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- ItemAcesso aberto (Open Access)Avaliação da fatigabilidade em pacientes com esclerose múltipla através do dinamômetro manual(Academia Brasileira de Neurologia - ABNEURO, 2006-06-01) Pavan, Karina; Schmidt, Kizi; Ariça, Tatiana De Ambrosio; Mendes, Maria Fernanda [UNIFESP]; Tilbery, Charles Peter; Lianza, Sergio; ISCMSP; Universidade Federal de São Paulo (UNIFESP); Santa Casa de Misericórdia de São Paulo Faculdade de Ciências Médicas; FCMSCMSPFatigue is one of the most commom disabling symptoms in multiple sclerosis (MS). The aim of this study was to evaluate the fatigability on patients with MS by the aplication of hand grip isotonic and isometric exercises with dynamometer. As results the fatigability, the isometric strenght and time were statistically similar in the control group and in MS. We conclude that although fatigue is a frequent subjective complaint on MS, the fatigability and the recover after exercises seems to be normal.
- ItemAcesso aberto (Open Access)Circadian variation of fatigue in both patients with paralytic poliomyelitis and post-polio syndrome(Academia Brasileira de Neurologia - ABNEURO, 2013-07-01) Viana, Celiana Figueiredo [UNIFESP]; Pradella-Hallinan, Márcia Lurdes de Cássia [UNIFESP]; Quadros, Abrahão Augusto Juviniano [UNIFESP]; Marin, Luis Fabiano [UNIFESP]; Oliveira, Acary Souza Bulle [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Objective It was to evaluate the degree of fatigue in patients with paralytic poliomyelitis (PP) and with post-polio syndrome (PPS), and correlate it with parameters of sleep and the circadian cycle. Methods Thirty patients, 17 female (56.7%), participated in the study: they answered the Revised Piper Fatigue Scale and performed a nocturnal polysomnographic study. Eleven had PP (mean age±standard deviation of 47.9±6.4 years), and 19 had PPS (mean age±standard deviation of 46.4±5.6 years). Results Our study showed that fatigue was worse in the afternoon in the PP Group and had a progressive increase throughout the day in the PPS Group. We also observed compromised quality of sleep in both groups, but no statically significant difference was found in the sleep parameters measured by polysomnography. Conclusion Fatigue has a well-defined circadian variation, especially in PPS Group. Poor sleep quality is associated with fatigue and, therefore, sleep disturbances should be evaluated and treated in this group of PPS.
- ItemAcesso aberto (Open Access)Correlação entre qualidade de vida e capacidade funcional na insuficiência cardíaca(Sociedade Brasileira de Cardiologia - SBC, 2010-08-01) Nogueira, Ivan Daniel Bezerra [UNIFESP]; Servantes, Denise Maria [UNIFESP]; Nogueira, Patrícia Angélica de Miranda Silva; Pelcerman, Amália [UNIFESP]; Salvetti, Xiomara Miranda [UNIFESP]; Salles, Fernando [UNIFESP]; Almeida, Dirceu Rodrigues de [UNIFESP]; Mello, Marco Tulio de [UNIFESP]; Campos Filho, Orlando [UNIFESP]; Oliveira Filho, Japy Angelini [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade Federal do Rio Grande do NorteBACKGROUND: Patients with cardiac failure (CF) present progressive incapacity and decreased quality of life, both related to dyspnea and fatigue. Thus, there is the increasing interest in measring the quality of life (QL), by generic instrument, such as the 36-item Short-Form Health Survey (SF-36), by specific instrument, such as Minnesota Living with Heart Failure (MLHFQ). OBJECTIVE: This study has the objective to correlate the QL surveys, SF-36 and MLHFQ, with the functional capacity of patients with CF, expressed by the cardiopulmonary test and the TC6M. METHODS: Using the SF-36 and MLHFQ surveys for QL evaluation, for the evaluation of the functional capacity, it was used the cardiopulmonary test, being executed using a tredmill with Weber protocol, as well sa the distance covered in the walk test of six minutes (TC6M). RESULTS: Forty-six patients were selected with CF diagnosis (22 men, average age of 52 years old), classes II and III of New York Heart Association. It was observed that the mild correlation between the physical and emotional domains of SF-36 and VE/VCO2.peak (r=-0.3; p<0.05) and the distance covered in TC6M (r=0.4; p<0.05), respectively. It was also observed the mild to moderate correlations of MLHFQ total score with VO2.peak (r=-0.5; p<0.05), the aerobic threshold (r=-0.4; p<0.05) and the distance covered in TC6M (r=-0.5; p<0.05). CONCLUSION: The data suggest that the application of both evaluation instruments of QL, generic (SF-36) and specific (MLHFQ) in patients with CF, showed mild and moderate correlation with the variable of the cardiopulmonary test with the variables of the cardiopulmonary test and the distance covered in TC6M.
- ItemSomente MetadadadosDistúrbios de sono causam impacto na qualidade de vida de mulheres com lúpus eritematoso sistêmico (les)(Universidade Federal de São Paulo (UNIFESP), 2015-08-31) Reis, Lilian Karla Cunha dos [UNIFESP]; Trevisani, Virginia Fernandes Moca Trevisani [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Despite the small number of studies regarding sleep disorders, they are a frequent complaint of patients with SLE (62 to 80%) and are related to fatigue, pain, and decreased quality of life (Qol). Objective: To assess the impact of sleep disorders in Qol, pain, and fatigue in women with SLE. Methods: We used the following questionnaires, scales and indices: actigraphy to assess sleeping habits of women with SLE, the Pittsburgh Sleep Quality lndex (PSQI) questionnaire, Medical Outcomes short form 36 (SF-36), the Fatigue Severity Scale (FSS), the Visual Analogue Scale (VAS), the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI), and the Systemic Lupus International Collaboration Clinics (SLICC). The software used for data analysis was Minitab version 16.1, with a significance level of 5%. Results: We studied 46 women with SLE, who had subjective complaints of bad sleep (PSQI). When we related the PSQI data with the questionnaires, we observed associations with (FSS) (p=0.048), pain (VAS) (p=0.028), the role-physical (RP) (p = 0.017), the role emotional (RE) (p=0.006), and mental health (MH) scales (SF-36) (p = 0.034). In terms of correlation of the actigraphy variables with the scores of the questionnaires, we observed statistical significance correlation with the SF-36 data in the RE scale, as follows: with sleep latency (SL) (p=0.005), number of wake ups after sleep onset (p=0.038) and sleep efficiency (p=0.046). In the use of drugs: yes or no, the only association that we observed was the use of antimalarial drugs and greater SL (p=0.032). The association of the use of prednisone (PDN) and less total sleep time (TST) almost reached significant value (p=0.056). Conclusion: Our study indicates that patients with SLE and sleep disorders experience a negative impact in terms of fatigue, pain, and some scales of Qol (in the RP, RE and MH scales), particularly role emotional, with increased latency and wake ups after sleep onset, reducing sleep efficiency; in addition to the influence of corticoids and antimalarial drugs over these alterations. We also observed consistency in both evaluation methods (actigraphy and PSQI) in sleep latency. We have no conflict of interest in this study.
- ItemSomente MetadadadosEfeito da apneia obstrutiva do sono de grau leve sobre a sonolência excessiva diurna, fadiga e atenção sustentada(Universidade Federal de São Paulo (UNIFESP), 2016-05-04) Paiva, Luciana Badke Neves de [UNIFESP]; Bittencourt, Lia Rita Azeredo Bittencourt [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Background: Moderate to severe obstructive sleep apnea (OSA) directly affects the excessive daytime sleepiness, fatigue and sustained attention of individuals, but it has not yet been established in the literature, if these changes also affect patients with mild OSA. Objectives: Evaluate whether patients with mild OSA suffer negative effects in their excessive daytime sleepiness, fatigue and sustained attention Methods: Were included volunteers of both genders, body mass index (BMI) ?35 kg/m2 and age between 18 and 65 years. In the mild OSAS group, patients with an apnea-hypopnea index (AHI) score of ?5 and?15 events/h of sleep were included. In the control group were included individuals with an AHI <5 events/h of sleep, a respiratory disturbance index (RDI) score ?5, an arousal index score ?15, an Epworth sleepiness scale (ESS) value <9. Both groups performed the following procedures: baseline data, complete full-night PSG exam, subjective excessive daytime sleepiness (Karolinska Sleepiness Scale and Stanford Sleepiness Scale) and objective sleepiness (Maitenance Wakefullness Test), Fatique (Modified Fatigue Impact Scale) and sustained attention (Psychomotor Vigilance Task (PVT). For Statistical analysis we performed a descriptive analysis (mean±standard deviation) and to compare the groups we performed the general linear model (GLM). A linear regression was performed to compare diferents subjectives and objectives scales of daytime sleepiness. Results: 60 volunteers were included in the study, of which 30 were allocated to the mild OSA group and 30 to the control group and were matched with respect to sex, age and BMI. In the analysis of descriptive variables, we observed higher neck in the mild OSA group (38.28±3.05 e 36.48±3.64cm, p=0.001), with no difference in the analysis of age and BMI. In the analysis of subjective and objective sleepiness and fatigue, we observed no differences between groups. With respect to sustained attention, as evaluated using the PVT, there was higher mean values of lapses in the OSA group compared with control group (2.94 ± 2.76 e 1.90 ± 1.17, p=0.04). In the analysis of the relationship between subjective and objective sleepiness, we observed a relationship between the PVT ?Mean RT? and subjective sleepiness mensured with Stanford Sleepines Scale (p=0,02) and Karolinska Sleepinesss Scale (p=0,005). We also observed a relationship between Maitenance Wakefullness Test and lapses attencion. Conclusions: Patients with mild OSA showed increased sustained attention lapses and there was no difference in the subjective and objective sleepiness and fatique compared with normal subjects.
- ItemAcesso aberto (Open Access)Efeito do jateamento abrasivo na integridade superficial e na vida em fadiga do aço Maraging 18Ni300 nas condições: solubilizada, envelhecida e super-envelhecida(Universidade Federal de São Paulo, 2022-09-21) Palau, José Carlos Fortes; Travessa, Dilermando Nagle; Reis, Danieli Aparecida Pereira; http://lattes.cnpq.br/7058867464306125; http://lattes.cnpq.br/9887081576919853; http://lattes.cnpq.br/8213002072319262O jateamento abrasivo a seco, também conhecido como "grit blasting", é um processo erosivo de tratamento superficial mecânico a frio amplamente utilizado no meio industrial para remoção de contaminantes superficiais e preparação de superfície para aplicação de revestimentos diversos. Os aços maraging são uma classe especial de aços de ultra-alta-resistência que apresentam uma combinação única de altos níveis de resistência mecânica aliada a uma excelente tenacidade "e, por essas razões" são empregados principalmente em setores estratégicos como o aeroespacial e o nuclear. Alterações na textura superficial (rugosidade), no estado de tensões residuais e na microestrutura da superfície deformada estão entre os principais efeitos produzidos pelo processo de jateamento abrasivo na integridade da superfície jateada. Dessa forma, o objetivo desse presente trabalho foi avaliar se os efeitos produzidos pelo processo de tratamento superficial mecânico de jateamento abrasivo a seco com partículas metálica abrasiva angular na superfície do aço maraging 18Ni300 poderiam influenciar em sua vida em fadiga, uma vez que, a fadiga é o mecanismo de falha dominante de vários componentes de engenharia e, por sua vez, sofre forte influência de sua qualidade superficial. O estudo foi conduzida em duas etapas: i) na primeira etapa amostras de aço maraging 18Ni300 foram tratadas por diferentes rotas de tratamentos térmicos, para obtenção de diferentes microestruturas e níveis de resistência mecânica e, posteriormente submetidas ao processo de jateamento abrasivo, utilizando-se dois ângulos de impacto das partículas (45◦e 75◦). Os efeitos produzidos pelo jateamento na superfície deformada foram avaliados através de caracterização microestrutural, caracterização mecânica, perfilometria de contato e difração de raios-X. ii) na segunda etapa as condições mais desfavoráveis para a vida em fadiga, encontrados após análise dos resultados obtidos nos corpos de prova da primeira etapa, foram replicados em corpos de prova de fadiga divididos em dois grupos com diferentes condições superficiais: um com a superfície polida, adotado como a condição superficial padrão e o outro com a superfície jateada. Os corpos de provas nas condições superficiais polido e jateado foram testados em condições de fadiga axial com carregamento de amplitude reversa (R=-1) em vários níveis de tensões e seu desempenho avaliado pelas curvas S-N e as superfícies fraturadas analisadas por microscopia eletrônica de varredura. Os resultados obtidos nos ensaios de fadiga e nas análises fractográficas revelaram que o jateamento abrasivo apesar de ter aumentado significativamente a rugosidade superficial (em mais de 10 vezes), resultou na melhora da vida em fadiga ao induzir na superfície jateada uma combinação de efeitos benéficos como o trabalho à frio (encruamento) que aumentou a dureza superficial (aproximadamente em 6,74%) e tensões residuais compressivas na profundidade (até 180-200 µm) da superfície jateada, que contribuíram para retardar o início e a propagação das trincas e, assim, aumentar a vida em fadiga no aço maraging 18Ni300.
- ItemSomente MetadadadosEfeitos agudos do laser terapêutico aplicado aos membros inferiores na potência muscular e na aptidão cardiorrespiratória em adultos saudáveis(Universidade Federal de São Paulo (UNIFESP), 2013-05-29) Alves, Mariana Agnes da Silva [UNIFESP]; Dourado, Victor Zuniga [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Despite the positive effects of low-level laser therapy (LLLT) on muscle fatigue before exercises using single muscle group, the acute effects of LLLT on performance in cardiopulmonary exercise testing (CPET) are poorly understood. We aimed to determine the effect of LLLT before CPET on gas exchange and electromyographic response in health adults. A randomized double-blind placebo-controlled crossover trial was performed with 18 untrained participants (9 males; 22 ± 2 yr). The LLLT or placebo was applied to quadriceps and gastrocnemius 10 min before a rapidly incremental cycleergometer CPET randomly performed in alternate days. The LLLT was performed using a multi-diode cluster with 7 emitting diodes (850 nm, 100 mW, 2J/diode). Physiological responses were continuously monitored during the CPETs using a gas analyzer. The electromyographic fatigue threshold (EMGth) was assessed with surface electrodes on vastus lateralis. The root mean square (RMS) was plotted every 5 s against the exercise intensity. The EMGth was visually detected as the breakpoint in RMS values throughout the CPET. Compared to placebo, the LLLT significantly increased peak O2 uptake (V’O2: 33 ± 10 vs. 31 ± 9 mL/min/kg). We observed a shallower slope of the Δheart rate/ΔVO 2 during the CPET after LLLT compared to placebo, i.e., increased cardiovascular efficiency (56 ± 24 vs. 66 ± 30 bpm/L/min). There were no LLLT related changes in EMGth. We may conclude that the LLLT acutely increase exercise performance in healthy untrained adults primarily due to increased O2 extraction by peripheral muscles without causing significant impact on muscle fatigue.
- ItemAcesso aberto (Open Access)Effects of prolonged running performed at the intensity corresponding to the onset of blood lactate accumulation, on maximum isokinetic strength in active non-athletic individuals(Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia, 2007-06-01) Denadai, Benedito Sérgio; Greco, Camila Coelho; Tufik, Sergio [UNIFESP]; Mello, Marco Tulio de [UNIFESP]; Universidade Estadual Paulista (UNESP); Universidade Federal de São Paulo (UNIFESP)OBJECTIVE: The objective of this study was to analyze the effects of prolonged continuous running performed at the intensity corresponding to the onset of blood lactate accumulation (OBLA), on the peak torque of the knee extensors, analyzed in relation to different types of contraction and movement velocities in active individuals. METHOD: Eight men (23.4 ± 2.1 years; 75.8 ± 8.7 kg; 171.1 ± 4.5 cm) participated in this study. First, the subjects performed an incremental test until volitional exhaustion to determine the velocity corresponding to OBLA. Then, the subjects returned to the laboratory on two occasions, separated by at least seven days, to perform five maximal isokinetic contractions of the knee extensors at two angular velocities (60 and 180º.s-1) under eccentric and concentric conditions. Eccentric peak torque (EPT) and Concentric peak torque (CPT) were measured at each velocity. One session was performed after a standardized warm-up period (5 min at 50% VO2max). The other session was performed after continuous running at OBLA until volitional exhaustion. These sessions were conducted in random order. RESULTS: There was a significant reduction in CPT only at 60º.s-1 (259.0 ± 46.4 and 244.0 ± 41.4 N.m). However, the reduction in EPT was significant at 60º.s-1 (337.3 ± 43.2 and 321.7 ± 60.0 N.m) and 180º.s-1 (346.1 ± 38.0 and 319.7 ± 43.6 N.m). The relative strength losses after the running exercise were significant different between contraction types only at 180º.s-1. CONCLUSION: We can conclude that, in active individuals, the reduction in peak torque after prolonged continuous running at OBLA may be dependent on the type of contraction and angular velocity.
- ItemEmbargoEstudo do comportamento em fadiga de compósitos poliméricos de poliamida 6, poli(sulfeto de p-fenileno) e resina epóxi reforçados com fibra de carbono visando aplicação no setor automobilístico(Universidade Federal de São Paulo, 2024-09-25) Morgado, Guilherme Ferreira de Melo [UNIFESP]; Rezende, Mirabel Cerqueira [UNIFESP]; Passador, Fabio Roberto [UNIFESP]; http://lattes.cnpq.br/0152213852695153; http://lattes.cnpq.br/3744737176516322; https://lattes.cnpq.br/4205759258300585A crescente utilização de compósitos estruturais com matrizes termoplásticas e termorrígidas na indústria automobilística deve-se às suas vantagens, como maior eficiência peso-potência, versatilidade no processamento e potencial para reúso e reciclagem. No entanto, uma das principais causas de falha em materiais é a fadiga, caracterizada por carregamentos cíclicos e deformações plásticas localizadas; porém, ainda pouco explorada na área de compósitos poliméricos estruturais. Nesse contexto, o presente trabalho visa contribuir na área de compósitos para uso no setor automotivo, por meio de um estudo sistemático de fadiga de compósitos termoplásticos (poliamida 6 (PA6) e poli(sulfeto de p-fenileno) (PPS)) e termorrígido (resina epóxi de cura rápida), reforçados com fibra de carbono (FC). Os compósitos foram preparados por moldagem por compressão a quente e avaliados quanto à qualidade do processamento (ultrassom e digestão ácida), propriedades mecânicas estáticas (tração e resistência ao cisalhamento interlaminar) e dinâmicas (fadiga), além de análises dinâmico-mecânicas (DMA), calorimetria exploratória diferencial (DSC), termogravimetria (TGA) e microscopia eletrônica de varredura. Os resultados obtidos mostraram que o laminado de FC/PPS apresentou a maior resistência em fadiga (640 MPa), seguido pelo de FC/PA6 (459 MPa) e o de FC/resina epóxi (360 MPa). Já os compósitos de FC/resina epóxi e FC/PPS apresentaram maior rigidez nos ensaios de tração e o de FC/PPS apresentou a maior resistência em cisalhamento. As análises de DMA permitiram determinar as temperaturas de transição vítrea (Tg) de 105 °C e 147 °C dos laminados de FC/PPS e FC/resina epóxi, respectivamente. As análises de TGA mostraram que o laminado de FC/PPS apresentou a maior estabilidade térmica. As análises morfológicas das superfícies de fratura das amostras ensaiadas mecanicamente revelaram os aspectos fractográficos presentes, os quais contribuíram para elucidar as extensões dos danos causados pelos ensaios mecânicos. A correlação dos dados obtidos neste estudo mostra que o laminado de FC/PPS apresentou o melhor desempenho mecânico e, de maneira geral, o estudo realizado dá subsídios importantes para o desenvolvimento de compósitos estruturais aplicados no setor automotivo.