Now showing items 1-9 of 9

    • Análise dos possíveis efeitos preventivos do canabidiol em um modelo animal de esquizofrenia: a ativação imune pela administração de poly i:c 

      Peres, Fernanda Fiel [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2015-11-30)
      Introdução: A esquizofrenia é um transtorno psiquiátrico de alta prevalência cujo tratamento farmacológico está associado a efeitos colaterais importantes e a altas taxas de refratariedade. O desenvolvimento de novas ...
    • Antipsychotic Profile of Cannabidiol and Rimonabant in an Animal Model of Emotional Context Processing in Schizophrenia 

      Levin, Raquel [UNIFESP]; Almeida, Valeria [UNIFESP]; Peres, Fernanda Fiel [UNIFESP]; Calzavara, Mariana Bendlin [UNIFESP]; Silva, Neide Derci da [UNIFESP]; Suiama, Mayra Akimi [UNIFESP]; Niigaki, Suzy Tamie [UNIFESP]; Zuardi, Antonio Waldo [UNIFESP]; Hallak, Jaime Eduardo Cecilio; Crippa, Jose Alexandre de Souza; Abilio, Vanessa Costhek [UNIFESP] (Bentham Science Publ Ltd, 2012-11-01)
      Objectives: Clinical and neurobiological findings suggest that cannabinoids and their receptors are implicated in schizophrenia. Cannabidiol (CBD), a non-psychotomimetic compound of the Cannabis sativa plant, has been ...
    • Cannabidiol as a Promising Strategy to Treat and Prevent Movement Disorders? 

      Peres, Fernanda Fiel [UNIFESP]; Lima, Alvaro C.; Hallak, Jaime E. C.; Crippa, José Alexandre de Souza [UNIFESP]; Silva, Regina Helena da [UNIFESP]; Abilio, Vanessa Costhek [UNIFESP] (Frontiers Media Sa, 2018)
      Movement disorders such as Parkinson's disease and dyskinesia are highly debilitating conditions linked to oxidative stress and neurodegeneration. When available, the pharmacological therapies for these disorders are still ...
    • Cannabidiol exhibits anxiolytic but not antipsychotic property evaluated in the social interaction test 

      Almeida, Valéria de [UNIFESP]; Levin, Raquel [UNIFESP]; Peres, Fernanda Fiel [UNIFESP]; Niigaki, Suzy Tamie [UNIFESP]; Calzavara, Mariana Bendlin [UNIFESP]; Zuardi, Antonio Waldo; Hallak, Jaime Eduardo Cecilio; Crippa, José Alexandre de Souza; Abílio, Vanessa Costhek [UNIFESP] (Elsevier B.V., 2013-03-05)
      Cannabidiol (CBD), a non-psychotomimetic compound of the Cannabis sativa, has been reported to have central therapeutic actions, such as antipsychotic and anxiolytic effects. We have recently reported that Spontaneously ...
    • Cannabidiol Prevents Motor and Cognitive Impairments Induced by Reserpine in Rats 

      Peres, Fernanda Fiel [UNIFESP]; Leyin, Raquel [UNIFESP]; Suiama, Mayra Akimi [UNIFESP]; Diana, Mariana Cepollaro [UNIFESP]; Gouvea, Douglas Albuquerque [UNIFESP]; Almeida, Valeria [UNIFESP]; Santos, Camila Mauricio [UNIFESP]; Lungato, Lisandro [UNIFESP]; Zuardi, Antonio W.; Hallak, Jaime E. C.; Crippa, Jose A.; D'Almeida, Vania [UNIFESP]; Silva, Regina Helena da [UNIFESP]; Abilio, Vanessa Costhek [UNIFESP] (Frontiers Media Sa, 2016)
      Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that presents antipsychotic, anxiolytic, anti-inflammatory, and neuroprotective effects. In Parkinson's disease patients, CBD is able to attenuate ...
    • Effects of cannabinoid drugs on the deficit of prepulse inhibition of startle in an animal model of schizophrenia: the SHR strain 

      Levin, Raquel [UNIFESP]; Peres, Fernanda Fiel [UNIFESP]; Almeida, Valeria [UNIFESP]; Calzavara, Mariana Bendlin [UNIFESP]; Zuardi, Antonio W.; Hallak, Jaime E. C.; Crippa, Jose Alexandre S.; Abilio, Vanessa Costhek [UNIFESP] (Frontiers Research Foundation, 2014-02-06)
      Clinical and neurobiological findings suggest that the cannabinoids and the endocannabinoid system may be implicated in the pathophysiology and treatment of schizophrenia. We described that the spontaneously hypertensive ...
    • Peripubertal exposure to environmental enrichment prevents schizophrenia-like behaviors in the SHR strain animal model 

      Santos, Camila Mauricio [UNIFESP]; Peres, Fernanda Fiel [UNIFESP]; Diana, Mariana Cepollaro [UNIFESP]; Justi, Veronica [UNIFESP]; Suiama, Mayra Akimi [UNIFESP]; Santana, Marcela Goncalves [UNIFESP]; Abilio, Vanessa Costhek [UNIFESP] (Elsevier Science Bv, 2016)
      Schizophrenia is a highly disabling mental disorder, in which genetics and environmental factors interact culminating in the disease. The treatment of negative symptoms and cognitive deficits with antipsychotics is currently ...
    • Peripubertal treatment with cannabidiol prevents the emergence of psychosis in an animal model of schizophrenia 

      Peres, Fernanda Fiel [UNIFESP]; Diana, Mariana Cepollaro [UNIFESP]; Suiama, Mayra Akimi [UNIFESP]; Justi, V. [UNIFESP]; Almeida, V. [UNIFESP]; Bressan, Rodrigo Affonseca [UNIFESP]; Zuardi, A. W.; Hallak, J. E.; Crippa, José Alexandre de Souza [UNIFESP]; Abilio, Vanessa Costhek [UNIFESP] (Elsevier Science Bv, 2016)
    • A schizophrenia-like behavioral trait in the SHR model: Applying confirmatory factor analysis as a new statistical tool 

      Peres, Fernanda Fiel [UNIFESP]; Eufrasio, Rai Alvares [UNIFESP]; Gouvea, Douglas Albuquerque [UNIFESP]; Dian, Mariana Cepollaro [UNIFESP]; Santos, Camila Mauricio [UNIFESP]; Swardfager, Walter; Abilio, Vanessa Costhek [UNIFESP]; Cogo-Moreira, Hugo [UNIFESP] (Pergamon-Elsevier Science Ltd, 2018)
      Questionnaires that assess symptoms of schizophrenia patients undergo strict statistical validation, often using confirmatory factor analysis (CFA). CFA allows testing the existence of a trait that both collectively explains ...