbicidal Capacities of Alveolar Macrophages 

      Silva, Reinaldo Correia [UNIFESP]; Landgraf, Maristella de Almeida [UNIFESP]; Correa-Costa, Matheus; Semedo, Patricia [UNIFESP]; Cenedeze, Marcos Antonio [UNIFESP]; Pacheco-Silva, Alvaro [UNIFESP]; Landgraf, Richardt Gama [UNIFESP]; Câmara, Niels Olsen Saraiva [UNIFESP] (Karger, 2013-01-01)
      Background/Aims: Renal ischaemia-reperfusion injury (IRI) is a systemic inflammatory process in which Th1 responses predominate affecting other organs including the lungs. the present study explored the phagocytic and ...

    • Leukotrienes Produced in Allergic Lung Inflammation Activate Alveolar Macrophages 

      Silva, Reinaldo Correia [UNIFESP]; Landgraf, Maristella de Almeida; Hiyane, Meire Ioshie [UNIFESP]; Pacheco-Silva, Alvaro [UNIFESP]; Camara, Niels Olsen Saraiva [UNIFESP]; Landgraf, Richardt Gama [UNIFESP] (Karger, 2010-01-01)
      It has been well-documented that leukotrienes (LTs) are released in allergic lung inflammation and that they participate in the physiopathology of asthma. A role for LTs in innate immunity has recently emerged: Cys-LTs ...

    • Low-level laser therapy (LLLT) acts as cAMP-elevating agent in acute respiratory distress syndrome 

      Lima, Flavia Mafra de; Moreira, Leonardo M.; Villaverde, A. B.; Albertini, Regiane; Castro-Faria-Neto, Hugo C.; Aimbire, Flavio [UNIFESP] (Springer, 2011-05-01)
      The aim of this work was to investigate if the low-level laser therapy (LLLT) on acute lung inflammation (ALI) induced by lipopolysaccharide (LPS) is linked to tumor necrosis factor (TNF) in alveolar macrophages (AM) from ...

    • Low-level laser therapy suppresses the oxidative stress-induced glucocorticoids resistance in U937 cells: Relevance to cytokine secretion and histone deacetylase in alveolar macrophages 

      Souza, Nadhia Helena Costa; Marcondes, Priscila Toledo [UNIFESP]; Albertini, Regiane; Mesquita Ferrari, Raquel Agnelli; Fernandes, Kristianne Porta Santos; Aimbire, Flavio [UNIFESP] (Elsevier B.V., 2014-01-05)
      Oxidative stress is present in severe asthma and contributes to the low response to corticoids through the downregulation of histone deacetylase (HDAC) and the increase of cytokines. Low-level laser therapy (LLLT) has been ...

    • Protective role of NKT cells and macrophage M2-driven phenotype in bleomycin-induced pulmonary fibrosis 

      Grabarz, Felipe; Aguiar, Cristhiane Favero; Correa-Costa, Matheus; Braga, Tarcio Teodoro; Hyane, Meire Ioshie [UNIFESP]; Andrade-Oliveira, Vinicius; Landgraf, Maristella de Almeida [UNIFESP]; Câmara, Niels Olsen Saraiva [UNIFESP] (Springer Basel Ag, 2018)
      Pulmonary fibrosis is a result of an abnormal wound healing in lung tissue triggered by an excessive accumulation of extracellular matrix proteins, loss of tissue elasticity, and debit of ventilatory function. NKT cells ...