Navegando por Palavras-chave "Serum albumin"

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    Influência do trauma cirúrgico no comportamento dos níveis séricos de albumina após cirurgia da coluna vertebral
    (Sociedade Brasileira de Coluna, 2010-12-01) Luciano, Rafael Paiva [UNIFESP]; Leite, Marcio Squassoni [UNIFESP]; Martins, Délio Eulálio [UNIFESP]; Wajchenberg, Marcelo [UNIFESP]; Puertas, Eduardo Barros [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    OBJECTIVE: to evaluate the variation of serum albumin concentration in surgery of the spine and its relation to clinical effects in the postoperative. METHODS: prospective observational study on the values of serum albumin of 55 patients undergoing spine surgery.Blood samples were collected one day before and 24 hours after the procedure. The paired t test was performed to evaluate the change parameters albumin, hemoglobin and hematocrit. The presence of association between the degree of variation in levels of albumin (<1 g/dL or >1 g/dL) and the variables of interest: complications, transfusions, procedures performed, patients' age and sex and diagnosis were assessed by χ2 test or the χ2 likelihood ratio when appropriate. RESULTS: the average reduction of this protein was of 0.58 g/dL, ranging from 0 to 1.8 g/dL. Of the patients, 78.2% showed albumin values in the postoperative period below the normal range. Only two patients presented with complications during the 30 days of follow-up. The group with the correction of deformities showed 100% of patients with variation of >1 g/dL. CONCLUSION: there was an influence of the surgical trauma in reducing serum albumin, on average, 0.58 g/dL in surgery of the spine. It was not possible to associate this decrease to complications in the postoperative period after 30 days of follow-up of these patients.
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    Use of albumin as a risk factor for hospital mortality among burn patients in Brazil: non-concurrent cohort study
    (Associação Paulista de Medicina - APM, 2010-01-01) Caleman, Gilson [UNIFESP]; Morais, José Fausto de; Puga, Maria Eduarda dos Santos [UNIFESP]; Riera, Rachel [UNIFESP]; Atallah, Álvaro Nagib [UNIFESP]; Faculdade de Medicina de Marília; Universidade Federal de Uberlândia; Brazilian Cochrane Center; Universidade Federal de São Paulo (UNIFESP)
    CONTEXT AND OBJECTIVE: Among burn patients, it is common to use colloidal substances under the justification that it is necessary to correct the oncotic pressure of the plasma, thereby reducing the edema in the burnt area and the hypotension. The aim here was to assess the risk of hospital mortality, comparing the use of albumin and crystalloid solutions for these patients. DESIGN AND SETTING: Non-concurrent historical cohort study at Faculdade de Medicina de Marília; within the Postgraduate program on Internal and Therapeutic Medicine, Universidade Federal de São Paulo (UNIFESP); and at the Brazilian Cochrane Center. METHODS: Burn patients hospitalized between 2000 and 2001, with registration in the Hospital Information System, who received albumin, were compared with those who received other types of volume replacement. The primary outcome was the hospital mortality rate. The data were collected from files within the Datasus software. RESULTS: 39,684 patients were included: 24,116 patients with moderate burns and 15,566 patients with major burns. Among the men treated with albumin, the odds ratio for the risk of death was 20.58 (95% confidence interval, CI: 11.28-37.54) for moderate burns and 6.24 (CI 5.22-7.45) for major burns. Among the women, this risk was 40.97 for moderate burns (CI 21.71-77.30) and 7.35 for major burns (CI 5.99-9.01). The strength of the association between the use of albumin and the risk of death was maintained for the other characteristics studied, with statistical significance. CONCLUSION: The use of albumin among patients with moderate and major burns was associated with considerably increased mortality.