Now showing items 1-4 of 4

    • ACE activity is modulated by kinin B-2 receptor 

      Sabatini, Regiane Angelica [UNIFESP]; Guimarães, Paola Bianchi [UNIFESP]; Fernandes, Liliam [UNIFESP]; Reis, Felipe Castellani Gomes dos [UNIFESP]; Bersanetti, Patricia Alessandra [UNIFESP]; Mori, Marcelo Alves da Silva [UNIFESP]; Navarro, Alberto [UNIFESP]; Hilzendeger, Aline Mourão [UNIFESP]; Santos, Edson Lucas dos [UNIFESP]; Andrade, Maria C. C. [UNIFESP]; Chagas, Jair Ribeiro [UNIFESP]; Pesquero, Jorge L.; Casarini, Dulce Elena [UNIFESP]; Bader, Michael [UNIFESP]; Carmona, Adriana Karaoglanovic [UNIFESP]; Pesquero, João Bosco [UNIFESP] (Lippincott Williams & Wilkins, 2008-03-01)
      Angiotensin-converting enzyme (ACE) is an ectoprotein able to modulate the activity of a plethora of compounds, among them angiotensin I and bradykinin. Despite several decades of research, new aspects of the mechanism of ...

    • ACE activity is modulated by the enzyme alpha-galactosidase A 

      Batista, Elice Carneiro; Carvalho, Luiz Roberto; Casarini, Dulce Elena [UNIFESP]; Carmona, Adriana Karaoglanovic; Santos, Edson Lucas dos; Silva, Elton Dias da; Santos, Robson Augusto dos; Nakaie, Clovis Ryuichi; Munoz Rojas, Maria Veronica; Oliveira, Suzana Macedo de; Bader, Michael; D'Almeida, Vania [UNIFESP]; Martins, Ana Maria [UNIFESP]; Souza, Kely de Picoly; Pesquero, Joao Bosco [UNIFESP] (Springer, 2011-01-01)
      Fabry disease is a multisystem X-linked disorder resulting from alpha-galactosidase A (alpha-GalA) gene mutations leading to the accumulation of globotriaosylceramide mainly in endothelium compromising heart, kidney, and ...

    • Angiotensin I-converting enzyme inhibitor peptides derived from the endostatin-containing NC1 fragment of human collagen XVIII 

      Farias, S. L.; Sabatini, R. A.; Sampaio, T. C.; Hirata, I. Y.; Cezari, MHS; Juliano, M. A.; Sturrock, E. D.; Carmona, A. K.; Juliano, L. (Walter de Gruyter & Co, 2006-05-01)
      Extracellular matrix and soluble plasma proteins generate peptides that regulate biological activities such as cell growth, differentiation and migration. Bradykinin, a peptide released from kininogen by kallikreins, ...

    • Identification of novel bradykinin-potentiating peptides (BPPs) in the venom gland of a rattlesnake allowed the evaluation of the structure-function relationship of BPPs 

      Gomes, Claudiana L.; Konno, Katsuhiro; Conceição, Isaltino Marcelo da [UNIFESP]; Ianzer, Danielle; Yamanouye, Norma; Prezoto, Benedito C.; Assakura, Marina T.; Radis-Baptista, Gandhi; Yamane, Tetsuo; Santos, Robson A.; Camargo, Antonio C. M. de; Hayashi, Mirian A. F. (Elsevier B.V., 2007-11-01)
      Aiming to extend the knowledge about the diversity of bradykinin-potentiating peptides (BPPs) and their precursor proteins, a venom gland cDNA library from the South American rattlesnake (Crotalus dursissus terrificus, ...