Navegando por Palavras-chave "Mouth neoplasms"

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    Dietary patterns and risk of oral cancer: a case-control study in São Paulo, Brazil
    (Faculdade de Saúde Pública da Universidade de São Paulo, 2007-02-01) Marchioni, Dirce Maria Lobo; Fisberg, Regina Mara; Góis Filho, José Francisco de; Kowalski, Luiz Paulo [UNIFESP]; Carvalho, Marcos Brasilino de; Abrahão, Márcio [UNIFESP]; Latorre, Maria Do Rosário Dias de Oliveira; Eluf-Neto, José; Wünsch Filho, Victor; Universidade de São Paulo (USP); Instituto do Câncer Arnaldo Vieira de Carvalho Departamento de Cabeça e Pescoço; Hospital do Câncer A.C.Camargo Departamento de Cabeça, Pescoço e Otorrinolaringologia; Hospital Heliópolis Departamento de Cabeça e Pescoço; Universidade Federal de São Paulo (UNIFESP)
    OBJECTIVE: To analyze the association between dietary patterns and oral cancer. METHODS: The study, part of a Latin American multicenter hospital-based case-control study, was conducted in São Paulo, Southeastern Brazil, between November 1998 and March 2002 and included 366 incident cases of oral cancer and 469 controls, frequency-matched with cases by sex and age. Dietary data were collected using a food frequency questionnaire. The risk associated with the intake of food groups defined a posteriori, through factor analysis (called factors), was assessed. The first factor, labeled prudent, was characterized by the intake of vegetables, fruit, cheese, and poultry. The second factor, traditional, consisted of the intake of rice, pasta, pulses, and meat. The third factor, snacks, was characterized as the intake of bread, butter, salami, cheese, cakes, and desserts. The fourth, monotonous, was inversely associated with the intake of fruit, vegetables and most other food items. Factor scores for each component retained were calculated for cases and controls. After categorization of factor scores into tertiles according to the distribution of controls, odds ratios and 95% confidence intervals were calculated using unconditional multiple logistic regression. RESULTS: Traditional factor showed an inverse association with cancer (OR=0.51; 95% CI: 0.32; 0.81, p-value for trend 0.14), whereas monotonous was positively associated with the outcome (OR=1.78; 95% CI: 1.78; 2.85, p-value for trend <0.001). CONCLUSIONS: The study data suggest that the traditional Brazilian diet, consisting of rice and beans plus moderate amounts of meat, may confer protection against oral cancer, independently of any other risk factors such as alcohol intake and smoking.