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- ItemSomente MetadadadosUltrasound enhanced synthesis of 1,5-benzodiazepinic heterocyclic rings(Elsevier B.V., 2006-11-13) Guzen, Karla P.; Cella, Rodrigo; Stefani, Helio A.; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)1,5-Benzodiazepines are synthesized by a reaction of o-phenylenediamines with a diketone or ketones series by ultrasound irradiation in presence of APTS. the condensation occurred in a mild condition with good to excellent yields. (c) 2006 Elsevier B.V. All rights reserved.