Now showing items 1-10 of 18

    • Adipose Tissue-Derived Stem Cell Treatment Prevents Renal Disease Progression 

      Donizetti-Oliveira, Cassiano [UNIFESP]; Semedo, Patricia [UNIFESP]; Burgos-Silva, Marina [UNIFESP]; Cenedeze, Marco Antonio [UNIFESP]; Malheiros, Denise Maria Avancini Costa; Reis, Marlene A.; Pacheco-Silva, Alvaro [UNIFESP]; Câmara, Niels Olsen Saraiva [UNIFESP] (Cognizant Communication Corp, 2012-01-01)
      Adipose tissue-derived stem cells (ASCs) are an attractive source of stem cells with regenerative properties that are similar to those of bone marrow stem cells. Here, we analyze the role of ASCs in reducing the progression ...

    • Bone marrow mononuclear cells attenuate fibrosis development after severe acute kidney injury 

      Semedo, Patricia [UNIFESP]; Donizetti-Oliveira, Cassiano [UNIFESP]; Burgos-Silva, Marina [UNIFESP]; Cenedeze, Marco Antonio [UNIFESP]; Malheiros, Denise Maria Avancini Costa; Pacheco-Silva, Alvaro [UNIFESP]; Camara, Niels Olsen Saraiva [UNIFESP] (Nature Publishing Group, 2010-05-01)
      One of the early phases that lead to fibrosis progression is inflammation. Once this stage is resolved, fibrosis might be prevented. Bone marrow mononuclear cells (BMMCs) are emerging as a new therapy for several pathologies, ...

    • Endothelin-1 receptor antagonists protect the kidney against the nephrotoxicity induced by cyclosporine-A in normotensive and hypertensive rats 

      Caires, A. [UNIFESP]; Fernandes, G. S. [UNIFESP]; Leme, A. M. [UNIFESP]; Castino, B.; Pessoa, E. A. [UNIFESP]; Fernandes, S. M.; Fonseca, C. D. [UNIFESP]; Vattimo, M. F.; Schor, N. [UNIFESP]; Borges, F. T. [UNIFESP] (Assoc Bras Divulg Cientifica, 2018)
      Cyclosporin-A (CsA) is an immunosuppressant associated with acute kidney injury and chronic kidney disease. Nephrotoxicity associated with CsA involves the increase in afferent and efferent arteriole resistance, decreased ...

    • Essential Elements as Biomarkers of Acute Kidney Injury and Spontaneous Reversion 

      Silva, Regiane Marinho da [UNIFESP]; Ko, Gui Mi [UNIFESP]; Silva, Rinaldo Florencio [UNIFESP]; Vieira, Ludmila Cabreira; Paula, Rafael Vicente de; Marumo, Julio Takehiro; Ikegami, Amanda; Bellini, Maria Helena (Humana Press Inc, 2018)
      Acute kidney injury (AKI) is an important health problem and can be caused by number of factors. The use of aminoglycosides, such as gentamicin, is one of these factors. Recently, an effort has been made to find biomarkers ...

    • Estudo dos fatores de risco e do impacto da lesão renal no transplante hepático 

      Narciso, Roberto Camargo [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2011-05-25)
      The acute and chronic renal diseases have distinct impacts on the outcome of liver transplantation (LTx). While the acute form determines high mortality soon after the transplantation procedure, most patients will recover ...

    • Eventos vitais estressores e lesão renal aguda em centros de terapia semi-intensiva e intensiva 

      Diniz, Denise Para [UNIFESP]; Marques, Daniella Aparecida [UNIFESP]; Blay, Sergio Luis [UNIFESP]; Schor, Nestor [UNIFESP] (Sociedade Brasileira de Nefrologia, 2012-03-01)
      INTRODUCTION: Several studies point out that pathophysiological changes related to stress may influence renal function and are associated with disease onset and evolution. However, we have not found any studies about the ...

    • Gentamicin-induced preconditioning of proximal tubular LLC-PK1 cells stimulates nitric oxide production but not the synthesis of heat shock protein 

      Pessoa, Edson de Andrade [UNIFESP]; Convento, Marcia.Bastos [UNIFESP]; Silva, Ronaldo Goncalves da [UNIFESP]; Oliveira, Accary Souza Bulle [UNIFESP]; Borges, Fernanda Teixeira [UNIFESP]; Schor, Nestor [UNIFESP] (Associação Brasileira de Divulgação Científica, 2009-07-01)
      Nephrotoxicity is the main side effect of antibiotics such as gentamicin. Preconditioning has been reported to protect against injuries as ischemia/reperfusion. The objective of the present study was to determine the effect ...

    • Glucose-Insulin Infusion Reduces Kidney Injury in an Experimental Model of Ischemic Nephropathy 

      Melo, Rosilene S. [UNIFESP]; Visona, Iria [UNIFESP]; Almeida, Waldemar S. [UNIFESP]; Campos, Alexandre Holthausen (Karger, 2010-01-01)
      Background/Aims: Intensive insulin therapy may reduce renal dysfunction during severe illness in adult patients. We evaluated the effects of insulin-glucose (IG) in normoglycemic rats subjected to ischemia-reperfusion ...

    • Immobilized Kidney 28-kDa Endostatin- Related (KES28kDa) Fragment Promotes Endothelial Cell Survival 

      Bellini, Maria Helena [UNIFESP]; Malpighi, Thiago Franca; Calvo, Fernanda Bernardes; Miranda, Adriana Regina; Spencer, Patrick Jack; Cichy, Milena Cristina [UNIFESP]; Simons, Simone Michaela; Chudzinski Tavassi, Ana Marisa; Santos, Marinilce Fagundes dos; Rodrigues, Consuelo Junqueira; Schor, Nestor [UNIFESP] (Karger, 2010-01-01)
      Background/Objective: Renal ischemia-hypoxia is a leading cause of acute kidney injury (AKI). Ischemia causes extracellular matrix breakdown of the tubular basement membrane. Endostatin (ES) is the C-terminal fragment of ...

    • The impact of continuous renal replacement therapy on renal outcomes in dialysis-requiring acute kidney injury may be related to the baseline kidney function 

      de Souza Oliveira, Marisa Aparecida [UNIFESP]; Claizoni dos Santos, Thais Oliveira [UNIFESP]; Martins Monte, Julio Cesar; Batista, Marcelo Costa [UNIFESP]; Pereira, Virgilio Goncalves, Jr.; Cardoso dos Santos, Bento Fortunato; Pavao Santos, Oscar Fernando [UNIFESP]; Durao, Marcelino de Souza, Jr. [UNIFESP] (Biomed Central Ltd, 2017)
      Background: Many controversies exist regarding the management of dialysis-requiring acute kidney injury (D-AKI). No clear evidence has shown that the choice of dialysis modality can change the survival rate or kidney ...