Now showing items 1-10 of 16

    • Acute crack cocaine exposure induces genetic damage in multiple organs of rats 

      Moretti, Eduardo Gregolin [UNIFESP]; Yujra, Veronica Quispe [UNIFESP]; Claudio, Samuel Rangel [UNIFESP]; Silva, Marcelo Jose Dias; Vilegas, Wagner; Pereira, Camilo Dias Seabra [UNIFESP]; De Oliveira, Flavia [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP] (Springer Heidelberg, 2016)
      Crack cocaine is a very toxic product derived from cocaine. The aim of this study was to evaluate genetic damage in multiple organs of rats following acute exposure to crack cocaine. A total of 20 Wistar rats were distributed ...
    • Análise da citotoxicidade e genotoxicidade do crack empregando o organismo-teste Perna perna 

      Ortega, Andressa dos Santos Barbosa [UNIFESP] (Universidade Federal de São Paulo, 2018-04-19)
      Crack cocaine is the main by-product of cocaine, being considered an epidemic drug in urban areas. Cocaine has been a target of recent studies, since its presence has been identified in aquatic matrices in different ...
    • Anhydroecgonine methyl ester, a cocaine pyrolysis product, may contribute to cocaine behavioral sensitization 

      Tamborelli Garcia, Raphael Caio [UNIFESP]; Torres, Larissa Helena; Balestrin, Natalia Trigo; Andrioli, Tatiana Costa; Florio, Jorge Camilo; Rodrigues de Oliveira, Carolina Dizioli; da Costa, Jose Luiz; Yonamine, Mauricio; Lopes Sandoval, Maria Regina; Camarini, Rosana; Marcourakis, Tania (Elsevier Ireland Ltd, 2017)
      Crack cocaine has a high potential to induce cocaine addiction and its smoke contains cocaine's pyrolysis product anhydroecgonine methyl ester (AEME), a partial agonist at M-1- and M-3-muscarinic acetylcholine receptor and ...
    • Causes of death among crack cocaine users 

      Ribeiro, Marcelo [UNIFESP]; Dunn, John [UNIFESP]; Sesso, Ricardo de Castro Cintra [UNIFESP]; Dias, Andréa Costa [UNIFESP]; Laranjeira, Ronaldo [UNIFESP] (Associação Brasileira de Psiquiatria - ABP, 2006-09-01)
      OBJECTIVE: The study accompanied 131 crack-cocaine users over a 5-year period, and examined mortality patterns, as well as the causes of death among them. METHOD: All patients admitted to a detoxification unit in São Paulo ...
    • Consumo de crack a partir das perspectivas de gênero e vulnerabilidade: uma revisão sobre o fenômeno 

      Ramiro, Fernanda de Souza; Padovani, Ricardo da Costa [UNIFESP]; Tucci, Adriana Marcassa [UNIFESP] (Centro Brasileiro de Estudos de Saúde, 2014-04-01)
      The complexity of crack consumption has generated great challenges for managers. The objective of this study was to analyze, based on a ten-year literature review, gender issues and vulnerability conditions associated with ...
    • Crack cocaine users views regarding treatment with contingency management in Brazil 

      Miguel, Andre Q. C. [UNIFESP]; Madruga, Clarice S. [UNIFESP]; Simoes, Viviane [UNIFESP]; Yamauchi, Rodolfo [UNIFESP]; da Silva, Claudio J. [UNIFESP]; Abdalla, Renata R. [UNIFESP]; McDonell, Michael; McPherson, Sterling; Roll, John M.; Mari, Jair J. [UNIFESP]; Laranjeira, Ronaldo R. [UNIFESP] (Biomed Central Ltd, 2018)
      Background: Contingency management ( CM) has recently shown efficacy in promoting abstinence and retention in treatment among crack cocaine users in Brazil. However, partially because of unawareness and resistance among ...
    • Crack na cidade de São Paulo: acessibilidade, estratégias de mercado e formas de uso 

      Oliveira, Lúcio Garcia de [UNIFESP]; Nappo, Solange Aparecida [UNIFESP] (Faculdade de Medicina da Universidade de São Paulo, 2008-01-01)
      BACKGROUND: In Brazil, survey data have pointed to an increase in crack cocaine lifetime use, possibly due to changes on its accessibility, market strategies and ways of use. OBJECTIVE: To identify such issues in the crack ...
    • Desenvolvimento de entrevista estruturada para avaliar consumo de cocaína e comportamentos de risco 

      Dunn, John [UNIFESP]; Laranjeira, Ronaldo [UNIFESP] (Associação Brasileira de Psiquiatria - ABP, 2000-03-01)
      OBJECTIVE: To create a culturally-adjusted structured interview protocol in Portuguese to evaluate the drug history and HIV risk behaviors of cocaine users in Brazil. METHOD: A review of the literature provided a hidden ...
    • Exposure to crack cocaine causes adverse effects on marine mussels Perna perna 

      Maranho, Luciane Alves [UNIFESP]; Fontes, Mayana Karoline [UNIFESP]; Kamimura, A. S. S.; Nobre, Caio Rodrigues; Moreno, Beatriz Barbosa [UNIFESP]; Pusceddu, Fabio Hermes; Cortez, Fernando Sanzi; Lebre, Daniel T.; Marques, Joyce Rodrigues; Abessa, Denis Moledo de Souza; Ribeiro, Daniel Araki [UNIFESP]; Pereira, Camilo Dias Seabra [UNIFESP] (Pergamon-Elsevier Science Ltd, 2017)
      Our study aimed to evaluate crack cocaine effects in different life stages of the marine mussel Perna perm. For this purpose, fertilization rate, embryo-larval development, lysosomal membrane stability and DNA strand breaks ...
    • Fatores associados a perfusão cerebral anormal em dependentes de cocaína 

      Silveira, Dartiu Xavier da [UNIFESP]; Fernandes, Marcelo [UNIFESP]; Barbieri, Antonio [UNIFESP]; Labigalini, Eliseu [UNIFESP]; Silveira, Evelyn D [UNIFESP] (Associação Brasileira de Psiquiatria - ABP, 2001-03-01)
      OBJECTIVE: To evaluate the relationship between the pattern of cocaine use and cerebral perfusion among cocaine addicts. METHOD: A sample of 30 cocaine addicts was studied using 99 m-Tc-HMPAO SPECT (single photon emission ...