Now showing items 1-19 of 19

    • Ability of New Vital Dyes to Stain Intraocular Membranes and Tissues in Ocular Surgery 

      Rodrigues, Eduardo B. [UNIFESP]; Penha, Fernando M. [UNIFESP]; Fiod Costa, Elaine De Paula [UNIFESP]; Maia, Mauricio [UNIFESP]; Dib, Eduardo [UNIFESP]; Moraes, Milton [UNIFESP]; Meyer, Carsten H.; Magalhaes, Octaviano [UNIFESP]; Melo, Gustavo Barreto [UNIFESP]; Stefano, Vinicius [UNIFESP]; Dias, Ana Beatriz [UNIFESP]; Farah, Michel Eid [UNIFESP] (Elsevier B.V., 2010-02-01)
      PURPOSE: To evaluate the ability of novel dyes to stain lens capsule (LC), internal limiting membrane (ILM), epiretinal membrane (ERM), and vitreous.DESIGN: Experimental study in animal and human donor eyes.METHODS: Thirteen ...
    • Biochemical Analysis and Decomposition Products of Indocyanine Green in Relation to Solvents, Dye Concentrations and Laser Exposure 

      Penha, Fernando M. [UNIFESP]; Rodrigues, Eduardo B. [UNIFESP]; Maia, Mauricio [UNIFESP]; Meyer, Carsten H.; Fiod Cost, Elaine de Paula [UNIFESP]; Dib, Eduardo [UNIFESP]; Bechara, Etelvino; Lourenco, Andreia [UNIFESP]; Lima Filho, Acacio A. S. [UNIFESP]; Freymueller, Edna H. [UNIFESP]; Farah, Michel Eid [UNIFESP]; Int Chromovitrectomy Collaboration (Karger, 2013-01-01)
      Purpose: To investigate pH, ions, osmolarity and precipitation of indocyanine green (ICG), as well as the profile of ICG decomposition products (DPs) after laser exposure and the interaction with quenchers. Methods: ICG ...
    • Corantes vitais em cromovitrectomia 

      Dib, Eduardo [UNIFESP]; Rodrigues, Eduardo Buchele [UNIFESP]; Maia, Maurício [UNIFESP]; Meyer, Carsten H.; Penha, Fernando Marcondes [UNIFESP]; Furlani, Bruno de Albuquerque [UNIFESP]; Costa, Elaine de Paula Fiod [UNIFESP]; Farah, Michel Eid [UNIFESP] (Conselho Brasileiro de Oftalmologia, 2009-12-01)
      The aim of this article is to present the current data with regard to the application of vital dyes during vitreoretinal surgery, chromovitrectomy, as well as to overview the current literature regarding the properties of ...
    • Detecção de bevacizumabe sub-retiniano após injeção intravítrea 

      Dib, Eduardo [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2010-08-25)
      Purpose: To evaluate subretinal detection of bevacizumab two hours after intravitreous injection of 1.25 mg in rabbit eyes. Methods: Anterior chamber paracentesis using a 30-gauge needle was performed in nine female ...
    • Effects of Light Exposure, pH, Osmolarity, and Solvent on the Retinal Pigment Epithelial Toxicity of Vital Dyes 

      Costa, Elaine F. [UNIFESP]; Barros, Nilana M. T. [UNIFESP]; Coppini, Larissa Pereira [UNIFESP]; Neves, Raquel L. [UNIFESP]; Carmona, Adriana K. [UNIFESP]; Penha, Fernando M. [UNIFESP]; Rodrigues, Eduardo B. [UNIFESP]; Dib, Eduardo [UNIFESP]; Magalhaes, Octaviano [UNIFESP]; Moraes-Filho, Milton N. [UNIFESP]; Lima Filho, Acacio A. S. [UNIFESP]; Maia, Mauricio [UNIFESP]; Farah, Michel E. [UNIFESP] (Elsevier B.V., 2013-04-01)
      PURPOSE: To investigate the in vitro effect of pH, osmolarity, solvent, and light interaction on currently used an l novel dyes to minimize dye-related retinal toxicity.DESIGN: Laboratory investigation.METHODS: Retinal ...
    • Effects of subretinal injection of patent blue and trypan blue in rabbits 

      Maia, Mauricio [UNIFESP]; Penha, Fernando [UNIFESP]; Rodrigues, Eduardo Buchele [UNIFESP]; Principe, Andre [UNIFESP]; Dib, Eduardo [UNIFESP]; Meyer, Carsten H. [UNIFESP]; Freymuller, Edna [UNIFESP]; Moraes, Nilva [UNIFESP]; Farah, Michel Eid [UNIFESP] (Taylor & Francis Inc, 2007-04-01)
      Purpose: To investigate the histologic and clinical effects of subretinal injection of patent blue (PB) and trypan blue (TB) in rabbits. Methods: Dutch-belted rabbits (n = 8) were vitrectomized followed by subretinal ...
    • In Vivo, in Vitro Toxicity and in Vitro Angiogenic Inhibition of Sunitinib Malate 

      Dib, Eduardo [UNIFESP]; Maia, Mauricio [UNIFESP]; Lima, Acacio de Souza; Fiod Costa, Elaine de Paula [UNIFESP]; Moraes-Filho, Milton Nunes de [UNIFESP]; Rodrigues, Eduardo Buechele [UNIFESP]; Penha, Fernando Marcondes [UNIFESP]; Coppini, Larissa Pereira [UNIFESP]; Tenorio de Barros, Nilana Meza [UNIFESP]; Sinigaglia Galli Coimbra, Rita de Cassia [UNIFESP]; Magalhaes Junior, Octaviano [UNIFESP]; Guerra, Tarcisio [UNIFESP]; Furlani, Bruno de Albuquerque [UNIFESP]; Freymuller, Edna [UNIFESP]; Farah, Michel Eid [UNIFESP] (Informa Healthcare, 2012-07-01)
      Purpose: To evaluate the in vivo and in vitro toxicity of sunitinib malate, a multikinase inhibitor molecule.Design: Experimental, Prospective, Controlled.Methods: Human retinal pigment epithelial (ARPE-19) and human ...
    • Morphologic and clinical effects of subretinal injection of indocyanine green and infracyanine green in rabbits 

      Penha, Fernando M. [UNIFESP]; Maia, Mauricio [UNIFESP]; Farah, Michel E. [UNIFESP]; Dib, Eduardo [UNIFESP]; Principe, Andre H. [UNIFESP]; Devin, Fracois; Rodrigues, Eduardo B.; Duprat, Joao P. [UNIFESP]; Freymueller, Edna [UNIFESP] (Mary Ann Liebert Inc, 2008-02-01)
      Purpose: the aim of this study was to determine the effects of subretinal injection of indocyanine green (ICG), infracyanine (IfCG), and balanced salt solution (BSS) in rabbits.Methods: Ten (10) animals were subjected to ...
    • Perspective on Fluid and Solid Dynamics in Different Pars Plana Vitrectomy Systems 

      Magalhaes, Octaviano [UNIFESP]; Maia, Mauricio [UNIFESP]; Rodrigues, Eduardo B. [UNIFESP]; Machado, Leonardo [UNIFESP]; Costa, Elaine F. [UNIFESP]; Maia, Andre [UNIFESP]; Moares-Filho, Milton N. [UNIFESP]; Dib, Eduardo [UNIFESP]; Farah, Michel Eid [UNIFESP] (Elsevier B.V., 2011-03-01)
      PURPOSE: To summarize current concepts and recent data from the literature about different vitrectomy machines and small-gauge systems based on physical laws.DESIGN: Interpretive essay.METHODS: Review and synthesis of ...
    • Preclinical investigation of the retinal biocompatibility of six novel vital dyes for chromovitrectomy 

      Rodrigues, Eduardo Buchele [UNIFESP]; Penha, Fernando Marcondes [UNIFESP]; Farah, Michel Eid [UNIFESP]; Costa, Elaine de Paula Fiod [UNIFESP]; Maia, Mauricio [UNIFESP]; Dib, Eduardo [UNIFESP]; Bottos, Juliana [UNIFESP]; Freymuller, Edna [UNIFESP]; Furlani, Bruno de Albuquerque [UNIFESP]; Meyer, Carsten H. [UNIFESP]; Magalhães, Octaviano [UNIFESP]; Lima-Filho, Acacio Alves Souza [UNIFESP]; Safatle, Angélica Mendonça de Vaz (Lippincott Williams & Wilkins, 2009-04-01)
      Purpose: To investigate the retinal biocompatibility of six novel vital dyes for chromovitrectomy.Methods: An amount of 0.05 mL of 0.5% and 0.05% light green (LG), fast green (FG), Evans blue (EB), brilliant blue (BriB), ...
    • Retinal and Ocular Toxicity in Ocular Application of Drugs and Chemicals - Part I: Animal Models and Toxicity Assays 

      Penha, Fernando Marcondes [UNIFESP]; Rodrigues, Eduardo B. [UNIFESP]; Maia, Mauricio [UNIFESP]; Dib, Eduardo [UNIFESP]; Costa, Elaine Fiod [UNIFESP]; Furlani, Bruno A. [UNIFESP]; Moraes Filho, Milton Nunes [UNIFESP]; Dreyfuss, Juliana L. [UNIFESP]; Bottos, Juliana [UNIFESP]; Farah, Michel E. [UNIFESP] (Karger, 2010-01-01)
      Aims: Experimental retinal research has gained great importance due to the ophthalmic pharmacotherapy era. An increasing number of drugs are constantly released into the market for the treatment of retinal diseases. in ...
    • Retinal Pigmented Epithelial Cells Cytotoxicity and Apoptosis through Activation of the Mitochondrial Intrinsic Pathway: Role of Indocyanine Green, Brilliant Blue and Implications for Chromovitrectomy 

      Penha, Fernando Marcondes [UNIFESP]; Pons, Marianne; Costa, Elaine Fiod [UNIFESP]; Tenorio Barros, Nilana Meza [UNIFESP]; Rodrigues, Eduardo Buchele; Cardoso, Emmerson Badaro [UNIFESP]; Dib, Eduardo [UNIFESP]; Maia, Mauricio [UNIFESP]; Marin-Castano, Maria E.; Farah, Michel Eid [UNIFESP] (Public Library Science, 2013-05-10)
      Purpose: To investigate the in vitro effect of four vital dyes on toxicity and apoptosis in a human retinal pigment epithelial (RPE) cell line.Methods: ARPE-19 cells were exposed to brilliant blue (BriB), methyl blue (MetB), ...
    • Staining Properties of Brilliant Blue Depending on Different Incubation Times and Solvents in Humans 

      Rodrigues, Eduardo B. [UNIFESP]; Maia, Mauricio [UNIFESP]; Penha, Fernando M. [UNIFESP]; Dib, Eduardo [UNIFESP]; Melo, Gustavo B. [UNIFESP]; Maia, Andre [UNIFESP]; Farah, Michel E. [UNIFESP]; Int Chromovitrectomy Collaboration [UNIFESP] (Karger, 2013-01-01)
      Purpose: Intravitreous injection of vital dyes, e.g. brilliant blue (BBG), promotes better visualization of the internal limiting membrane (ILM). This paper investigates the staining properties of BBG depending on different ...
    • Subretinal bevacizumab detection after intravitreous injection in rabbits 

      Dib, Eduardo [UNIFESP]; Maia, Mauricio [UNIFESP]; Longo-Maugeri, Ieda Maria [UNIFESP]; Martins, Maria Cristina [UNIFESP]; Mussalem, Juliana Sekeres [UNIFESP]; Squaiella, Carla Cristina [UNIFESP]; Penha, Fernando Marcondes [UNIFESP]; Magalhaes, Octaviano [UNIFESP]; Rodrigues, Eduardo Buchele [UNIFESP]; Farah, Michel Eid [UNIFESP] (Assoc Research Vision Ophthalmology Inc, 2008-03-01)
      PURPOSE. To evaluate subretinal detection of bevacizumab 2 hours after intravitreous injection of 1.25 mg in rabbit eyes.METHODS. Anterior chamber paracentesis using a 30-gauge needle was performed in nine female Dutch-belted ...
    • Subretinal injection of preservative-free triamcinolone acetonide and supernatant vehicle in rabbits: an electron microscopy study 

      Maia, Mauricio [UNIFESP]; Penha, Fernando Marcondes [UNIFESP]; Farah, Michel Eid [UNIFESP]; Dib, Eduardo [UNIFESP]; Principe, Andre [UNIFESP]; Lima Filho, Acacio A. S. [UNIFESP]; Magalhaes, Octaviano [UNIFESP]; Freymueller, Edna [UNIFESP]; Rodrigues, Eduardo B. [UNIFESP] (Springer, 2008-03-01)
      Background To evaluate the effect of injections of benzyl alcohol (BA)-free triamcinolone acetonide (TA) solution (MTA-PF) and the supernatant vehicle of TA (STA) containing BA into the subretinal space of rabbit eyes.Methods ...
    • Técnica para injeção intravítrea de drogas no tratamento de doenças vítreorretinianas 

      Rodrigues, Eduardo Buchele [UNIFESP]; Maia, Maurício [UNIFESP]; Penha, Fernando Marcondes [UNIFESP]; Dib, Eduardo [UNIFESP]; Bordon, Arnaldo Furman [UNIFESP]; Magalhães Júnior, Octaviano [UNIFESP]; Farah, Michel Eid [UNIFESP] (Conselho Brasileiro de Oftalmologia, 2008-12-01)
      Intravitreal injections are the standard technique applied in the treatment of some vitreoretinal diseases. In this paper the technique and complications of intravitreal injections are presented. In summary, the procedure ...
    • Toxicological considerations for intravitreal drugs 

      Penha, Fernando M. [UNIFESP]; Rodrigues, Eduardo B. [UNIFESP]; Furlani, Bruno A. [UNIFESP]; Dib, Eduardo [UNIFESP]; Melo, Gustavo B. [UNIFESP]; Farah, Michel E. [UNIFESP] (Informa Healthcare, 2011-08-01)
      Introduction: Intravitreal injections are a very common procedure and are the most effective route of drug delivery to the retina. There are currently several drugs available and even more are in development; therefore, ...
    • The Use of Vital Dyes in Ocular Surgery 

      Rodrigues, Eduardo B. [UNIFESP]; Costa, Elaine F. [UNIFESP]; Penha, Fernando M. [UNIFESP]; Melo, Gustavo B. [UNIFESP]; Bottos, Juliana [UNIFESP]; Dib, Eduardo [UNIFESP]; Furlani, Bruno [UNIFESP]; Lima, Veronica C. [UNIFESP]; Maia, Mauricio [UNIFESP]; Meyer, Carsten H.; Hoefling-Lima, Ana Luisa [UNIFESP]; Farah, Michel E. [UNIFESP] (Elsevier B.V., 2009-09-01)
      Vital dyes have advanced diagnosis and surgical technique in various specialties, including oncology, gastroenterology, and ophthalmology. in ocular Surgery vital dyes are widely used in cataract and vitreoretinal surgery. ...
    • Vital Dyes and Light Sources for Chromovitrectomy: Comparative Assessment of Osmolarity, pH, and Spectrophotometry 

      Costa, Elaine de Paula Fiod [UNIFESP]; Rodrigues, Eduardo Buchele [UNIFESP]; Farah, Michel Eid [UNIFESP]; Dib, Eduardo [UNIFESP]; Penha, Fernando Marcondes [UNIFESP]; Magalhaes, Octaviano [UNIFESP]; Furlani, Bruno Albuquerque [UNIFESP]; Lima Filho, Acácio Alves de Souza [UNIFESP]; Miranda, Antonio de [UNIFESP]; Maia, Mauricio [UNIFESP] (Assoc Research Vision Ophthalmology Inc, 2009-01-01)
      PURPOSE. To investigate the in vitro pH, osmolarity, spectral, and photostability properties of nine vital dyes for vitreoretinal surgery.METHODS. Nine dyes-indocyanine green (ICG), trypan blue (TB), brilliant blue (BriB), ...