Navegando por Palavras-chave "weight"

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    Effects of growth hormone on body proportions in Turner syndrome compared with non-treated patients and normal women
    (Editrice Kurtis S R L, 2010-11-01) Baldin, A. D.; Fabbri, Tatiana [UNIFESP]; Siviero-Miachon, A. A. [UNIFESP]; Spinola-Castro, A. M. [UNIFESP]; Lemos-Marini, S. H. V.; Baptista, M. T. M.; D'Souza-Li, L. F. R.; Maciel-Guerra, A. T.; Guerra-Junior, G.; Universidade Estadual de Campinas (UNICAMP); Universidade Federal de São Paulo (UNIFESP)
    Background: the majority of anthropometric assessments in Turner syndrome (TS) patients has focused on height. AIM: To analyze body proportions in young adult TS patients either treated or not treated with rhGH, and to compare them with a group of age-matched healthy women. Subjects and methods: Standing height, sitting height, weight, foot and leg lengths, arm span, head circumference, biliac and bi-acromial diameters were measured in 52 non-treated TS patients, 30 treated with rhGH and 133 healthy women. Results: Age at the start of rhGH therapy varied from 7.8 to 15.1 yr (10.0 +/- 1.3 yr), the duration of treatment from 2.8 to 8.2 yr (3.7 +/- 1.5 yr) and the mean recombinant human GH (rhGH) dose was 0.42 mg/kg/week (from 0.32 to 0.50 mg/kg/week). Non-treated patients did not show any difference in anthropometric variables when compared with the treated ones, except for hand length (p=0.02) and height (p=0.05), which were increased in the treated group. All anthropometric variables, except head circumference, were different when comparing TS patients (either treated or not) with age-matched healthy women. Conclusion: Brazilian TS patients either treated or not with rhGH showed almost no differences in terms of their body proportions. This result is probably due to the late age at the start of treatment, and/or the short period of rhGH administration. Hand length was different between the groups, showing the importance of including the extremities in body proportion assessment during rhGH treatment of TS patients. (J. Endocrinol. Invest. 33: 691-695, 2010) (C) 2010, Editrice Kurtis
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    HDL cholesterol levels and weight are the main determinants of subclinical atherosclerosis in the young with type 1 diabetes and suitable glycaemic control
    (Sage Publications Ltd, 2014-03-01) Pinto, Camila S. [UNIFESP]; Lana, Janaina M. [UNIFESP]; Gabbay, Monica Andrade Lima [UNIFESP]; Sa, Joao R. de [UNIFESP]; Dib, Sergio A. [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    The aim of this study was to evaluate subclinical atherosclerosis and related factors in young type 1 diabetes (T1D) patients and healthy peers. Carotid intima-media thickness (cIMT) and anthropometric/laboratorial data were obtained for 83 T1D patients (mean age 19.5 +/- 4.0 years, disease duration 9.8 +/- 4.8 years) and for 36 matched healthy subjects. Considering all the participants as one group, male sex (p = 0.008), weight (p = 0.016) and T1D (p < 0.001) were positively associated with a higher cIMT. High-density lipoprotein (HDL) (p = 0.036) was negatively associated with cIMT in T1D. in the male T1D patients, HDL <= 47.5 mg/dL had a sensitivity of 87.5% and specificity of 57% (p = 0.035) in detecting those belonging to a higher cIMT tercile. in conclusion, weight and T1D were associated with increased cIMT. HDL levels <= 47.5 mg/dL were related to a higher cIMT in male T1D patients.
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    Indicadores de desempenho em rebanho da raça Holandesa: curvas de crescimento e altura, características reprodutivas, produtivas e parâmetros genéticos
    (Universidade Federal de Minas Gerais, Escola de Veterinária, 2004-02-01) Val, J.e. [UNIFESP]; Freitas, M.a.r. [UNIFESP]; Oliveira, H.n.; Cardoso, V.l.; Machado, P.f.; Paneto, J.c.c. [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade Estadual Paulista (UNESP); Instituto de Zootecnia; Universidade de São Paulo (USP)
    Data on weight, height, productive and reproductive performance of 1,272 Holstein heifers, born from 1990 to 1998, were used to evaluate the growth and height patterns of these females from birth to first calving, and the following traits: weight at first calving (PP), age at first calving (IP), milk production in the first lactation (PL) and first calving interval (IEP), and to estimate genetic parameters of these traits. The von Bertalanffy fitted models were: Yi=802.10 (1-0.630EXP (-0.0022t)) for weight, and Yi=1.40 (1-0.208EXP (-0.0038t)) for height. The average performance of heifers were: height 140cm, weight 602kg and 27 month of age at first calving. The total milk yield was 8,026kg and first IEP was 420 days. The (co)variance components estimates were obtained by a derivative-free algorithm with the DFREML. The estimates of heritabilities were 0.31, 0.35, 0.34, respectively for PP, IP and PL, and 0.10 for IEP. The genetic correlations estimates between PP and PL, PL and IP and IEP and PL were low. The correlation between IEP and PP was 0.49 and between IEP and IP was, -0.69, sugesting an antagonism between the two last traits.
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    Inspiratory Flow Limitation in a Normal Population of Adults in São Paulo, Brazil
    (Amer Acad Sleep Medicine, 2013-11-01) Palombini, Luciana de Oliveira [UNIFESP]; Tufik, Sergio [UNIFESP]; Rapoport, David M.; Ayappa, Indu A.; Guilleminault, Christian; Godoy, Luciana Ballester Mello de [UNIFESP]; Castro, Laura de Siqueira [UNIFESP]; Bittencourt, Lia Rita Azeredo[UNIFESP]; Universidade Federal de São Paulo (UNIFESP); NYU; Stanford Univ
    Study Objectives: Inspiratory flow limitation (IFL) during sleep occurs when airflow remains constant despite an increase in respiratory effort. This respiratory event has been recognized as an important parameter for identifying sleep breathing disorders. the purpose of this study was to investigate how much IFL normal individuals can present during sleep.Design: Cross-sectional study derived from a general population sample.Setting: A normal asymptomatic sample derived from the epidemiological cohort of São Paulo.Patients and Participants: This study was derived from a general population study involving questionnaires and nocturnal polysomnography of 1,042 individuals. A subgroup defined as a nonsymptomatic healthy group was used as the normal group.Interventions: N/A.Measurements and Results: All participants answered several questionnaires and underwent full nocturnal polysomnography. IFL was manually scored, and the percentage of IFL of total sleep time was considered for final analysis. the distribution of the percentage of IFL was analyzed, and associated factors (age, sex, and body mass index) were calculated. There were 95% of normal individuals who exhibited IFL during less than 30% of the total sleep time. Body mass index was positively associated with IFL.Conclusions: Inspiratory flow limitation can be observed in the polysomnography of normal individuals, with an influence of body weight on percentage of inspiratory flow limitation. However, only 5% of asymptomatic individuals will have more than 30% of total sleep time with inspiratory flow limitation. This suggests that only levels of inspiratory flow limitation > 30% be considered in the process of diagnosing obstructive sleep apnea in the absence of an apnea-hypopnea index > 5 and that < 30% of inspiratory flow limitation may be a normal finding in many patients.