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- ItemSomente MetadadadosAerobic exercise capacity in normal adolescents and those with type 1 diabetes mellitus(Blackwell Publishing, 2005-09-01) Komatsu, Willian R.; Gabbay, Monica Andrade Lima [UNIFESP]; Lazaretti-Castro, Marise [UNIFESP]; Saraiva, Gabriela L.; Chacra, Antonio Roberto; Barros Neto, Turibio Leite [UNIFESP]; Dib, Sergio A.; Universidade Federal de São Paulo (UNIFESP)Objective: To compare the aerobic exercise capacity between normal adolescents and those with type I diabetes mellitus (T1DM).Methods: An experimental group with 72 individuals diagnosed with T1DM aged 9-20, time from diagnosis 4.9 +/- 3.6 yr, without clinical cardiopulmonary disease or anemia and a control group (C) with 46 healthy individuals aged 10-18, matched by age, weight, height, body mass index, and lean and fat mass (kg), underwent an incremental aerobic exercising test on a motorized treadmill, where gas exchange variables - peak pulmonary ventilation (VE), peak oxygen consumption (VO2), and carbon dioxide production (CO2) - as well as their heart rate (HR) and time to exhaustion were recorded.Results: Body mass composition had no significant difference between experimental and control groups, and male and female subjects had similar exercising performances. the mean of hemoglobin A1c in the control group was 5.2 +/- 0.9% and in the diabetic group 8.1 +/- 2.2%; p = 0.000. the patients with T1DM showed lower levels of aerobic capacity than the control group. Their respective values for each variable were as follows: (i) maximal VO2 (T1DM: 41.57 +/- 7.68 vs. C: 51.12 +/- 9.94 mL/kg/min; p < 0.001) and (ii) maximal VE (T1DM: 76.39 +/- 19.93 vs. C: 96.90 +/- 25.72 mL/kg/min; p < 0.001). Patients with T1DM also had an earlier time to exhaustion (T1DM: 8.75 +/- 1.60 vs. 10.82 +/- 1.44 min).Conclusions: Adolescent patients with T1DM showed a reduced aerobic exercising capacity when compared to healthy peers matched to anthropometric conditions. This potential condition should be taken into consideration by the time of evaluation of the aerobic performance of these patients with glycemic control level.
- ItemSomente MetadadadosAn application of bootstrap resampling method to obtain confidence interval for percentile fatness cutoff points in childhood and adolescence overweight diagnoses(Nature Publishing Group, 2005-03-01) Colugnati, Fernando Antonio Basile [UNIFESP]; Louzada-Neto, F.; Taddei, Jose Augusto de Aguiar Carrazedo [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)OBJECTIVE: To present a resampling approach to obtain confidence intervals (CIs) and the empirical distributions for the studentized regression residuals percentiles when used as cutoff points for overweight and obesity diagnosis in children and adolescents.METHOD: A tutorial for the nonparametric bootstrap with bias accelerating correction is presented. A classical method, the Binomial interpretation, is used as comparing criterion.SUBJECTS: A case study comprising 418 randomly selected subjects from a private secondary school (age: 10-17 y, boys: 52%).MEASUREMENTS: Body fat percentage (by), age (y) and Tanner criteria.RESULTS: the empirical distributions presented skewness suggesting that the CIs should not be symmetric. CIs obtained by the proposed approach were more realistic than the classical ones.CONCLUSIONS: We propose a simple and efficient way to obtain the interval estimates and the distribution properties of cutoff points for overweight and obese classification using a sample-based method that allows the comparison of cutoffs among many subpopulations.
- ItemAcesso aberto (Open Access)Assessment and nutrition education in patients with amyotrophic lateral sclerosis(Assoc Arquivos Neuro- Psiquiatria, 2016) Almeida, Claudinea dos Santos [UNIFESP]; Stanich, Patricia [UNIFESP]; Salvioni, Cristina Cleide dos Santos [UNIFESP]; Diccini, Solange [UNIFESP]Neurological patients with amyotrophic lateral sclerosis (ALS) often deteriorate to a worsening nutritional status. The aim of this study was to compare the nutritional status and food intake after nutrition education in patients with ALS. Clinical, anthropometric and functional variables were analyzed. Fifty-three patients were monitored at an early stage of the disease. The average score on the functionality scale was 33 points. Initially only 3.8% were classified as low body weight. After three months, 50% showed significant variation in anthropometric measures related to muscle mass and body fat reserves without association with clinical variables. After nutritional guidance, there was an increase in the intake of all food groups, especially the dairy group (p < 0.05). The change of the nutritional status occurs early in patients with amyotrophic lateral sclerosis, even in those previously eutrophic or over weight. There was an increase in food intake after nutritional guidance according to the food guide adapted to the Brazilian population.
- ItemAcesso aberto (Open Access)Atividade física, horas de assistência à TV e composição corporal em crianças e adolescentes(Sociedade Brasileira de Cardiologia - SBC, 2010-08-01) Rivera, Ivan Romero; Silva, Maria Alayde Mendonça da; Silva, Renata D'andrada Tenório Almeida; Oliveira, Bruno Almeida Viana de; Carvalho, Antonio Carlos [UNIFESP]; Universidade Federal de Alagoas Faculdade de Medicina; Universidade Federal de São Paulo (UNIFESP)BACKGROUND: Physical inactivity is a predisposing factor to the onset/worsening of other cardiovascular risk factors, particularly obesity. OBJECTIVE: To determine physical activity level (PAL) and daily number of hours of TV (HTV) and the association and/or correlation of these variables with age, gender, economic class, public/private school, overweight and obesity in children and adolescents. METHODS: Cross sectional study, school-based population, public and private education, primary and secondary education. The sample was calculated based on the minimum expected prevalence of several variables, including physical inactivity. Cluster sampling. Protocol: structured questionnaire, including Physical Activity for Older Children Questionnaire (PAQ-C) measurements of weight, height, body mass index (BMI) and triceps skinfold (TSF). Statistical analysis: Chi-square, linear correlation. RESULTS: Among the 1,253 students, averaging 12.4 ± 2.9 years old, of which 549 were male, there was a prevalence of inactivity in 93.5%, more commonly found in female adolescents and there was no association between PAL and excess weight or body fat, soccer and dance were the most frequent activities in boys and girls, respectively; 60% of students did not have physical education classes. Average and median HTV were respectively 3.6 and 3 hours; there was a significant association between HTV and obesity and significant correlation between PAL and age (negative) and between BMI and TSF (positive). CONCLUSION: Physical inactivity is present in 93.5% of children and adolescents from Maceió. It is more commonly found among teenagers and females, with no association or correlation of this variable with excess weight or body fat; obesity was associated with > 3 HTV.
- ItemAcesso aberto (Open Access)Avaliação do estado nutricional e da composição corporal das crianças índias do Alto Xingu e da etnia Ikpeng(Sociedade Brasileira de Pediatria, 2004-12-01) Fagundes, Ulysses [UNIFESP]; Kopelman, Benjamin Israel [UNIFESP]; Oliva, Carlos Alberto Garcia [UNIFESP]; Baruzzi, Roberto Geraldo [UNIFESP]; Fagundes-Neto, Ulysses [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)OBJECTIVES: To assess the nutritional and body composition of two Brazilian indigenous populations by comparing their nutritional status. METHODS: 95 children from Alto Xingu and 69 from Ikpeng were evaluated, ages ranged from 24 to 117 months. The study was performed in the Xingu Indigenous Park. Data collected were: age, weight, height, skin folds, arm circumference, resistance and reactance. The z-scores were calculated and classified according to the parameters defined by the National Center for Health Statistics (NCHS 2000). Shortness was defined as length or stature below -2, underweight as body mass index below -2, and overweight as body mass index above 2. RESULTS: Among children from Alto Xingu, the prevalence of shortness was 8.4%, while among Ikpengs the prevalence was 37.7% (p < 0.001). Underweight was diagnosed in 12.5% of Ikpeng's children. Values of fat-free mass were greater for children from Alto Xingu and no case of obesity was found. CONCLUSION: In this study, Ikpeng's children showed higher incidences of short stature and low weight than the Altoxingu's children. Data regarding body composition have greater values among children from Alto Xingu, thus we conclude that nutritional status among children from Alto Xingu is better than the one found among the Ikpeng's children.
- ItemSomente MetadadadosAvaliação do impacto de intervenção nutricional na composição corporal de adolescentes com lúpus eritematoso sistêmico juvenil(Universidade Federal de São Paulo (UNIFESP), 2015-11-12) Abad, Thais Tobaruela Ortiz [UNIFESP]; Terreri, Maria Teresa de Sande e Lemos Ramos Ascensao Terreri [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Objective: to evaluate the impact of a dietary intervention in body composition changes and food intake of adolescents with juvenile Systemic Lupus erythematosus; to evaluate the association between body composition changes and physical activity, disease activity and medication use. Methods: thirty-one female adolescents with juvenile Systemic Lupus erythematosus, aged between 10 and 19 years old and minimum time of diagnosis of 6 months. In moment 1 (pre-intervention) body composition exam was performed and questionnaires of physical activity and food intake (24-hour recall) were applied. Patients were randomized into two groups: nutritional intervention and control group (no intervention). After a nine-month intervention, the exam and the questionnaires were repeated. Results: In the intervention group, we observed significant reduction in calorie (p=0.017), carbohydrate (p=0.030), total fat (p=0.020), saturated fat (p=0.013) and trans fat (p=0.012) intake. After nine months, control group presented increase in BMI (p=0.016), fat percentage (p=0.023), fat mass (p=0.024), trunk fat (p=0.005) and fat mass index (p=0.047) and appendicular fat index (p=0.016). No significant changes were observed in the intervention group. There was an average increase of 3.66kg of fat mass (p=0.013) and 0.36kg/m2 of appendicular fat index (0.007) in the control group. Conclusion: a nine-month dietary intervention aiming at healthy food behavior in teenagers with juvenile Systemic Lupus erythematosus is effective in promoting better food habits and seems to protect excess weight and fat mass gain.
- ItemSomente MetadadadosAvaliação e educação nutricional em pacientes com esclerose lateral amiotrófica(Universidade Federal de São Paulo (UNIFESP), 2016-01-27) Almeida, Claudinea dos Santos [UNIFESP]; Diccini, Solange Diccini [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Aim: The aim of the study was to evaluate the nutritional status and food intake at the time of the diagnosis and after nutritional guidance. Material and method: Quantitative study of longitudinal design clinical, anthropometric and functional variables were analyzed. The patients were divided into groups for nutritional guidance. Results: 3 patients were monitored with early stage of the disease. Appendicular form was predominant (79.2%).The time between onset of symptoms and diagnosis was 360 days.The average score on the functionality scale was 33 points.Initially only 3.8% were classified as low body weight.After three months, 50% showed significant variation in anthropometric measures related to muscle mass and body fat reserves without association with clinical variables.After nutritional guidance, there was an increase in the intake of all food groups with relevance to the dairy group (p <0.05). Conclusions: The change ofthe nutritional status occurs early in patients with ALS, even in those previously eutrophics or overweight.We have not observed a direct relationship between clinical variables and nutritional worsening. There was an increase in food intake after nutritional guidance according to the food guide adapted to the Brazilian population.
- ItemSomente MetadadadosBody Composition in Prepubertal, HIV-Infected Children: A Comparison of Bioelectrical Impedance Analysis and Dual-Energy X-Ray Absorptiometry(Sage Publications Inc, 2013-04-01) Palchetti, Cecilia Zanin [UNIFESP]; Patin, Rose Vega [UNIFESP]; Machado, Daisy Maria [UNIFESP]; Szejnfeld, Vera Lucia [UNIFESP]; Menezes Succi, Regina Celia de [UNIFESP]; Oliveira, Fernanda Luisa Ceragioli [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Background: the aim of this study was to compare bioelectrical impedance analysis (BIA) equations developed for healthy pediatric populations and for HIV-infected children using dual-energy X-ray absorptiometry (DXA) as the gold standard. Materials and Methods: A cross-sectional study was carried out with 40 prepubertal, HIV-infected children who regularly attended the Pediatric Infectious Disease Clinic at the Universidade Federal de São Paulo, São Paulo, Brazil. the study was conducted from August to November 2008. Demographic data, clinical parameters, immunological status, and use of antiretroviral therapy were obtained from the patients' medical records. We performed anthropometric parameters and body composition analyses, analyzed body composition by BIA and DXA, and compared the results obtained from BIA through using equations for both healthy and HIV-infected populations. Results: the mean +/- SD age of the study population was 9.8 +/- 1.2 years. Half of the population were females, and 82.5% of the children were clinically classified as B and C. Total body fat, by both absolute mass and by percentage, exhibited high homogeneity between the results obtained from BIA and DXA. However, there was no concordance in fat-free mass. the equation for healthy children showed good sensitivity and specificity when comparing the percentage of total body fat measured by DXA. Conclusion: BIA provides reliable data on total body fat but not fat-free mass when compared with DXA. the BIA equation developed for healthy pediatric populations can be used to determine total body fat in HIV-infected children. (Nutr Clin Pract. 2013; 28: 247-252)
- ItemSomente MetadadadosBody mass index and body composition in relation to sexual maturation(Freund Publishing House Ltd, 2008-02-01) Castilho, Silvia Diez; Cocetti, Monize; Barros Filho, Antonio de Azevedo; Universidade Federal de São Paulo (UNIFESP); Univ Catolica CampinasAim: To assess body mass index. (BMI) in relation to sexual maturation and verify how fat-free mass (FFM) and fat mass (FM) contribute to its increase.Methods: 1,275 White adolescents (656 girls and 619 boys), aged 9 to 18 years, were evaluated according to Tanner stages. FFM and FM were calculated by triceps and subscapular skinfold measurements and leg-to-leg bioelectrical impedance. BMI-for-maturation was distributed into percentiles. Fat-free mass index (FFMI) and body fat mass index (BFMI) were calculated based on BMI 50(th) percentile values.Results: During maturation, as BMI increases, girls gain FFMI (13.3 kg/m(2) at 131 and 15.8 kg/m(2) at 135) and BFMI (3.7 kg/m(2) at B1 and 5.7 kg/m(2) at B5) - proportionally more fat - while boys gain FFMI (14.3 kg/m(2) at G1 and 17.9 kg/m(2) at G5) and lose BFMI (4.8 kg/m(2) at G1 and 3.2 kg/m(2) at G5).Conclusion: These data suggest that FFMI and BFMI-for-maturation should be assessed in adolescents monitored for overweight and obesity.
- ItemSomente MetadadadosChanges in HDL-c concentrations after 16 weeks of combined training in postmenopausal women: characteristics of positive and negative responders(Canadian Science Publishing, Nrc Research Press, 2018) Diniz, Tiego A.; Rossi, Fabricio E.; Souza Fortaleza, Ana Claudia; Neves, Lucas Melo; Destro Christofaro, Diego Giulliano; Buonani, Camila; Lira, Fabio S.; Campos, Eduardo Zapaterra; do Prado, Wagner Luiz [UNIFESP]; Freitas, Ismael Forte, Jr.This study aimed to investigate the individual characteristics of body composition and metabolic profile that could explain interindividual variation in high-density lipoprotein cholesterol (HDL-c) concentrations in response to 16 weeks of combined strength plus aerobic (combined) training in postmenopausal women. The participants were divided into tertiles based on percentage of changes in HDL-c concentrations after combined training. Only women in the upper tertile (positive responders: Delta > 10.4%
- ItemSomente MetadadadosClinical value of anthropometric estimates of leg lean volume in nutritionally depleted and non-depleted patients with chronic obstructive pulmonary disease(Cambridge Univ Press, 2008-08-01) Villaca, Debora Strose [UNIFESP]; Lerario, Maria Cristina [UNIFESP]; dal Corso, Simone [UNIFESP]; Napolis, Lara [UNIFESP]; Pereira de Albuquerque, Andre Luiz [UNIFESP]; Lazaretti-Castro, Marize [UNIFESP]; Sachs, Anita [UNIFESP]; Nery, Luiz Eduardo [UNIFESP]; Neder, Jose Alberto [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)This study aimed to investigate the clinical usefulness of an anthropometrically based method for estimating leg lean volume (LLV) in patients with chronic obstructive pulmonary disease (COPD) who presented or not with nutritional depletion. We prospectively evaluated a group of forty-eight patients (thirty-eight males) with moderate to severe COPD (Global Initiative for Chronic Obstructive Lung disease stages II-IV) who underwent a 6 min walking test and knee isokinetic dynamometry. Leg lean mass (muscle mass plus bone) was determined by dual-energy X-ray absorptiometry (DEXA) with derivation of its respective volume: these values were compared with those obtained by the truncated cones method first described by Jones and Pearson in 1969. As expected, depleted patients (n 19) had reduced exercise capacity and impaired muscle performance as compared to non-depleted subjects (P<0.01). the mean bias of the LLV differences between anthropometry and DEXA were 0.40 litre (95 % CI - 0.59, 1.39) and 0.50 litre (95% CI - 1.08, 2.08) for depleted and non-depleted patients, respectively. Anthropometrically and DEXA-based estimates correlated similarly with muscle functional attributes. A ROC curve analysis revealed that leg height-corrected LLV values had acceptable sensitivity and specificity to identify depleted patients (area under the curve 0.93 (range 0.86-1.00); P<0.001). Moreover, patients with LLV <= 9.2 litres/m (the best cut-off value according to the ROC curve) had significantly lower exercise capacity and muscle performance than their counterparts (P<0.05). in conclusion. an anthropometrically based method of estimating LLV (Jones and Pearson method) was shown to present with clinically acceptable accuracy and external validity in depleted and non-depleted patients with stable COPD.
- ItemSomente MetadadadosComparison of techniques to evaluate adiposity in stunted and nonstunted children(Amer Acad Pediatrics, 2006-04-01) Hoffman, Daniel J.; Sawaya, Ana Lydia [UNIFESP]; Martins, Paula Andrea [UNIFESP]; McCrory, Megan A.; Roberts, Susan B.; Rutgers State Univ; Universidade Federal de São Paulo (UNIFESP); Bastyr Univ; Tufts UnivOBJECTIVE. the use of anthropometric measures (eg, skinfold thicknesses, BMI) to assess obesity is not without controversy and has not been explored with respect to the use among groups of children with growth retardation (ie, stunting). Therefore, the objective of this study was to determine whether growth retardation affects the accuracy of field methods for assessing body composition in children.METHODS. A cross-sectional study was conducted in 30 stunted children and 30 nonstunted children who were matched for age- and weight-for-height z score and living in the shantytowns of São Paulo, Brazil. Body composition (fat mass, fat-free mass, and percentage of body fat [%BF]) was measured by (H2O)-O-18 dilution (reference technique) using group-specific values for the hydration of fat-free mass and dual-energy x-ray absorptiometry. BMI and body composition that were calculated from 3 pediatric skinfold prediction equations were evaluated for accuracy of %BF in comparison with the reference technique.RESULTS. Stunted children were shorter and weighed less than nonstunted children, but BMI did not differ significantly between groups. All 3 skinfold equations tested resulted in a calculated %BF that was significantly lower than that measured by (H2O)-O-18 dilution for both stunted and nonstunted groups, and %BF as calculated by any of the skinfold equations tested did not significantly predict %BF by (H2O)-O-18 dilution. in contrast, BMI significantly predicted %BF in both stunted and nonstunted children, and this relationship did not differ by growth status.CONCLUSION. BMI but not skinfolds significantly predicted %BF measured by (H2O)-O-18 dilution. the relationship between BMI and %BF did not differ between stunted and nonstunted children; this indicates that BMI can be used in field studies of obesity and stunting. However, the prediction of %BF by BMI is relatively poor in both groups of children, and continued investigation of more accurate field methods for measuring %BF is warranted.
- ItemAcesso aberto (Open Access)Composição corporal e densidade mineral óssea em crianças e adolescentes pré-puberes infectados pelo HIV(Universidade Federal de São Paulo (UNIFESP), 2014) Palchetti, Cecília Zanin [UNIFESP]; Oliveira, Fernanda Luisa Ceragioli [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Objetivo: Avaliar prospectivamente as alteracoes ocorridas na composicao corporal de pacientes infectados pelo HIV e identificar as variaveis determinantes de lipodistrofia ao longo do tempo. Metodos: Estudo de coorte prospectivo, avaliado em periodo de dois anos e meio, incluindo 35 pre-puberes infectados pelo HIV, ambos os sexos, entre 7 a 12 anos atendidos em centro de referencia. Os pacientes foram distribuidos em dois grupos: sem lipodistrofia (SL) e com lipodistrofia (CL). Compararam-se dados clinicos, antropometricos, de composicao corporal e bioquimicos alem da determinacao dos fatores preditores de lipodistrofia no tempo 1 (T1) e tempo 2 (T2). Resultados: A media (DP) de idade foi de 9,6(1,1) e 11,6 (1,2) anos, no T1 e T2, respectivamente. No T2, 16 (45,7%) criancas continuavam pre-puberes. O grupo CL (n=8) apresentou maior prevalencia de baixa estatura (p =0,008) no T1, maiores valores de insulina (p=0,010) e HOMA-IR (p=0,013) e reducao da dobra cutanea tricipital (p=0,026) no T2 comparado ao grupo SL (n=27). Nos dois tempos, observou-se menores concentracoes de HDLc (p=0,027), maiores valores de relacao tronco/braco (p=0,002;p=0,001) e menores valores da relacao braco+perna/tronco (p=0,001) no grupo CL. No T1, os fatores preditores independentes de lipodistrofia foram baixa estatura (OR= 46,198; p= 0,019) e relacao braco+perna/tronco (OR=0,00009; p= 0,011); no T2 foram circunferencia abdominal (OR= 1,199; p = 0,025) e HDLc (OR = 0,835; p = 0,015). Conclusao: Em periodo curto de tempo, o grupo CL apresentou significativa redistribuicao de gordura corporal com adiposidade central e alteracoes bioquimicas compativeis com a sindrome lipodistrofica que aumenta o risco cardiovascular desses pacientes
- ItemSomente MetadadadosComposição corporal por bioimpedância e antropometria de idosos longevos(Universidade Federal de São Paulo (UNIFESP), 2016-05-31) Bertolini, Audrey Andrade [UNIFESP]; Cendoroglo, Maysa Seabra Cendoroglo [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Introduction: Aging is associated with changes in body composition in both men and women. Gender differences can impact the functional fitness in elderly with 80 or more years of age, and assessment methods are important to scale these differences. Objective: to compare the assessment of body composition by bioimpedance and anthropometry of physically independent men and women aged 80 years or more. Materials and methods: Individuals above 80 years old independently living in the city of São Paulo were invited to participate in this study through written and verbal communication. The elderly individuals underwent anthropometric evaluation and body composition assessments by bioimpedance. The 2003 criteria of the Pan-American Health Organization (OPAS) was used to assess the nutritional status of the participants. Lean body mass (LBM) variables were identified from the predictive equations of Kyle, Dey, and Valencia. ROC curves were used to demonstrate the sensitivity and specificity of the LBM results by BIA versus equations, and body fat percentage (BFP) results versus tricipital cutaneous fold (TCF) and waist circumference (WC). Results: This study included 221 elderly (72 men and 149 women) aged between 80 and 97 years old. The average values of WC were not different among males 95.3 ± 11 cm and females 90.9 ± 10.8 cm (p = 0.007). Likewise, the averaged values of body mass index (BMI), calf circumference, mid-upper arm muscle circumference (MUAMC) and body fat were similar between the two gender groups. However, TCF and lean body mass (LBM) values showed differences between genders: TCF 18.6 ± 5.7 mm in females and 15.4 ± 5.7 mm in males (p <0.001); LBM 37.0 ± 6.6 kg in females and 45.0 ± 10.4 kg in males (p <0.001). We found a strong correlation between body fat and BMI among women (r = 0.88; p <0.001) and men (r = 0.78; p <0.001), as well as body fat and WC in women (r = 0.76; p <0.001) and also in men (r = 0.79; p <0.001). Calf circumference values showed a stronger correlation to muscle mass in women (r = 0.72; p < 0.001). We also observed that WC and BFP values were high for both genders, except in underweight and eutrophic women. The average LBM index was lower in women with nutritional diagnosis of low weight. The comparison between the LBM by BIA versus predictive equations showed that Dey?s equation is the best estimate of BIA results when applied to eutrophic women. The analysis of skeletal muscle mass index (SMI) revealed that low-weight men showed lower SMI values than women. Conclusion: in order to identify obesity and sarcopenic obesity, even in individuals with normal BMI, it is crucial to consider gender differences and to combine different methods of evaluation, such asskeletal muscle mass (SMM) and SMI.
- ItemSomente MetadadadosDietary Protein Intake in Elderly Women: Association With Muscle and Bone Mass(Sage Publications Inc, 2015-04-01) Genaro, Patricia de Souza; Pinheiro, Marcelo de Medeiros [UNIFESP]; Szejnfeld, Vera Lucia [UNIFESP]; Martini, Ligia Araujo; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)Background: An inadequate food intake, mainly with regard to protein intake, seems to contribute to a reduction of skeletal muscle and bone mass in the elderly. This study was undertaken to evaluate differences in protein intake in women with or without sarcopenia and verify the intake level that is related to a better bone and muscle mass. Methods: Elderly women older than 65 years with sarcopenia (n = 35) and without sarcopenia (n = 165) participated in the study. Assessment of bone mineral density of the lumbar spine and femur was taken, body composition was evaluated by dual-energy x-ray absorptiometry, and an evaluation of protein intake was performed through 3-day dietary records. Results: Muscle, bone, and fat mass was significantly higher in women who had protein intake > 1.2 g/kg/d. A lower intake of essential amino acids in women with sarcopenia was also observed. Protein and energy intake were significant predictors of muscle mass. the presence of osteoporosis was a predictor of muscle strength. in conclusion, the present study demonstrated that in elderly women, an adequate protein intake in terms of quality and quantity, without need of supplementation, could have a positive impact on bone mineral density, lean mass, and skeletal muscle mass.
- ItemAcesso aberto (Open Access)Efeitos da terapia multidisciplinar de longo prazo sobre a composição corporal de adolescentes internados com obesidade severa(Sociedade Brasileira de Pediatria, 2009-06-01) Prado, Wagner Luiz do [UNIFESP]; Siegfried, Alena; Dâmaso, Ana Raimunda [UNIFESP]; Carnier, June [UNIFESP]; Piano, Aline de [UNIFESP]; Siegfried, Wolfgang; Universidade Federal de São Paulo (UNIFESP); Obesity Rehabilitation Centre INSULAOBJECTIVE: To describe the effects of long-term multidisciplinary inpatient therapy on body composition of severely obese adolescents. METHODS: A total of 728 extremely obese adolescents, including 249 boys (aged 15.25±1.56 years) and 479 girls (aged 15.34±1.59 years) received multidisciplinary therapy during a period of 3 to 9 months. The therapy consisted of reduced energy intake, dietetic education, physical exercises and psychological therapy. Body composition was assessed by bioelectrical impedance analysis, and physical capacity was assessed by the multistage cycle ergometer test. Type and duration of each activity were recorded using a daily controlled activity diary. RESULTS: There was a significant decrease (p < 0.05) in body mass (27.84±12.49 kg for boys and 21.60±9.87 kg for girls), body mass index (9.19±3.88 kg/m² for boys and 7.72±3.98 kg/m² for girls) and fat mass. In addition, the percentage of fat free mass increased significantly (p < 0.05) in boys (from 58.8±6.41 to 69.98±7.43%) and in girls (from 51.86±4.96 to 60.04±5.65%). CONCLUSION: Long-term multidisciplinary approach allows significant reduction in severe obesity, preserving growth and percentage of fat free mass.
- ItemSomente MetadadadosEffects of ageing on the energy balance of food-restricted rats(Blackwell Publishing Ltd, 2004-06-01) Passadore, M. D.; Griggio, Mauro Antonio [UNIFESP]; Nunes, M. T.; Luz, J.; Universidade Federal de São Paulo (UNIFESP)Aims: Age can alter energy balance by decreasing the resting metabolic rate. Food restriction can also change energy balance by decreasing energy expenditure as a mechanism of energy conservation. We investigated the influence of food restriction on the energy balance of rats at different ages.Methods: Wistar EPM-1 female rats were used at ages of 3, 9, 15 and 21 months. At each age, two food intake schedules were provided: control (ad libitum) and food restriction (50%). Animals remained under these schedules for 30 days, and throughout this period body weight, food intake, and stool collection were controlled daily. On the 30th day, animals were killed, blood was collected and the carcasses and faeces were processed for analysis by pump calorimetry. Blood glucose, T-3, T-4 and rT(3) levels were determined.Results: Food restriction reduced energy gain and gross food efficiency of animals at different ages, but more so in older animals. Food-restricted rats also had lower energy expenditure than controls. This reduction was about 40% of the energy expenditure of control animals irrespective of age. Water content increased and fat content decreased in the carcass of food-restricted animals. Serum T-3 and T-4 levels were lower in food-restricted animals pointing out to a major role of thyroid hormones in the mechanism of energy conservation exhibited by food-restricted animals.Conclusions: the mechanism of energy conservation takes place in all restricted animals and is very important for survival and for species preservation, mainly in aged animals in which food restriction is frequently aggravated by senescence-related organic disorders.
- ItemSomente MetadadadosEffects of creatine supplementation on body composition and renal function in rats(Lippincott Williams & Wilkins, 2005-09-01) Ferreira, Larissa Gorayb [UNIFESP]; Bergamaschi, Cássia de Toledo [UNIFESP]; Lazaretti-Castro, Marise [UNIFESP]; Heilberg, Ita P. [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Background: the aim of the present study was to evaluate the long-term effects of oral creatine supplementation on renal function and body composition (fat and lean mass) in an experimental model. Methods: Male Wistar rats were supplemented with creatine (2 g(.)kg(-1) of food) for 10 wk in combination with treadmill exercise, 12 m(.)min(-1), 1 h(.)d(-1) (CREAT+EX, N = 12) or not (CREAT, N = 10), and compared with exercised animals without creatine supplementation (EX, N = 7) and CONTROL animals, N = 7. Body composition and bone mineral density (BMD) were determined by dual x-ray absorptiometry and glomerular filtration rate (GFR) and renal plasma flow (RPF) were measured by inulin and paraaminohippurate clearance, respectively. Results: At the end of the study (post), CREAT+EX presented higher lean mass and lower fat mass than CREAT, EX or CONTROL (349.7 +/- 19.7 vs 313.3 +/- 1- 20.3, 311.9 +/- 30.8, 312.4 +/- 21.0 g and 5.7 +/- 2.3 vs 10.0 +/- 3.3, 9.8 +/- 1.5, 10.0 +/- 3.5%, P < 0.05, respectively). Post lean/fat mass ratio was higher than baseline only in CREAT+EX (18.9 +/- 7.2 vs 8.6 +/- 1.8,P < 0.05). Post BMD was significantly higher than baseline in all groups. GFR and RPF were lower in CREAT versus CONTROL (0.5 +/- .1 vs 1.0 +/- 0.1 and 1.5 +/- 0.2 vs 2.4 +/- 0.5 mL(.)min(-1), P < 0.05, respectively). Conclusion: Creatine supplement in combination with exercise increased the proportion of lean mass more than EX or CREAT alone. the use of creatine alone induced an important and significant reduction of both RPF and GFR.
- ItemAcesso aberto (Open Access)Effects of Three-Month Intake of Synbiotic on Inflammation and Body Composition in the Elderly: A Pilot Study(Mdpi Ag, 2013-04-01) Valentini Neto, Joao; Melo, Camila Maria de [UNIFESP]; Lima Ribeiro, Sandra Maria; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)We hypothesize that improvements in the gut microbiota are capable of ameliorating gut permeability and, consequently, reducing systemic inflammation and the risk of frailty. This study aims to evaluate some effects of synbiotic supplementation on inflammatory markers and the body composition of the elderly at risk of frailty. in a double-blind study that lasted three months, 17 elderly individuals fulfilling one frailty criteria (grip strength) were randomly distributed into two groups: SYN (n = 9), daily intake of synbiotic (6 g Frutooligossacarides, 10(8) to 10(9) CFU Lactobacillus paracasei, 10(8) to 10(9) CFU Lactobacillus rhamnosus, 10(8) to 10(9) CFU Lactobacillus acidophilus and 10(8) to 10(9) CFU Bifidobacterium lactis), or placebo (maltodextrin; PLA; n = 8). Subjects were analyzed for anthropometric measurements, bioelectric impedance with vectorial analysis (BIVA), IL-6 and TNF-alpha. A comparison between groups did not show any difference for the variables investigated. in turn, individual analysis of electrical impedance (BIVA) demonstrated that the majority of SYN individuals maintained or improved their tissue hydration, when compared to the PLA group after supplementation. in conclusion, three months of synbiotic supplementation did not promote any significant changes in inflammatory cytokines or body composition, but demonstrated a trend towards a preservation of hydration status in apparently healthy elderly individuals.
- ItemSomente MetadadadosEstimating total body fat using a skinfold prediction equation in Brazilian children(Informa Healthcare, 2012-03-01) Hoffman, Daniel J.; Toro-Ramos, Tatiana; Sawaya, Ana Lydia [UNIFESP]; Roberts, Susan B.; Rondo, Patricia; Rutgers State Univ; Universidade Federal de São Paulo (UNIFESP); Tufts Univ; Universidade de São Paulo (USP)Background: the double burden of obesity and underweight is increasing in developing countries and simple methods for the assessment of fat mass in children are needed.Aim: To develop and validate a new anthropometric predication equation for assessment of fat mass in children.Subjects and methods: Body composition was assessed in 145 children aged 9.8 +/- 1.3 (SD) years from São Paulo, Brazil using dual energy X-ray absorptiometry (DEXA) and skinfold measurements. the study sample was divided into development and validation sub-sets to develop a new prediction equation for FM (PE).Results: Using multiple linear regression analyses, the best equation for predicting FM (R-2 - 0.77) included body weight, triceps skinfold, height, gender and age as independent variables. When cross-validated, the new PE was valid in this sample (R-2 = 0.80), while previously published equations were not.Conclusion: the PE was more valid for Brazilian children that existing equations, but further studies are needed to assess the validity of this PE in other populations.