Navegando por Palavras-chave "attention-deficit hyperactivity disorder"

Agora exibindo 1 - 2 de 2
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Spontaneously Hypertensive Rats: Possible Animal Model of Sleep-Related Movement Disorders
    (Routledge Journals, Taylor & Francis Ltd, 2013-11-01) Esteves, Andrea M.; Lopes, Cleide [UNIFESP]; Frussa-Filho, Roberto [UNIFESP]; Frank, Miriam K.; Cavagnolli, Daniel [UNIFESP]; Arida, Ricardo M. [UNIFESP]; Tufik, Sergio [UNIFESP]; Mello, Marco Tulio de [UNIFESP]; Universidade Estadual de Campinas (UNICAMP); Universidade Federal de São Paulo (UNIFESP)
    Clinical experience suggests that restless legs syndrome (RLS), periodic leg movement (PLM), and attention-deficit hyperactivity disorder (ADHD) may co-occur in both children and adults. the purpose of the present study was to provide an electrocorticography and electromyography evaluation of the spontaneously hypertensive rat (SHR) to investigate the potential of this rat strain as an animal model of RLS-PLM. Initial work focused on evaluating sleep patterns and limb movements during sleep in SHR, having normotensive Wistar rats (NWR) as control, followed by comparison of two treatments (pharmacological-dopaminergic agonist treatment and nonpharmacological-chronic physical exercise), known to be clinically beneficial for sleep-related movement disorders. the captured data strengthen the association between SHR and RLS-PLM, revealing a significant reduction on sleep efficiency and slow wave sleep and an increase on wakefulness and limb movements for the SHR group during the dark period, as compared to the NWR group, effects that have characteristics that are strikingly consistent with RLS-PLM. the pharmacological and nonpharmacological manipulations validated these results. the present findings suggest that the SHR may be a useful putative animal model to study sleep-related movement disorders mechanisms.
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Summaries of plenary, symposia, and oral sessions at the XXII World Congress of Psychiatric Genetics, Copenhagen, Denmark, 12-16 October 2014
    (Lippincott Williams & Wilkins, 2016) Aas, Monica; Blokland, Gabriella A. M.; Chawner, Samuel J. R. A.; Choi, Shing-Wan; Estrada, Jose; Forsingdal, Annika; Friedrich, Maximilian; Ganesham, Suhas; Hall, Lynsey; Haslinger, Denise; Huckins, Laura; Loken, Erik; Malan-Muller, Stefanie; Martin, Joanna; Misiewicz, Zuzanna; Pagliaroli, Luca; Pardinas, Antonio F.; Pisanu, Claudia; Quadri, Giorgia; Santoro, Marcos L. [UNIFESP]; Shaw, Alex D.; Ranlund, Siri; Song, Jie; Tesli, Martin; Tropeano, Maria; van der Voet, Monique; Wolfe, Kate; Cormack, Freida K.; DeLisi, Lynn
    The XXII World Congress of Psychiatric Genetics, sponsored by the International Society of Psychiatric Genetics, took place in Copenhagen, Denmark, on 12-16 October 2014. A total of 883 participants gathered to discuss the latest findings in the field. The following report was written by student and postdoctoral attendees. Each was assigned one or more sessions as a rapporteur. This manuscript represents topics covered in most, but not all of the oral presentations during the conference, and contains some of the major notable new findings reported. (c) 2016 Wolters Kluwer Health, Inc. All rights reserved.