Browsing by Author "D'Almeida, Vania [UNIFESP]"

Now showing items 1-20 of 117

    • 24 bp duplication of CHIT1 gene and determinants of human chitotriosidase activity among participants of EPISONO, a population-based cross-sectional study, São Paulo, Brazil 

      Tamanaha, Priscila [UNIFESP]; D'Almeida, Vania [UNIFESP]; Calegare, Bruno F. A. [UNIFESP]; Tomita, Luciana Yuki [UNIFESP]; Bittencourt, Lia Rita A. [UNIFESP]; Tufik, Sergio [UNIFESP] (Elsevier B.V., 2013-08-01)
      Objectives: We investigated whether plasma chitotriosidase activity is related to Obstructive Sleep Apnea (OSA) conditions and is correlated with biochemical variables present in the EPISONO database. This is the first ...

    • ACE activity is modulated by the enzyme alpha-galactosidase A 

      Batista, Elice Carneiro; Carvalho, Luiz Roberto; Casarini, Dulce Elena [UNIFESP]; Carmona, Adriana Karaoglanovic; Santos, Edson Lucas dos; Silva, Elton Dias da; Santos, Robson Augusto dos; Nakaie, Clovis Ryuichi; Munoz Rojas, Maria Veronica; Oliveira, Suzana Macedo de; Bader, Michael; D'Almeida, Vania [UNIFESP]; Martins, Ana Maria [UNIFESP]; Souza, Kely de Picoly; Pesquero, Joao Bosco [UNIFESP] (Springer, 2011-01-01)
      Fabry disease is a multisystem X-linked disorder resulting from alpha-galactosidase A (alpha-GalA) gene mutations leading to the accumulation of globotriaosylceramide mainly in endothelium compromising heart, kidney, and ...

    • Acute benzodiazepine administration induces changes in homocysteine metabolism in young healthy volunteers 

      Pompeia, Sabine [UNIFESP]; Grego, Bruno H. C. [UNIFESP]; Pradella-Hallinan, Marcia [UNIFESP]; Hachul, Helena [UNIFESP]; Tufik, Sergio [UNIFESP]; D'Almeida, Vania [UNIFESP] (Elsevier B.V., 2009-08-31)
      Purpose: High cortisol plasma concentrations have been shown to be associated with increases in homocysteine levels. Here we studied whether decreases in cortisol concentration, induced by an acute oral dose of a benzodiazepine, ...

    • alpha-L-iduronidase gene-based therapy using the phiC31 system to treat mucopolysaccharidose type I mice 

      Stilhano, Roberta Sessa [UNIFESP]; Martin, Priscila Keiko Matsumoto [UNIFESP]; Melo, Suely Maymone de [UNIFESP]; Samoto, Vivian Yochiko [UNIFESP]; Peres, Giovani Bravin [UNIFESP]; Michelacci, Yara Maria [UNIFESP]; Silva, Flavia Helena da [UNIFESP]; Pereira, Vanessa Gonçalves [UNIFESP]; D'Almeida, Vania [UNIFESP]; Cruz, Adriana Taveira da [UNIFESP]; Jasiulionis, Miriam Galvonas [UNIFESP]; Han, Sang Won [UNIFESP] (Wiley-Blackwell, 2015-01-01)
      BackgroundMucopolysaccharidose type I (MPSI) is a lysosomal monogenic disease caused by mutations in the gene for - l-iduronidase (IDUA). MPSI patients need a constant supply of IDUA to alleviate progression of the disease. ...

    • alpha-Tocopherol induces hematopoietic stem/progenitor cell expansion and ERK1/2-mediated differentiation 

      Nogueira-Pedro, Amanda [UNIFESP]; Barbosa, Christiano M. V. [UNIFESP]; Segreto, Helena Regina Comodo [UNIFESP]; Lungato, Lisandro [UNIFESP]; D'Almeida, Vania [UNIFESP]; Moraes, Andrea Aparecida F. S. [UNIFESP]; Miranda, Antonio [UNIFESP]; Paredes-Gamero, Edgar Julian [UNIFESP]; Ferreira, Alice Teixeira [UNIFESP] (Federation Amer Soc Exp Biol, 2011-12-01)
      Tocopherols promote or inhibit growth in different cell types. in the hematopoietic system, the radioprotective property of tocopherols is thought to act through the expansion of primitive hematopoietic cells. However, the ...

    • Alterações centrais e periféricas relacionadas ao balanço energético de ratos submetidos ao exercício resistido e expostos ao decanoato de nandrolona 

      Pozzi, Renan [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2016-09-27)
      Resistance training (REx) and chronic supraphysiological use of anabolic androgenic steroids (AAS) modify neuroendocrine responses. However, the association of both is still unclear. Our aim was to evaluate the effects of ...

    • Analysis of male reproductive parameters in a murine model of mucopolysaccharidosis type I (MPS I) 

      Nascimento, Cinthia Castro do [UNIFESP]; Aguiar, Odair [UNIFESP]; D'Almeida, Vania [UNIFESP] (E-century Publishing Corp, 2014-01-01)
      Mucopolysaccharidosis (MPS) I is a lysosomal storage disorder (LSD) that is characterised by alpha-L-idu-ronidase (Idua) deficiency and continuous deposition of glycosaminoglycans (GAGs), which consequently interferes with ...

    • Análise biomecânica, morfológica e da resposta nociceptiva em modelo animal de Mucopolissacaridose tipo I 

      Ferreira, Nicole Yolanda [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2019-02-28)
      Mucopolysaccharidoses (MPS) are a group of inborn errors of metabolism (IEM), in which specific lysosomal enzymes that participate of glycosaminoglycan (GAG) degradation are deficient or inactive. Musculoskeletal impairment ...

    • Análise Do Ritmo De Atividade E Repouso E Do Perfil De Melatonina Em Pacientes Com Doença De Fabry 

      Vallim, Julia Ribeiro Da Silva [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2018-03-29)
      Introduction: Fabry’s disease is caused by a mutation in GLA gene, whose consequence is the accumulation of glycosphingolipids within the lysosomes. The classic symptomatology of the disease develops in the first decades ...

    • Análise morfofuncional de órgãos reprodutivos masculinos e investigação do comportamento sexual em modelo animal de mucopolissacaridose do Tipo I (MPS I) 

      Nascimento, Cinthia Castro do [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2018-03-29)
      Mucopolysaccharidosis Type I (MPS I) is a lysosomal storage disease caused by a mutation of IDUA gene. IDUA codes α-L-iduronidase, a lysosomal hydrolase that degrades heparan and dermatan sulfates, two types of glycosaminoglycans ...

    • Angiotensin I-converting enzyme (ACE) activity and expression in rat central nervous system after sleep deprivation 

      Visniauskas, Bruna [UNIFESP]; Oliveira, Vitor [UNIFESP]; Carmona, Adriana K. [UNIFESP]; D'Almeida, Vania [UNIFESP]; Melo, Robson L. de; Tufik, Sergio [UNIFESP]; Chagas, Jair R. [UNIFESP] (Walter de Gruyter & Co, 2011-04-01)
      Proteases are essential either for the release of neuropeptides from active or inactive proteins or for their inactivation. Neuropeptides have a fundamental role in sleep-wake cycle regulation and their actions are also ...

    • Avaliação clínico-nutricional e metabólica em mucopolissacaridoses. 

      Monteiro, Vaneisse Cristina Lima [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2014)
      A mucopolissacaridose (MPS) e um erro inato do metabolismo (EIM), caracterizado pela defiCiência de enzimas lisossomais envolvidas na degradacao dos glicosaminoglicanos (GAG), resultando em uma doenca com manifestacoes ...

    • Avaliação da ansiedade, estado de humor e sono e sua relação com o número de lesões em atletas de ginástica artística 

      Bezerra, Roberto Rodrigues (Universidade Federal de São Paulo, 2020-04-24)
      O objetivo do presente estudo foi comparar a relação entre os aspectos psicobiológicos (cronotipo, qualidade de sono, ansiedade e estado de humor) e lesões em atletas de ginástica artística. A amostra foi composta por 37 ...

    • Avaliação da relação entre ritmos biológicos e fisiologia dos lisossomos e sua participação em modelo de doença lisossômica 

      Oliveira, Ana Carolina Barris de [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2016-03-31)
      The clock system is responsible for the orchestration observed in several physiological, cellular and molecular processes. This regulation is controlled by a molecular machinery that allows the ideal synchronization of ...

    • The beneficial effects of strength exercise on hippocampal cell proliferation and apoptotic signaling is impaired by anabolic androgenic steroids 

      Novaes Gomes, Fabiano Guimaraes [UNIFESP]; Fernandes, Jansen [UNIFESP]; Campos, Diego Vannucci [UNIFESP]; Cassilhas, Ricardo Cardoso [UNIFESP]; Viana, Gustavo Monteiro [UNIFESP]; D'Almeida, Vania [UNIFESP]; Moraes Rego, Marta Karavisch de [UNIFESP]; Buainain, Pedro Ivo [UNIFESP]; Cavalheiro, Esper Abrao [UNIFESP]; Arida, Ricardo Mario [UNIFESP] (Elsevier B.V., 2014-12-01)
      Previous studies have shown that strength exercise improves memory and increases expression of a myriad of proteins involved on neuronal survival and synaptic plasticity in the hippocampus. Conversely, chronic exposure to ...

    • Beneficial effects of vitamin C and vitamin E on reserpine-induced oral dyskinesia in rats: Critical role of striatal catalase activity 

      Faria, Rulian Ricardo [UNIFESP]; Abilio, Vanessa Costhek [UNIFESP]; Grassl, Christian [UNIFESP]; Chinen, Cibele Cristina [UNIFESP]; Negrão, Luciana Takahashi Ribeiro [UNIFESP]; Castro, Juliana Pedroso Moraes Vilela de [UNIFESP]; Fukushiro, Daniela Fukue [UNIFESP]; Rodrigues, Marcelo Scarpari Dutra [UNIFESP]; Gomes, Patricia Helena Zanier [UNIFESP]; Registro, Sibele [UNIFESP]; Carvalho, Rita de Cassia [UNIFESP]; D'Almeida, Vania [UNIFESP]; Silva, Regina Helena [UNIFESP]; Ribeiro, Rosana de Alencar [UNIFESP]; Frussa-Filho, Roberto [UNIFESP] (Elsevier B.V., 2005-06-01)
      Oral dyskinesias are implicated in a series of neuropathologies and have been associated to an increase in oxidative stress. Several antioxidants, including vitamin E, decrease reserpine-induced oral clyskinesia (OD) in ...

    • Biochemical, biometrical and behavioral changes in male offspring of sleep-deprived mice 

      Aguilar Calegare, Bruno Frederico [UNIFESP]; Fernandes, Leandro [UNIFESP]; Tufik, Sergio [UNIFESP]; D'Almeida, Vania [UNIFESP] (Elsevier B.V., 2010-06-01)
      Epidemiological and experimental studies suggest a high prevalence of cognitive impairment and social behavior deficits in adolescents and adults that have experienced prenatal exposure to adverse conditions. This study ...

    • Brazilian reference values for MPS II screening in dried blood spots - A fluorimetric assay 

      Rezende, Marina Mastelaro [UNIFESP]; Mueller, Karen Barbosa [UNIFESP]; Pereira, Vanessa Goncalves [UNIFESP]; D'Almeida, Vania [UNIFESP] (Elsevier B.V., 2014-09-01)
      Objectives: Mucopolysaccharidosis II (MPS II), or Hunter Syndrome, is a lysosomal storage disorder that is caused by the deficiency or absence of iduronate-2-sulfatase (IDS) enzyme; in this disease, early diagnosis is ...

    • Cannabidiol Prevents Motor and Cognitive Impairments Induced by Reserpine in Rats 

      Peres, Fernanda Fiel [UNIFESP]; Leyin, Raquel [UNIFESP]; Suiama, Mayra Akimi [UNIFESP]; Diana, Mariana Cepollaro [UNIFESP]; Gouvea, Douglas Albuquerque [UNIFESP]; Almeida, Valeria [UNIFESP]; Santos, Camila Mauricio [UNIFESP]; Lungato, Lisandro [UNIFESP]; Zuardi, Antonio W.; Hallak, Jaime E. C.; Crippa, Jose A.; D'Almeida, Vania [UNIFESP]; Silva, Regina Helena da [UNIFESP]; Abilio, Vanessa Costhek [UNIFESP] (Frontiers Media Sa, 2016)
      Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that presents antipsychotic, anxiolytic, anti-inflammatory, and neuroprotective effects. In Parkinson's disease patients, CBD is able to attenuate ...

    • Caracterização de parâmetros reprodutivos em um modelo murino de mucopolissacaridose tipo I 

      Mendes, Ana Beatriz Barbosa [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2018-08-30)
      Mucopolysaccharidosis type I (MPS I) is a lysosomal storage disorder characterised by α-L-iduronidase (IDUA) deficiency. IDUA is responsible for the breakdown of glycosaminoglycans (GAGs), specifically dermatan sulphate ...