Navegando por Palavras-chave "gastrointestinal tract"

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    Efeitos do exercício físico sobre o trato gastrintestinal
    (Sociedade Brasileira de Medicina do Exercício e do Esporte, 2008-02-01) Lira, Claudio Andre Barbosa de [UNIFESP]; Vancini, Rodrigo Luiz [UNIFESP]; Silva, Antonio Carlos da [UNIFESP]; Nouailhetas, Viviane Louise Andree [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    The impact of exercise on the gastrointestinal tract (GI tract), although being little investigated, is a field of high interest. Intense endurance aerobic exercise can lead to gastrointestinal symptoms. These symptoms can be classified into upper symptoms (vomiting, nausea and retrosternal pyrosis - heartburn) and lower symptoms (diarrhea, abdominal cramps, loss of appetite, bleeding, accelerated bowel transit time, urge to defecate). These symptoms etiology during exercise is multifactorial and includes: reduction of intestinal blood flow, release of gastrointestinal hormones, mechanical stress on the GI tract, dehydration, psychological factors, age, gender, diet, and training status. On the other hand, low intensity exercise has a protective effect on the GI tract; mainly, with certain diseases, such as, colon cancer, diverticular disease, cholelithiases, and constipation. A variety of mechanisms have been postulated to explain the effects of exercise on the GI tract, contributing to the development of therapeutic strategies in the treatment of patients with gastrointestinal symptoms and diseases.
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    Infection Strategies of Intestinal Parasite Pathogens and Host Cell Responses
    (Frontiers Media Sa, 2016) Di Genova, Bruno M. [UNIFESP]; Tonelli, Renata R. [UNIFESP]
    Giardia lamblia, Cryptosporidium sp., and Entamoeba histolytica are important pathogenic intestinal parasites and are amongst the leading causes worldwide of diarrheal illness in humans. Diseases caused by these organisms, giardiasis, cryptosporidiosis, and amoebiasis, respectively, are characterized by self -limited diarrhea but can evolve to long-term complications. The cellular and molecular mechanisms underlying the pathogenesis of diarrhea associated with these three pathogens are being unraveled, with knowledge of both the strategies explored by the parasites to establish infection and the methods evolved by hosts to avoid it. Special attention is being given to molecules participating in parasite host interaction and in the mechanisms implicated in the diseases' pathophysiologic processes. This review focuses on cell mechanisms that are modulated during infection, including gene transcription, cytoskeleton rearrangements, signal transduction pathways, and cell death.