Navegando por Palavras-chave "Ultrasound"

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    Acurácia dos parâmetros ultrassonográficos na predição de malignidade dos nódulos tireoidianos com citologia indeterminada. Revisão sistemática e metanálise
    (Universidade Federal de São Paulo (UNIFESP), 2021) Takaki, Juliana De Oliveira [UNIFESP]; Iared, Wagner [UNIFESP]; Universidade Federal de São Paulo
    Context: Thyroid nodules are a common clinical condition. Its prevalence varies according to the mode of detection and increases with age, ranging from 2% to 6% when populations are examined clinically (by palpation) and reaches 68% when evaluated by ultrasonography (US), with approximately 1 malignant nodule. out of 20 clinically detected nodules. The evaluation of the thyroid nodule has a critical role in the identification of potentially malignant lesions and in making appropriate decisions, being (US) the first diagnostic tool for its investigation. The morphological characteristics of the detected nodules define the degree of risk, determining in which the fine needle aspiration puncture (FNAB) should be performed. However, FNAB is characterized by a gray area of diagnosis in which the indeterminate classification prevents a distinction between benign and malignant lesions and its uncertain malignancy risk always leads to insecurity in the assertive treatment planning. Most lesions with indeterminate cytology (up to 70%) are operated on and subsequently shown to be benign. Therefore, the improved knowledge about risk factors for malignancy, such as suspicious ultrasound characteristics, can improve the diagnostic and therapeutic approach, so that patients with lower risk disease or benign nodules are not submitted to unnecessary invasive procedures. Method: Systematic review and meta-analysis of accuracy studies of six ultrasound patterns (solid composition, hypoechogenic and markedly hypoechoic texture, irregular margins, microcalcifications and a higher than wide shape) in the prediction of malignancy of thyroid nodules with undetermined cytology. Sensitive bibliographic research carried out in the following databases: Cochrane Library, MEDLINE, PUBMED, EMBASE, LILACS, manual search, without language or date restriction, using words, descriptors (MeSH) and their synonyms. Assessment of the risk of bias and applicability and quality by QUADAS 2 (Quality Assessment of Diagnostic Accuracy Studies). The patterns of sensitivity, specificity, positive and negative predictive value were calculated using the METADISC version 1.4 program. Results: Thirty articles elected for quantitative evaluation (meta-analysis), totaling 6,307 nodules with indeterminate cytology, all of which underwent ultrasound, FNAB and surgery with histological confirmation. The US evaluated six morphological ultrasound parameters (Mode B) in the prediction of malignancy, calculating the sensitivity and specificity of each one. The average sensitivity and specificity of the parameters with 95% CI were, respectively: solid composition of 84% and 24%, hypoechogenic of 52% and 55%, strongly hypoechogenic of 21% and 96%, irregular margins 44% and 73%, microcalcifications 33% and 82% and height greater than the width of 26% and 91%. Conclusion: The ultrasound parameters suspected of mode B malignancy assessed individually did not demonstrate sufficient accuracy to rule out malignancy in thyroid nodules in the undetermined category.
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    Alta dose energética de ultrassom terapêutico no tratamento da tendinopatia patelar: ensaio clínico, controlado e randomizado
    (Universidade Federal de São Paulo, 2022-06-09) Jesus, Julio Fernandes de [UNIFESP]; Pinfildi, Carlos Eduardo [UNIFESP]; Cook, Jill; http://lattes.cnpq.br/6370481853776867; http://lattes.cnpq.br/7728969297259998; Universidade Federal de São Paulo (UNIFESP)
    Contextualização: A tendinopatia patelar é uma condição multifatorial e desafiadora, uma vez que causa alterações estruturais no tecido tendíneo, repercussões clínicas debilitantes e em geral, requer uma combinação de abordagens para o seu tratamento. Os exercícios de reabilitação e a alta dose energética de ultrassom terapêutico se mostram promissores para o manejo clínico de tendinopatias. Objetivo: Avaliar o efeito da adição de ultrassom terapêutico com alta dose energética a um programa de exercícios de reabilitação na intensidade da dor e função motora dos membros inferiores de indivíduos com tendinopatia patelar. Métodos: Este foi um ensaio clínico, randomizado, controlado e com cegamento dos pacientes, avaliador e terapeuta. Foram recrutados 66 participantes (homens e mulheres, com idade entre 18 e 40 anos) que apresentavam tendinopatia patelar. O grupo ultrassom terapêutico (UST) recebeu o programa de reabilitação (ultrassom terapêutico: 1MHz, contínuo, 1,2W/cm2, 8’, 4.032J de energia final por sessão e exercícios de reabilitação) 2 vezes por semana, por 8 semanas. O grupo placebo (n=33) recebeu o mesmo tratamento, porém com o ultrassom terapêutico placebo (sem emissão de energia). As mensurações e comparações foram realizadas com os dados iniciais, intermediários (4 semanas) e finais do tratamento (8 semanas), e também com as avaliações de seguimento de 3 e 6 meses. Os desfechos primários foram a intensidade da dor (escala visual analógica, EVA) e o questionário Victorian Institute of Sports Assessment – Patella (VISA-P), os tempos primários foram o inicial (T0) e final do tratamento (T2). Além disso, o questionário International Physical Activity Questionnaire – short form (IPAQ-forma curta), força muscular, cinemática duas dimensões (2D), algometria de pressão, termografia e imagens de ressonância magnética, também foram coletados. Resultados: Embora todos os participantes tenham apresentado melhora dos desfechos avaliados (T0 versus T2) – com exceção da termografia (o grupo UST apresentou temperaturas mais elevadas do que o grupo placebo, p<0,05) – não foram detectadas diferenças entre os grupos (p>0,05). Conclusão: A alta dose energética de ultrassom terapêutico não adicionou efeitos positivos ao programa de exercícios de reabilitação na intensidade da dor e função motora dos membros inferiores de indivíduos com tendinopatia patelar.
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    Amniotic fluid "sludge" is an independent risk factor for preterm delivery
    (Cuba Editora, 2016) Hatanaka, Alan Roberto [UNIFESP]; Mattar, Rosiane [UNIFESP]; Nishimoto Kawanami, Tatiana Emy [UNIFESP]; Franca, Marcelo Santucci [UNIFESP]; Rolo, Liliam Cristine [UNIFESP]; Yamamoto Nomura, Roseli Mieko [UNIFESP]; Araujo Junior, Edward [UNIFESP]; Machado Nardozza, Luciano Marcondes [UNIFESP]; Moron, Antonio Fernandes [UNIFESP]
    Objective: To determine the prevalence and the clinical significance of amniotic fluid sludge (AFS) in asymptomatic patients at low and high risk for spontaneous preterm delivery.Method: A prospective cohort study was conducted on 195 singleton pregnancies at low or high risk for preterm birth (PTB) between the 16th and 26th weeks. Cervical length (CL) <25mm and the presence of AFS were evaluated. The risk for preterm delivery before 28, 32, 35 and 37 weeks were determined according to the presence of AFS, CL<25mm and history of high risk for PTB. Stepwise logistic regression was performed to compare variables.Results: AFS was an independent risk factor for PTB<35 weeks (OR: 3.08, 95% CI: 1.13-8.34, p=0.027) but not for PTB<28, 32 and 37 weeks. CL<25mm was an independent risk factor for PTB<28, 32 and 35 but not for PTB<37 weeks. High risk for PTB was not found as an independent risk factor for PTB.Conclusion: AFS is an independent risk factor for PTB before 35 weeks.
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    Apresentações incomuns do hemangioma hepático: ensaio iconográfico
    (Colégio Brasileiro de Radiologia e Diagnóstico por Imagem, 2006-06-01) D'Ippolito, Giuseppe [UNIFESP]; Appezzato, Luis Fernando; Ribeiro, Alessandra Caivano R.; Abreu Junior, Luiz de; Borri, Maria Lucia [UNIFESP]; Galvão Filho, Mário de Melo; Hartmann, Luiz Guilherme C.; Wolosker, Angela Maria Borri; Universidade Federal de São Paulo (UNIFESP); Hospital São Luiz Serviço de US/TC/RM; Setor de Diagnóstico por Imagem Hospital São Luiz
    In order to evaluate atypical aspects of hepatic hemangiomas at ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI), we have retrospectively analyzed 300 cases of patients diagnosed with hepatic hemangiomas by means of combined imaging studies, clinical follow-up and/or biopsy results. Based on this analysis we have selected those cases with atypical findings at one or more imaging methods or those presenting an unusual evolution such as: hypoechoic nodules at US; giant, heterogeneous hemangiomas; rapidly filling hemangiomas; calcified hemangiomas; pedunculated hemangiomas; hypointense hemangiomas at T2-weighted images; causing perfusion defect; with central scar simulating focal nodular hyperplasia; hemangiomas with adjacent abnormalities such as arterial-portal venous shunt and capsular retraction as well as hemangiomas enlarging over time. The hepatic hemangioma is the most common benign tumor affecting the liver and usually presents typical aspect. However, atypical findings should be known aiming at supporting diagnosis guidance and clinical decisions.
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    Apresentações incomuns do hepatocarcinoma: ensaio iconográfico
    (Colégio Brasileiro de Radiologia e Diagnóstico por Imagem, 2006-04-01) D'Ippolito, Giuseppe [UNIFESP]; Abreu Junior, Luiz de; Borri, Maria Lucia [UNIFESP]; Galvão Filho, Mário de Melo; Hartmann, Luiz Guilherme C.; Wolosker, Angela Maria Borri; Ribeiro, Marcelo [UNIFESP]; Salem, Marcelo Zindel; Misiara, Adriano; Universidade Federal de São Paulo (UNIFESP); Hospital São Luiz - Itaim Serviço de US/TC/RM; Hospital São Luiz Setor de Diagnóstico por Imagem; Universidade de São Paulo (USP)
    In order to evaluate atypical aspects of hepatocellular carcinoma at computed tomography and magnetic resonance imaging, we have retrospectively evaluated 100 patients with diagnosed hepatocellular carcinoma, based on combined imaging studies, laboratory results, biopsy and surgery. We have selected those cases with atypical findings at computed tomography or magnetic resonance imaging, including cystic lesions, bleeding tumors, with calcifications, with spontaneous regression, pedunculated tumors, hypovascular lesions, giant hepatocellular carcinomas, and those with unusual local invasiveness. The hepatocellular carcinoma is the most usual primary malignant lesion of the liver and usually it has a typical aspect and is associated with hepatic cirrhosis. However, in a significant number of cases, some uncommon findings can be responsible for a delayed diagnosis.
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    ARTICULAR ULTRASOUND IN ASYMPTOMATIC VOLUNTEERS: IDENTIFICATION OF THE WORST MEASURES OF SYNOVIAL HYPERTROPHY, SYNOVIAL BLOOD FLOW AND JOINT DAMAGE AMONG SMALL-, MEDIUM- AND LARGE-SIZED JOINTS
    (Elsevier Science Inc, 2017) Machado, Flavia Soares [UNIFESP]; Natour, Jamil [UNIFESP]; Takahashi, Rogerio Diniz [UNIFESP]; Furtado, Rita N. V. [UNIFESP]
    Articular ultrasound of 6500 joint recesses was performed for the purpose of identifying which joint had the highest measurements among small-sized (SSJ), medium-sized (MSJ) and large-sized (LSJ) joints. Quantitative measurements of synovial hypertrophy (QSR) and semiquantitative measurements of synovial hypertrophy (SSH), power Doppler (SPD) and bone erosion (SBE) (score: 0-3) were made. Higher measurements (p < 0.01) of QSR were obtained in the second metatarsophalangeal joint (MTP), talonavicular joint, and hip. The highest SSH scores (2/3) were obtained in the second MTP, talonavicular joint, hip and knee
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    Assessment of ultrasound and doppler parameters in the third trimester of pregnancy as predictors of adverse perinatal outcome in unselected pregnancies
    (Inst Brasileiro Pesquisa & Ensino Fisiologia Exercicio-Ibpefex, 2016) Peixoto, Alberto Borges; Rodrigues da Cunha Caldas, Taciana Mara; Godoy Silva, Tacito Augusto; Silva Gomes Caetano, Mario Sergio; Martins, Wellington P.; Martins Santana, Eduardo Felix [UNIFESP]; Araujo Junior, Edward [UNIFESP]
    Objective: The aim of the study was to investigate ultrasound and Doppler parameters in the third trimester of pregnancy as possible predictors of adverse perinatal outcome in unselected pregnancies. Material and methods: We performed a retrospective cross-sectional study including unselected pregnant women between 27 and 36 + 6 weeks of gestation. The following ultrasound and Doppler parameters were assessed: estimated fetal weight (EFW) [g], EFW percentile, placental maturity grade (Grannum classification), single vertical deepest pocket (SVDP) of amniotic fluid [cm], amniotic fluid index (AFI) [cm], mean uterine artery (UtA) pulsatility index (PI), umbilical artery (UA) PI, middle cerebral artery (MCA) PI, MCA peak systolic velocity (PSV) [cm/s], and cerebroplacental ratio (CPR). Adverse perinatal outcome was defined as Apgar score of < 7 at 1 min, birth weight of < 2500 g at delivery, and gestational age of < 37 weeks at delivery. The unpaired t test was used to compare the groups. Results: AFI (p = 0.01), mean UtA PI (p = 0.04) and mean UA PI (p = 0.03) were significantly different with regard to the Apgar score at 1 min. EFW, EFW percentile, SVDP of amniotic fluid, AFI, mean UtA PI, UA PI, and MCA PI were significantly different (p < 0.001) in terms of birth weight. Placental maturity grade (p = 0.02), SVDP of the amniotic fluid (p < 0.001), AFI (p < 0.001), mean UtA PI (p < 0.001), UA PI (p = 0.001), and MCA PI (p < 0.001) were significantly different as far as gestational age at delivery is concerned. Conclusion: Ultrasound and Doppler parameters may predict adverse perinatal outcomes in unselected pregnancies in the third trimester of pregnancy.
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    Associação entre a obesidade e a lesão do manguito rotador
    (Universidade Federal de São Paulo (UNIFESP), 2020-07-16) Pansiere, Saulo Teixeira [UNIFESP]; Andreoli, Carlos Vicente [UNIFESP]; Universidade Federal de São Paulo
    Rotator cuff tear is a more prevalent lesion among shoulder disorders. As the causes are multifactorial and are related to intrinsic and extrinsic factors, however, the risk factors are not yet clear in the literature, with obesity being one of them. Objective: The present study aimed to understand whether there is a relationship between obesity and rotator cuff injuries. Methods: An observational cross-sectional study was carried out with 235 patients, of both genders, with a BMI > 30mg / m2 and age between 18 and 65 years. We all performed a clinical and ultrasound evaluation of the rotator cuff and divided it into two groups: with and without injury. Results: The injured group had a mean age of 46 years, with a BMI ± 37.2 kg / m2, 65.5% being female, and over 15 years of age exposed to an obese condition. The factors of exposure time (<0.001), age (p <0.001), arterial hypertension (p <0.001) and diabetes (p 0.013) were considered statically prohibited in the group with injury. Conclusion: It was concluded that there is a relationship between obesity and rotator cuff injuries, but being obese does not increase the severity of the injury, but it does decrease the age of the ruptures.
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    Avaliação da concordância entre ressonância magnética de ultra-sonografia na classificação de fibrose periportal em esquitossomóticos, segundo a classificação de Niamey
    (Colégio Brasileiro de Radiologia e Diagnóstico por Imagem, 2007-10-01) Scortegagna Junior, Eduardo [UNIFESP]; Leão, Alberto Ribeiro de Souza [UNIFESP]; Santos, José Eduardo Mourão [UNIFESP]; Sales, Danilo Moulin [UNIFESP]; Shigueoka, David Carlos [UNIFESP]; Aguiar, Luciane Aparecida Kopke de [UNIFESP]; Brant, Paulo Eugênio [UNIFESP]; Colleoni Neto, Ramiro [UNIFESP]; Borges, Durval Rosa [UNIFESP]; D'Ippolito, Giuseppe [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    OBJECTIVE: To evaluate the reproducibility of magnetic resonance imaging and the agreement between ultrasound and magnetic resonance imaging in the classification of periportal fibrosis in patients with schistosomiasis based on Niamey's qualitative criteria. MATERIALS AND METHODS: A prospective, double-blinded study was conducted between February 2005 and June 2006 with 20 patients (10 men and 10 women, with ages ranging between 24 and 60 years, mean age 42.7 years) diagnosed with schistosomiasis mansoni. Both ultrasound and magnetic resonance images were independently evaluated by two experienced observers. Interobserver agreement was evaluated for findings of periportal fibrosis on magnetic resonance images and in a comparison between magnetic resonance and ultrasound images. RESULTS: The analysis of magnetic resonance images showed total interobserver agreement in 14 patients (70%). The comparison between ultrasound and magnetic resonance imaging showed agreement between images in only six cases (30%) by observer 1, and in eight cases (40%) by observer 2. CONCLUSION: Magnetic resonance imaging presents a good reproducibility in the evaluation of periportal fibrosis in later stages of schistosomiasis, however, the correlation between magnetic resonance imaging and ultrasound is poor.
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    Avaliação econômica da obtenção de extrato de bagaço de maracujá: uma comparação entre as técnicas de extração com líquido pressurizado e líquido pressurizado assistida por ultrassom
    (Universidade Federal de São Paulo, 2021-07-15) Ferreira, Wilson Santos [UNIFESP]; Veggi, Priscilla Carvalho [UNIFESP]; Viganó, Juliane; http://lattes.cnpq.br/6020226876173532; http://lattes.cnpq.br/4337428740305589; http://lattes.cnpq.br/8882671734599669
    Natural products and plant extracts have been widely used in recent years and have a growing and relevant importance in the pharmaceutical, food, and cosmetics sectors, due to the bioactive properties of their compounds. The development of extraction technologies and processes are fundamental to the growth of this sector, especially the extraction with supercritical fluids (SFE), with pressurized liquid (PLE), and ultrasound-assisted extraction (US). In the process design step, the use of simulators is one of the most important steps due to the software's ability to predict the behavior of processes, providing information for the project’s economic feasibility analysis and scale-up scenarios. In this context, this work presents the economic feasibility study of two different extraction processes for obtaining a piceatannol-rich extract from yellow passion fruit bagasse, namely, process A (supercritical fluid extraction + pressurized liquid extraction – SFE+PLE) at 65 and 75 ºC and process B (SFE+PLE assisted by ultrasound – SFE+PLE-US) at 65 ºC and 440 W. The SuperPro Designer® software was employed to estimate the manufacturing cost (COM), productivity, and economic return rates, which were calculated for each overall extraction curve (5 to 300 min) and different scales (50, 200, and 500 L). Scale-up increased productivity and reduced COM, improving the economic return rates. Process A proved to be economically viable, while process B was unfeasible at a minimum acceptable rate of return (MARR) of 20%. The lowest COM and the best economic return were obtained with process A at 75 ºC, 500 L scale, and processing time of 90 min. A sensitivity study was carried out and indicated that it is possible to sell the extract at a price below the market price, representing a competitive differential to implement this process. It is noteworthy that up to now, the economic feasibility of PLE-US on a large scale had not yet been performed, so this work represents a starting point for studies of PLE-US hybridization at large scales.
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    Bone quantity and quality in Brazilian female schoolchildren and adolescents
    (Springer, 2009-07-01) Santos, Keila Donassolo; Petroski, Edio Luiz; Ribeiro, Roberto Regis; Guerra-Junior, Gil; Universidade Federal de São Paulo (UNIFESP); Universidade Federal de Santa Catarina (UFSC)
    The aim of the present study was to evaluate quantitative ultrasound parameters of the finger phalanges bones (AD-SoS, amplitude-dependent speed of sound, and BTT, bone transmission time) of schoolchildren, using a DBM Sonic device (IGEA, Carpi, Italy), to obtain normative values for the Brazilian population. the sample consisted of 1,775 healthy schoolchildren, all females, aged 8-17 years. We observed a progressive increase for the variables of weight, height, body mass index (BMI), AD-SoS, and BTT with advancing age. Results for AD-SoS showed increasing and significant variation from 8 to 17 years old (1,938-2,103 m/s, an increase of 8.52%, P < 0.0001), and also for BTT (0.84-1.45 mu s, an increase of 72.6%, P < 0.0001). A gradual increase in the values of AD-SoS and BTT was observed with advances in pubertal stages. There was an interaction between the variables of age, height, and pubertal stages, predicting AD-SoS (R (2) = 0.49) and BTT (R (2) = 0.53). the study showed that AD-SoS and BTT, evaluated by means of bone ultrasonometry of the phalanges in females, increase gradually with age, being more evident during puberty, probably as a reflex of the structural organization of bone growth and development, or changes in the content of the bone tissue.
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    Can ultrasound of plantar plate have normal appearance with a positive drawer test?
    (Elsevier B.V., 2015-03-01) Fernandes, Eloy de Avila [UNIFESP]; Mann, Tania Szejnfeld [UNIFESP]; Puchnick, Andrea [UNIFESP]; Tertulino, Franklin de Freitas [UNIFESP]; Cannato, Camila Testoni [UNIFESP]; Nery, Caio [UNIFESP]; Correa Fernandes, Artur da Rocha [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Objectives: the aims of this study were (1) to evaluate the reliability of ultrasound (US) examination in the identification and measurement of the metatarsophalangeal plantar plate (MTP-PP) in asymptomatic subjects and (2) to establish the correlation of US findings with those of physical examination and magnetic resonance imaging (MRI), once it is an important tool in the evaluation of the instability syndrome of the second and third rays.Materials and Methods: US examinations of the second and third MTP-PPs were performed in eight asymptomatic volunteers, totaling 32 MTP joints, by three examiners with different levels of experience in musculoskeletal US. Plantar plate dimensions, integrity and echogenicity, the presence of ruptures, and confidence level in terms of structure identification were determined using conventional US. Vascular flow was assessed using power Doppler. US data were correlated with data from physical examination and MRI.Results: MTP-PPs were ultrasonographically identified in 100% of cases, always showing homogeneous hyperechoic features and no detectable vascular flow on power Doppler, with 100% certainty in identification for all examiners. There was excellent US inter-observer agreement for longitudinal measures of second and third toe MTP-PPs and for transverse measures of the second toe MTP-PP. the MTP drawer test was positive for grade 1 MTP instability in 34.4% of joints with normal US results. Transverse MTP-PP measures were significantly higher in individuals with positive MTP drawer test. US measures and characteristics of MPT-PPs were positively correlated with those of MRI.Conclusions: US is efficient in identifying and measuring MPT-PPs and may complement physical examination. A grade 1 positive MTP drawer test may be found in asymptomatic individuals with normal MPT-PPs, as assessed by imaging. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
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    Central de ultrassom: proposta de rastreamento de malformações cardíacas fetais
    (Universidade Federal de São Paulo (UNIFESP), 2016-07-12) Barros, Lidiane Pereira dos Reis [UNIFESP]; Carvalho, Antonio Carlos de Camargo [UNIFESP]; http://lattes.cnpq.br/6569055379421505; http://lattes.cnpq.br/2154399933069784; Universidade Federal de São Paulo (UNIFESP)
    Objective: To elaborate a proposal to assist in the identification of fetal cardiac malformations by creating an model Ultrasound Central to be designed in conjunction with a medical training methodology and a computational tool that allows the transmission of fetal heart images through Internet, acquired during obstetric exam or morphological ultrasound performed in a healthcare facility to one or more centers, formed by specialists in fetal cardiology, to assist on the diagnosis. Methods: For the development, the work was organized in three blocks: Research and Development, Methodology and Technological Solution. In block one: Research and Development, the project was conceived and the requirements determined. In block two: Methodology, establishment of a methodology to train obstetricians in the identification of fetal cardiac malformations, through medical training and in block three: Technological Solution, implementation of a system for the operation of the Ultrasound Central and its requirements. Results: Block one results were achieved through the possibility of using various types of ultrasound equipment in the solution, including analogue ones, and allowing the compression of the exams without losing the quality needed for report elaboration. In block two, a training program was developed to train physicians in the recognition of fetal heart malformations and system usage, and in block three, the creation of a viable product to fulfils the flow of the processes designed for the solution, such as, sending of morphological obstetric ultrasound examinations on the Internet, to a central with specialists in ecocardiofetal issue a second opinion of the report or guidance for the accomplishment of the examination, tools for image analysis to evaluate the exam, among others. Conclusion: The three objectives proposed in the thesis were attended, in the spheres of elaboration of the Ultrasound Central model, creation of the methodology to help the identification of fetal cardiac malformations and implementation of the computational tool.
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    Cistos primários do epitélio pigmentar da íris e corpo ciliar: aspectos de biomicroscopia ultra-sônica
    (Conselho Brasileiro de Oftalmologia, 2000-10-01) Ayres, Bernadete; Allemann, Norma [UNIFESP]; Nakanami, Celia [UNIFESP]; Adan, Consuelo B. D. [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Purpose: To describe the ultrasound biomicroscopic characteristics, incidence, distribution and location of primary cysts of the iris and ciliary body pigment epithelium, and to differentiate them from solid lesions. Methods: A retrospective study was performed through a review of charts of 73 patients, 82 eyes, with echographic diagnosis of primary cysts of the iris and ciliary body pigment epithelium during a 36-month period (January/97 through December/99). All examinations were performed using an ultrasound biomicroscope applying standard immersion techniques. Results: Ultrasound biomicroscopy revealed typical findings of the primary cysts of the pigment epithelium such as thin and regular walls with no internal content. Incidence was higher in individuals included in the interval of 20 to 29 years of age (28.8%). Forty-eight patients (65.7%) were female. The cysts were found most frequently in the inferior and temporal sectors. Conclusions: Ultrasound biomicroscopy was a useful tool for evaluating cystic lesions of the iris and ciliary body, also valuable in differentiating these lesions from anterior segment tumors and evaluating potential complications. The knowledge of the echographic criteria and epidemiological characteristic can assist in the diagnosis of these lesions.
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    Comparação dos efeitos do laser de baixa potência e do ultrassom de baixa intensidade associado ao Biosilicato® no processo de reparo ósseo em tíbias de ratos
    (Sociedade Brasileira de Ortopedia e Traumatologia, 2012-02-01) Oliveira, Poliani de; Fernandes, Kelly Rossetti [UNIFESP]; Sperandio, Evandro Fornias [UNIFESP]; Pastor, Fabio Alexandre Casarin; Nonaka, Keico Okino; Parizotto, Nivaldo Antonio; Renno, Ana Claudia Muniz [UNIFESP]; Universidade Federal de São Carlos; Universidade Federal de São Paulo (UNIFESP)
    OBJECTIVE: Verify the effects of the association between Biosilicate® and ultrasound and, Biosilicate® and laser in bone consolidation process of rats, through the biomechanical and histological analysis. METHODS: Forthy male rats were used. The animals were randomized into four groups (n=10): control group fracture no treated (CGF); group treated with Biosilicate® (BG); group treated with Biosilicate® and laser (BLG); group treated with Biosilicate® and ultrasound (BUG). RESULTS: The biomechanical analysis showed no significant difference among any groups after 14 days post-surgery. In the morphometric analysis, the control group showed moderate presence of new formed bone tissue inside the defects areas and the Biosilicate® group showed similar results. Despite those facts, the biomaterial osteogenic potential was demonstrated by the great amount of cells and bone tissue around the particles. Curiously, the Biosilicate® plus laser or ultrasound groups showed lower amounts of bone tissue deposition when compared with control fracture and Biosilicate® groups. CONCLUSION: The data from this study can conclude that Biosilicate® was able to accelerate and optimized the bone consolidation, through the modulation of the inflammatory process and the stimulation of new bone formation. However, when resources were associated, there are no positive results.
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    Comparação dos efeitos do laser de baixa potência e do ultrassom de baixa intensidade no processo de reparo ósseo em tíbia de rato
    (Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia, 2011-06-01) Oliveira, Poliani de; Sperandio, Evandro Fornias; Fernandes, Kelly Rossetti [UNIFESP]; Pastor, Fabio Alexandre Casarin; Nonaka, Keico Okino; Renno, Ana Claudia Muniz [UNIFESP]; Universidade Federal de São Carlos; UFSCar Departamento de Ciências Fisiológicas; Universidade Federal de São Paulo (UNIFESP)
    BACKGROUND: Electrophysical agents such as Ultrasound (US) and low-level laser therapy (LLLT) have been increasingly used in physical therapy practice. Studies suggest that these devices are able to stimulate osteoblast proliferation and osteogenesis at the fracture site, resulting in a greater deposition of bone mass and speeding up the consolidation process. OBJECTIVE: The aim of this study was to analyze the effects of US and LLLT on the bone healing process, through biomechanical and histological analysis of the bone callus. METHODS: A total of 30 rats were randomly allocated into three groups: control group fracture without treatment (GC); fracture group treated with pulsed US, burst 1.5 MHz, 200us, 1KHz, 30 mW/cm² (GUS) and fracture group treated with laser 830nm, 100mW, 120J/cm² (GL). Bone defects were performed with a circular drill of 2mm in diameter in the animal's tibias. The treatments were carried out after surgery consisting of 7 applications every 48 hours. After 14 days the animals were sacrificed and the tibias were removed to perform the analysis, being the right tibia designated for biomechanical analysis, while the left tibia for histological analysis. RESULTS: The biomechanical analysis showed no statistically significant difference between biomechanical properties of the CG, CL and GUS. In morphometric analysis, both GUS and GL showed a significantly higher woven bone tissue area compared to the control group. However, when the two treatment modalities were compared, there were no statistical differences between them. CONCLUSION: Both devices used in this study were able to accelerate the bone healing process in rats.
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    Comparative study of the effects of low-intensity pulsed ultra-sound and low level laser therapy on injured muscle repair
    (Spie-int Soc Optical Engineering, 2011-01-01) Renno, Ana Claudia Muniz [UNIFESP]; Toma, Renata Luri [UNIFESP]; Feitosa, Suellen Maurin [UNIFESP]; Fernandes, Kelly Rossetti [UNIFESP]; Oliveira, Poliani de [UNIFESP]; Parizotto, Nivaldo Antonio [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP]; Hamblin, Michael R.; Waynant, R. W.; Anders, J.; Universidade Federal de São Paulo (UNIFESP)
    Muscle tissue is one of the most frequently affected by injury, whether during sports activities, or work activities. in this context, biochemical and biophysical resources have been studied to minimize the time of muscle regeneration. Among these, low intensity pulsed ultrasound (US) and low level laser therapy (LLLT) may be highlighted. Despite a series of evidences about the positive effects of these resources in the process of tissue regeneration, the cellular and morphological changes triggered by LLLT and U. S. are still largely unknown. Thus, the aim of this study was to investigate the effects of US and LLLT on muscle repair after cryolesion by means of histopathological analysis and immunohistochemistry for COX-2. A total of thirty five male Wistar rats were randomly distributed into 4 groups: intact control group; injured control group: muscle injured animals without any treatment; laser treated group: muscle injured animals treated with 830 nm laser and ultra-sound treated group: muscle injured animals treated with US. the treatments started 24 hours post-surgery and were performed during 6 sessions. the animals exposed to lasertherapy pointed out minor degenerative changes of muscle tissue. in the same way, exposure to ultrasound was able to reduce tissue injuries induced by cryolesion, but less intense than laser therapy. Strong COX-2 positive cells were found in rats submitted to cryolesion only, whereas COX-2 immunoexpression was lower in laser treated or ultrasound treated groups. in summary, this study reveals that both lasertherapy and ultrasound have positive effects on muscle repair in rats.
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    Consensus Paper: Radiological Biomarkers of Cerebellar Diseases
    (Springer, 2015-04-01) Baldarcara, Leonardo [UNIFESP]; Currie, Stuart; Hadjivassiliou, M.; Hoggard, Nigel; Jack, Allison; Jackowski, Andrea P. [UNIFESP]; Mascalchi, Mario; Parazzini, Cecilia; Reetz, Kathrin; Righini, Andrea; Schulz, Joerg B.; Vella, Alessandra; Webb, Sara Jane; Habas, Christophe; Fed Univ Tocantins; Universidade Federal de São Paulo (UNIFESP); Univ Sheffield; Royal Hallamshire Hosp; Yale Univ; Univ Florence; Meyer Children & Careggi Hosp Florence; Childrens Hosp Buzzi; RWTH Aachen Univ Hosp; Forschungszentrum Julich; Julich Aachen Res Alliance JARA; Univ Hosp Siena; Univ Washington; CHNO Quinze Vingts
    Hereditary and sporadic cerebellar ataxias represent a vast and still growing group of diseases whose diagnosis and differentiation cannot only rely on clinical evaluation. Brain imaging including magnetic resonance (MR) and nuclear medicine techniques allows for characterization of structural and functional abnormalities underlying symptomatic ataxias. These methods thus constitute a potential source of radiological biomarkers, which could be used to identify these diseases and differentiate subgroups of them, and to assess their severity and their evolution. Such biomarkers mainly comprise qualitative and quantitative data obtained from MR including proton spectroscopy, diffusion imaging, tractography, voxel-based morphometry, functional imaging during task execution or in a resting state, and from SPETC and PET with several radiotracers. in the current article, we aim to illustrate briefly some applications of these neuroimaging tools to evaluation of cerebellar disorders such as inherited cerebellar ataxia, fetal developmental malformations, and immune-mediated cerebellar diseases and of neurodegenerative or early-developing diseases, such as dementia and autism in which cerebellar involvement is an emerging feature. Although these radiological biomarkers appear promising and helpful to better understand ataxia-related anatomical and physiological impairments, to date, very few of them have turned out to be specific for a given ataxia with atrophy of the cerebellar system being the main and the most usual alteration being observed. Consequently, much remains to be done to establish sensitivity, specificity, and reproducibility of available MR and nuclear medicine features as diagnostic, progression and surrogate biomarkers in clinical routine.
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    Conservative interventions for treating middle third clavicle fractures in adolescents and adults
    (Inst Israelita Ensino & Pesquisa Albert Einstein, 2016) Lenza, Mario; Faloppa, Flavio [UNIFESP]
    Background Clavicle (collarbone) fractures account for around 4% of all fractures. Most (76%) clavicle fractures involve the middle-third section of the clavicle. Treatment of these fractures is usually non-surgical (conservative). Commonly used treatments are arm slings, strapping and figure-of-eight bandages. This is an update of a Cochrane review first published in 2009 and updated in 2014. Objectives To evaluate the effects (benefits and harms) of different methods for conservative (non-operative) treatment for acute (treated soon after injury) middle third clavicle fractures in adolescents and adults. Search methods We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register, the Cochrane Central Register of Controlled Trials, MEDLINE (from 1966), Embase (from 1980), LILACS (from 1982), trial registers, orthopaedic proceedings and reference lists of articles. We applied no language or publication restrictions. The date of the last search was 5 January 2016. Selection criteria Randomised and quasi-randomised controlled trials testing conservative interventions for treating adolescents and adults with acute middle third clavicle fractures. The primary outcomes were shoulder function or disability, pain and treatment failure. Data collection and analysis For this update, two review authors selected eligible trials, independently assessed risk of bias and cross-checked data extraction. We calculated risk ratios and 95% confidence intervals for dichotomous variables, and mean differences and 95% confidence intervals for continuous variables. There was very limited pooling of data. Main results We included four trials in this review with 416 participants, who were aged 14 years or above. One new trial was included in this update. Very low quality evidence was available from three trials (296 participants) that compared the figure-of-eight bandage with an arm sling for treating acute middle third clavicle fractures. The three trials were underpowered and compromised by poor methodology. Shoulder function was assessed in different ways in the three trials (data for 51, 61 and 152 participants)
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    Contribuição da mamografia e da ultra-sonografia na avaliação da mama reconstruída com retalho miocutâneo
    (Colégio Brasileiro de Radiologia e Diagnóstico por Imagem, 2006-02-01) Louveira, Maria Helena; Kemp, Claudio [UNIFESP]; Vilar, Vanessa Sales [UNIFESP]; Elias, Simone [UNIFESP]; Spadoni, Cristiane Grein Basso; Gracino, Alencar; Szejnfeld, Jacob [UNIFESP]; Colégio Brasileiro de Radiologia e Diagnóstico por Imagem; Universidade Federal de São Paulo (UNIFESP); CBR
    Breast reconstruction using myocutaneous flaps has been widely used in patients undergoing modified radical mastectomy for the treatment of breast cancer with significant improvement in esthetical results, which also helps to improve self-esteem of the patients as it minimizes the feeling of mutilation, without changing disease prognosis. Previously, it was believed that there was no risk of recurrence in the reconstructed breast due to the complete removal of breast tissue. However, histological studies have shown that a small amount of glandular tissue may remain after mastectomy, with a high potential for malignancy. Clinical follow-up of mastectomy patients is recommended as most recurring lesions occur at the flap margins and can be detected by palpation. In addition, the inclusion of mammographic and ultrasound monitoring has been proposed for the follow-up of patients as these methods may contribute to the diagnosis of recurrent lesions before they become palpable.