Now showing items 1-6 of 6

    • Antimicrobial Action of Biguanides on the Viability of Acanthamoeba Cysts and Assessment of Cell Toxicity 

      Mafra, Cecilia Sales Pires [UNIFESP]; Carrijo-Carvalho, Linda Christian [UNIFESP]; Chudzinski-Tavassi, Ana Marisa; Taguchi, Felipe Marques de Carvalho [UNIFESP]; Foronda, Annette Silva [UNIFESP]; Carvalho, Fabio Ramos de Souza [UNIFESP]; Freitas, Denise de [UNIFESP] (Assoc Research Vision Ophthalmology Inc, 2013-09-01)
      PURPOSE. To assess dose- and concentration-dependent rates of biguanides on the viability of Acanthamoeba cysts isolated from severe ulcerative keratitis, and to correlate cysticidal activites with cytotoxic profiles in ...
    • Cytotoxic activity and degradation patterns of structural proteins by corneal isolates of Acanthamoeba spp 

      Sant'ana, Viviane Peracini [UNIFESP]; Carrijo-Carvalho, Linda Christian [UNIFESP]; Foronda, Annette Silva [UNIFESP]; Chudzinski-Tavassi, Ana Marisa; Freitas, Denise de [UNIFESP]; Souza de Carvalho, Fabio Ramos [UNIFESP] (Springer, 2015-01-01)
      Proteolytic enzymes secreted by trophozoites (amoebic secretome) are suggested as the main virulence factor involved in the severity of Acanthamoeba keratitis. the degradation profile of the main glycoprotein components ...
    • In vitro amoebicidal activity of S-nitrosoglutathione and S-nitroso-N-acetylcysteine against trophozoites of Acanthamoeba castellanii 

      Cariello, Angelino Julio [UNIFESP]; Pereira de Souza, Gabriela Freitas; Foronda, Annette Silva [UNIFESP]; Zorat Yu, Maria Cecilia [UNIFESP]; Hofling-Lima, Ana Luisa [UNIFESP]; Oliveira, Marcelo Ganzarolli de (Oxford Univ Press, 2010-03-01)
    • Serine-like proteolytic enzymes correlated with differential pathogenicity in patients with acute Acanthamoeba keratitis 

      Souza Carvalho, F. R. de [UNIFESP]; Carrijo-Carvalho, L. C.; Chudzinski-Tavassi, A. M.; Foronda, Annette Silva [UNIFESP]; Freitas, D. de [UNIFESP] (Wiley-Blackwell, 2011-04-01)
      P>Acute ocular infection due to free-living amoebae of the genus Acanthamoeba is characterized by severe pain, loss of corneal transparency and, eventually, blindness. Proteolytic enzymes secreted by trophozoites of virulent ...
    • Therapeutic agents and biocides for ocular infections by free-living amoebae of Acanthamoeba genus 

      Carrijo-Carvalho, Linda Christian [UNIFESP]; Sant'ana, Viviane Peracini [UNIFESP]; Foronda, Annette Silva [UNIFESP]; de Freitas, Denise [UNIFESP]; de Souza Carvalho, Fabio Ramos [UNIFESP] (Elsevier Science Inc, 2017)
      Acanthamoeba keratitis is a sight-threatening infectious disease. Resistance of the cystic form of the protozoan to biocides and the potential toxicity of chemical compounds to corneal cells are the main concerns related ...
    • Twenty Years of Acanthamoeba Keratitis 

      Carvalho, Fabio Ramos de Souza [UNIFESP]; Foronda, Annette Silva [UNIFESP]; Mannis, M. J.; Hoefling-Lima, Ana Luisa [UNIFESP]; Belfort, R. [UNIFESP]; Freitas, Denise de [UNIFESP] (Lippincott Williams & Wilkins, 2009-06-01)
      Purpose: We described the rate of Acanthamoeba keratitis (AK) in a referral eye center in Sao Paulo, Brazil, through a retrospective review of clinical and laboratorial records of patients over 2 decades.Methods: From 1987 ...