Browsing by Subject "ACTH"
Now showing items 1-10 of 16
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Os 50 anos de uso do hormônio adrenocorticotrófico (ACTH) no Tratamento da Síndrome de West: revisão de literatura e protocolo da UNIFESP
(Liga Brasileira de Epilepsia (LBE), 2008-03-01)INTRODUCTION: It is extensively discussed in the literature the efficacy of ACTH in West Syndrome (WS) as well, dosage, best protocols and side effects. OBJECTIVE: Analyze and discuss the most recent and relevant publication ...
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The ACTH test in the diagnosis of hirsutism
(Associação Paulista de Medicina - APM, 1997-04-01)The ACTH test has been used to confirm the diagnosis of adrenal insufficiency and the classic and the non-classic adrenal hyperplasia due to the 3-HSD, 21 OH e 110H deficiencies. This article reviews the historical aspects ...
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Adenomas hipofisários produtores de ACTH: Aspectos neurocirúrgicos
(Academia Brasileira de Neurologia - ABNEURO, 2002-03-01)We report our experience with 19 cases of ACTH secreting pituitary adenomas. They were microadenomas in 50% of the cases, coming with the typical picture of the Cushing syndrome. The ACTH adenoma associated with other types ...
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Adrenocorticotropin-producing pituitary carcinoma with expression of c-erbB-2 and high PCNA index: A comparative study with pituitary adenomas and normal pituitary tissues
(Humana Press Inc, 1998-03-01)Pituitary carcinomas are very rare neoplasms with a poor prognosis. We report a case of Cushing's disease resulting from a pituitary carcinoma in a ZZ-yr-old female, who died of massive hepatic failure. At autopsy, there ...
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Atividade Enzimática da 21-Hidroxilase e da 3beta-Hidroxiesteróide Desidrogenase em Mulheres Hirsutas com e sem Anovulação Crônica
(Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, 2000-10-01)Purpose: to test the adrenal function by a potent stimulus to its reticular layer verifying 3beta-hydroxysteroid dehy-drogenase (3beta-HSD) and 21-hydroxylase (21OH) enzymatic activities. Methods: plasma concentrations of ...
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Effect of one month ketoconazole treatment on GH, cortisol and ACTH release after ghrelin, GHRP-6 and GHRH administration in patients with cushing s disease
(Sociedade Brasileira de Endocrinologia e Metabologia, 2007-10-01)GH responses to ghrelin, GHRP-6, and GHRH in Cushing s disease (CD) are markedly blunted. There is no data about the effect of reduction of cortisol levels with steroidogenesis inhibitors, like ketoconazole, on GH secretion ...
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Effects of ghrelin, GH-releasing peptide-6 (GHRP-6) and GHRH on GH, ACTH and cortisol release in hyperthyroidism before and after treatment
(Springer, 2010-12-01)In thyrotoxicosis GH responses to stimuli are diminished and the hypothalamic-pituitary-adrenal axis is hyperactive. There are no data on ghrelin or GHRP-6-induced GH, ACTH and cortisol release in treated hyperthyroidism. ...
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GH-releasing peptide (GHRP-6)-induced ACTH release in patients with Addison's disease: Effect of glucocorticoid withdrawal
(Editrice Kurtis S R L, 2003-02-01)GH releasing peptide (GHRP-6) is a synthetic hexapeptide with potent GH releasing activity both in man and in animals. This peptide is also able to stimulate ACTH and cortisol (F) release. It has been suggested that the ...
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Ghrelin and GHRP-6-induced ACTH and cortisol release in thyrotoxicosis
(Springer, 2009-12-01)Thyrotoxicosis might alter the hypothalamic-pituitary-adrenal (HPA) axis. We evaluated the effects of ghrelin and GHRP-6 on the HPA axis in 20 hyperthyroid patients and in 9 controls. Mean basal cortisol (mu g/dl) and ACTH ...
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GHRP-6 is able to stimulate cortisol and ACTH release in patients with Cushing's disease: Comparison with DDAVP
(Editrice Kurtis S R L, 2003-03-01)It has been shown that hexarelin stimulates ACTH and cortisol secretion in patients with Cushing's disease. The ACTH release induced by this peptide is 7-fold greater than that obtained by hCRH. The mechanism of action of ...
