Navegando por Palavras-chave "Needle biopsy"
Agora exibindo 1 - 5 de 5
Resultados por página
Opções de Ordenação
- ItemAcesso aberto (Open Access)Correlação do tipo de biópsia e sua validade diagnóstica nos tumores músculo-esqueléticos em distintas topografias(Sociedade Brasileira de Ortopedia e Traumatologia, 2008-02-01) Siqueira, Karina Levy [UNIFESP]; Viola, Dan Carai Maia [UNIFESP]; Garcia Filho, Reynaldo Jesus [UNIFESP]; Gracitelli, Guilherme Conforto [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)OBJECTIVE:The purpose of this study is to evaluate trephine biopsies with Jamshidi needle performed at the Oncologic Orthopedics Service at UNIFESP/EPM, in musculoskeletal tumors in different locations, in order to propose an effectiveness classification of biopsy categories. METHODS: A retrospective analysis was made of 107 patients that had been submitted to biopsy with the Jamshidi needle and later to a tumor resection followed by an anatomopathological exam of the surgical specimen. Mean age of the patients was 23.5 years (2.7 to 68.7 years). Regarding gender, 40.2% were female, and 50.8% male. In this series, 86 had bone tumor (80.4%) and 21 had soft tissue tumors (19.6%). With respect to location, tumors were found mainly in the lower limbs (72%), followed by upper limbs (22.4%), and pelvis (5.6%). A joint proposal was prepared to classify biopsy categories according to the excellent, good, regular, and poor result. RESULTS: General data analysis showed excellent results in 80.4% of the biopsies, good results in 8.4%, regular in 2.8%, and poor in 8.4%. Adding together excellent and good results, one has 88.8% of the cases. In the series, the authors found 3.7% of complications, and in no case the biopsy served to rule out conservative surgery with preservation of the limb. CONCLUSION: Biopsies with Jamshidi needle represented quite an efficient diagnostic method for musculoskeletal lesions, with low rate of complications and good results comparable to those of open biopsies.
- ItemAcesso aberto (Open Access)Correlação entre a citologia e a histologia nas lesões intra-oculares suspeitas de malignidade(Conselho Brasileiro de Oftalmologia, 2003-06-01) Corrêa, Zélia Maria da Silva [UNIFESP]; Irion, Luciane Dreher; Augsburger, James J.; Schneider, Susan; Erwenne, Clélia Maria [UNIFESP]; Santa Casa de Porto Alegre-RS Serviço de Oftalmologia Setor de Oncologia Oftalmológica; Universidade Federal de São Paulo (UNIFESP); Laboratório Patologistas Reunidos; Universidade de Cincinnati Departamento de Oftalmologia; Universidade de Cincinnati Laboratório de Patologia OcularPURPOSE: To correlate the cytologic findings of fine-needle aspiration biopsy (FNAB) of intraocular tumors with the histopathology specimen when enucleation or tumor resection was the treatment of choice. METHODS: Retrospective analysis of 51 patientssubmitted tofine-needle aspiration biopsy for diagnostic purposes or cyto-histologic correlation. Exclusion criteria were non-solid lesions, conservative treatment and ultrasound guided biopsies. After exclusions, 20 patients with intraocular solid lesions suspected to be malignant were studied, 12 of them were females, with ages between 2 and 78 years. All biopsies were performed by the first author under direct (operating microscope) or indirect (binocular indirect ophthalmoscope) visualization. The chosen route was transaqueous for anterior segment tumors and transvitreous through the sclera for posterior segment tumors except cases with suspicion of retinoblastoma biopsied through the peripheral cornea. Two samples were obtained from different areas of the tumor, in all cases with a 25-gauge needle. After fine-needle aspiration biopsy, samples were sent for processing, fixation, and staining with the Papanicolaou and hematoxylin-eosin (HE) methods. Histology specimens were stained with hematoxylin-eosin. RESULTS: Three cases consisted of anterior segment (iris) tumors and 17 of tumors situated in the posterior segment, 3 of them retinoblastomas. Nine patients were biopsied for diagnostic purposes and 11 for cytological-histological correlation after enucleation. In only two cases, fine-needle aspiration biopsy yielded insufficient material for diagnosis that subsequently proved to be a granuloma and a melanoma. CONCLUSIONS: Fine-needle aspiration biopsy seems to be a reliable procedure based on cytological-histological correlations in the studied group.
- ItemAcesso aberto (Open Access)O diagnóstico do carcinoma metastático de coróide pela biópsia aspirativa com agulha fina (BAAF): relato de caso(Conselho Brasileiro de Oftalmologia, 2003-01-01) Corrêa, Zélia Maria da Silva [UNIFESP]; Irion, Luciane Cristina Dreher; Marcon, Ítalo Mundialino; Goldhardt, Raquel; Travi, Giovanni Marcos; Universidade Federal de São Paulo (UNIFESP); Fundação Faculdade Federal de Ciências Médicas de Porto Alegre; Serviço de Oftalmologia da Santa Casa de Porto Alegre; Santa Casa de Porto AlegrePURPOSE: To report a case of a patient with lung carcinoma in which the first detected metastasis was to the choroid, how it was diagnosed and confirmed. METHODS: A 35 year-old white male, while being treated for a solitary pulmonary condensation, reported sudden loss of vision, pain, discharge and red eye (right eye) for 10 days. During the ophthalmic examination a nonregmatogenous retinal detachment as well as multiple choroidal tumors were confirmed by diagnostic ocular ultrasound. Fine-needle aspiration biopsy (FNAB) was suggested to diagnose a possible metastatic disease. Fine-needle aspiration biopsy was performed under peribulbar anesthesia with sedation. A transvitreous route was chosen through a sclerotomy 4 mm from the limbus. The procedure was monitored via binocular indirect ophthalmoscopy. Two sample aspirates were obtained from different tumour foci. After fine-needle aspiration biopsy, the aspirates were sent for processing, fixation and stained with Papanicolaou and HE. RESULTS: Cytology confirmed the diagnosis of multiple metastatic tumors. Immunocytochemistry of ocular and lung aspirates revealed a common cell origin by a pankeratin (AE1/AE3) positive test. Regardless of systemic treatment with chemotherapy and improvement of the ocular status, the patient died 4 months after cytological diagnosis of metastatic carcinoma of the choroid. CONCLUSIONS: Fine-needle aspiration biopsy was efficient to diagnose and correlate ocular cytology with the primary tumor by imunohistochemical methods in this case. Fine-needle aspiration biopsy should still be used only in selected cases and further research will be necessary for it to become a standard diagnostic procedure in ophthalmology.
- ItemAcesso aberto (Open Access)Nódulo tireoidiano Bethesda III: cirurgia x observação(Universidade Federal de São Paulo (UNIFESP), 2016-10-31) Bastos Filho, Luiz de Castro [UNIFESP]; Cervantes, Onivaldo [UNIFESP]; http://lattes.cnpq.br/2752448898797822; http://lattes.cnpq.br/8186999107301095; Universidade Federal de São Paulo (UNIFESP)Objectives: To determine the characteristics of the patients, both those who were operated as those followed clinically, considering the surgical criteria and correlate the puncture findings (especially in relation to the presence or absence of nuclear atypia in the sample) and sonographic findings with histopathological examinations. Methods: Eight hundred and three (803) patients underwent fine-needle aspiration (FNA) of thyroid nodules, totaling one thousand three hundred and seventy five (1375) punctures, in the years 2011, 2012 and 2013 in a thyroid disease treatment project in partnership between the UNIFESP / EPM and the Albert Einstein Hospital. Eighty-nine patients (11%) had at least one Bethesda III thyroid nodule. Only fifty-four (7%) met the inclusion criteria. Results: Of the fifty-four patients evaluated, 50 (92.5%) were female with a mean age 48.7 [19-83] years. Thirty-four (63%) patients had multinodular glands, four of them people with hyperthyroidism and twenty (37%) presented glands with single nodule. Twenty-five (46.3%) patients were operated after first FNA. Of these, fourteen (56%) were malign and eleven (44%) were benign. Twenty-nine (53.7%) patients were observed and repeted the FNA. Fourteen (48.3%) were operated showing malignancy in 6 (42.8%) and benign histopathological result in 8 (57.2%). Fifteen (48%) patients had benign report after the new FNA being referred for follow-up. Among the sonographic findings with low or very low suspicion, the majority (19) had benign histopathology report (45.2%). The quantitative reports with malignant results were higher in cases with nuclear atypia present, totaling 8 nodules (19.0%). However, associations were not identified between the results of histopathological reports and sonographic findings (p = 0.322) or the presence of nuclear atypia (p = 0.273; x² = 1.201, gl = 1). Conclusion: Data from this study show a higher incidence of malignancy in Bethesda III nodules than that described in the Bethesda System publication article and made clear the difficulty of maintaining following several patients and conclud that, although each one of these patients require careful analysis based on clinical, ultrasound and cytological findings, there should be more liberal in surgical indication and encouragement to follow-up by the medical team.
- ItemAcesso aberto (Open Access)O uso da biópsia aspirativa com agulha fina (BAAF) no diagnóstico de lesão iriana suspeita: relato de caso(Conselho Brasileiro de Oftalmologia, 2001-08-01) Corrêa, Zélia Maria da Silva [UNIFESP]; Marcon, Ítalo Mundialino [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Faculdade Federal de Ciências Médicas de Porto AlegreTo report the case of a patient who presented with a solid anterior segment intraocular mass in his right eye, and the diagnostic investigation chosen by the authors. Diagnostic uncertainty and patient's refusal to agree with the treatment caused the authors to perform a fine needle aspiration biopsy of the lesion. Biopsy was performed by corneal puncture, through the aqueous and the tumor. Cytology of the specimen obtained by the biopsy determined the therapeutic strategy for this case. Cytology diagnosis was consistent with primary malignant melanoma of the choroid of mixed cell type. Enucleation of the eye was suggested due to the position of the tumor and its potential to spread distant metastases. After enucleation, anatomopathological examination of the eye presented a similar result to cytology. The patient is currently been followed, with no signs of metastasis 2 years after enucleation.