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- ItemAcesso aberto (Open Access)Adolescência através dos séculos(Instituto de Psicologia, Universidade de Brasília, 2010-06-01) Schoen-ferreira, Teresa Helena [UNIFESP]; Aznar-farias, Maria [UNIFESP]; Silvares, Edwiges Ferreira De Mattos; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)Contemporary western society has extended the period of adolescence, which is no longer seen as a preparation for adult life, but began to make sense of itself as part of the human lifecycle. The present article aims to describe how adolescents have been seen and treated, from antiquity to the present days, as reported by literary or philosophical texts and scientific studies. The bibliographic material on adolescence is characterized by three distinct stages: description of behavior, personal adjustment, and relationship patterns; problem solving through scientific knowledge; and the positive development of the individual, considering adolescents as the future of mankind.
- ItemAcesso aberto (Open Access)O adolescente e suas representações sociais: apontamentos sobre a importância do contexto histórico(IMS-UERJ, 2013-09-01) Quiroga, Fernando Lionel [UNIFESP]; Vitalle, Maria Sylvia de Souza [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)This study aims to discuss the modes of social representation of adolescence. Scientific tradition, especially from Erikson (1976), favored the social representation according to which adolescence is a period of transition between childhood and adulthood, ie, a period marked by instability, crisis and turbulence whose main characteristic is manifested by the loss of childhood and the beginning of adult life. The discussion presented here derives from the assumption that, when the adolescent universe acquires social status of legitimacy, which can be seen through the media and social representation, then adolescence is no longer that period of instability and crisis; unfamiliar period which only sense is to reach adulthood. Adolescence, as it is represented in its own socially symbolic construction, can no longer be seen only as an interface, but has legitimated its own social space.
- ItemSomente MetadadadosAre reasons for the first use of drugs and family circumstances predictors of future use patterns?(Elsevier B.V., 2002-01-01) De Micheli, D.; Formigoni, MLOS; Universidade Federal de São Paulo (UNIFESP)The objective of this study was to investigate whether the level of drug dependence in adolescents can be predicted by any of the following factors: the reasons to which the first use or non-use of drugs is attributed, living arrangements, economic situation, family history of alcohol use, or school delay. 213 Brazilian adolescents were classified according to DSM-III-R criteria as: 71 non-drug-dependent users (Group 1), 71 lightly/moderately dependent users (Group 2), and 71 severely dependent users (Group 3). Logistic regression identified the following predictors of current drug use patterns: low economic level, school delay, living only with the mother, having a poor/bad family relationship, and influence of friends, pleasure seeking, or curiosity as reasons for initial drug use. Among Groups I and 2, never felt like trying, fear of dying from an overdose, and religious reasons were the main reasons for not using other drugs. School delay and troubled family relationships were important predictors of current drug dependence, and pleasure seeking was a prominent reason for initial drug use. This suggests that drug use prevention should not simply focus on reducing drug availability but also on helping young people to develop good family/peer relationships and finding healthy ways to enjoy themselves. (C) 2001 Elsevier B.V. All rights reserved.
- ItemAcesso aberto (Open Access)Atitudes alimentares e imagem corporal em meninas adolescentes de ascendência nipônica e caucasiana em São Paulo (SP)(Sociedade Brasileira de Pediatria, 2009-04-01) Sampei, Miriam Akemi [UNIFESP]; Sigulem, Dirce Maria [UNIFESP]; Novo, Neil Ferreira [UNIFESP]; Juliano, Yara; Colugnati, Fernando Antonio Basile [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade de Santo Amaro; Instituto de Pesquisas em Tecnologia e InovaçãoOBJECTIVE: Despite investigations into the rapid increase in eating disorders across diverse ethnic groups, conclusions concerning ethnicity and eating disorders are contradictory. The objective of the present study was to investigate eating attitudes in ethnic Japanese and Caucasian adolescents in Brazil. The influence of body mass index (BMI), menarche and social-affective relationships on the development of eating disorders was also assessed. METHODS: Questionnaires evaluating the incidence of eating disorders and the influence of social-affective relationships were applied to 544 Japanese-Brazilian and Caucasian adolescent girls: 10 to 11-year-old Japanese-Brazilian (n = 122) and Caucasian (n = 176) pre-menarcheal adolescents, and 16 to 17-year-old Japanese-Brazilian (n = 71) and Caucasian (n = 175) post-menarcheal adolescents. RESULTS: Caucasian girls obtained higher scores on the Eating Attitudes Test (EAT-26), showed greater body image dissatisfaction, dieted more often and had more diet models introduced by their mothers and peers than the Japanese-Brazilian girls. CONCLUSION: The Caucasian adolescents overall appeared to be more sensitive to aesthetic and social pressures regarding body image than the Japanese adolescents. The high incidence of EAT-26 scores above 20 in the Caucasian pre-menarcheal group indicates that individual body image concerns are developing at an earlier age. Multiple logistic regression revealed several associations between mother-teen interactions and the development of abnormal eating attitudes.
- ItemSomente MetadadadosAyahuasca in adolescence: A neuropsychological assessment(Haight-ashbury Publ, 2005-06-01) Doering-Silveira, Evelyn; Lopez, Enrique; Grob, Charles S.; Rios, Marlene Dobkin de; Alonso, Luisa K.; Tacla, Cristiane; Shirakawa, Itiro; Bertolucci, Paulo H.; Da Silveira, Dartiu X.; Universidade Federal de São Paulo (UNIFESP); Univ Calif Los Angeles; Harbor UCLA Med Ctr; Univ Calif Irvine; Universidade de Brasília (UnB)The purpose of the study was to evaluate neuropsychologically adolescents who use ayahuasca in a religious context. A battery of neuropsychological tests was administered to adolescents who use ayahuasca. These subjects were compared to a matched control group of adolescents who did not use ayahuasca. The controls were matched with regards to sex, age, and education. The neuropsychological battery included tests of speeded attention, visual search, sequencing, psychomotor speed, verbal and visual abilities, memory, and mental flexibility. The statistical results for subjects from matched controls on neuropsychological measures were computed using independent t-tests. Overall, statistical findings suggested that there was no significant difference between the two groups on neuropsychological measures. Even though, the data overall supports that there was not a difference between ayahuasca users and matched controls on neuropsychological measures, further studies are necessary to support these findings.
- ItemSomente MetadadadosAyahuasca in adolescence: A preliminary psychiatric assessment(Haight-ashbury Publ, 2005-06-01) Da Silveira, D. X.; Grob, Charles S.; Rios, Marlene Dobkin de; Lopez, Enrique; Alonso, Luisa K.; Tacla, Cristiane; Doering-Silveira, Evelyn; Universidade Federal de São Paulo (UNIFESP); Harbor UCLA Med Ctr; Univ Calif Irvine; Univ Calif Los Angeles; Universidade de Brasília (UnB)Ayahuasca is believed to be harmless for those (including adolescents) drinking it within a religious setting. Nevertheless controlled studies on the mental/ psychiatric status of ritual hallucinogenic ayahuasca concoction consumers are still lacking. In this study, 40 adolescents from a Brazilian ayahuasca sect were compared with 40 controls matched on sex, age, and educational background for psychiatric symptomatology. Screening scales for depression, anxiety, alcohol consumption patterns (abuse), attentional problems, and body dysmorphic disorders were used. It was found that, compared to controls, considerable lower frequencies of positive scoring for anxiety, body dismorphism, and attentional problems were detected among ayahuasca-using adolescents despite overall similar psychopathological profiles displayed by both study groups. Low frequencies of psychiatric symptoms detected among adolescents consuming ayahuasca within a religious context may reflect a protective effect due to their religious affiliation. However further studies on the possible interference of other variables in the outcome are necessary.
- ItemSomente MetadadadosBody mass index and body composition in relation to sexual maturation(Freund Publishing House Ltd, 2008-02-01) Castilho, Silvia Diez; Cocetti, Monize; Barros Filho, Antonio de Azevedo; Universidade Federal de São Paulo (UNIFESP); Univ Catolica CampinasAim: To assess body mass index. (BMI) in relation to sexual maturation and verify how fat-free mass (FFM) and fat mass (FM) contribute to its increase.Methods: 1,275 White adolescents (656 girls and 619 boys), aged 9 to 18 years, were evaluated according to Tanner stages. FFM and FM were calculated by triceps and subscapular skinfold measurements and leg-to-leg bioelectrical impedance. BMI-for-maturation was distributed into percentiles. Fat-free mass index (FFMI) and body fat mass index (BFMI) were calculated based on BMI 50(th) percentile values.Results: During maturation, as BMI increases, girls gain FFMI (13.3 kg/m(2) at 131 and 15.8 kg/m(2) at 135) and BFMI (3.7 kg/m(2) at B1 and 5.7 kg/m(2) at B5) - proportionally more fat - while boys gain FFMI (14.3 kg/m(2) at G1 and 17.9 kg/m(2) at G5) and lose BFMI (4.8 kg/m(2) at G1 and 3.2 kg/m(2) at G5).Conclusion: These data suggest that FFMI and BFMI-for-maturation should be assessed in adolescents monitored for overweight and obesity.
- ItemAcesso aberto (Open Access)Comparação do perfil lipídico, pressão arterial e aspectos nutricionais em adolescentes, filhos de hipertensos e de normotensos(Sociedade Brasileira de Cardiologia - SBC, 2004-02-01) Elias, Maria Cristina [UNIFESP]; Bolívar, Max Samuel Mattos [UNIFESP]; Fonseca, Francisco Antonio Helfenstein [UNIFESP]; Martinez, Tania Leme Da Rocha [UNIFESP]; Angelini, Japy [UNIFESP]; Ferreira, Celso [UNIFESP]; Kasinski, Nelson [UNIFESP]; De Paola, Angelo Amato Vincenzo [UNIFESP]; Carvalho, Antonio Carlos [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)OBJECTIVE: To compare blood pressure, lipid profile, food intake, and anthropometric data of adolescents with or without a familial history of hypertension. METHODS: Forty-three adolescents from both sexes were assessed, with ages ranging from 11 to 18 years old. Twenty had hypertensive parents, and 23 had normotensive parents. The following variables were examined: blood pressure, food intake, anthropometric data, lipid profile, and the results of following dietary guidelines (American Heart Association). RESULTS: The offspring of hypertensive parents had greater baseline systolic blood pressure (109 ± 3 vs. 99 ± 2 mm Hg, P=0.01), diastolic blood pressure (68 ± 2 vs. 62 ± 2 mm Hg, p=0.04), greater TC/HDL-C ratio (4.1 ± 0.3 vs. 3.2 ± 0.2, P<0.01), and greater LDL/HDL-C (2.7 ± 0.2 vs. 1.9 ± 0.1, P<0.01), and smaller values of HDL-C (43 ± 2 vs.53 ± 2 mg/dL, P<0.005). Dietary intake and anthropometric measures assessed did not differ between the groups. Even though dietary intervention resulted in reductions in body mass index (21.0± 1.2 vs. 20.1 ± 1.1 kg/m², P<0.01), it did not change dyslipidemia present in the offspring of hypertensive individuals. CONCLUSION: Increased blood pressure levels and less favorable lipid profiles are found among offspring of hypertensive parents, where low levels of HDL-C were the most relevant finding regardless of anthropometric or nutritional variables.
- ItemSomente MetadadadosCompetência, problemas psicológicos e comportamentos pró-sociais em adolescentes abrigados(Universidade Federal de São Paulo (UNIFESP), 2013-02-27) Fernandes, Amanda Oliveira [UNIFESP]; Oliveira-Monteiro, Nancy Ramacciotti de [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Purpose: this study aimed to evaluate the psychological conditions of sheltered adolescents in terms of perception of their condition of sheltered, competences levels, psychological problems and prosocial behavior. Methods: 61 adolescents were evaluated, 11 to 18 years, residents of shelters of Baixada Santista (SP), 34 girls and 27 boys. The individuals were evaluated using the following instruments: interview of free speech autobiographical, questionnaire, YSR - Youth Self-Report for Ages 11-18 and EMPA - Measurement Scale Pro-Sociality. Results: the analysis of the results was made by subgroups of age (11 -14 years / 15-18 years), sex and time in shelters (until two years and more than two years). Findings indicated negative perception of the condition of shelters, especially by adolescents with less time in shelters. On the other hand, were present in the microsystem of these adolescents protective references, through indicators of help reception arising out employees of the shelters, especially in situations of illness. Within the area of competences in relation to the activities, girls showed no clinical ranges, especially the oldest and longer time in shelters. In general, adolescents showed clinical levels for total competence. Prosocial behaviors of care, restricted to friends, were shown primarily in adolescents with less time in shelters. The girls reported, in general, more prosocial behavior than boys. The adolescent in the study indicated a strong tendency to the difficulty of sharing value and personal objects, and empathy. Internalizing and externalizing psychological problems in clinical ranges, also performed in the sample, especially in older girls. Difficulties in important microsystems, such as family and school, were listed in the adolescents studied. Final considerations: This study highlights the need for expanding and deepening of research on positive development of children and adolescents living in shelters, in order to support appropriate proposals to the development of int ernal and external resources of adolescents in their main contexts of interaction, such as shelter, school and family.
- ItemAcesso aberto (Open Access)A construção da identidade em adolescentes: um estudo exploratório(Programa de Pós-graduação em Psicologia, Universidade Federal do Rio Grande do Norte, 2003-04-01) Schoen-ferreira, Teresa Helena [UNIFESP]; Aznar-farias, Maria [UNIFESP]; Silvares, Edwiges Ferreira De Mattos; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)According to Erikson's psychosocial theory, the most important task during adolescence is identity construction. Based on this assertion, this study, undertaken with 25 high school students (15 to 17 years old), compared the Groningen Identity Development Scale (GIDS), a identity evolution scale, with the Youth Self-Report (YSR), a screening mental problems checklist. Most of the teenagers were on two initial identity phases: diffusion and foreclosure. A significant relationship between low commitment and behavior problems was also found.
- ItemAcesso aberto (Open Access)Consumo de substâncias psicoativas em uma amostra de adolescentes e sua relação com o comportamento sexual(Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro, 2013-06-01) Miozzo, Luciane; Dalberto, Edson Ricardo; Silveira, Dartiu Xavier da [UNIFESP]; Terra, Mauro Barbosa [UNIFESP]; Universidade Federal de Ciências da Saúde de Porto Alegre Centro de Estudos José de Barros Falcão; Secretaria de Saúde de Serafina Corrêa; Universidade Federal de São Paulo (UNIFESP); UFCSPA Departamento de Clínica MédicaOBJECTIVE: To evaluate the consumption of psychoactive substances and the pattern of sexual behavior in high school students in the city of Serafina Corrêa - RS, with a population of approximately 15,000 inhabitants. METHOD: The sample of this cross-sectional study consisted of all students of both sexes who were attending high school in the city. Questionnaires were used to check the socio-demographic variables, sexual behavior, and drug use. RESULTS: The sample consisted of 453 students of which 261 (57.62%) were female. The drug most often used was alcohol (82.34%), followed by tobacco (12.58%), marijuana (6.62%), and cocaine (5.30%). Regarding the sexual behavior of adolescents, it was observed that 247 (54.5%) reported having had sexual intercourse. We found an association between the adolescent having already used drugs in general (p < 0.001), alcohol (p < 0.001), or smoking (p = 0.023) and having had sexual intercourse. CONCLUSION: The study provides information on the use of drugs and characteristics of sexual behavior of adolescents of this city and may be useful for developing an intervention program to reduce risk factors for drug addiction, including education for the promotion of health.
- ItemAcesso aberto (Open Access)Could Low Birth Weight be Associated with Cardiovascular Disease in Adolescence?(Federacao Brasileira Soc Ginecologia & Obstetricia-Febrasgo, 2016) dos Santos Alves, Priscila de Jesus; Araujo Junior, Edward [UNIFESP]; Pinto Teixeira Henriques, Ana Cileia; Costa Carvalho, Francisco HerlanioPurpose Previous studies have shown that low birth weight (LBW) is associated with cardiovascular risk in late adulthood. Recent studies in adolescents suggest that modifiable factors may have greater influence on increased cardiovascular risk. This study aims to investigate the association between LBW and changes in anthropometric and biochemical risk factors during adolescence in a population with low average socioeconomic status. Methods In a retrospective double cohort, data of birth weight were extracted from hospital records of children born on the same day between 1992 and 2002. According to the World Health Organization, we classified the children as having LBW or normal birth weight. A total of 172 subjects among children, adolescents and adults were researched. We measured anthropometric and clinical data, lipid profile and glucose after an overnight fasting. The low and normal weight groups were compared using Mann-Whitney U, Fischer exact, Chi-square (chi 2) and Student's t tests. Results Pregnant women with preeclampsia delivered more newborns with LBW (p < 0.001). Anthropometric and clinical parameters were similar between groups. No differences were found in the family history of cardiovascular diseases (p = 0.1), family incomes (p = 0.8) and maternal school education (p = 0.8) between groups. Conclusion In this study, LBW did not increase cardiovascular disease risk factors in adolescents. We observed absence of association between low birth weight and poor health outcomes among adolescents with low socioeconomic status from an urban city in the Brazilian northeast.
- ItemSomente MetadadadosCross-sectional study of abnormal amygdala development in adolescents and young adults with bipolar disorder(Elsevier B.V., 2004-09-15) Chen, B. K.; Sassi, R.; Axelson, D.; Hatch, J. P.; Sanches, M.; Nicoletti, M.; Brambilla, P.; Keshavan, M. S.; Ryan, N. D.; Birmaher, B.; Soares, J. C.; Univ Texas; Univ Pittsburgh; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP); IRCCS; S Texas Vet Hlth Care SystBackground: in vivo imaging studies in adult bipolarpatients have suggested enlargement of the amygdala. It is not known whether this abnormality is already present early in the illness course or whether it develops later in life. We conducted a morphometric MRI study to examine the size of specific temporal lobe structures in adolescents and young adults with bipolar disorder and healthy control subjects, as well as their relationship with age, to examine possible neurodevelopmental abnormalities.Methods: Subjects included 16 DSM-IV bipolarpatients (16 +/- 3 years) and 21 healthy controls (mean age SD = 17 +/- 4 years). Measures of amygdala, bippocampus, temporal gray matter, temporal lobe, and intracranial volumes (ICV) were obtained.Results: There was a trend to smaller left amygdala volumes inpatients (mean volumes +/- SD = 1.58 +/- .42 mL) versus control subjects (1.83 +/- .4 mL; F = 3.87, df = 1,32, p =.06). Bipolar patients did not show significant differences in right or left bippocampus, temporal lobe gray matter, temporal lobe, or right amygdala volumes (analysis of covariance, age, gender, and JCV as covariates, p >.05) compared with healthy control subjects. Furthermore, there was a direct correlation between left amygdala volumes and age (r =.50, p =.047) in patients, whereas in healthy controls there was an inverse correlation (r = -. 48, p =.03).Conclusions: the direct correlation between left amygdala volumes and age in bipolar patients, not present in healthy control subjects, may reflect abnormal developmental mechanisms in bipolar disorder,
- ItemAcesso aberto (Open Access)Dermatomiosite juvenil e linfoma de Hodgkin: uma rara associação(Sociedade Brasileira de Reumatologia, 2007-12-01) Cavalcanti, André [UNIFESP]; Terreri, Maria Teresa Ramos Ascensão [UNIFESP]; Sallum, Adriana Maluf Elias; Marie, Suely Kazue Nagahashi; Luisi, Flávio [UNIFESP]; Hilário, Maria Odete Esteves [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)Dermatomyositis (DM) in adults is frequently associated with cancer. In contrast, during childhood juvenile dermatomyositis (JDM) is predominantly idiopathic and its association with neoplasia is rare and based only in case reports. Although rare, the presence of neoplasia in JDM patients must always be suspected in face of atypical clinical manifestations and uncommon laboratorial findings. We describe and discuss a case of JDM and Hodgkin disease in an adolescent.
- ItemSomente MetadadadosEffect of Calcium Intake, Tennis Playing, and Body Composition on Bone-Mineral Density of Brazilian Male Adolescents(Human Kinetics Publ Inc, 2008-10-01) Juzwiak, Claudia Ridel [UNIFESP]; Amancio, Olga Maria Silverio [UNIFESP]; Vitalle, Maria Sylvia de Souza [UNIFESP]; Szejnfeld, Vera Lucia [UNIFESP]; Pinheiro, Marcelo de Medeiros [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)In this prospective, cross-sectional study male adolescent tennis players (44) and nonathletic controls (32) were evaluated to determine the effects of physical activity. dietary nutrient intakes. sexual maturation, and body composition oil bone-mineral density (BMD). Dietary nutrient intakes and physical activity expenditure were estimated by 4-d diaries. Total body composition. bone-mineral content (BMC), and BMD (L1-L4, femur, and nondominant forearm) were assessed by dual-energy X-ray absorptiometry. Tennis players had significantly greater lean body mass (mean [SEM] 50.6 [1.6] kg vs. 45.1 [1.7] kg, p = .022). trochanter BMD (1.0 [0.02] 1 g/cm(2) vs. 0.9 [0.03] g/cm(2), p = .032), and dominant forearm BMC (173.7 [7.4] vs. 146.5 [9.3] g) but lower BMD in the nondominant forearm (0.7 [0.02] g/cm(2) vs. 0.8 [0.03] g/cm(2), p = .028). Daily average calcium intake was below the recommendation in both groups. No correlation was found between BMD and calcium intake and exercise. Lean body mass was the best predictor of BMD and BMC for both tennis players and controls (R-2 = .825,.628, and .693 for L1-L4. total femur, and nondominant forearm. respectively). Based oil these results the authors conclude that lean body, mass is the best Predictor of BMD and BMC for both tennis players and others. Tennis exerts it site-specific effect, and training should focus Oil ways minimize this effect. Although calcium intake showed no effect on BMD, nutrition education for young athletes should focus on promoting a balanced diet, providing energy and nutrients in adequate amounts.
- ItemSomente MetadadadosHope matters to the glycemic control of adolescents and young adults with type 1 diabetes(Sage Publications Ltd, 2015-05-01) Santos, Fabio R. M. [UNIFESP]; Sigulem, Daniel [UNIFESP]; Areco, Kelsy C. N. [UNIFESP]; Gabbay, Monica Andrade Lima [UNIFESP]; Dib, Sergio A. [UNIFESP]; Bernardo, Viviane [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)This study investigated the association of hope and its factors with depression and glycemic control in adolescents and young adults with type 1 diabetes. A total of 113 patients were invited to participate. Significant negative correlations were found between hope and HbA1c and also between hope and depression. Hope showed a significant association with HbA1c and depression in the stepwise regression model. Among the hope factors, inner positive expectancy was significantly associated with HbA1c and depression. This study supports that hope matters to glycemic control and depression. Intervention strategies focusing on hope should be further explored.
- ItemSomente MetadadadosInflammation, neurotrophism and oxidative stress and childhood psychopathology in a large community sample(Wiley, 2016) Cunha, G. R. [UNIFESP]; Asevedo, E. [UNIFESP]; Mansur, R. B. [UNIFESP]; Zugman, A. [UNIFESP]; Pan, P. M. [UNIFESP]; Gadelha, A. [UNIFESP]; Belangero, S. I. [UNIFESP]; Rizzo, L. B. [UNIFESP]; Coelho, R.; Stertz, L.; Cogo-Moreira, H. [UNIFESP]; Grassi-Oliveira, R.; Teixeira, A. L.; Kauer-Sant'Anna, M.; Mari, J. J. [UNIFESP]; Miguel, E. C.; Bressan, R. A. [UNIFESP]; Brietzke, E. [UNIFESP]Objective: To investigate the association between peripheral biomarkers and child psychopathology in a large community sample. Method: A total of 625 aged 6- to 13-year old subjects were recruited from a community school-based study. Psychopathology was assessed using the Child Behaviour Checklist (CBCL). Psychiatric diagnosis was evaluated using the Development and Well-Being Assessment. The following biomarkers were examined in peripheral blood: brain-derived neurotrophic factor, cytokines (IL-2, IL-4, IL-6, IL-10, IL-17, IFN-g, and TNF-alpha), chemokines (eotaxin/CCL11, IP-10, MCP-1), cytokine receptors (sTNFR1 and sTNFR2), and the oxidative stress marker TBARS. Results: We found significant associations between sTNFR2, eotaxin/CCL11 and CBCL total score, as well as with specific dimensions of psychopathology. There were different patterns of association between these biomarkers and psychological and behavioural symptoms in children with and without a mental disorder. TBARS, IL-6 and MCP-1 were more specific to some clusters of symptoms in children with a psychiatric diagnosis. Conclusion: Our data support the potential use of biomarkers, especially those involved in immune-inflammatory pathways, in investigating neurodevelopmental psychopathology. Their association with different dimensions of symptoms might be of useful when analyzing illness severity and clusters of symptoms within specific disorders.
- ItemSomente MetadadadosInflammation, neurotrophism and oxidative stress and childhood psychopathology in a large community sample(Wiley, 2016) Cunha, G. R. [UNIFESP]; Asevedo, E. [UNIFESP]; Mansur, R. B. [UNIFESP]; Zugman, A. [UNIFESP]; Pan, P. M. [UNIFESP]; Gadelha, A. [UNIFESP]; Belangero, S. I. [UNIFESP]; Rizzo, L. B. [UNIFESP]; Coelho, R.; Stertz, L.; Cogo-Moreira, H. [UNIFESP]; Grassi-Oliveira, R.; Teixeira, A. L.; Kauer-Sant'Anna, M.; Mari, J. J. [UNIFESP]; Miguel, E. C.; Bressan, R. A. [UNIFESP]; Brietzke, E. [UNIFESP]Objective: To investigate the association between peripheral biomarkers and child psychopathology in a large community sample. Method: A total of 625 aged 6- to 13-year old subjects were recruited from a community school-based study. Psychopathology was assessed using the Child Behaviour Checklist (CBCL). Psychiatric diagnosis was evaluated using the Development and Well-Being Assessment. The following biomarkers were examined in peripheral blood: brain-derived neurotrophic factor, cytokines (IL-2, IL-4, IL-6, IL-10, IL-17, IFN-g, and TNF-alpha), chemokines (eotaxin/CCL11, IP-10, MCP-1), cytokine receptors (sTNFR1 and sTNFR2), and the oxidative stress marker TBARS. Results: We found significant associations between sTNFR2, eotaxin/CCL11 and CBCL total score, as well as with specific dimensions of psychopathology. There were different patterns of association between these biomarkers and psychological and behavioural symptoms in children with and without a mental disorder. TBARS, IL-6 and MCP-1 were more specific to some clusters of symptoms in children with a psychiatric diagnosis. Conclusion: Our data support the potential use of biomarkers, especially those involved in immune-inflammatory pathways, in investigating neurodevelopmental psychopathology. Their association with different dimensions of symptoms might be of useful when analyzing illness severity and clusters of symptoms within specific disorders.
- ItemSomente MetadadadosINFLUENCE OF PUBERTAL STAGE IN CUT OFF VALUES OF WAIST CIRCUMFERENCE ASSOCIATED TO ALTERED ANTHROPOMETRIC VARIABLES AND BLOOD PRESSURE AS CARDIOMETABOLIC RISK MARKERS IN BRAZILIANS ADOLESCENTS(Karger, 2017) dos Santos, Alves Ivete; Passos, Maria Aparecida [UNIFESP]; Ganen, Aline; Sampaio, Isa [UNIFESP]; Fisberg, Mauro [UNIFESP]
- ItemSomente MetadadadosInstrumentos de inquérito dietético utilizados na avaliação do consumo alimentar em adolescentes: comparação entre métodos(Archivos Latinoamericanos Nutricion, 2007-03-01) Barbosa, Kiriaque Barra Ferreira; Rosado, Lina Enriqueta Frandsen Paez de Lima [UNIFESP]; Franceschini, Sylvia do Carmo Castro [UNIFESP]; Priore, Silvia Eloiza [UNIFESP]; Universidade Federal de Viçosa (UFV); Universidade Federal de São Paulo (UNIFESP)Given the difficulties surrounding evaluating food consumption, specifically during adolescence, the goal of the present study was to compare different dietary assessment instruments used for this age group. The study was carried out with a group of 60 female adolescents between 14 and 18 years of age. Three repetitions of 24-Hour Recall, three-day Dietary Records and Purchase List of the adolescents and their families were collected. The 24 Hour Recall and Dietary Records had good repeatability, allowing to infer that only one application of one of these instruments was capable of reflecting the ingestion average (or median) of the study population group. The Purchase List allowed us to know the food availability within the context of the individual's conditions. All dietary assessment instruments may contain errors, therefore the choice of the most adequate method must rely on the objectives of the study being developed, as well as the study population.