Now showing items 1-2 of 2

    • Increased blood pressure and water intake in transgenic mice expressing rat tonin in the brain 

      Cardoso, Cibele C.; Alenina, Natalia; Ferreira, Anderson J.; Qadri, Fatimunnisa; Lima, Mercia P.; Gross, Volkmar; Todiras, Mihail; Pesquero, Joao B. [UNIFESP]; Pesquero, Jorge L.; Bader, Michael (Walter de Gruyter & Co, 2010-04-01)
      Tonin is a serine proteinase of the kallikrein family that can produce angiotensin II directly from angiotensinogen. To clarify the importance of this enzyme for central nervous control of the cardiovascular system, we ...

    • Leptin regulates ACE activity in mice 

      Hilzendeger, Aline Mourão [UNIFESP]; Morais, Rafael Leite [UNIFESP]; Todiras, Mihail; Plehm, Ralph; Goncalves, Andrey da Costa; Qadri, Fatimunnisa; Araujo, Ronaldo Carvalho [UNIFESP]; Gross, Volkmar; Nakaie, Clovis Ryuichi [UNIFESP]; Casarini, Dulce Elena; Carmona, Adriana Karaoglanovic [UNIFESP]; Bader, Michael; Pesquero, Joao Bosco [UNIFESP] (Springer, 2010-09-01)
      Leptin is a hormone related to metabolism. It also influences blood pressure, but the mechanisms triggered in this process are not yet elucidated. Angiotensin-I converting enzyme (ACE) regulates cardiovascular functions ...