Now showing items 1-1 of 1

    • Cruzain inhibition by hydroxymethylnitrofurazone and nitrofurazone: investigation of a new target in Trypanosoma cruzi 

      Trossini, Gustavo H. G.; Malvezzi, Alberto; T-do Amaral, Antonia; Rangel-Yagui, Carlota Oliveira; Izidoro, Mario A. [UNIFESP]; Cezari, Maria Helena S. [UNIFESP]; Juliano, Luiz [UNIFESP]; Chin, Chung Man; Menezes, Carla M. S.; Ferreira, Elizabeth Igne (Taylor & Francis Ltd, 2010-02-01)
      Nitrofurazone (NF) and its derivative, hydroxymethylnitrofurazone (NFOH), have presented antichagasic activity. NFOH has higher activity and lower mutagenicity. the aim of this work was to assess whether NF and its derivative ...