Now showing items 1-5 of 5

    • The Affective and Emotional Composite Temperament (AFECT) model and scale: A system-based integrative approach 

      Lara, Diogo R.; Bisol, Luisa W.; Brunstein, Miriam G.; Reppold, Caroline T.; Carvalho, Hudson W. de [UNIFESP]; Ottoni, Gustavo L. (Elsevier B.V., 2012-09-01)
      Based on many temperament frameworks, here we propose an integration of emotional and affective temperaments (the AFECT model), forming a common substrate for mood, behavior, personality and part of cognition. Temperament ...
    • Development and validity data of the Brazilian Internet Study on Temperament and Psychopathology (BRAINSTEP) 

      Lara, Diogo R.; Ottoni, Gustavo L.; Brunstein, Miriam G.; Frozi, Julia; Carvalho, Hudson W. de [UNIFESP]; Bisol, Luisa W. (Elsevier B.V., 2012-12-10)
      Background: the internet provides a research opportunity for psychiatry and psychology. This article presents the development and preliminary data of a large web-survey created to study how temperament relates to other ...
    • Is Flunarizine a Long-Acting Oral Atypical Antipsychotic? A Randomized Clinical Trial Versus Haloperidol for the Treatment of Schizophrenia 

      Bisol, Luisa W.; Brunstein, Miriam G.; Ottoni, Gustavo L.; Ramos, Fernanda L. P.; Borba, Daniela L.; Daltio, Claudiane Salles [UNIFESP]; Oliveira, Ricardo V. de; Paz, Gisele E. G.; Souza, Sayuri E. de [UNIFESP]; Bressan, Rodrigo Affonseca [UNIFESP]; Lara, Diogo R. (Physicians Postgraduate Press, 2008-10-01)
      Background: Flunarizine is known as a nonspecific calcium channel blocker that has been used for decades for the treatment of migraine, vertigo. and cognitive deficits related to cerebrovascular disorders. Flunarizine also ...
    • Polymorphisms in schizophrenia candidate gene UFD1L may contribute to cognitive deficits 

      Ota, Vanessa K. [UNIFESP]; Berberian, Arthur A. [UNIFESP]; Gadelha, Ary [UNIFESP]; Santoro, Marcos L. [UNIFESP]; Ottoni, Gustavo L.; Matsuzaka, Camila T. [UNIFESP]; Mari, Jair J. [UNIFESP]; Melaragno, Maria I. [UNIFESP]; Lara, Diogo R.; Smith, Marilia A. C. [UNIFESP]; Belangero, Sintia I. [UNIFESP]; Bressan, Rodrigo A. [UNIFESP] (Elsevier B.V., 2013-08-30)
      We aimed to investigate UFD1L polymorphisms in schizophrenia and in relation to cognition. A total of 299 cases and 363 controls were genotyped, and 130 patients completed nine neuropsychological tests. We found that ...
    • ZDHHC8 gene may play a role in cortical volumes of patients with schizophrenia 

      Ota, Vanessa K. [UNIFESP]; Gadelha, Ary [UNIFESP]; Assuncao, Idaiane B. [UNIFESP]; Santoro, Marcos L. [UNIFESP]; Christofolini, Denise M.; Bellucco, Fernanda T. [UNIFESP]; Santos-Filho, Airton F. [UNIFESP]; Ottoni, Gustavo L.; Lara, Diogo R.; Mari, Jair J. [UNIFESP]; Melaragno, Maria I. [UNIFESP]; Smith, Marilia A. C. [UNIFESP]; Bressan, Rodrigo A. [UNIFESP]; Belangero, Sintia I. [UNIFESP]; Jackowski, Andrea P. [UNIFESP] (Elsevier B.V., 2013-04-01)
      ZDHHC8 rs175174 polymorphism is located in 22q11.2 region and its role in brain volume has not been fully addressed. A total of 282 schizophrenia patients and 379 controls were genotyped. A sample of 138 patients underwent ...