Now showing items 1-17 of 17

    • Biosilicate (R) and low-level laser therapy improve bone repair in osteoporotic rats 

      Bossini, Paulo Sergio; Renno, Ana Claudia Muniz [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP]; Fangel, Renan; Peitl, Oscar; Zanotto, Edgar Dutra; Parizotto, Nivaldo Antonio (Wiley-Blackwell, 2011-03-01)
      The aim of this study was to investigate the effects of a novel bioactive material (Biosilicate (R)) and low-level laser therapy (LLLT) on bone fracture consolidation in osteoporotic rats. Forty female Wistar rats were ...
    • Biosilicate/PLGA osteogenic effects modulated by laser therapy: In vitro and in vivo studies 

      Fernandes, Kelly Rossetti [UNIFESP]; Magri, Angela Maria Paiva [UNIFESP]; Kido, Hueliton Wilian [UNIFESP]; Parisi, Julia Risso; Assis, Livia [UNIFESP]; Fernandes, Kristianne Porta Santos; Mesquita Ferrari, Raquel Agnelli; Martins, V. C.; Plepis, Ana M.; Zanotto, Edgar Dutra; Peitl Filho, Oscar; Renno, Ana Claudia Muniz [UNIFESP] (Elsevier Science Sa, 2017)
      The main purpose of the present work was to evaluate if low laser level therapy (LLLT) can improve the effects of Biosilicate®/PLGA (BS/PLGA) composites on cell viability and bone consolidation using a tibial defects of ...
    • Characterization and biocompatibility of a fibrous glassy scaffold 

      Gabbai-Armelin, Paulo Roberto; Souza, M. T.; Kido, Hueliton Wilian; Tim, Carla Roberta; Bossini, Paulo Sergio [UNIFESP]; Fernandes, Kelly Rossetti [UNIFESP]; Magri, Angela Maria Paiva [UNIFESP]; Parizotto, Nivaldo Antonio; Fernandes, Kristianne Porta Santos; Mesquita-Ferrari, Raquel Agnelli; Ribeiro, Daniel Araki [UNIFESP]; Zanotto, Edgar Dutra; Peitl Filho, Oscar [UNIFESP]; Renno, Ana Claudia Muniz [UNIFESP] (Wiley, 2017)
      Bioactive glasses (BGs) are known for their ability to bond to living bone and cartilage. In general, they are readily available in powder and monolithic forms, which are not ideal for the optimal filling of bone defects ...
    • Characterization and biological evaluation of the introduction of PLGA into biosilicate 

      Fernandes, Kelly Rossetti [UNIFESP]; Magri, Angela Maria Paiva [UNIFESP]; Kido, Hueliton Wilian [UNIFESP]; Ueno, Fabio Roberto [UNIFESP]; Assis, Livia [UNIFESP]; Fernandes, Kristianne Porta Santos; Mesquita Ferrari, Raquel Agnelli; Martins, V. C.; Plepis, Ana M.; Zanotto, Edgar Dutra; Peitl Filho, Oscar; Ribeiro, Daniel Araki [UNIFESP]; Van den Beucken, Jeroen J.; Renno, Ana Claudia Muniz [UNIFESP] (Wiley, 2017)
      The aims of this study were to characterize different BS/PLGA composites for their physicochemical and morphological characteristics and evaluate the in vitro and in vivo biological performance. The physicochemical and ...
    • Characterization and in Vivo Biological Performance of Biosilicate 

      Renno, Ana Claudia Muniz [UNIFESP]; Bossini, Paulo Sergio [UNIFESP]; Crovace, Murilo Camuri; Rodrigues, Ana Candida Martins; Zanotto, Edgar Dutra; Parizotto, Nivaldo Antonio (Hindawi Publishing Corporation, 2013-01-01)
      After an introduction showing the growing interest in glasses and glass-ceramics as biomaterials used for bone healing, we describe a new biomaterial named Biosilicate. Biosilicate is the designation of a group of fully ...
    • Effect of 830nm Laser Phototherapy on Osteoblasts Grown in Vitro on Biosilicate (R) Scaffolds 

      Renno, Ana Claudia Muniz [UNIFESP]; McDonnell, Pauline Ann; Crovace, Murilo Camuri; Zanotto, Edgar Dutra; Laakso, Liisa (Mary Ann Liebert Inc, 2010-02-01)
      Objective: the purpose of this study was (i) to develop a method for successfully seeding osteoblasts onto a glass-ceramic scaffold designed for use in clinical settings, and (ii) to determine whether the application of ...
    • Effect of a new bioactive fibrous glassy scaffold on bone repair 

      Gabbai-Armelin, Paulo Roberto; Souza, Marina Trevelin; Kido, Hueliton Wilian; Tim, Carla Roberta; Bossini, Paulo Sergio [UNIFESP]; Magri, Angela Maria Paiva [UNIFESP]; Fernandes, Kelly Rossetti [UNIFESP]; Pastor, Fabio Alexandre Casarin; Zanotto, Edgar Dutra; Parizotto, Nivaldo Antonio; Peitl Filho, Oscar; Renno, Ana Claudia Muniz [UNIFESP] (Springer, 2015-05-01)
      Researchers have investigated several therapeutic approaches to treat non-union fractures. Among these, bioactive glasses and glass ceramics have been widely used as grafts. This class of biomaterial has the ability to ...
    • Effects of Biosilicate (R) Scaffolds and Low-Level Laser Therapy on the Process of Bone Healing 

      Pinto, Karina Nogueira Zambone; Tim, Carla Roberta; Crovace, Murilo Camuri; Matsumoto, Mariza Akemi; Parizotto, Nivaldo Antonio; Zanotto, Edgar Dutra; Peitl, Oscar; Renno, Ana Claudia Muniz [UNIFESP] (Mary Ann Liebert Inc, 2013-06-01)
      Objective: This study aimed to investigate the in vivo tissue performance of the association of Biosilicate (R) scaffolds and low-level laser therapy (LLLT) in a tibial bone defects model in rats. Background data: Many ...
    • Effects of biosilicate and bioglass 45S5 on tibial bone consolidation on rats: a biomechanical and a histological study 

      Granito, Renata Neves; Ribeiro, Daniel Araki [UNIFESP]; Renno, Ana Claudia Muniz [UNIFESP]; Ravagnani, Christian; Bossini, Paulo Sergio; Peitl-Filho, Oscar; Zanotto, Edgar Dutra; Parizotto, Nivaldo Antonio; Oishi, Jorge (Springer, 2009-12-01)
      The purpose of this study was to investigate the effects of Bioglass 45S5(A (R)) and Biosilicate(A (R)), on bone defects inflicted on the tibia of rats. Fifty male Wistar rats were used in this study, and divided into five ...
    • Histopathological, cytotoxicity and genotoxicity evaluation of Biosilicate (R) glass-ceramic scaffolds 

      Kido, Hueliton Wilian; Oliveira, Poliani de; Parizotto, Nivaldo Antonio; Crovace, Murilo Camuri; Zanotto, Edgar Dutra; Peitl-Filho, Oscar; Fernandes, Kristianne Porta Santos; Mesquita Ferrari, Raquel Agnelli; Ribeiro, Daniel Araki [UNIFESP]; Renno, Ana Claudia Muniz [UNIFESP] (Wiley-Blackwell, 2013-03-01)
      This study evaluated the biocompatibility of Biosilicate (R) scaffolds by means of histopathological, cytotoxicity, and genotoxicity analysis. the histopathologic analysis of the biomaterial was performed using 65 male ...
    • In vivo biological performance of a novel highly bioactive glass-ceramic (Biosilicate (R)): A biomechanical and histomorphometric study in rat tibial defects 

      Granito, Renata Neves; Renno, Ana Claudia Muniz [UNIFESP]; Ravagnani, Christian; Bossini, Paulo Sergio; Mochiuti, Daniel; Jorgetti, Vanda; Driusso, Patricia; Peitl, Oscar; Zanotto, Edgar Dutra; Parizotto, Nivaldo Antonio; Oishi, Jorge (Wiley-Blackwell, 2011-04-01)
      This study aimed to investigate bone responses to a novel bioactive fully crystallized glass-ceramic of the quaternary system P(2)O(5)-Na(2)O-CaO-SiO(2) (Biosilicates (R)). Although a previous study demonstrated positive ...
    • Incorporation of bioactive glass in calcium phosphate cement: An evaluation 

      Renno, Ana Claudia Muniz [UNIFESP]; van de Watering, F. C. J.; Nejadnik, M. R.; Crovace, Murilo Camuri; Zanotto, Edgar Dutra; Wolke, J. G. C.; Jansen, J. A.; van den Beucken, Jeroen J. J. P. (Elsevier B.V., 2013-03-01)
      Bioactive glasses (BGs) are known for their unique ability to bond to living bone. Consequently, the incorporation of BGs into calcium phosphate cement (CPC) was hypothesized to be a feasible approach to improve the ...
    • Incorporation of bioactive glass in calcium phosphate cement: Material characterization and in vitro degradation 

      Renno, Ana Claudia Muniz [UNIFESP]; Nejadnik, M. R.; van de Watering, F. C. J.; Crovace, Murilo Camuri; Zanotto, Edgar Dutra; Hoefnagels, J. P. M.; Wolke, J. G. C.; Jansen, J. A.; van den Beucken, Jeroen J. J. P. (Wiley-Blackwell, 2013-08-01)
      Calcium phosphate cements (CPCs) have been widely used as an alternative to biological grafts due to their excellent osteoconductive properties. Although degradation has been improved by using poly(D,L-lactic-co-glycolic) ...
    • Injectable composites based on biosilicate (R) and alginate: handling and in vitro characterization 

      Gabbai-Armelin, Paulo Roberto [UNIFESP]; Cardoso, D. Alves; Zanotto, Edgar Dutra; Peitl, Oscar; Leeuwenburgh, S. C. G.; Jansen, J. A.; Renno, Ana Claudia Muniz [UNIFESP]; van den Beucken, Jeroen J. J. P. (Royal Soc Chemistry, 2014-01-01)
      The objective of the study was to prepare an injectable composite for bone regeneration based on the combination of a highly bioactive glass-ceramic (Biosilicate (R)) and alginate by optimizing the ratio of Biosilicate ...
    • New highly bioactive crystallization-resistant glass for tissue engineering applications 

      Souza, Marina Trevelin; Renno, Ana Claudia Muniz [UNIFESP]; Peitl, Oscar; Zanotto, Edgar Dutra (Lop Publishing Ltd, 2017)
      Bioactive glasses are able to chemically bond to hard and soft tissues and have been proposed and used for tissue regeneration in several dentistry and medical applications. However, the majority of bioactive glass ...
    • Porous bioactive scaffolds: characterization and biological performance in a model of tibial bone defect in rats 

      Kido, Hueliton Wilian; Tim, Carla Roberta; Bossini, Paulo Sergio [UNIFESP]; Parizotto, Nivaldo Antonio; Castro, Cynthia Aparecida de; Crovace, Murilo Camuri; Rodrigues, Ana Candida Martins; Zanotto, Edgar Dutra; Peitl Filho, Oscar; Anibal, Fernanda de Freitas; Renno, Ana Claudia Muniz [UNIFESP] (Springer, 2015-02-01)
      The aim of this study was to evaluate the effects of highly porous Biosilicate (R) scaffolds on bone healing in a tibial bone defect model in rats by means of histological evaluation (histopathological and immunohistochemistry ...
    • Putty-like bone fillers based on CaP ceramics or Biosilicate (R) combined with carboxymethylcellulose: Characterization, optimization, and evaluation 

      Gabbai-Armelin, Paulo Roberto [UNIFESP]; Renno, Ana Claudia Muniz [UNIFESP]; Crovace, Murilo Camuri; Magri, Angela Maria Paiva [UNIFESP]; Zanotto, Edgar Dutra; Peitl, Oscar; Leeuwenburgh, Sander C. G.; Jansen, John A.; van den Beucken, Jeroen J. J. P. (Sage Publications Ltd, 2017)
      Calcium phosphates and bioactive glass ceramics have been considered promising biomaterials for use in surgeries. However, their moldability should be further enhanced. We here thereby report the handling, physicochemical ...