Now showing items 1-6 of 6

    • Effects of short-term zidovudine exposure on mitochondrial DNA content and succinate dehydrogenase activity of rat skeletal muscle cells 

      Kiyomoto, Beatriz H. [UNIFESP]; Tengan, Celia H. [UNIFESP]; Godinho, Rosely O. [UNIFESP] (Elsevier B.V., 2008-05-15)
      Long-term use of zidovudine (AZT) may cause mitochondrial abnormalities in various tissues, including a toxic myopathy in AIDS patients associated with mitochondrial DNA (mtDNA) depletion. in the present study, we examine ...
    • Increase in parasympathetic tone by pyridostigmine prevents ventricular dysfunction during the onset of heart failure 

      Lataro, Renata M.; Silva, Carlos A. A.; Fazan, Rubens; Rossi, Marcos A.; Prado, Cibele M.; Godinho, Rosely O. [UNIFESP]; Salgado, Helio C. (Amer Physiological Soc, 2013-10-01)
      Heart failure (HF) is characterized by elevated sympathetic activity and reduced parasympathetic control of the heart. Experimental evidence suggests that the increase in parasympathetic function can be a therapeutic ...
    • INCREASED EXPRESSION of ACETYLCHOLINE RECEPTORS in the DIAPHRAGM MUSCLE of MDX MICE 

      Ghedini, Paulo C. [UNIFESP]; Viel, Tania A. [UNIFESP]; Honda, Luciana [UNIFESP]; Avellar, Maria Christina W. [UNIFESP]; Godinho, Rosely O. [UNIFESP]; Lima-Landman, Maria Teresa R. [UNIFESP]; Lapa, Antonio J. [UNIFESP]; Souccar, Caden [UNIFESP] (Wiley-Blackwell, 2008-12-01)
      The absence of dystrophin in Duchenne muscular dystrophy (DMD) and in the mutant mdx mouse causes muscle degeneration and disruption of the neuromuscular junction. Based on evidence from the denervation-like properties of ...
    • The kinin B-1 receptor regulates muscle-specific E3 ligases expression and is involved in skeletal muscle mass control 

      Parreiras-e-Silva, Lucas T.; Reis, Rosana I.; Santos, Geisa A.; Pires-Oliveira, Marcelo [UNIFESP]; Pesquero, Joao B. [UNIFESP]; Gomes, Marcelo D.; Godinho, Rosely O. [UNIFESP]; Costa-Neto, Claudio M. (Portland Press Ltd, 2014-08-01)
      Regulation of muscle mass depends on the balance between synthesis and degradation of proteins, which is under the-control of different signalling pathways regulated by hormonal, neural and nutritional stimuli. Such stimuli ...
    • Testosterone represses ubiquitin ligases atrogin-1 and Murf-1 expression in an androgen-sensitive rat skeletal muscle in vivo 

      Pires-Oliveira, Marcelo [UNIFESP]; Maragno, Ana Leticia G. C.; Parreiras-e-Silva, Lucas T.; Chiavegatti, Tiago [UNIFESP]; Gomes, Marcelo D.; Godinho, Rosely O. [UNIFESP] (Amer Physiological Soc, 2010-02-01)
      Pires-Oliveira M, Maragno AL, Parreiras-E-Silva LT, Chiavegatti T, Gomes MD, Godinho RO. Testosterone represses ubiquitin ligases atrogin-1 and Murf-1 expression in an androgen-sensitive rat skeletal muscle in vivo. J Appl ...
    • Vitamin E prevents cell death induced by mild oxidative stress in chicken skeletal muscle cells 

      Nunes, Viviane A. [UNIFESP]; Gozzo, Andrezza Justino [UNIFESP]; Cruz-Silva, Ilana [UNIFESP]; Juliano, Maria Aparecida [UNIFESP]; Viel, Tania A. [UNIFESP]; Godinho, Rosely O. [UNIFESP]; Meirelles, Flavio V.; Sampaio, Misako U. [UNIFESP]; Sampaio, Claudio A M [UNIFESP]; Araujo, Mariana S. [UNIFESP] (Elsevier B.V., 2005-07-01)
      Apoptosis and necrosis are two forms of cell death that can occur in response to various agents and oxidative damage. in addition to necrosis, apoptosis contributes to muscle fiber loss in various muscular dystrophies as ...