Navegando por Palavras-chave "lactate threshold"

Agora exibindo 1 - 3 de 3
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Assessment of aerobic capacity during swimming exercise in ob/ob mice
    (Wiley-Blackwell, 2011-12-01) Almeida, W. S.; Lima, L. C. J.; Cunha, V. N. C.; Cunha, R. R.; Araujo, R. C.; Barros, C. C. [UNIFESP]; Simoes, H. G.; Campbell, C. S. G.; Univ Catolica Brasilia; Universidade Federal de São Paulo (UNIFESP)
    Obesity is a highly prevalent condition associated with several diseases. Physical exercise has been considered as a non-pharmacological tool in the treatment of obesity. However, several aspects underlying exercise evaluation and prescription in obesity and associated pathologies are still under investigation. Although many research involving exercise have been performed in animal models, there is a lack of protocols for aerobic capacity assessment in obese animals, such as the ob/ob mice. This study aimed the following: (i) to verify the possibility of determining the lactate threshold (LT) on swimming exercise in ob/ob mice and in non-obese heterozygote mice (ob/OB), through visual inspection (vLT) and polynomial adjustment (pLT); and (ii) to verify if the LT determined through these protocols corresponds to the maximal lactate steady state (MLSS). Eight ob/ob and ten ob/OB mice performed an incremental exercise test to determine vLT and pLT as well as constant-load exercise bouts to determine MLSS. There were no within-group differences between vLT, pLT and MLSS [ob/ob: similar to 5.3% body weight (BW); ob/OB: similar to 3 center dot 6%BW] with a high agreement among protocols. in conclusion, the identification of the LT and MLSS intensities was possible for both groups. These data suggest that the proposed protocols may be used in new research on the effects of different exercise intensities on some aspects of obesity. Copyright (c) 2011 John Wiley & Sons, Ltd.
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Effect of type 2 diabetes on plasma kallikrein activity after physical exercise and its relationship to post-exercise hypotension
    (Masson Editeur, 2010-11-01) Motta, D. F.; Lima, L. C. J.; Arsa, G.; Russo, P. S.; Sales, M. M.; Moreira, S. R.; Morais, P. K.; Almeida, W. S.; Araujo, R. C. [UNIFESP]; Moraes, M. R. [UNIFESP]; Pesquero, J. L.; Simoes, H. G.; Campbell, C. S. G.; Univ Catolica Brasilia; Universidade Federal de Minas Gerais (UFMG); Universidade Federal de São Paulo (UNIFESP); Fed Univ Vale do Sao Francisco
    Aim.-The present study was undertaken to determine the effects of type 2 diabetes (T2D) on plasma kallikrein activity (PKA) and postexercise hypotension (PEH).Methods. - Ten T2D patients (age: 53.6 +/- 1.3 years; body mass index: 30.6 +/- 1.0 kg/m(2); resting blood glucose: 157.8 +/- 40.2 mg dL(-1)) and 10 non-diabetic (ND) volunteers (age: 47.5 +/- 1.0 years; body mass index: 28.3 +/- 0.9 kg/m(2); resting blood glucose: 91.2 +/- 10.5 mg dL(-1)) underwent two experimental sessions, consisting of 20 mm of rest plus 20 min of exercise (EXE) at an intensity corresponding to 90% of their lactate threshold (90LT) and a non-exercise control (CON) session. Blood pressure (BP; Microlife BP 3ACI-1 monitor) and PKA were measured during rest and every 15 min for 135 min of the postexercise recovery period (RP).Results. - During the RP, the ND individuals presented with PEH at 30, 45 and 120 min (P < 0.05) while, in the T2D patients, PEH was not observed at any time. PKA increased at 15 min postexercise in the ND (P < 0.05), but not in the T2D patients.Conclusion. - T2D individuals have a lower PKA response to exercise, which probably suppresses its hypotensive effect, thus reinforcing the possible role of PKA on PEH. (C) 2010 Elsevier Masson SAS. All rights reserved.
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Exercise Training at MLSS Decreases Weight Gain and Increases Aerobic Capacity in Obese Zucker Rats
    (Georg Thieme Verlag Kg, 2014-03-01) Almeida, J. A.; Petriz, B. A.; Gomes, C. P. C.; Araujo, R. C. [UNIFESP]; Pereira, R. W.; Franco, O. L.; Univ Catolica Brasilia; Universidade Federal de São Paulo (UNIFESP)
    This study aimed to identify the aerobic capacity enhancement and subsequent body weight (BW) status of obese Zucker rats (OZRs) after 4 weeks of treadmill running exercise at the maximal lactate steady state (MLSS). in addition to obese Zucker rats (OZRs), lean Wistar Kyoto rats (WKYs) were used, and both species were divided into control and exercise groups as follows: obese exercise (OZR-EX, n=5), obese control (OZR-CON, n=5), lean exercise (WKY-EX, n=5) and lean control (WKY-CON, n=5). the OZR and WKY exercise groups trained 5 days per week at 12.5 m.min(-1) and 20 m.min(-1), respectively. After 4 weeks of training, MLSS was ascertained to evaluate the animals' aerobic capacity using 3 different velocities (12.5, 15 and 17.5 m.min(-1) for OZRs and 25, 30 and 35 m.min(-1) for WKYs). the MLSS of OZR-EX was identified at the velocity of 15 m.min(-1), representing a 20% increase in aerobic capacity after the exercise program. the MLSS of WKY-EX was identified at 30 m.min(-1) with a 50% increase of in aerobic capacity. Obese animals that exercised showed reduced weight gain compared to the non-exercise obese control group (p <0.05). Our results thus show that exercise training at MLSS intensity increased the aerobic capacity in both obese and non-obese animals and also reduced BW gain.