Navegando por Palavras-chave "SF-36"

Agora exibindo 1 - 16 de 16
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Autologous stem cell transplantation improves quality of life in economically challenged, Brazilian multiple myeloma patients
    (Faculdade de Medicina / USP, 2011-01-01) Etto, Leina Y [UNIFESP]; Morel, Vânia Maris [UNIFESP]; Silva, Vanderleia C [UNIFESP]; Hungria, Vania Tietsche de Moraes; Ciconelli, Rozana Mesquita [UNIFESP]; Almeida, Manuella S. S [UNIFESP]; Oliveira, José Salvador Rodrigues de [UNIFESP]; Barros, José Carlos; Durie, Brian G; Colleoni, Gisele Wally Braga [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Santa Casa de Misericórdia de São Paulo Faculdade de Ciências Médicas; Cedars-Sinai Outpatient Cancer Center
    OBJECTIVES: 1) To characterize the impact of multiple myeloma on the quality of life of patients treated in two public institutions in São Paulo State, Brazil, using a generic Short Form 36 Health Survey and a questionnaire specific for oncologic patients (QLQ-C30) upon diagnosis, after the clinical treatment, and at day +100 after autologous stem cell transplantation; 2) to evaluate whether autologous stem cell transplantation can improve the quality of life of our economically challenged population aside from providing a clinical benefit and disease control. METHODS: We evaluated 49 patients with multiple myeloma (a total of 70 interviews) using the two questionnaires. The scores upon diagnosis, post-treatment/pre-autologous stem cell transplantation, and at D+100 were compared using ANOVA (a comparison of the three groups), post hoc tests (two-by-two comparisons of the three groups), and paired t-tests (the same case at two different times). RESULTS: Of the included patients, 87.8% had a family budget under US $600 (economic class C, D, or E) per month. The generic Short Form 36 Health Survey questionnaire demonstrated that physical function, role-physical, and bodily pain indices were statistically different across all three groups, favoring the D+100 autologous stem cell transplantation group (ANOVA). The questionnaire specific for oncologic patients, the QLQ-C30 questionnaire, confirmed what had been demonstrated by the Short Form 36 Health Survey with respect to physical function and bodily pain, with improvements in role functioning, fatigue, and lack of appetite and constipation, favoring the D+100 autologous stem cell transplant group (ANOVA). The post hoc tests and paired t-tests confirmed a better outcome after autologous stem cell transplantation CONCLUSION: The questionnaire specific for cancer patients seems to be more informative than the generic Short Form 36 Health Survey questionnaire and reflects the real benefit of autologous stem cell transplantation in the quality of life of multiple myeloma patients in two public Brazilian institutions that provide assistance for economically challenged patients.
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Comparação da qualidade de vida e sobrecarga dos cuidadores de pacientes com epilepsia por esclerose mesial temporal e epilepsia mioclônica juvenil
    (Liga Brasileira de Epilepsia (LBE), 2005-01-01) Westphal, Ana Carolina [UNIFESP]; Alonso, Neide Barreira [UNIFESP]; Silva, Tatiana Indelicato Da [UNIFESP]; Azevedo, Auro Mauro [UNIFESP]; Caboclo, Luís Otávio Sales Ferreira [UNIFESP]; Garzon, Eliana [UNIFESP]; Sakamoto, Américo Ceiki [UNIFESP]; Yacubian, Elza Márcia Targas [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    INTRODUCTION: The relationship pattern between patient and caregiver can influence in quality of life (QOL) and growth of both. OBJECTIVE: To compare QOL and burden over the caregivers of patients with refractory temporal lobe epilepsy (TLE) due to mesial temporal sclerosis and juvenile myoclonic epilepsy (JME). CASUISTIC AND METHODS: 20 caregivers of patients with TLE and 20 of patients with JME were evaluated. The QOL Inventory SF-36 and the Caregiver Burden Questionnaire Burden Interview - Zarit - were applied. RESULTS: When QOL of both groups was compared, no relation statistically significant was observed between caregivers for JME and TLE, as well as burden on them. There was a correlation for burden on the caregivers of JME patients and the following domains of SF-36: General Health Status (p = 0.011), Emotional Limitation Aspects (p = 0.037) e Mental Health (p = 0.002). CONCLUSION: The burden on the caregivers of both groups was similar and did not interfere in QOL in most of SF-36 domains. However, caregivers of patients with JME suffered greater impact in domains related to physical and emotional health. In spite of more adequate seizure control in JME patients this burden might be heavier due to greater exposure to daily activities.
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Efeitos da abordagem interdisciplinar na qualidade de vida e em parâmetros laboratoriais de pacientes com doença renal crônica
    (Univ Sao Paulo, Inst Psiquiatria, 2008-01-01) Santos, Fabiane Rossi dos; Filgueiras, Maria Stella Tavares; Chaoubah, Alfredo; Bastos, Marcus Gomes [UNIFESP]; Paula, Rogerio Baumgratz de [UNIFESP]; Fundacao IMEPEN; Pontificia Univ Catolica Rio de Janeiro; Univ Fed Juiz Fora; Universidade Federal de São Paulo (UNIFESP); UFJF
    Background: Multidisciplinary team-based care (MDC) of patients with chronic kidney disease (CKD) before the beginning of the renal replacement therapy may improve their quality of life. Objectives: This study aimed to assess the impact of MDC on the quality of life patients with CKD not yet on dialysis. Methods: Seventy five patients treated by MDC (n = 50) or by standard medical care (n = 25) were evaluated at the beginning and after one year of follow-up. Quality of life was assessed by the Medical Outcomes Study Questionnaire 36 - Item Short Form Health Survey (SF-36). Clinical and laboratory parameters were obtained from the patients' charts. Results: After 1-year of follow-up, the patients in MDC improved the following dimensions of the SF-36: functional capacity, physical features, general health, vitality and mood. On the other hand, the control group did not improve any dimension in quality of life. At the end of the study, the patients followed by the MDC lost body weight and showed statistically significant increases in hemoglobin and calcium plasma levels, when compared to control group. Discussion: Our results showed that, compared to the standard medical care, the MDC contributed to achieve a better quality of life and clinical control in patients with CKD not yet on dialysis.
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    The Experience of Caregiving Inventory for first-episode psychosis caregivers: Validation of the Brazilian version
    (Elsevier B.V., 2012-07-01) Ferreira de Araujo Jorge, Rita de Cassia [UNIFESP]; Chaves, Ana Cristina [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Family members of first-episode psychosis (FEP) patients are regarded as key components of the patient's evaluation, recovery and treatment. This paper aimed to investigate 75 FEP caregivers' appraisal, psychological morbidity and quality of life in the initial phase of treatment in a specialized FEP outpatient program in São Paulo, Brazil, and evaluate the validation of the Brazilian version of the Experience of Caregiving Inventory (ECI). Caregivers were also scored through Self Report Questionnaire-20 and Short Form-36. It was found that 29% of them might be a case for minor psychiatric disorder, that the worst domains of quality of life concerned emotional aspects, vitality and bodily pain, and that they were particularly affected by patients' negative symptoms, dependency and difficult behaviors. Additionally, internal consistency of ECI was very satisfactory (Cronbach's alpha = 0.95) with subscales ranging from 0.57 (stigma) to 0.94 (total negative score). the Brazilian version of the ECI is not only a facile, reliable and valid instrument to describe the experience of caring for a relative with serious mental illness. It offers mental health professionals an opportunity to access caregivers' global experience and their evaluation of a severe mental disease, as well as to predict their psychological suffering, which is harmful to both patient and caregiver. (C) 2012 Elsevier B. V. All rights reserved.
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    A functional electric orthesis on the paretic leg improves quality of life of stroke patients
    (Academia Brasileira de Neurologia - ABNEURO, 2006-03-01) Fernandes, Mara Renata [UNIFESP]; Carvalho, Luciane Bizari Coin de [UNIFESP]; Prado, Gilmar Fernandes do [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    CONTEXT: Hemiparesia changes quality of life of patients with stroke making difficult a normal life. OBJECTIVE: To evaluate the effect of Functional Eletric Orthesis (FEO) applied over the paretic leg in the quality of life of stroke patients. METHOD: The quality of life of 50 stroke patients of Associacao de Assistencia a Crianca Deficiente (AACD) was evaluated with SF-36 questionnaire before and after the treatment with a FEO for rehabilitation of walking. We analyzed data according to gender and affected hemisphere. RESULTS: The average values from all domains of SF-36 improved significantly (p<0.001). Female patients improved more than male in Emotional Domain (p=0.04) and presented a trend to be better regarding Bodily Pain and Social Functioning. Patients with right hemiparesia improved more than those with left hemiparesia (p=0.02). CONCLUSION: FEO over a paretic leg is efficient to improve quality of life of stroke patients, mainly Physical Functioning.
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Health preferences measures: comparing Brazil SF-6D version with SF-36 derived versions, in patients with rheumatoid arthritis
    (Medfarma-edicoes Medicas, Lda, 2010-04-01) Campolina, Alessandro Gonçalves [UNIFESP]; Bortoluzzo, Adriana Bruscato; Ferraz, Marcos Bosi [UNIFESP]; Ciconelli, Rozana Mesquita [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Insper Inst Ensino & Pesquisa
    Objective: To compare the preference measures derived from the SF-36 by different methods, with preference measures derived from the Brazilian version of the Short Form-6 Dimensions - Brazil (SF-6D Brazil). Methods: Observational cross-sectional study. Quality of life measures were applied: HAQ, SF-36 and SF-6D. We obtained preference measures derived from the SF-36 in accordance to the algorithms developed by Fryback, Nichol, Lundberg and Shmueli. Descriptive statistics and correlation coefficients were used to analyze the results. Results: We studied 200 patients with rheumatoid arthritis. The SF-6D and preferences derived from the SF-36 showed significant correlations with each other, with Pearson coefficients varying from 0.69 to 0.92 (p <0.01). Conclusion: The SF-6D and the different methods of preference derivation from the SF-36 showed moderate to strong correlations between them. Both application of the SF-36, as the SF-6D, may be important sources of preference measures for the implementation of economic analysis in health.
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Physical therapy and psychological intervention normalize cortisol levels and improve vitality in women with endometriosis
    (Informa Healthcare, 2012-12-01) Petrelluzzi, Karina Friggi Sebe [UNIFESP]; Garcia, Marcia Carvalho [UNIFESP]; Petta, Carlos Alberto; Ribeiro, Daniel Araki [UNIFESP]; Oliveira-Monteiro, Nancy Ramacciotti de [UNIFESP]; Céspedes, Isabel Cristina [UNIFESP]; Spadari, Regina Celia [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade Estadual de Campinas (UNICAMP)
    There is as yet no effective treatment for endometriosis. the objective of this study was to evaluate the effectiveness of submitting women with endometriosis and chronic pelvic pain to a therapeutic protocol involving physical and psychological therapy. Twenty-six female volunteers were submitted to a treatment protocol consisting of 2.5-h sessions, once a week for 10 weeks. We applied a Visual Analogue Scale, the Perceived Stress Questionnaire (PSQ), and the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). Morning, afternoon, and evening levels of cortisol were determined in saliva samples. the PSQ scores were significantly lower after treatment, whereas the scores for the SF-36 vitality and physical functioning domains were significantly higher. Salivary cortisol levels were higher after treatment in the samples collected in the morning, but not in those collected in the afternoon or evening. the post-treatment cortisol levels were similar to those reported for healthy women. There were positive correlations between vitality, role emotional, social functioning, and mental health, and negative correlations to perceived stress. in conclusion, the physical and psychological intervention protocol applied in this study to women suffering of endometriosis was effective in reducing perceived stress, normalizing cortisol levels, increasing vitality and improving physical functioning.
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Qualidade de vida em pacientes com osteoporose: correlação entre OPAQ e SF-36
    (Sociedade Brasileira de Reumatologia, 2006-10-01) Lemos, Maria Carolina Davel; Miyamoto, Samira Tatiyama [UNIFESP]; Valim, Valeria [UNIFESP]; Natour, Jamil [UNIFESP]; PRO-NUCLEAR; Universidade Federal de São Paulo (UNIFESP)
    OBJECTIVE: to correlate the quality of life assessment instrument, specific to osteoporosis, OPAQ (Osteoporosis Assessment Questionnaire), with the generic instrument SF-36 (Item Short Form Health Survey). PATIENTS AND METHODS: the cross sectional observational study included 40 female patients older than 60 years with osteoporosis. A single assessment was always conducted by the same evaluator. For the statistics analisys the Pearson s coefficient and the factor analysis to OPAQ were used. RESULTS: there was a correlation between the domains and final components of SF-36 with the domains of OPAQ. The higher coefficients were between the OPAQ Symptoms and some domains of SF-36: pain (r=-0,6), social aspects (r=-0,6) and mental health (r=-0,5). Almost every aspect of SF-36 was correlated with the OPAQ Symptoms. By factor analysis of OPAQ it was observed that the 18 components of OPAQ represented 63% of factor load, and they explained the total account of osteoporosis s impact in the quality of life and were grouped in five factors: factor 1 (mobility, self-care, independence and household tasks), factor 2 (flexibility, transfers and sleep), factor 3 (backache, pain related to osteoporosis, fatigue and mood), factor 4 (fear of fall, social activity, family support and tension) and factor 5 (walking and bending, body image and work). CONCLUSION: the expected correlation was achieved between SF-36 and OPAQ, wich is a specific assessment instrument capable of assessing particular and general aspects of the quality of life in patients with osteoporosis.
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Quality of life at the initiation of maintenance dialysis treatment - a comparison between the SF-36 and the KDQ questionnaires
    (Kluwer Academic Publ, 2000-02-01) Neto, JFR; Ferraz, M. B.; Cendoroglo, M.; Draibe, S.; Yu, L.; Sesso, R.; Universidade Federal de São Paulo (UNIFESP)
    Objective: To evaluate the construct validity of the Medical Outcomes Study Questionnaire 36-Item Short Form Health Survey (SF-36) and to assess the quality of life of patients with end-stage renal disease (ESRD) at the initiation of maintenance dialysis treatment. Methods: Cross-sectional study. Setting: Eight ambulatory dialysis units in São Paulo city, Brazil. Study participants: Eighty ESRD patients at the initiation of chronic dialysis program and consecutively accepted for treatment in selected units in 1998. Main outcome measures: Quality of life as measured by the dimensions of the SF-36 questionnaire. the 'Kidney Disease Questionnaire' was used in a subgroup of patients to evaluate the validity of the SF-36. Results: Median (range) scores of the SF-36 dimensions (ranging from 0 to 100, higher scores representing better quality of life) were: Physical Function 70 (0-100), Role Limitations due to Physical Problems 25 (0-100), Bodily Pain 62 (0-100), General Health 57 (5-100), Vitality 55 (10-100), Social Function 63 (0-100), Role Limitations due to Emotional Problems 34 (0-100) and Mental Health 68 (0-100). SF-36 dimensions correlated significantly with those of the 'Kidney Disease Questionnaire' (correlation coefficients ranging from 0.23 to 0.68). Conclusions: the SF-36 was shown to have construct validity when used in patients with ESRD in Brazil. the quality of life of ESRD patients is impaired at the initiation of dialysis treatment and this was clearly evidenced in the Role Limitations due to Physical Function and Emotional Function items. Greater attention should be given to interventions that could improve the quality of life parameters at the initiation of dialysis treatment.
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Quality of life in patients with chronic kidney disease
    (Faculdade de Medicina / USP, 2011-01-01) Cruz, Maria Carolina [UNIFESP]; Andrade, Carolina [UNIFESP]; Urrutia, Milton [UNIFESP]; Draibe, Sergio Antonio [UNIFESP]; Nogueira-Martins, Luiz Antonio [UNIFESP]; Sesso, Ricardo de Castro Cintra [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    AIM: To compare the dimensions of quality of life in the stages of chronic kidney disease and the influence of sociodemographic, clinical and laboratory data. INTRODUCTION: The information available on the quality of life of patients on conservative treatment and the relationship between the quality of life and glomerular filtration rate is limited. METHODS: 155 patients in stages 1-5 of chronic kidney disease and 36 in hemodialysis were studied. Quality of life was rated by the Medical Outcomes Study Short Form 36-Item (SF-36) and functional status by the Karnofsky Performance Scale. Clinical, laboratory and sociodemographic variables were investigated. RESULTS: Quality of life decreased in all stages of kidney disease. A reduction in physical functioning, physical role functioning and in the physical component summary was observed progressively in the different stages of kidney disease. Individuals with higher educational level who were professionally active displayed higher physical component summary values, whereas men and those with a higher income presented better mental component summary values. Older patients performed worse on the physical component summary and better on the mental component summary. Hemoglobin levels correlated with higher physical component summary values and the Karnofsky scale. Three or more comorbidities had an impact on the physical dimension. CONCLUSION: Quality of life is decreased in renal patients in the early stages of disease. No association was detected between the stages of the disease and the quality of life. It was possible to establish sociodemographic, clinical and laboratory risk factors for a worse quality of life in this population.
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    QUALITY OF LIFE IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS IN NORTHEASTERN BRAZIL: IS HEALTH-RELATED QUALITY OF LIFE A PREDICTOR OF SURVIVAL FOR THESE PATIENTS?
    (Medfarma-edicoes Medicas, Lda, 2009-04-01) Freire, Eutilia Andrade Medeiros [UNIFESP]; Bruscato, Adriana; Ciconelli, Rozana Mesquita [UNIFESP]; Univ Fed Paraiba; Universidade Federal de São Paulo (UNIFESP); IBMEC; Universidade de São Paulo (USP)
    Objective: To identify social, demographic and clinical characteristics that influence survival of patients with systemic lupus erythematosus (SLE).Methods: Sixty-three patients with a diagnosis of SLE were studied at our medical services in 1999 and then reviewed in 2005. We utilized a protocol to obtain demographic and clinical traits, activity and damage indices, and health-related quality of life via the SF-36. All statistical tests were performed using a significance level of 5%.Results: Out of the 63 patients examined in 1999, six died, four were lost for the follow-up and the previous protocol was applied to the remaining 53 patients. The six patients who died presented the worst recorded health-related quality of fife, in all aspects. The most important observed predictor of death was a mean lower score in the Role-Emotional Domain of the mental health component of the SF-36 (p<0.01).Conclusion: Health-related quality of life may be used as possible predictive factor of mortality among patients with SLE.
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Quality of Life in the Surgical Treatment of Gynecomastia
    (Springer, 2009-07-01) Santana Davanco, Ricardo Augusto [UNIFESP]; Sabino Neto, Miguel [UNIFESP]; Garcia, Elvio Bueno [UNIFESP]; Matsuoka, Priscila Katsumi [UNIFESP]; Rodrigues Huijsmans, Juliana Perez [UNIFESP]; Ferreira, Lydia Masako [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Gynecomastia has an incidence of up to 60% of adolescents, causing pain and self-image disorders for the patient, leading to emotional and physical problems that can be reversed with treatment. This prospective case control study assessed the surgical treatment of gynecomastia and its impact on quality of life.Thirty-three patients aged 18-50 years and with 2-21 years of gynecomastia progression were included in the study. Adenectomy was performed. Preoperatively and 6 months postoperatively, patients completed the Brazilian version of the Short-Form 36 (SF-36) quality of life questionnaire.There was improvement in the SF-36 domains of General Health, Functional Capacity, Social Aspects, Vitality, and Mental Health.The Short-Form 36 questionnaire demonstrated that surgical treatment of gynecomastia afforded positive changes in quality of life.
  • Imagem de Miniatura
    Item
    Acesso aberto (Open Access)
    Quality of life scores differs between genotypic groups of patients with suspected hereditary hemochromatosis
    (Biomed Central Ltd, 2018) Silva Fonseca, Paula Fernanda; Cancado, Rodolfo Delfini; Naoum, Flavio Augusto; Dinardo, Carla Luana; Hencklain Fonseca, Guilherme Henrique; Menosi Gualandro, Sandra Fatima; Krieger, Jose Eduardo; Pereira, Alexandre Costa; Brissot, Pierre; Junior Lima Santos, Paulo Caleb [UNIFESP]
    Background: Hereditary hemochromatosis (HH) encompasses a group of autosomal recessive disorders mainly characterized by enhanced intestinal absorption of iron and its accumulation in parenchymal organs. HH diagnosis is based on iron biochemical and magnetic resonance imaging (MRI) assessment, and genetic testing. Questionnaires, such as SF-36 (short form health survey), have been increasingly used to assess the impact of diseases on the patient's quality of life (QL). In addition, different genotypes are identified as results of genetic tests in patients with suspected primary iron overload. In the present study, our aim was to evaluate whether domains of QL are different according to genotypic groups in patients suspected of HH. Methods: Seventy-nine patients with primary iron overload were included and two genotypic groups were formed (group 1: homozygous genotype for the HFE p.Cys282Tyr mutation
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Salivary cortisol concentrations, stress and quality of life in women with endometriosis and chronic pelvic pain
    (Informa Healthcare, 2008-01-01) Petrelluzzi, Karina Friggi Sebe; Garcia, Marcia Carvalho; Petta, Carlos Alberto; Grassi-Kassisse, Dora Maria; Spadari-Bratfisch, Regina Celia [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade Estadual de Campinas (UNICAMP)
    The objective of this study was to evaluate the perceived stress index, quality of life, and hypothalamus-pituitary-adrenal axis activity in women with endometriosis and chronic pelvic pain. for the study, 93 women with endometriosis and 82 healthy women volunteered. the visual analogue scale (VAS) (0 = no pain; 10 = severe pain) was used to determine pain intensity; the perceived stress questionnaire (PSQ) defined stress index, and the health-related quality-of-life (HRQOL)-SF-36 questionnaire was used to evaluate quality of life. Salivary cortisol was measured at 0800, 1600, and 2000h and the awakening cortisol response was assessed to evaluate the hypothalamus-pituitary-adrenal axis activity. the results show that women with endometriosis and chronic pelvic pain of moderate intensity (4.1 +/- 0.58, mean +/- SEM) have higher levels of perceived stress (0.55 +/- 0.01 versus 0.42 +/- 0.01, p < 0.05), a poorer quality of life expressed as lower scores for all items of the inventory and hypocortisolism. Lower levels of salivary cortisol were observed in all three samples collected, as well as in the awakening cortisol response, for women with endometriosis (0.19 +/- 0.09 mu g/dl) when compared with controls (0.78 +/- 0.08 mu g/dl, p < 0.051), and it was independent of pain intensity and Mental health (MH) scores in SF-36. We concluded that women with endometriosis and chronic pelvic pain show low concentrations of salivary cortisol and a high level of perceived stress, associated with a poor quality of life. Whether the hypocortisolism was an adaptive response to the aversive symptoms of the disorder or a feature related to the etiology of endometriosis remains to be elucidated.
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Salivary cortisol, stress, and health in primary caregivers (mothers) of children with cerebral palsy
    (Elsevier B.V., 2011-07-01) Bella, Geruza Perlato [UNIFESP]; Garcia, Marcia Carvalho [UNIFESP]; Spadari-Bratfisch, Regina Celia [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade Estadual de Campinas (UNICAMP)
    This study evaluated level of salivary cortisol and perceived burden, stress and health of mothers and primary caregivers of children (4-11 years of age) with cerebral palsy (purpose group, n = 37) and those for mothers of children of the same age without developmental problems (control group, n = 38). Anthropometric and socioeconomic data were collected from the participants, who also completed the perceived stress questionnaire, the Burden Interview and the 36-Item Short Form Health Survey (SF-36). Cortisol level was assayed in saliva samples collected at various times in a single day and the area under the cortisol curve was then determined. Both groups presented low socioeconomic level and high, although equivalent, perceived stress index. However, the purpose group showed lower cortisol levels, as well as lower scores for many of the SF-36 domains related to physical well-being (physical functioning, role-physical, vitality, and general health) and social functioning. Nevertheless, bodily pain was also reported to be lower. for the control group, the area under the cortisol curve correlated negatively with mental health and social functioning. for the purpose group, where the burden is greater, no such correlation was found. It was concluded that mothers of healthy children leaving in unfavorable socioeconomic conditions face high levels of stress with the hypothalamus-pituitary-adrenal cortex axis function preserved. However, to the mothers of children with cerebral palsy, who live in even worse socioeconomic conditions and also have the burden of caring for a disabled child, the level of stress was overwhelming, to an extent that it impaired the hypothalamus-pituitary-adrenal cortex axis function, as well as reflecting negatively on certain aspects of their physical and psychological wellbeing. This must receive consideration during the treatment of the child, an approach which is in line with present day tendencies towards family-centered models of assistance to disabled children. (C) 2010 Elsevier B.V. All rights reserved.
  • Nenhuma Miniatura disponível
    Item
    Somente Metadadados
    Validity of the SF-6D index in Brazilian patients with rheumatoid arthritis
    (Clinical & Exper Rheumatology, 2009-03-01) Campolina, Alessandro Gonçalves [UNIFESP]; Bortoluzzo, Adriana Bruscato; Ferraz, Marcos Bosi [UNIFESP]; Ciconelli, Rozana Mesquita [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); IBMEC
    Objective To evaluate the construct validity of the SF-6D among a sample of Brazilian patients with rheumatoid arthritis.Methods This was a validation and cross-cultural adaptation study. Preference evaluation instruments were applied: SF-6D, EQ-5D, VAS, TTO and SG. Clinical and sociodemographic parameters were obtained. Descriptive statistics, correlation coefficients and ANOVA were used to analyze the results.Results 200 patients were evaluated, among whom the iron-completion rates were 0.5% for VAS, 1.5% for TTO and 6.5% for SG. The preferences derived from the SF-6D presented the strongest correlations with EQ-SD and HAQ, followed by VAS, TTO and SG, in decreasing order. The correlations with clinical and sociodemographic parameters were, in most cases, small. The preferences obtained with the SF-6D could discriminate patients with different HAQ levels.Conclusion The SF-6D is a valid method for measuring preferences in patients with rheumatoid arthritis in a Brazilian context.