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- ItemSomente MetadadadosAbnormal course of the superficial palmar branch of the radial artery(Springer, 1996-04-01) Olave, E.; Prates, J. C.; Gabrielli, C.; DelSol, M.; Mandiola, E.; UNIV LA FRONTERA; UNIV AUSTRAL CHILE; Universidade Federal de São Paulo (UNIFESP)The structures in the carpal tunnel are the flexor muscle tendons and their sheaths and the median n. Due to the inflexibility of its walls, any swelling of its contents that produces decrease of its volume, may compress the median n, There are many possible causes of nerve compression, such as the presence of arteries in this tunnel [3, 13]. the carpal tunnels of 70 hands of 35 adult cadavers of both sexes, whose age ranged from 23 to 77 years, were studied by dissection, An abnormal course of the superficial palmar branch of the radial a. was found in 2 hands (2.85%). This vascular branch passed through the carpal tunnel, This unusual course of the superficial palmar branch of the radial a. is described with details correlating its presence in the carpal tunnel with the median n.
- ItemSomente MetadadadosDeep palmer arch patterns in Brazilian individuals(Springer, 1999-08-01) Olave, Enrique [UNIFESP]; Prates, José Carlos [UNIFESP]; Univ La Frontera; Universidade Federal de São Paulo (UNIFESP)The deep palmar arch is very important in the blood supply to the hand. Consequently, the radial artery and the deep palmar arch were studied in 60 hands from 30 cadavers of adult Brazilian individuals, of both sexes. The cadavers belong to the Universidade Federal de Sao Paulo, Brazil. The hand arteries were injected with red stained latex neoprene: the deep palmar arch was observed in 59 preparations (98.3%). The arch conformation was classified in two groups, according to the course of the radial artery through the interosseous spaces from the dorsal to the deep palmar region. In group I the radial artery passed through the first interosseous space, and was observed in 51 preparations (85.0%); in group II, the artery passed through the second interosseous space, and was observed in 8 preparations (13.3%). In each group the arches were subdivided according to the number and origin of the deep palmar branch. In group I the arch was formed by the radial artery anastomosing with one deep palmar branch in 41 cases (68.3%), and with two deep palmar branches in 10 cases (16.7%). These branches originated from the ulnar artery, ulnar proper palmar digital artery of the little finger or the common palmar digital artery of the fourth interosseous space. In group II the deep palmar arch was formed by the radial artery anastomosing with one deep palmar branch in 7 cases (11.7%) and in only one case (1.7%) with two deep palmar branches. Knowledge of the arterial variations is very important for surgical procedures in the palmar region.
- ItemSomente MetadadadosThe deep plantar arch in humans: constitution and topography(Springer, 2001-08-01) Gabrielli, C.; Olave, E.; Mandiola, E.; Rodrigues, CFS; Prates, J. C.; Universidade Federal de Santa Catarina (UFSC); Univ La Frontera; Universidade Federal de São Paulo (UNIFESP)The integrity of the various structures within the feet depends on their blood supply. Lesions of the feet often require revascularization, which if successful avoids the need for amputation. To provide greater anatomical detail to aid vascular surgery and imaging, the anatomy and constitution of the deep plantar arch was studied in 50 adult cadaveric feet. the arteries of the foot were injected with red neoprene latex and dissected under magnification. the deep plantar arch, present in all feet, was the result of anastomosis between the deep plantar artery and the deep branch of the lateral plantar artery. the deep plantar artery was predominant in 72% of specimens (Type I arches) and the lateral plantar artery in 22% (Type II), with the contribution being equal in 6% (Type III). the medial plantar artery contributed to the medial segment of the deep plantar arch by its deep branch in 12% of specimens. the distance between the deep plantar arch and each interdigital commissure was generally constant, averaging 29% of total foot length. the deep plantar arch was located in the middle third of the foot in all specimens. being in the distal part of this third in 90%. the deep plantar arch is, therefore formed mainly by the deep plantar artery, a branch of the dorsal artery of foot: its location can be estimated if foot length is known.
- ItemSomente MetadadadosEffect of cholecalciferol treatment on the relaxant responses of spontaneously hypertensive rat arteries to acetylcholine(Lippincott Williams & Wilkins, 1999-10-01) Borges, Antonio Carlos Romao [UNIFESP]; Feres, Teresa [UNIFESP]; Vianna, L. M.; Paiva, Therezinha Bandiera [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)We studied the effect of oral cholecalciferol treatment on the endothelium-dependent vascular relaxation and hyperpolarization induced by acetylcholine (ACh), which is impaired in spontaneously hypertensive rats (SHR). Adult female SHR and normotensive Wistar-Kyoto rat (WKY) controls received 125 mu g of cholecalciferol per kilogram body weight per day for 6 weeks. The responses to ACh of the isolated mesenteric vascular bed and mesenteric artery rings were measured, as well as the smooth muscle cell membrane potential. After cholecalciferol treatment, the systolic blood pressure and basal perfusion pressure of the mesenteric vascular bed of the SHR fell to control levels. The relaxant and hyperpolarizing effects of ACh, which are reduced in SHR, were also brought to control levels after cholecalciferol treatment. These effects of ACh were inhibited by N-omega-nitro-L-arginine in SHR and by apamin in WKY. After cholecalciferol treatment, SHR hyperpolarizing responses showed the same inhibition pattern as those of WKY. This indicates that, after cholecalciferol treatment, SHR vascular mesenteric preparation responses to ACh are mediated by endothelium-derived hyperpolarizing factor, which induces activation of Ca2+-dependent K+ channels, as in WKY. In untreated SHR, the ACh-mediated response is entirely due to ACh acting via the release of nitric oxide.
- ItemAcesso aberto (Open Access)Effect of sildenafil in cavernous arteries of patients with erectile dysfunction(Sociedade Brasileira de Urologia, 2003-08-01) Claro, Joaquim A [UNIFESP]; Ximenes, Sergio Felix [UNIFESP]; Nardozza Júnior, Archimedes [UNIFESP]; Andrade, Enrico [UNIFESP]; Messina, Leonardo [UNIFESP]; Srougi, Miguel [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)INTRODUCTION: Sildenafil citrate is a type 5 phosphodiesterase inhibitor, which has demonstrated excellent results in the treatment of erectile dysfunction. The effect of sildenafil citrate in the cavernous arteries of patients with erectile dysfunction has not been established yet. The objective of this study was to assess the effect of sildenafil citrate in the cavernous arteries of patients with erectile dysfunction, following an intracavernous injection of alprostadil. MATERIALS AND METHODS: 29 male patients, with mean age of 53.8 years (32 to 75 years), were prospectively evaluated. The mean time with complaint of erectile dysfunction was 50.5 months (6 to 168 months). Each patient was his own control. Patients underwent a measurement of peak systolic velocity before and after use of sildenafil citrate associated with 5 micrograms of alprostadil, through ultrasonic velocitometry Knoll/MIDUS® system. In the interval between measurements, approximately 15 days, patients used 3 tablets of sildenafil at home with their partners. RESULTS: Using only 5 mcg of alprostadil, average peak systolic velocity was 23.9 cm/s, and when associated to 50 mg of sildenafil it was 24.8 cm/s. Despite the increase in the flow rate caused by sildenafil, the difference was not statistically significant, Zcalculated = - 0.695 NS (Wilcoxon test). Twenty one of the 29 patients (72.4%) showed global improvement in sexual performance with the use of sildenafil citrate at home. There was not a statistically significant correlation between the global response to sildenafil citrate and the increase in the peak systolic velocity. CONCLUSION: We concluded that, even though the use of 50 mg of sildenafil citrate associated with 5 mcg of alprostadil provides an increase in the peak systolic velocity of the cavernous arteries, there was no statistic difference in relation to alprostadil alone. There was no correlation between the global response to sildenafil and the increase in the peak systolic velocity
- ItemSomente MetadadadosMedian artery and superficial palmar branch of the radial artery in the carpal tunnel(Scandinavian University Press, 1997-03-01) Olave, Enrique [UNIFESP]; Prates, José Carlos [UNIFESP]; Gabrielli, Carla [UNIFESP]; Pardi, Paulo [UNIFESP]; UNIV LA FRONTERA; Universidade Federal de São Paulo (UNIFESP)In the carpal tunnel there are the flexor muscle tendons, their sheaths, and the median nerve. Because its walls are inflexible, any thickening of its components that reduce its area may compress the median nerve. There are many reasons for nerve compression, including persistence of the median artery into adult life. We dissected the arteries in the carpal tunnel of 102 hands of 51 adult cadavers of both sexes, age range 23-77 years, and injected latex into 42 hands. In the carpal tunnel we sought the median artery and the superficial palmar branch of the radial artery. We found the median artery in 23 of 102 cases (23%), and its calibre ranged from 0.7 to 2.7 mm, mean (SD) 1.6 (0.5) mm. In 16 cases it made up part of the superficial palmar arch. The superficial palmar branch of the radial artery was partly responsible for the distal irrigation of the hand in 48 cases (47%); and in three hands (3%) it passed through the carpal tunnel. The external diameters of these vessels were 1.8, 1.9, and 1.8 mm, respectively. These arteries might cause compression of the median nerve and consequently the carpal tunnel syndrome.
- ItemSomente MetadadadosPerforating branches: Important contribution to the formation of the dorsal metacarpal arteries(Scandinavian University Press, 1998-06-01) Olave, Enrique [UNIFESP]; Prates, José Carlos [UNIFESP]; Gabrielli, Carla [UNIFESP]; Mandiola, Eduardo; Univ La Frontera; Universidade Federal de São Paulo (UNIFESP); Univ Austral ChileThe perforating branches that originate from the deep palmar arch of the hand have been studied to provide a complete anatomical description of these vessels and assess their importance in the blood collateral pathway of the hand. We injected latex into the arteries of 50 cadaveric hands of 25 adults of both sexes, all of Brazilian origin. These were dissected under a stereoscopic microscope. The perforating branch of the second interosseous space originated from the deep palmar arch in 80% of the cases, and it corresponded to the radial artery passing through the second space in 16%; the one of the third interosseous space originated from the deep palmar arch in 76% of the cases and from the palmar metacarpal artery of the third interosseous space in 16%; the one of the fourth interosseous space originated from the deep palmar arch in half the cases, from the deep palmar branch of the ulnar artery in 14%, and from the palmar metacarpal artery of this space in 18%. The perforating branch of the second space anastomosed with the second dorsal metacarpal artery (DMA) in 60% of the cases and formed it in 10%; the one of the third space anastomosed with the third DMA in 20% and formed it in 64%; the one of the fourth space anastomosed with the fourth DMA in 8% and formed it in 78%. These vessels are an important anastomotic pathway between the dorsal carpal network and the deep arteries of the hand and an important in the supply to the dorsum.