Browsing by Subject "ACE"

Now showing items 1-10 of 13

    • ACE activity is modulated by kinin B-2 receptor 

      Sabatini, Regiane Angelica [UNIFESP]; Guimarães, Paola Bianchi [UNIFESP]; Fernandes, Liliam [UNIFESP]; Reis, Felipe Castellani Gomes dos [UNIFESP]; Bersanetti, Patricia Alessandra [UNIFESP]; Mori, Marcelo Alves da Silva [UNIFESP]; Navarro, Alberto [UNIFESP]; Hilzendeger, Aline Mourão [UNIFESP]; Santos, Edson Lucas dos [UNIFESP]; Andrade, Maria C. C. [UNIFESP]; Chagas, Jair Ribeiro [UNIFESP]; Pesquero, Jorge L.; Casarini, Dulce Elena [UNIFESP]; Bader, Michael [UNIFESP]; Carmona, Adriana Karaoglanovic [UNIFESP]; Pesquero, João Bosco [UNIFESP] (Lippincott Williams & Wilkins, 2008-03-01)
      Angiotensin-converting enzyme (ACE) is an ectoprotein able to modulate the activity of a plethora of compounds, among them angiotensin I and bradykinin. Despite several decades of research, new aspects of the mechanism of ...

    • ACE activity is modulated by the enzyme alpha-galactosidase A 

      Batista, Elice Carneiro; Carvalho, Luiz Roberto; Casarini, Dulce Elena [UNIFESP]; Carmona, Adriana Karaoglanovic; Santos, Edson Lucas dos; Silva, Elton Dias da; Santos, Robson Augusto dos; Nakaie, Clovis Ryuichi; Munoz Rojas, Maria Veronica; Oliveira, Suzana Macedo de; Bader, Michael; D'Almeida, Vania [UNIFESP]; Martins, Ana Maria [UNIFESP]; Souza, Kely de Picoly; Pesquero, Joao Bosco [UNIFESP] (Springer, 2011-01-01)
      Fabry disease is a multisystem X-linked disorder resulting from alpha-galactosidase A (alpha-GalA) gene mutations leading to the accumulation of globotriaosylceramide mainly in endothelium compromising heart, kidney, and ...

    • ACE I/D genotype-related increase in ACE plasma activity is a better predictor for schizophrenia diagnosis than the genotype alone 

      Gadelha, Ary [UNIFESP]; Yonamine, Camila M. [UNIFESP]; Ota, Vanessa K. [UNIFESP]; Oliveira, Vitor [UNIFESP]; Sato, Joao Ricardo; Belangero, Sintia I. [UNIFESP]; Bressan, Rodrigo A. [UNIFESP]; Hayashi, Mirian A. F. [UNIFESP] (Elsevier B.V., 2015-05-01)
      Background: Angiotensin-I converting enzyme (ACE) is a key component of the renin-angiotensin system(RAS). Although the several contradictory data, ACE has been associated with schizophrenia (SCZ) pathophysiology. Here the ...

    • Angiotensin I-converting enzyme (ACE) activity and expression in rat central nervous system after sleep deprivation 

      Visniauskas, Bruna [UNIFESP]; Oliveira, Vitor [UNIFESP]; Carmona, Adriana K. [UNIFESP]; D'Almeida, Vania [UNIFESP]; Melo, Robson L. de; Tufik, Sergio [UNIFESP]; Chagas, Jair R. [UNIFESP] (Walter de Gruyter & Co, 2011-04-01)
      Proteases are essential either for the release of neuropeptides from active or inactive proteins or for their inactivation. Neuropeptides have a fundamental role in sleep-wake cycle regulation and their actions are also ...

    • Angiotensin II Binding to Angiotensin I-Converting Enzyme Triggers Calcium Signaling 

      Guimarães, Paola Bianchi [UNIFESP]; Alvarenga, Erika Costa [UNIFESP]; Siqueira, Paula D. [UNIFESP]; Paredes-Gamero, Edgar Julian [UNIFESP]; Sabatini, Regiane Angelica [UNIFESP]; Morais, Rafael Leite Tavares de [UNIFESP]; Reis, Rosana I.; Santos, Edson L.; Teixeira, Luis Gustavo de Deus [UNIFESP]; Casarini, Dulce Elena [UNIFESP]; Martin, Renan Paulo [UNIFESP]; Shimuta, Suma Imura [UNIFESP]; Carmona, Adriana Karaoglanovic [UNIFESP]; Nakaie, Clovis Ryuichi [UNIFESP]; Jasiulionis, Miriam Galvonas [UNIFESP]; Ferreira, Alice Teixeira [UNIFESP]; Pesquero, Jorge L.; Oliveira, Suzana M. [UNIFESP]; Bader, Michael [UNIFESP]; Costa-Neto, Claudio M.; Pesquero, João Bosco [UNIFESP] (Lippincott Williams & Wilkins, 2011-05-01)
      Angiotensin (Ang) I-converting enzyme (ACE) is involved in the control of blood pressure by catalyzing the conversion of Ang I into the vasoconstrictor Ang II and degrading the vasodilator peptide bradykinin. Human ACE ...

    • Atividade das Oligopeptidases Ndel1 e ECA na Esquizofrenia e no Transtorno Bipolar 

      Mas, Caroline Dal [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2019-04-25)
      Schizophrenia (SCZ) and bipolar disorder (BD) are severe and disabling mental disorders (MDs), which share pathophysiological and symptomatological characteristics. Until the present, the neurobiological and etiological ...

    • Evidence that kinin B-2 receptor expression is upregulated by endothelial overexpression of B-1 receptors 

      Rodrigues, Eliete da Silva [UNIFESP]; Silva, Rafael Filippelli da [UNIFESP]; Martin, Renan Paulo [UNIFESP]; Oliveira, Suzana Macedo de [UNIFESP]; Nakaie, Clovis Ryuichi [UNIFESP]; Sabatini, Regiane Angélica [UNIFESP]; Merino, Vanessa Ferreira; Pesquero, João Bosco [UNIFESP]; Bader, Michael [UNIFESP]; Shimuta, Suma Imura [UNIFESP] (Elsevier B.V., 2013-04-01)
      Bradykinin (BK) and des-Arg(9)-bradykinin (DBK) of kallikrein-kinin system exert its effects mediated by the B-2 (B2R) and B-1 (B1R) receptors, respectively. It was already shown that the deletion of kinin B1R or of B2R ...

    • Kallikrein-kinin system in hepatic experimental models 

      Kouyoumdjian, Maria [UNIFESP]; Nagaoka, Márcia Regina [UNIFESP]; Borges, Durval Rosa [UNIFESP] (Elsevier B.V., 2005-08-01)
      The purpose of this brief review is to describe some characteristics of the kallikrein-kinin system (KKS) in the liver. the liver synthesizes kininogens and prekallikrein and the synthesis of both proteins is increased in ...

    • Neuropeptidases in psychiatric disorders 

      Nani, João Victor; Almeida, Priscila G. C.; Hayashi, Mirian [UNIFESP] (Elsevier, 2021)
      Psychiatric disorders (PDs), such as schizophrenia (SCZ), bipolar disorder (BD), and major depression disorder (MDD) are characterized by disturbances in the functioning of the CNS. These mental disorders have attracted ...

    • Neuropeptides and oligopeptidases in schizophrenia 

      Rodriguez, Benjamín [UNIFESP]; Nani, João Victor [UNIFESP]; Almeida, Priscila G. C. [UNIFESP]; Brietzke, Elisa; Lee, Richard S.; Hayashi, Mirian A. F. [UNIFESP] (Pergamon Press, 2020-01)
      Schizophrenia (SCZ) is a complex psychiatric disorder with severe impact on patient's livelihood. In the last years, the importance of neuropeptides in SCZ and other CNS disorders has been recognized, mainly due to their ...