Navegando por Palavras-chave "poliomyelitis"
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- ItemAcesso aberto (Open Access)Circadian variation of fatigue in both patients with paralytic poliomyelitis and post-polio syndrome(Academia Brasileira de Neurologia - ABNEURO, 2013-07-01) Viana, Celiana Figueiredo [UNIFESP]; Pradella-Hallinan, Márcia Lurdes de Cássia [UNIFESP]; Quadros, Abrahão Augusto Juviniano [UNIFESP]; Marin, Luis Fabiano [UNIFESP]; Oliveira, Acary Souza Bulle [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Objective It was to evaluate the degree of fatigue in patients with paralytic poliomyelitis (PP) and with post-polio syndrome (PPS), and correlate it with parameters of sleep and the circadian cycle. Methods Thirty patients, 17 female (56.7%), participated in the study: they answered the Revised Piper Fatigue Scale and performed a nocturnal polysomnographic study. Eleven had PP (mean age±standard deviation of 47.9±6.4 years), and 19 had PPS (mean age±standard deviation of 46.4±5.6 years). Results Our study showed that fatigue was worse in the afternoon in the PP Group and had a progressive increase throughout the day in the PPS Group. We also observed compromised quality of sleep in both groups, but no statically significant difference was found in the sleep parameters measured by polysomnography. Conclusion Fatigue has a well-defined circadian variation, especially in PPS Group. Poor sleep quality is associated with fatigue and, therefore, sleep disturbances should be evaluated and treated in this group of PPS.
- ItemAcesso aberto (Open Access)Frequency and clinical manifestations of post-poliomyelitis syndrome in a brazilian tertiary care center(Academia Brasileira de Neurologia - ABNEURO, 2012-08-01) Quadros, Abrahão Augusto Juviniano [UNIFESP]; Conde, Mônica Tilli Reis Pessoa; Marin, Luis Fabiano [UNIFESP]; Silva, Helga Cristina Almeida da [UNIFESP]; Silva, Tatiana Mesquita e [UNIFESP]; Paula, Maria Bernadete Eduardo de; Pereira, Roberto Dias Batista [UNIFESP]; Ramos, Paulo Eduardo [UNIFESP]; Abe, Gislane [UNIFESP]; Oliveira, Acary Souza Bulle [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Centro Universitário Adventista de São Paulo Neurologic Rehabilitation Service of the PoliclínicaOBJECTIVE: To determine the frequency and clinical manifestations of patients with post-poliomyelitis syndrome (PPS) in a Brazilian division of neuromuscular disorders. METHODS: A total of 167 patients with prior history of paralytic poliomyelitis was investigated for PPS, based on international diagnostic criteria. Other variables analyzed were: gender, race, age at poliomyelitis infection, age at PPS onset, and PPS symptoms. RESULTS: One hundred and twenty-nine patients presented PPS, corresponding to 77.2% of the studied population. 62.8% were women and 37.2% were men. Mean age of patients with PPS at onset of PPS symptoms was 39.9±9.69 years. Their main clinical manifestations were: new weakness in the previously affected limbs (69%) and in the apparently not affected limbs (31%); joint pain (79.8%); fatigue (77.5%); muscle pain (76%); and cold intolerance (69.8%). CONCLUSIONS: Most patients of our sample presented PPS. In Brazil, PPS frequency and clinical features are quite similar to those of other countries.
- ItemAcesso aberto (Open Access)Uso universal da vacina inativada contra poliomielite(Sociedade Brasileira de Pediatria, 2006-07-01) Carvalho, Luiza Helena Falleiros; Weckx, Lily Yin [UNIFESP]; Faculdade de Medicina de Marília; Faculdade de Medicina Metropolitana de Santos; Sociedade Brasileira de Pediatria Departamento de Infectologia; Instituto de Infectologia Emílio Ribas; Universidade Federal de São Paulo (UNIFESP); Secretaria da Saúde do Estado de São PauloOBJECTIVES: To present an update on the status of poliomyelitis worldwide, number of cases per year, regions most affected by the disease, vaccines currently available, their risks and benefits, monovalent vaccine use, risks of disseminating a mutant virus in the community, progress that has been made in terms of worldwide eradication and the World Health Organization.s (WHO) proposals in this transition period between global eradication and the post-eradication period. SOURCES OF DATA: Data for the period from 1955 to 2005 were searched in MEDLINE, LILACS, The Web, Doctor's Guide, WHO website and Pan American Health Organization (PAHO) website and text book. SUMMARY OF THE FINDINGS: In 1988, the WHO established the goal of eradicating the disease and interrupting transmission of the wild virus globally. Since then, there has been a dramatic decline of the disease, although in 2005 there were still some countries considered endemic and others where polio returned on account of imported viruses. The vaccines used worldwide are the classical tOPV and IPV, and in this eradication process, the use of mOPV vaccines has been encouraged in places where only one type of poliovirus circulates. In addition to spreading the virus in the community, the OPV vaccines may, however, cause paralyses by reversal of the neurovirulence process. CONCLUSIONS: For a world free of poliomyelitis disease, it would be necessary to interrupt circulation of the virus, which will only be possible if the OPV virus were to be discontinued, in accordance with the WHO proposals for this transition period and the post-eradication period.