Navegando por Palavras-chave "Lutein"
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- ItemAcesso aberto (Open Access)Conceitos atuais e perspectivas na prevenção da degeneração macular relacionada à idade(Sociedade Brasileira de Oftalmologia, 2008-06-01) Torres, Rogil José De Almeida [UNIFESP]; Précoma, Dalton Bertolim; Maia, Maurício [UNIFESP]; Kaiber, Flávia; Prim, Camila; Luchini, Andréa; Matos, Rossane Serafin; Farah, Michel Eid [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Hospital Angelina Caron; Pontifícia Universidade Católica do Paraná Departamento de Cardiologia; Hospital de Olhos Oeste Paulista Serviço de Cirurgia Vitreorretiniana; Pontifícia Universidade Católica do Paraná; Nutrimedical Curitiba; Centro Oftalmológico de CuritibaThe authors prepare a literature review about the main antioxidants used in daily practice for the prevention of age-related macular degeneration progression (AMD), emphasizing the mechanism of action of each substance as well as the possible complications related to the overuse of such components.
- ItemAcesso aberto (Open Access)Efficacy of a lutein-based dye (PhacodyneTM) for visualizing anterior capsulorhexis during cataract surgery by phacoemulsification(Conselho Brasileiro de Oftalmologia, 2014-06-01) Vianna, Lucas Monferrari Monteiro [UNIFESP]; Cohen, Marcos J. [UNIFESP]; Muccioli, Cristina [UNIFESP]; Lima Filho, Acácio Alves de Souza [UNIFESP]; Sousa-Martins, Diogo [UNIFESP]; Maia, Maurício [UNIFESP]; Belfort, Rubens Junior [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Objetivos: Avaliar a eficácia e eficiência de um novo corante à base de luteína para coloração da cápsula anterior durante cirurgia de facoemulsificação em humanos. Métodos: Vinte e cinco olhos de 25 pacientes foram operados por 25 cirurgiões diferentes que realizaram capsulorrexis circular contínua e facoemulsificação após coloração da cápsula anterior com corante à base de luteína. Um questionário avaliou a opinião dos cirurgiões sobre a eficácia do corante. Exames pós-operatórios foram realizados nos dias 1, 7 e 30 por meio de exame oftalmológico completo, topografia/ paquimetria e contagem de células endoteliais. Resultados: De acordo com o questionário aplicado, o corante facilitou a cirurgia em todos os olhos. A classificação da catarata de acordo com o LOCS III foi de 3,24 ± 1,12. A acuidade visual pré-operatória com melhor correção foi de 0,89 ± 0,59 (logMAR), passando a 0,23 ± 0,22 no pós-operatório. A pressão intraocular (PIO) permaneceu estável e houve reação de câmara leve que desapareceu em todos os casos durante os primeiros 7 dias de pós-operatório. Não houve significância estatística comparando a paquimetria e PIO pré e pós-operatórios. Conclusão: O novo corante se mostrou eficiente e sem sinais de toxicidade ou efeitos adversos, após 30 dias, quando usado para auxiliar a cirurgia de facoemulsificação.
- ItemAcesso aberto (Open Access)Fatores modificáveis da degeneração macular relacionada à idade(Conselho Brasileiro de Oftalmologia, 2009-06-01) Torres, Rogil José De Almeida [UNIFESP]; Maia, Maurício [UNIFESP]; Muccioli, Cristina [UNIFESP]; Winter, Guilherme; Souza, Greyce Kelly De; Pasqualotto, Luca Rodrigo; Luchini, Andréa; Précoma, Dalton Bertolim; Hospital Angelina Caron; Universidade Federal de São Paulo (UNIFESP); Hospital de Olhos Oeste Paulista Serviço de Cirurgia Vitreorretiniana; Pontifícia Universidade Católica do Paraná; PUCPR; Centro Oftalmológico de Curitiba; PUCPR Departamento de CardiologiaThe authors present the main modifiable risk factors that may trigger and/or worsen age-related macular degeneration. Mechanisms of action related to these factors as well as preventive measures and intervention effectiveness are discussed.
- ItemSomente MetadadadosAn intraocular dye solution based on lutein and zeaxanthin in a surrogate internal limiting membrane model: A Langmuir monolayer study(Elsevier B.V., 2013-07-01) Caseli, Luciano [UNIFESP]; Sousa-Martins, Diogo [UNIFESP]; Maia, Mauricio [UNIFESP]; Lima-Filho, Acacio Alves de Souza [UNIFESP]; Rodrigues, Eduardo Buchele [UNIFESP]; Belfort, Rubens Junior [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Investigating the role of biomolecules and bioactive molecules associated With membranes is fundamental to comprehend at the molecular point-of-view biochemical and clinical processes that occur at biointerfaces. in this paper we exploit the interaction of an intraocular dye solution based on lutein and zeaxanthin in surrogate internal limiting membrane (ILM) models, consisting of dipalmitoyphosphatidylcholine (DPPC) Langmuir monolayers, pure or mixed with collagen, proteoglycan and laminin. the interactions between the film components occurring at the air-water interface were investigated with surface pressure-area isotherms and polarization modulation infrared reflection-absorption spectroscopy (PM-IRRAS). A natural dye solution based on lutein and zeaxanthin, employed to label ILM in ophthalmic surgery, was incorporated in the ILM model, and the data suggested non-rupture of the structure of the membrane, with predominance of interactions based on intermolecular forces. (C) 2013 Elsevier B.V. All rights reserved.
- ItemAcesso aberto (Open Access)Pigmentos maculares(Conselho Brasileiro de Oftalmologia, 2009-12-01) Canovas, Renata; Cypel, Marcela [UNIFESP]; Farah, Michel Eid [UNIFESP]; Belfort, Rubens Junior [UNIFESP]; ABC Faculdade de Medicina; Universidade Federal de São Paulo (UNIFESP)Lutein and Zeaxanthin are yellow pigments located at the macula. Because of your location macular pigments decrease and filter the amount of blue light that reach photoreceptors, protect the outer retina from oxidative stress and may improve the vision quality. This is a review regarding incorporation mechanism, function and knowledge update.
- ItemSomente MetadadadosSoluble lutein in combination with brilliant blue as a new dye for chromovitrectomy(Springer, 2014-07-01) Badaro, Emmerson [UNIFESP]; Furlani, Bruno [UNIFESP]; Prazeres, Juliana [UNIFESP]; Maia, Mauricio [UNIFESP]; Souza Lima, Acacio Alves [UNIFESP]; Sousa-Martins, Diogo [UNIFESP]; Muccioli, Cristina [UNIFESP]; Adami Lucatto, Luiz Filipe [UNIFESP]; Belfort, Rubens Junior [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)A new dye for vitreoretinal surgery comprised of soluble lutein/zeaxanthin 1 % and brilliant blue 0.025 % is advantageous compared with other dyes currently used for chromovitrectomy, and showed no signs of toxicity at 1 month of follow-up.To evaluate the feasibility and safety of a dye [soluble lutein/zeaxanthin (LZ) 1 % and brilliant blue (BB) 0.025 %] for improving removal of vitreous, epiretinal membranes (ERM), and internal limiting membranes (ILM) in humans.We prospectively evaluated 18 eyes treated surgically for a macular hole or ERM. Eighteen surgeons performed chromovitrectomy using the dye, and completed a questionnaire to evaluate the efficacy and safety of the dye. . Examinations included best-corrected visual acuity and intraocular pressure measurements and optical coherence tomography, fluorescein angiography, and autofluorescence performed at baseline and days 1, 7, and 30 postoperatively.The green dye was deposited on the posterior pole; vigorous dye flushing into the vitreous cavity was unnecessary. All surgeons reported that the ILM stained greenish-blue; 94.4 % reported ILM peeling adequate; the ERM stained poorly. No evidence of toxicity was observed.The new dye deposited on the posterior pole due to its higher density. the ability to stain the ILM was similar to BB. the new dye has ability to stain the vitreous, hyaloid, and especially the ILM satisfactorily. the new dye may be useful during chromovitrectomy.