Navegando por Palavras-chave "TENS"

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    Effects of transcutaneous electrical nerve stimulation on fetal and placental development in an experimental model of placental insufficiency
    (Taylor & Francis Ltd, 2016) Guimaraes, Camila S. O.; Gomes, Bruno B. F.; Oliveira, Rafael A.; Yamamoto, Leandro R.; Rocha, Laura P.; Gloria, Maria A. [UNIFESP]; Machado, Juliana R.; Camara, Niels O. S. [UNIFESP]; Reis, Marlene A.; Correa, Rosana R. M.
    Objective: To elucidate the effects of transcutaneous electrical nerve stimulation (TENS) in pregnancies with placental insufficiency.Methods: Pregnant rats were subjected to uterine artery ligation and to TENS according to the following groups: ligated stimulated (LS); ligated non-stimulated (LN), control stimulated (CS); and control non-stimulated (CN). Fetal external measurements, such as crown-rump length (CRL), fronto-occipital distance (FOD), thoracic ventral-dorsal (TVDD) and abdominal ventral-dorsal (AVDD) distances were analyzed together with the area occupied by fetal internal organs. Glucose transporter 1 (GLUT-1) expression was evaluated by immunohistochemistry in fetal organs. Thickness of junctional, labyrinth and intermediate placental zones was analyzed by morphometric evaluation in HE-stained slides, and placental hypoxia-inducible factor 1 alfa expression was measured by real-time polymerase chain reaction.Results: In LN and CS groups compared to the CN group, CRL was reduced (27.51/28.95 versus 30.16mm), as well as FOD (6.63/6.63 versus 7.36mm), AVDD (7.38/8.00 versus 8.61mm) and TVDD (6.46/6.87 versus 7.23mm). Brain GLUT-1 expression was higher in LS (1.3%) and CS (1.8%). The area occupied by placental vessels in the labyrinth zone (29.673.51 versus 20.83 +/- 7.63) and intermediate zone (26.46 +/- 10.21 versus 10.86 +/- 8.94) was larger in the LS group than in the LN group.Conclusions: Our results suggest a negative effect of TENS on placental development, thus compromising the maintenance of adequate blood flow to the fetus.
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    Effects of transcutaneous electrical nerve stimulation on fetal and placental development in an experimental model of placental insufficiency
    (Taylor & Francis Ltd, 2016) Guimaraes, Camila S. O.; Gomes, Bruno B. F.; Oliveira, Rafael A.; Yamamoto, Leandro R.; Rocha, Laura P.; Gloria, Maria A. [UNIFESP]; Machado, Juliana R.; Camara, Niels O. S. [UNIFESP]; Reis, Marlene A.; Correa, Rosana R. M.
    Objective: To elucidate the effects of transcutaneous electrical nerve stimulation (TENS) in pregnancies with placental insufficiency.Methods: Pregnant rats were subjected to uterine artery ligation and to TENS according to the following groups: ligated stimulated (LS); ligated non-stimulated (LN), control stimulated (CS); and control non-stimulated (CN). Fetal external measurements, such as crown-rump length (CRL), fronto-occipital distance (FOD), thoracic ventral-dorsal (TVDD) and abdominal ventral-dorsal (AVDD) distances were analyzed together with the area occupied by fetal internal organs. Glucose transporter 1 (GLUT-1) expression was evaluated by immunohistochemistry in fetal organs. Thickness of junctional, labyrinth and intermediate placental zones was analyzed by morphometric evaluation in HE-stained slides, and placental hypoxia-inducible factor 1 alfa expression was measured by real-time polymerase chain reaction.Results: In LN and CS groups compared to the CN group, CRL was reduced (27.51/28.95 versus 30.16mm), as well as FOD (6.63/6.63 versus 7.36mm), AVDD (7.38/8.00 versus 8.61mm) and TVDD (6.46/6.87 versus 7.23mm). Brain GLUT-1 expression was higher in LS (1.3%) and CS (1.8%). The area occupied by placental vessels in the labyrinth zone (29.673.51 versus 20.83 +/- 7.63) and intermediate zone (26.46 +/- 10.21 versus 10.86 +/- 8.94) was larger in the LS group than in the LN group.Conclusions: Our results suggest a negative effect of TENS on placental development, thus compromising the maintenance of adequate blood flow to the fetus.
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    Transcutaneous Electrical Nerve Stimulation for Pain Relief After Liposuction: A Randomized Controlled Trial
    (Springer, 2015-04-01) Silva, Milla Pompilio da [UNIFESP]; Liebano, Richard Eloin; Rodrigues, Victor Ales [UNIFESP]; Felipe Abla, Luiz Eduardo [UNIFESP]; Ferreira, Lydia Masako [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Univ City São Paulo UNICID
    Liposuction is a common cosmetic surgical procedure, which requires analgesia for postoperative pain. Transcutaneous electrical nerve stimulation (TENS) has been used for postoperative pain relief; however, there is no evidence of its effectiveness in liposuction patients and this is the focus of this paper.A prospective, randomized, double-blind, controlled trial was conducted with 42 adult patients who underwent liposuction. Patients were randomly allocated to either the TENS group (active TENS) or control group (sham TENS). All patients received morphine (0.1 mg/kg) and dipyrone 1 g immediately after surgery; TENS was delivered 2 h later. the primary outcome was pain intensity. Secondary outcomes were analgesic requirement, number and types of adverse effects of TENS, quality of pain, treatment success, and patient satisfaction. Postoperative pain was measured using a visual analog scale (VAS) and the Brazilian version of the McGill Pain Questionnaire (Br-MPQ).Patients in the TENS group reported significantly lower pain intensity (P < 0.001, effect size = 0.92) compared with those in the control group. TENS significantly decreased the consumption of analgesics in the postoperative period (P < 0.001). No withdrawals or adverse effects were observed in the TENS group, but 33.3 % of patients in the control group reported drowsiness and nausea. About 95 and 38 % of patients in the TENS and control groups, respectively, were satisfied with the analgesic treatment.The results indicate that TENS is effective as an adjunct to analgesics for pain relief after liposuction.This journal requires that authors assign a level of evidence to each article. for a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
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    Transcutaneous electrical nerve stimulation in viability of a random skin flap in nicotine-treated rats
    (Lippincott Williams & Wilkins, 2006-12-01) Abrantes Russo, Claudia Regina; Leite, Mauro Teixeira; Gomes, Heitor Carvalho; Ferreira, Lydia Masako; Universidade Federal de São Paulo (UNIFESP)
    Background: Skin flaps are extensively used in plastic surgery, the main postoperative problems being ischemia and necrosis. Nicotine has acute vasoconstrictive properties, diminishing blood flow and increasing the risk of flap necrosis. Transcutaneous electrical nerve stimulation (TENS) was effective in reducing necrosis in random skin flaps in rats. Therefore, the authors decided to test the efficacy of TENS to reduce necrosis in the presence of nicotine.Methods: Sixteen adult male Wistar-Escola Paulista de Medicina (EPM) rats were distributed, at random, in 2 groups of 8 animals. the nicotine group (NG) received this drug subcutaneously (1.2 mg/kg/d), for 1 week before flap elevation. the nicotine plus TENS group (NTG) followed the same routine. Immediately after the operative procedure and on the next 2 postoperative days, the treatment group (NTG) was submitted to TENS during an hour under anesthesia. NG animals were sham exposed. After 7 days, the percentages of necrosis were determined.Results: the NG had a mean value of 45% and the NTG, 21% of necrosis, a difference statistically significant (P < 0.001).Conclusion: TENS was effective in the reduction of necrosis in this flap model.