Now showing items 1-20 of 109

    • The action of prolyl-leucyl-glycinamide (PLG) on the nigrostriatal pathway of the rat 

      Pereira, João S.; Andrade, Luiz Augusto Franco de [UNIFESP]; Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Lima, J. Geraldo Camargo [UNIFESP]; Ferraz, Henrique B. (Academia Brasileira de Neurologia - ABNEURO, 1990-06-01)
      In order to study the nigrostriatal pathway, we obtained the rotatory behavior model in male Wistar rats by electrolytic lesion of the left lateral hypothalamic region. Animals thus lesioned displayed rotations toward the ...
    • Adaptação e correlação entre instrumentos neuropsicológicos para avaliação e acompanhamento da doença de Alzheimer em fases avançadas 

      Wajman, José Roberto [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2012)
      Objetivo: foi objetivo principal deste projeto o estudo da correlacao entre instrumentos especificos para avaliacao de pacientes com demencia da doenca de Alzheimer em fases avancadas no que diz respeito a sua cognicao ...
    • Adaptação transcultural da escala de avaliação de incapacidade em demência (Disability Assessment For Dementia - DAD) 

      Carthery-goulart, Maria Tereza; Areza-fegyveres, Renata; Schultz, Rodrigo R. [UNIFESP]; Okamoto, Ivan [UNIFESP]; Caramelli, Paulo; Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Nitrini, Ricardo (Academia Brasileira de Neurologia - ABNEURO, 2007-09-01)
      The original version of the Disability Assessment for Dementia (DAD) was translated into Portuguese and back translated to English. The divergences of translation were identified and discussed, resulting in a version that ...
    • Alterações de linguagem nas fases iniciais da doença de Alzheimer 

      Ortiz, Karin Zazo [UNIFESP]; Bertolucci, Paulo Henrique Ferreira [UNIFESP] (Academia Brasileira de Neurologia - ABNEURO, 2005-06-01)
      Alzheimer disease (AD) is usually associated with cognitive, language and behavioral impairments, which can get more and more serious as the disease progresses. The aim of this study is to verify language disorders in the ...
    • ALTERNATING PERIODIC LATERALIZED EPILEPTIFORM DISCHARGES (CEREBRAL BIGEMINY) 

      Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Silva, Ademir Baptista [UNIFESP] (Clinical Eeg, 1992-10-01)
    • Amnesia global transitória: estudo de 26 casos 

      Zukerman, Eliova [UNIFESP]; Andrade, Luiz Augusto Franco de [UNIFESP]; Bertolucci, Paulo Henrique Ferreira [UNIFESP] (Academia Brasileira de Neurologia - ABNEURO, 1985-03-01)
      The clinical picture and investigation of 26 patients (16 males and 10 females) with diagnosis of transient global amnesia (TGA) are reported. Age ranged from 51 to 78 years at the time of TGA, which occurred more often ...
    • Análise Do Padrão Articulatório Na Tarefa De Fluência Verbal Frutas No Comprometimento Cognitivo Leve, Na Demência De Alzheimer Leve E Moderado 

      Giacominelli, Carla [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2017-11-17)
      The semantic verbal fluency task as a neuropsychological assessment, is widely used in the clinical practice of Alzheimer's Disease (AD) and involves the subject generate during 60s to generate the highest number of words ...
    • Another locus for autosomal dominant late onset Alzheimers disease in Brazilian families? 

      Nishimura, A. L.; Oliveira, JRM; Brito-Marques, P. R.; Nitrini, R.; Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Okamoto, Ivan Hideyo [UNIFESP]; Zatz, M. (Univ Chicago Press, 2002-10-01)
    • Apolipoprotein A-V gene polymorphism -1131T > C and Alzheimer's disease 

      Barbosa, Fabio Augusto Freiria; Labio, Roger Willian de; Rigolin, Valdeci Oliveira Santos [UNIFESP]; Minett, Thaís Soares Cianciarullo [UNIFESP]; Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Smith, Marilia de Arruda Cardoso [UNIFESP]; Payão, Spencer Luiz Marques [UNIFESP] (Ios Press, 2006-12-01)
      Alzheimer's disease (AD) is the most common neurodegenerative disorder in the elderly and is also considered a progeroid genetic syndrome. The etiology of AD is complex and the mechanisms underlying its pathophysiology ...
    • Apolipoprotein E4 allele and ribosomal genes in Alzheimer's disease 

      Tavares, W. M.; Speranca, M. A.; Labio, Roger Willian de; Peres, Clovis de Araujo [UNIFESP]; Okamoto, Ivan Hideyo [UNIFESP]; Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Smith, Marilia de Arruda Cardoso [UNIFESP]; Payão, Spencer Luiz Marques [UNIFESP] (Ios Press, 2004-08-01)
      Ribosomal genes are involved in cellular transcription, translation and gene expression modulation process. An association between 28S/18S rRNA ratio levels with apoptosis and aging has been reported. Moulder et al. [22] ...
    • Applicability of the abbreviated neuropsychologic battery (NEUROPSI) in Alzheimer disease patients 

      Abrisqueta-Gomez, Jacqueline [UNIFESP]; Ostrosky-Solis, Feggy; Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Bueno, Orlando Francisco Amodeo [UNIFESP] (Lippincott Williams & Wilkins, 2008-01-01)
      NEUROPSI is a brief neuropsychologic battery developed to briefly assess a wide spectrum of cognitive functions. The aim of this study was to examine the applicability of a Portuguese version of this battery and verify the ...
    • Applicability of the CERAD neuropsychological battery to Brazilian elderly 

      Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Okamoto, Ivan Hideyo [UNIFESP]; Brucki, Sonia Maria Dozzi [UNIFESP]; Siviero, Marilena Occhini [UNIFESP]; Toniolo Neto, João [UNIFESP]; Ramos, Luiz Roberto [UNIFESP] (Academia Brasileira de Neurologia - ABNEURO, 2001-09-01)
      There is a limited choice of psychometric tests for Portuguese speaking people which have been evaluated in well defined groups. A Portuguese version of CERAD neuropsychological battery was applied to a control group of ...
    • Apraxia da marcha em indivíduos com doença de Alzheimer leve e moderada 

      Pereira, Fernando Vieira [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2006)
      OBJETIVOS: Correlacionar a presença de distúrbios apráxicos da marcha com o comprometimento cognitivo e a severidade da doença de Alzheimer, além de também verificar os aspectos de balance e independência funcional dos ...
    • Apresentação e aplicabilidade da versão brasileira da MoCA (Montreal Cognitive Assessment )para rastreio de Comprometimento Cognitivo Leve 

      Sarmento, Ana Luisa Rosas [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2009-11-25)
      Introdução: No último século, a expectativa média da população mundial aumentou significantemente com os adventos tecnológicos e científicos nas diferentes áreas, incluindo a saúde.Com isso, mais pessoas têm sido acometidas ...
    • Aspectos cocnitivos da doença de Alzheimer no teste do relógio: avaliação de amostra da população brasileira 

      Okamoto, Ivan Hideyo [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2001)
      OBJETIVOS: Avaliar o desempenho cognitivo de pacientes com doença de Alzheimer (DA), demência por corpúsculos de Lewy (DL) e Declínio Cognitivo Leve (DCL) no Teste do Relógio(TR), comparados com populaçao idosa normal ...
    • Assessment of risk factors for earlier onset of sporadic Alzheimer's disease dementia 

      Oliveira, Fabricio Ferreira de [UNIFESP]; Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Chen, Elizabeth Suchi [UNIFESP]; Smith, Marilia de Arruda Cardoso [UNIFESP] (Medknow Publications & Media Pvt Ltd, 2014-11-01)
      Background: Pharmacological treatment has mild effects for patients with Alzheimer's disease dementia (AD); therefore, the search for modifiable risk factors is an important challenge. Though risk factors for AD are widely ...
    • Assessment of sleep satisfaction in patients with dementia due to Alzheimer's disease 

      Oliveira, Fabricio Ferreira de [UNIFESP]; Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Chen, Elizabeth Suchi [UNIFESP]; Smith, Marilia de Arruda Cardoso [UNIFESP] (Elsevier B.V., 2014-12-01)
      Sleep length and architecture are potential markers of progressive cognitive impairment, while neuropsychiatric symptoms and APOE4- haplotypes have been associated with more sleep complaints in patients with dementia due ...
    • Association analysis between K and-116A variants of butyrylcholinesterase and Alzheimer's disease in a Brazilian population 

      Simao-Silva, Daiane Priscila; Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Labio, Roger William de; Payão, Spencer Luiz Marques [UNIFESP]; Furtado-Alle, Lupe; Rodrigues Souza, Ricardo Lehtonen (Elsevier B.V., 2013-03-25)
      In Alzheimer's disease (AD) a reduction in acetylcholinesterase (AChE) and an increase in butyrylcholinesterase (BChE) activity are observed. K variant (539T) is the most common variant of the BCHE gene and, although ...
    • Association of interleukin 1 beta polymorphisms and haplotypes with Alzheimer's disease 

      Payão, Spencer Luiz Marques [UNIFESP]; Gonçalves, Gisela Moraes; Lábio, Roger Willian de; Horiguchi, Lie; Mizumoto, Igor; Rasmussen, Lucas Trevizani [UNIFESP]; Pinhel, Marcela Augusta de Souza; Souza, Dorotéia Rossi Silva; Bechara, Marcelo Dib; Chen, Elizabeth Suchi [UNIFESP]; Mazzotti, Diego Robles [UNIFESP]; Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Smith, Marilia de Arruda Cardoso [UNIFESP] (Elsevier B.V., 2012-06-15)
      Our study aimed to associate IL-1 beta and IL-1RN polyrnorphisms with AD disease in comparison with elderly control group from São Paulo - Brazil. We genotyped 199 Alzheimer's disease (AD) patients, 165 elderly control and ...
    • Attention impairment associated with relapsing-remitting multiple sclerosis patients with mild incapacity 

      Balsimelli, Silvia; Mendes, Maria Fernanda; Bertolucci, Paulo Henrique Ferreira [UNIFESP]; Tilbery, Charles Peter (Academia Brasileira de Neurologia - ABNEURO, 2007-06-01)
      Neuropsychological studies have consistently reported cognitive dysfunctions associated with multiple sclerosis. One-hundred fifteen subjects with relapsing-remitting multiple sclerosis (RRMS) were compared with forty ...