Now showing items 21-40 of 116

    • Different patterns of epileptiform-like activity are generated in the sclerotic hippocampus from patients with drug-resistant temporal lobe epilepsy 

      Reyes-Garcia, Selvin Z. [UNIFESP]; Scorza, Carla Alessandra [UNIFESP]; Araujo, Noemi S. [UNIFESP]; Ortiz-Villatoro, Nancy N. [UNIFESP]; Jardim, Anaclara Prada [UNIFESP]; Centeno, Ricardo Silva [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP]; Faber, Jean [UNIFESP]; Cavalheiro, Esper Abrão [UNIFESP] (Nature Publishing Group, 2018)
      Human hippocampal slice preparations from patients with temporal lobe epilepsy (TLE) associated with hippocampal sclerosis (HS) are excellent material for the characterization of epileptiform-like activity. However, it is ...

    • Dysmorphic neurons in patients with temporal lobe epilepsy 

      Silva, A. V. da; Houzel, J. C.; Yacubian, Elza Márcia Targas [UNIFESP]; Carrete, H.; Sakamoto, A. C.; Priel, M. R.; Martins, H. H.; Oliveira, I; Garzon, E.; Stavale, J. N.; Centeno, R. D.; Machado, H.; Cavalheiro, E. A. (Elsevier B.V., 2006-02-09)
      We studied morphologic characteristics of dysmorphic neurons in the hippocampus of seven patients with medically intractable TLE and compare histological, clinical, and imaging features with ten TLE patients with classical ...

    • Early destructive lesions in the developing brain: clinical and electrographic correlates 

      Low, Cristiane [UNIFESP]; Garzon, Eliana [UNIFESP]; Carrete Junior, Henrique [UNIFESP]; Vilanova, Luiz Celso Pereira [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP]; Sakamoto, Américo Ceiki [UNIFESP] (Academia Brasileira de Neurologia - ABNEURO, 2007-06-01)
      OBJECTIVE: Early brain insults can cause cavitary lesions including porencephaly (POR) and multicystic encephalopathy (MCE). The objective of this study was to investigate clinical and electrographic correlates associated ...

    • EEG recording after sleep deprivation in a series of patients with juvenile myoclonic epilepsy 

      Sousa, Nise Alessandra de Carvalho [UNIFESP]; Sousa, Patrícia da Silva [UNIFESP]; Garzon, Eliana [UNIFESP]; Sakamoto, Américo Ceiki [UNIFESP]; Braga, Nádia I.o. [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP] (Academia Brasileira de Neurologia - ABNEURO, 2005-06-01)
      Seizures in Juvenile Myoclonic Epilepsy (JME) are dependent on the sleep-wake cycle and precipitant factors, among which sleep deprivation (SD) is one of the most important. Still an under diagnosed syndrome, misinterpretation ...

    • Efeitos psiquiátricos e comportamentais das drogas antiepilépticas e sua ação como moduladores de humor 

      Araujo Filho, Gerardo Maria de [UNIFESP]; Mazetto, Lenon [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP] (Liga Brasileira de Epilepsia (LBE), 2011-01-01)
      INTRODUCTION: The association between epilepsy, psychiatric disorders (PD) and antiepileptic drugs (AED) is among the most frequent and important aspects of epileptology. According to most recent data in literature, AED ...

    • Employment and quality of life in mesial temporal lobe epilepsy with hippocampal sclerosis: is there a change after surgical treatment? 

      Alonso, Neide Barreira [UNIFESP]; Azevedo, Auro Mauro [UNIFESP]; Centeno, Ricardo Silva [UNIFESP]; Guilhoto, Laura Maria de Figueiredo Ferreira [UNIFESP]; Caboclo, Luís Otávio Sales Ferreira [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP] (Liga Brasileira de Epilepsia (LBE), 2009-06-01)
      PURPOSE: The aim of this study was to evaluate in patients with mesial temporal lobe epilepsy (MTLE) with hippocampal sclerosis (HS): (1) employment patterns before and three years after epilepsy surgery and their impact ...

    • Epilepsia mioclonica juvenil 

      Yacubian, Elza Márcia Targas [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2008)
    • Espectroscopia por ressonância magnética de prótons em epilepsia mioclônica juvenil sugere o comprometimento de uma rede neuronal específica 

      Lin, Katia [UNIFESP]; Carrete Junior, Henrique [UNIFESP]; Lin, Jaime [UNIFESP]; Peruchi, M.m. [UNIFESP]; Araujo Filho, Gerardo Maria de [UNIFESP]; Pascalicchio, T.f. [UNIFESP]; Guaranha, Mirian Salvadori Bittar [UNIFESP]; Guilhoto, Laura Maria de Figueiredo Ferreira [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP] (Liga Brasileira de Epilepsia (LBE), 2008-09-01)
      OBJECTIVES: The neuroanatomical basis and the neurochemical abnormalities that underlay juvenile myoclonic epilepsy (JME) are not fully defined. While the thalamus plays a central role in synchronization of widespread ...

    • Estereoeletroencefalografia na era da cirurgia guiada por imagem 

      Centeno, Ricardo Silva [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP]; Caboclo, Luís Otávio Sales Ferreira [UNIFESP]; Carrete Junior, Henrique [UNIFESP]; Hamad, Ana Paula Andrade [UNIFESP]; Ferraz, Fernando Antônio Patriani [UNIFESP]; Cavalheiro, Sergio [UNIFESP] (Liga Brasileira de Epilepsia (LBE), 2009-12-01)
      INTRODUCTION: The stereoelectroencephalography (SEEG), introduced by Talairach in 50', is an invasive method of tridimensional analysis of epileptogenic zone based on the intracranial placement of depth electrodes (DE). ...

    • Estimulação fótica: padronização do método de acordo com o consenso europeu 

      Britto, Fernanda dos Santos [UNIFESP]; Santana, Maria Teresa Castilho Garcia de [UNIFESP]; Albuquerque, Hercília Rosa Xavier de [UNIFESP]; Uchida, Carina Gonçalves Pedroso [UNIFESP]; Souza, Larissa Teles de [UNIFESP]; Caboclo, Luís Otávio Sales Ferreira [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP] (Liga Brasileira de Epilepsia (LBE), 2008-06-01)
      INTRODUCTION: Although intermittent photic stimulation (IPS) is a widespread and routinely used procedure in EEG laboratories, only relatively recently has a standardization of the IPS method been proposed. IPS is an ...

    • Estudo anátomo-funcional por ressonância magnética em pacientes com epilepsia mioclônica juvenil 

      Lin, Katia [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2009-06-24)
      Purpose: The neuroanatomical basis and the neurochemical abnormalities that underlie juvenile myoclonic epilepsy (JME) are not fully understood. While the thalamus plays a central role in synchronization of widespread ...

    • Estudo da associação entre transtornos de personalidade e alterações de neuroimagem em pacientes com epilepsia mioclônica juvenil 

      Araujo Filho, Gerardo Maria de [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2009-04-29)
      Purpose: Studies involving juvenile myoclonic epilepsy (JME) patients have demonstrated an elevated prevalence of cluster B personality disorders (PD) characterized as emotional instability and immaturity, unsteadiness, ...

    • Estudo da prevalência de transtornos em pacientes com epilepsia mioclônica juvenil 

      Araujo Filho, Gerardo Maria de [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2007)
      Objetivos: Este estudo visa determinar a frequencia de transtornos psiquiatricos em pacientes com epilepsia mioclonica juvenil (EMJ) e sua relacao com aspectos clinicos da referida sindrome epileptica. Metodos: Cem pacientes ...

    • Estudo vídeo-eletroencefalográfico do efeito de fatores precipitantes em pacientes com epilepsia mioclonica juvenil 

      Sousa, Patrícia da Silva [UNIFESP] (Universidade Federal de São Paulo (UNIFESP), 2006)
      As crises epilépticas podem ser precipitadas por vários fatores, endógenos ou exógenos. O conhecimento de fatores precipitantes e inibitórios de crises pode auxiliar o tratamento e propiciar ao ...

    • Expression and activity of thimet oligopeptidase (TOP) are modified in the hippocampus of subjects with temporal lobe epilepsy (TLE) 

      Rodrigues Simoes, Priscila Santos [UNIFESP]; Visniauskas, Bruna [UNIFESP]; Perosa, Sandra Regina [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP]; Centeno, Ricardo [UNIFESP]; Canzian, Mauro; Lopes-Cendes, Iscia; Maurer Morelli, Claudia Vianna; Carrete, Henrique [UNIFESP]; Cavalheiro, Esper Abrão [UNIFESP]; Tufik, Sergio [UNIFESP]; Chagas, Jair Ribeiro [UNIFESP]; Naffah-Mazzacoratti, Maria da Graca [UNIFESP] (Wiley-Blackwell, 2014-05-01)
      ObjectiveThimet oligopeptidase (TOP) is a metalloprotease that has been associated with peptide processing in several nervous system structures, and its substrates include several peptides such as bradykinin, amyloid beta ...

    • EXTRATEMPORAL INVOLVEMENT IN TEMPORAL LOBE EPILEPSY WITH MESIAL TEMPORAL SCLEROSIS - A VBM STUDY 

      Santana, M. [UNIFESP]; Silva, H. [UNIFESP]; Guimaraes, M. [UNIFESP]; Bussoletti, R. [UNIFESP]; Caboclo, Luís Otávio Sales Ferreira [UNIFESP]; Centeno, Ricardo Silva [UNIFESP]; Carrete Junior, Henrique [UNIFESP]; Jackowski, Andrea Parolin [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP] (Wiley-Blackwell, 2009-10-01)
    • Facial paresis in patients with mesial temporal lobe epilepsy: An important lateralizing though under-recognized focal neurological sign 

      Lin, Katia [UNIFESP]; Carrete Junior, Henrique [UNIFESP]; Lin, Jaime; Caboclo, Luís Otávio Sales Ferreira [UNIFESP]; Oliveira, Pedro Alessandro Leite de [UNIFESP]; Sakamoto, Américo Ceiki [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP] (Blackwell Publishing, 2006-01-01)
    • Facial paresis in patients with mesial temporal sclerosis: Clinical and quantitative MRI-based evidence of widespread disease 

      Lin, Katia [UNIFESP]; Carrete Junior, Henrique [UNIFESP]; Lin, Jaime [UNIFESP]; Leite de Oliveira, Pedro Alessandro; Caboclo, Luis Otávio Sales Ferreira [UNIFESP]; Sakamoto, Américo Ceiki [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP] (Blackwell Publishing, 2007-08-01)
      Purpose: To assess the frequency and significance of facial paresis (FP) in a well-defined cohort of mesial temporal lobe epilepsy (MTLE) patients.Methods: One hundred consecutive patients with MRI findings consistent with ...

    • Fatores determinantes da viabilidade neuronal em fatias hipocampais de pacientes com epilepsia do lobo temporal mesial 

      Silva, Alexandre Valotta da [UNIFESP]; Silva, André César da [UNIFESP]; Carrete Junior, Henrique [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP]; Priel, Margareth Rose [UNIFESP]; Silva, Julieta Gonçalves [UNIFESP]; Centeno, Ricardo Silva [UNIFESP]; Cavalheiro, Esper Abrão [UNIFESP] (Liga Brasileira de Epilepsia (LBE), 2006-09-01)
    • Fusos extremos na era da ressonância magnética: características clínicas, eletrográficas e de neuroimagem 

      Maia, Maria Goretti Lima [UNIFESP]; Caboclo, Luís Otávio Sales Ferreira [UNIFESP]; Carrete Junior, Henrique [UNIFESP]; Garzon, Eliana [UNIFESP]; Sakamoto, Américo Ceiki [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP] (Liga Brasileira de Epilepsia (LBE), 2005-12-01)
      OBJECTIVES: Extreme spindles were described by Gibbs and Gibbs in 1962. They are typically observed in children younger than five years, occurring in 0.05% of normal children and in up to 5 to 18% of children with mental ...