Navegando por Palavras-chave "Tissue Survival"

Agora exibindo 1 - 2 de 2
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Effect of high frequency transcutaneous electrical nerve stimulation on viability of random skin flap in rats
    (Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2006-06-01) Liebano, Richard Eloin [UNIFESP]; Abla, Luiz Eduardo Felipe [UNIFESP]; Ferreira, Lydia Masako [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    PURPOSE: To determine the effect of high frequency Transcutaneous Electrical Nerve Stimulation (TENS) on viability of random skin flap in rats. METHODS: The sample of this study was 75 Wistar rats. The skin flap measured 10 x 4 cm and a plastic barrier was interposed between the flap and donor site. After the operative procedure, animals of all groups were maintained anesthetized one more hour with electrodes positioned in the base of the flap and submitted to treatment according of their respective group. This procedure was repeated on the two subsequent days. G1: sham stimulation (control), G2: TENS (f = 80 Hz and I = 5 mA), G3: TENS (f = 80 Hz and I = 10 mA), G4: TENS (f = 80 Hz and I = 15 mA), G5: TENS (f = 80 Hz and I = 20 mA). RESULTS: The average percentage of necrotic area was 43,11, 34,65, 49,44, 23,52, 45,10 in groups 1, 2, 3, 4 and 5 respectively. CONCLUSION: The amplitude of 15 mA presented a lower necrotic area than control group and Transcutaneous Electrical Nerve Stimulation was efficient in increasing the random skin flap viability.
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Experimental model of cranially pedicled TRAM flap in rats
    (Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2004-12-01) Garcia, Elvio Bueno [UNIFESP]; Ferreira, Lydia Masako [UNIFESP]; Sabino Neto, Miguel [UNIFESP]; Sallum, Natasha [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Medicine School of Bahia
    In a simple, reproducible, and non-expensive experimental model the transverse rectus abdominis muscle (TRAM) flap has been described in male, adult Wistar rats (Rattus norvegicus albinus, Rodentia, Mammalia), weighing approximately 300g, at the central biotery of the Federal University at São Paulo, Paulista Medical School (UNIFESP - EPM). This article describes the use of a cranially based pedicled rectus abdominis muscle flap sling, unilaterally to the right, with the purpose to better understand the pathophysiology of and the research on new treatments to prevent partial or total flap necrosis. This experimental model sponsors quite a number of studies to be conducted to assess the effects of different drugs of physical methods on the feasibility of standard, cranial monopedicled TRAM.As a standard model, it also harbors the comparison among results from different studies.