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- ItemAcesso aberto (Open Access)Adiponectin complexes composition in Japanese-Brazilians regarding their glucose tolerance status(Biomed Central Ltd, 2013-04-09) Crispim, Felipe [UNIFESP]; Vendramini, Marcio F. [UNIFESP]; Moises, Regina S. [UNIFESP]; Japanese Brazilian Diabetes Study Group; Universidade Federal de São Paulo (UNIFESP)Background: Adiponectin circulates in different multimer complexes comprised of low molecular weight trimeric form (LMW), hexamer of middle molecular weight (MMW) and high molecular weight multimers (HMW). in Japanese-Brazilians, a population with high prevalence of glucose metabolism disturbances, we examined the associations of total adiponectin and its multimers with diabetes mellitus.Methods: Two study groups were examined: 26 patients with diabetes mellitus (DM, 14 women and 12 men, aged 55.3 +/- 8.6 years) and 27 age-matched control subjects with normal glucose tolerance (NGT, 12 women and 15 men, aged 54.0 +/- 9.2 years).Results: We found no significant differences in total [NGT: 6.90 ug/ml (4.38-13.43); DM: 5.38 ug/ml (3.76-8.56), p = 0.35], MMW [NGT: 2.34 ug/ml (1.38-3.25); DM: 1.80 ug/ml (1.18-2.84), p = 0.48] or LMW adiponectin [NGT: 2.07 ug/ml (1.45-3.48), DM: 2.93 ug/ml (1.78-3.99), p = 0.32] between groups. in contrast, HMW adiponectin levels were significantly lower in patients with DM [TGN: 2.39 ug/ml (1.20-4.75); DM: 1.04 ug/ml (0.42-1.60), p = 0.001]. A logistic regression analysis was done to identify independent associations with diabetes mellitus. the results showed that HOMA-IR and HMW adiponectin in women were independently associated with diabetes mellitus.Conclusion: the current investigation demonstrates that in Japanese-Brazilians HMW adiponectin is selectively reduced in individuals with type 2 diabetes, while no differences were found in MMW and LMW adiponectin isoforms.
- ItemSomente MetadadadosAnalysis of criteria for metabolic syndrome in a population-based study of Japanese-Brazilians(Blackwell Publishing, 2005-07-01) Rosenbaum, P.; Gimeno, SGA; Sanudo, A.; Franco, L. J.; Ferreira, SRG; Japanese-Brazilian Diabetes Grp; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)Objective: Criteria for metabolic syndrome (MS) differ particularly regarding the definition of central obesity and consequently, there could be differences in the assessment of cardiovascular risk. We estimated the prevalence of metabolic syndrome, compared the agreement of the World Health Organization (WHO) criteria with the standard and a modified National Cholesterol Education Program (NCEP) criterion and investigated whether additional factors were associated with the diagnosis of the syndrome in a Japanese descendant population.Methods: in this cross-sectional, population-based survey, 1166 Japanese-Brazilians (533 men, 633 women) aged 57.4 +/- 12.4 years with mean body mass index (BMI) and waist of 25.2 +/- 4.0 kg/m(2) and 84.5 +/- 10.6 cm, respectively, were included. McNemar and kappa statistics were used to assess the concordance between WHO criteria with the standard and a modified NCEP criteria (waist of 90 and 80 cm, for men and women, respectively). in logistic regression analysis, a number of metabolic variables and albumin-to-creatinine ratio were included to test independent associations with metabolic syndrome defined by the modified NCEP criteria.Results: According to WHO, 55.4% (95% Cl 52.5-58.2%) of the subjects had MS and to NCEP 47.4% (95% Cl 44.6-50.0%). WHO criterion detected 48.3% of central obese subjects while NCEP only 14.0%. Kappa statistics showed a good strength of agreement (k = 0.67, p < 0.01) between WHO and NCEP standard definitions of MS. Using the modified NCEP criterion for Asians, more subjects with metabolic syndrome were identified (58%) and agreement with WHO was improved (k = 0.72, p < 0.001). However, similar Framingham risk scores were attributed to the subsets of subjects classified by any of the three criteria. Areas under the receiver operating characteristic curves, obtained for the modified waist values to diagnose metabolic syndrome according to WHO, were > 0.80 and corresponded, respectively, to sensitivity and specificity of 63 and 83% for men and 77 and 72% for women. in final logistic regression model, age, male sex, BMI and homeostasis model assessment-insulin resistance but not with albumin-to-creatinine ratio (ACR) were independently associated with the syndrome.Conclusions: High prevalence of MS, independent of the criterion considered, was found in this Japanese-Brazilian population. the replacement of waist cutoff by those proposed by WHO for Asians lead to this diagnosis in a higher number of subjects with elevated cardiovascular risk. Our data did not support that ACR should be included in the classical definition of MS in Japanese descendants as previously suggested by WHO.
- ItemAcesso aberto (Open Access)Assessing food dietary intakes in Japanese-Brazilians using factor analysis(Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, 2010-11-01) Gimeno, Suely Godoy Agostinho [UNIFESP]; Andreoni, Solange [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Franco, Laercio Joel [UNIFESP]; Cardoso, Marly Augusto; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)We describe the use of factor analysis for assessing food habits in Japanese-Brazilians. Dietary data from 1,283 participants of a cross-sectional study were used. Besides statistical criteria, we also used the conceptual meaning of identified profiles to obtain scores for dietary patterns (Japanese or Western profile). Paired Student t test, linear regression and Poisson models were used to verify the existence of relationship between these scores and generation, body mass index (BMI), waist circumference and presence of metabolic syndrome, respectively. First generation subjects had higher mean Japanese profile scores and lower Western profile scores than those of second generation. The Western dietary pattern was associated with BMI (p = 0.001), waist circumference (p = 0.023) and metabolic syndrome (p < 0.05). We concluded that these scores were able to discriminate subjects who maintained their traditional Japanese lifestyle or otherwise, and that the incorporation of a Western lifestyle is associated to high values of BMI, waist circumference and presence of metabolic syndrome.
- ItemAcesso aberto (Open Access)Associação entre consumo de alimentos embutidos e obesidade em um estudo de base populacional de nipo-brasileiros(Sociedade Brasileira de Endocrinologia e Metabologia, 2013-08-01) Cristofoletti, Maria Fernanda; Gimeno, Suely Godoy Agostinho [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Cardoso, Marly Augusto; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)OBJECTIVE: The aim of this study was to investigate the association between the consumption of processed meat with overall, abdominal, and overall with abdominal obesity in a Japanese-Brazilian population, which is known to be at cardiometabolic risk. SUBJECTS AND METHODS: A total of 329 men and 443 women aged ≥ 30 years were evaluated in a cross-sectional population-based survey. Diagnosis of overall obesity and abdominal obesity were based on the World Health Organization (WHO) criteria for Asians. Food intake was assessed by a validated food frequency questionaire. RESULTS: In men, processed meat intake was positively associated with overall with abdominal obesity (OR 2.97; 95%CI 1.13-7.78) after adjustment. In women, only the red meat group was associated with overall with abdominal obesity after adjustment (OR 0.47, 95%CI 0.23-0.96). CONCLUSION: Our results showed that high intakes of processed meats were associated with overall with abdominal obesity in male Japanese-Brazilians, but not in females.
- ItemAcesso aberto (Open Access)Consumo alimentar e doença macrovascular em nipo-brasileiros: um estudo transversal(Sociedade Brasileira de Endocrinologia e Metabologia, 2009-10-01) Salvo, Vera Lúcia Morais Antonio de; Cardoso, Marly Augusto; Barros Junior, Newton de [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Gimeno, Suely Godoy Agostinho [UNIFESP]; Universidade Metodista de São Paulo; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)OBJECTIVE: To describe the food intake of Japanese-Brazilians with and without macrovascular disease (MVD). METHODS: MVD was defined, for 1,165 Japanese-Brazilians, by scores attributed to the health historical, electrocardiogram and ankle-brachial index values. The usual dietary intake was determined using a food frequency questionnaire. RESULTS: The MVD prevalence was of 3.2%, being similar among genders. Statistically higher frequencies of individuals with MVD were observed among those of first generation, with age > 60 years, tobacco user, with hypertension, hypertriglyceridemia and diabetes. Subjects with MVD were older, with smaller hip circumference, and higher systolic blood pressure levels, triglycerides and glycemia concentration; they informed higher consumption of iron source food and smaller of grains fibers. Statistically significant difference was found to saturated fat (crude analysis: second tercile versus first tercile). CONCLUSIONS: Programs of nutritional education should be stimulated in this group with high prevalence of non-communicable chronic diseases.
- ItemSomente MetadadadosDiabetes in Japanese-Brazilians - Influence of the acculturation process(Elsevier B.V., 1996-10-01) Franco, L. J.; Universidade Federal de São Paulo (UNIFESP)Epidemiologic studies of migrant populations provide very promising clues towards understanding the roles of genetics and environmental factors in the etiology of diabetes mellitus. Populations. of Japanese ancestry are of particular interest due to marked differences in prevalence rates of non-insulin dependent diabetes (NIDDM) when comparing those living in Japan with those who migrated to western countries. Brazil offers very favorable conditions to the study of diabetes in the Japanese origin population. Presently, Brazil has the largest population of Japanese ancestry outside Japan. A cross-sectional study comparing first (Issei) and second (Nisei) generations of Japanese-Brazilians living in the city of Bauru, in the industrialized stare of SBo Paulo, southeast of Brazil, was carried out between May and November 1993. the study sample consisted of all first generation (127 men and 111 women) and a random sample of second generation (136 men and 156 women) aged 40-79 years. Results show that: 1-The prevalence of diabetes in Japanese Brazilians (12.8 and 16.2% for first and second generations) are higher than the rates reported for Japan at comparable age-groups. 2-Comparing generations, the age-adjusted prevalence of diabetes was higher in the second generation only for men (men: 12.4 vs. 21.7%; women: 11.6 vs. 11.4%). 3-Obesity was more prevalent in the second generation among men (Men: 34.6 vs. 45.7%, women: 39.6 vs. 40.8%).
- ItemAcesso aberto (Open Access)Diabetes mellitus tipo 2: fatores preditivos na população nipo-brasileira(Sociedade Brasileira de Endocrinologia e Metabologia, 2003-10-01) Nascimento, Rogéria do [UNIFESP]; Franco, Laercio Joel [UNIFESP]; Gimeno, Suely Godoy Agostinho [UNIFESP]; Hirai, Amélia Toyomi [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)In order to identify the main predictors for the development of type 2 diabetes mellitus (DM2) in a population with high prevalence of DM - the Japanese-Brazilians -, we evaluated 314 individuals with Japanese ancestry from Bauru, SP, aged 40 years or more, without miscegenation, in 1993 and 2000. The parameters evaluated, obtained in 1993, were sex, age, body mass index (BMI), waist and hip circumferences, fasting and 2h after 75g of glucose load glycemia, insulinemia and proinsulinemia, HOMA (function of the b cell and insulin resistance), lipid profile and blood pressure. The glycemic homeostasis evaluated in 2000 showed that individuals with impaired fasting glycemia or impaired glucose tolerance presented a higher risk for the progression to DM2 (60 and 70%, respectively) than normals (19%). The main variables involved in the progression to DM were BMI, waist circumference (only women), systolic blood pressure, fasting and 2h glycemia, and VLDL-cholesterol. These results showed the existing potential for the reduction in the incidence of DM2 in this population, because the main risk factors can be modified by interventions in lifestyle.
- ItemSomente MetadadadosDietary intakes associated with metabolic syndrome in a cohort of Japanese ancestry(Cambridge Univ Press, 2006-09-01) Damião, Renata [UNIFESP]; Castro, Teresa G.; Cardoso, Marly A.; Gimeno, Suely Godoy Agostinho [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Japanese Brazilian Diabetes Study Group; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)The present study examined the association between dietary factors and metabolic syndrome in a 7-year follow-up of Japanese-Brazilians. in 1993, a survey estimated the prevalence of diabetes in a Japanese-Brazilian population aged 40-79 years. From 647 subjects studied at baseline, 394 (60.9 %) participated in a second survey (2000); after exclusion of subjects with self-reported diseases, 23.4 % (n 151) were included in the present analysis. Metabolic syndrome diagnosis was based on the National Cholesterol Education Program criteria modified for Asians. Food intake was assessed by a validated food-frequency questionnaire. At baseline, mean ages were 56.1 (SD 9.7) and 54.7 (SD 10.6) years for men and women, respectively. Similar cumulative incidence rates of the metabolic syndrome were found in both sexes (36.9 (95 % CI 26.6, 48.1)% for men and 38.8 (95 % CI 27.1, 51.4) % for women). in 1993, mean values of blood pressure, waist circumference for men and 2 h plasma glucose for both sexes were higher among subjects who developed metabolic syndrome when compared with those who did not. Comparisons of nutrient intakes between subsets of subjects who developed or did not develop metabolic syndrome showed an association of protein intake with the syndrome only in men (96.4 (SD 56.8) v. 74.3 (SD 26.0) g/d; P < 0.05). Odds ratios of the metabolic syndrome across tertiles of food groups intake showed that among men the highest tertile of red meat consumption was associated with a 4.7-fold increase in risk of developing the syndrome, after adjustments for confounders. However, the statistical significance of this model disappeared when saturated fatty acids were added. the data raised the possibility of a role of red meat consumption for the occurrence of metabolic syndrome in Japanese-Brazilian men. the present findings may have implications for the prevention of metabolic syndrome in this high-risk population.
- ItemAcesso aberto (Open Access)Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira(Sociedade Brasileira de Endocrinologia e Metabologia, 2008-02-01) Siqueira, Antonela F. A. [UNIFESP]; Harima, Helena A. [UNIFESP]; Osiro, Katsumi [UNIFESP]; Hirai, Amélia Toyomi [UNIFESP]; Gimeno, Suely Godoy Agostinho [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP); Japanese-Brazilian Diabetes Study GroupHigh prevalence of diabetes has been previously reported in Japanese-Brazilians. In an attempt to better estimate the cardiometabolic risk, this study evaluated lipid disorders in 1,330 Japanese-Brazilians (46% men) aged >30 years. Hypercholesterolemia was defined as serum cholesterol > 240 mg/dL, hypertriglyceridemia as values > 150 mg/dL and low-HDL-C as values <40 mg/dL and <50 mg/dl for men and women respectively. The prevalence of dyslipidemias was compared by the chi-square test between gender and glycemic category. Mean and Standard Deviation of lipids and lipoproteins were compared by the Student t-Test between gender. Hypertriglyceridemia was detected in 66.0% [95% CI: 63.5-68.5] of the population, being more common in men and increasing with deterioration of glucose metabolism. Mean level of triglycerides was 235.7±196.3 mg/dL. The prevalence of hypercholesterolemia was 24.4% [95% CI: 22.1- 26.7]. Low HDL-C was observed in 17.5% [95% CI: 14.5-20.5] of men and 43.0% [95% CI: 39.4- 46.6] of women but total / HDL-cholesterol ratio was lower in women (4.23 ± 0.68 vs. 4.40 ± 0.73, p<0.001). In Japanese-Brazilians, hypertriglyceridemia is the commonest dyslipidemia, in agreement with the high prevalence of diabetes. Men showed a worse lipid profile than women; it was suggested that the Western diet and living habits could be deteriorating their health.
- ItemAcesso aberto (Open Access)Factors associated with stages of change for red meat and vegetable intake by Japanese-Brazilians(Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, 2009-07-01) Barbieri, Patricia; Palma, Raphaela Fernanda Muniz; Nishimura, Renata Yumi; Damião, Renata [UNIFESP]; Bevilacqua, Marselle Rodrigues [UNIFESP]; Massimino, Flávia [UNIFESP]; Chain, Rita; Gimeno, Suely Godoy Agostinho [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Sartorelli, Daniela Saes; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP); Universidade Sagrado CoraçãoStages of change assess individual motivation for lifestyle changes, contributing to the development of more effective intervention strategies. The objective of the present study was to identify factors associated with stages of change for lower intake of red meat and higher intake of vegetables in a cross-sectional analysis of 578 Japanese-Brazilians aged 30-90 years. In adjusted logistic regression models, the odds ratios for women (OR = 1.89; 95%CI: 1.154; 3.103) and physically active individuals (OR = 1.00; 95%CI: 1.000; 1.001) were positively associated with stage of action for the higher intake of vegetables. Inverse associations were observed between central obesity (OR = 0.5; 95%CI: 0.351; 0.887) and highest tertile of red meat intake (OR = 0.50; 95%CI: 0.302; 0.817), as well as a positive association between age (OR = 1.04; 95%CI: 1.020; 1.070) and the stage of action to the lower intake of meat were verified. Motivation for Japanese-Brazilians to change their food intake was linked to lifestyle. Stage of change is an important factor in mediating food intake behavior change.
- ItemAcesso aberto (Open Access)Fatores associados ao consumo de frutas, verduras e legumes em Nipo-Brasileiros(Associação Brasileira de Saúde Coletiva, 2009-09-01) Palma, Raphaela Fernanda Muniz; Barbieri, Patrícia; Damião, Renata [UNIFESP]; Poletto, Juliana [UNIFESP]; Chaim, Rita; Gimeno, Suely Godoy Agostinho [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Sartorelli, Daniela Saes; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP); Universidade Sagrado Coração; Faculdade de Saúde Pública Departamento de NutriçãoThe determination of factors associated with fruit and vegetable intake is an important tool for the development of effective intervention programs aimed at increasing the consumption of these foods. The objective of the present cross-sectional study was to identify the factors associated with the adequate consumption of fruit and vegetables (> 400g/day) among 581 adult Japanese-Brazilians, 1st and 2nd generations of immigrants, living in Bauru, SP, Brazil. Food consumption was estimated using three 24-hour recalls. On adjusted logistic regression models, higher meal frequencies were associated with a better chance of adequate daily intake of fruit and vegetables [OR (95% CI)]: [1.31 (1.05, 1.63)]. Nevertheless, individuals at the highest tertile of saturated fat intake were less likely to have adequate daily intake of these foods [0.35 (0.21, 0.60)]. A trend toward adequate intake of fruit and vegetables was found among older participants. These results suggest that more intensive intervention programs are needed among young individuals with higher saturated fat intake. Moreover, higher meal frequency might promote better adherence to the goals of daily fruit and vegetable intake.
- ItemAcesso aberto (Open Access)Fatores preditores do alcance das metas de um programa de intervenção em nipo-brasileiros(Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, 2010-06-01) Camargo, Marilia Alessi Guena de; Franco, Laercio Joel [UNIFESP]; Gimeno, Suely Godoy Agostinho [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Sartorelli, Daniela Saes; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)The aim of this study was to identify baseline factors associated with achieving goals after a 12-month lifestyle intervention program in a Japanese-Brazilian population, using adjusted logistic regression models. In 2005, 321 participants were overweight. The odds [OR (IC95%)] of reaching the goals after 12 months of intervention were directly related to female gender [2.35 (1.34, 4.13)] and older age [1.03 (1.00, 1.06)] and inversely related to baseline morbidity [0.33 (0.14, 0.77)]. Of the 261 sedentary individuals, achieving the goal for physical activity was inversely related to working [0.44 (0.17, 0.95)]. No baseline predictors were found for reaching the goal of fruit and vegetable consumption or saturated fat intake after 12 months. At baseline, women, older individuals, and individuals without diseases or not working showed increased odds of achieving the goals after 12 months of the lifestyle intervention.
- ItemAcesso aberto (Open Access)Grupos de alimentos para investigação de risco para diabetes tipo 2 e doenças associadas(Associação Brasileira de Saúde Coletiva, 2011-09-01) Nishimura, Renata Yumi; Damião, Renata; Gimeno, Suely Godoy Agostinho [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Sartorelli, Daniela Saes; Universidade de São Paulo (USP); Universidade Federal do Triângulo Mineiro; Universidade Federal de São Paulo (UNIFESP)INTRODUCTION: The food groups conventionally applied in activities of nutritional counseling were established according to their macronutrient content. However, it does not consider recent scientific evidences of the association between food consumption and risk of developing non-communicable chronic diseases. OBJECTIVE: To propose food groups for the investigation of the association between food consumption and risk of developing type 2 diabetes and associated diseases among Japanese-Brazilians. METHODS: Cross-sectional analysis of baseline data of a lifestyle intervention study conducted among Japanese-Brazilians of Bauru, SP, Brazil, from 2005 to 2007. Food intake was assessed by three 24-hour recalls of 640 participants, both genders, aged 30 to 88 years old. RESULTS: Eighteen new food groups were proposed according to their quantity and quality of fat, carbohydrates, sodium, and fiber. CONCLUSION: The new food groups incorporate recent evidences of the association between diet and the risk of developing type 2 diabetes.
- ItemAcesso aberto (Open Access)Hyperuricemia and associated factors: a cross-sectional study of Japanese-Brazilians(Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, 2011-02-01) Poletto, Juliana [UNIFESP]; Harima, Helena Aiko [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Gimeno, Suely Godoy Agostinho [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)This cross-sectional study aimed to estimate the prevalence of hyperuricemia and associated risk factors among Japanese-Brazilians. We obtained data on demographic, health history, food intake, and laboratory variables. Chi-square and prevalence ratios were used as measures of association. 35.3% of the subjects presented hyperuricemia, which was more frequent in smokers, males, age > 55 years, with co-morbidities, individuals on uric acid-increasing medication, serum creatinine > 1.4mg/dL, high alcohol consumption, and low consumption of milk and dairy products. In the multivariate analysis, the associations remained significant with gender, overweight, central obesity, hypertriglyceridemia, and use of specific drugs. Among males, low intake of saturated fat was associated with hyperuricemia. Individuals with hypertension showed a negative association with dairy product consumption. The high hyperuricemia prevalence suggests that changes in nutritional profile and control of associated co-morbidities could help minimize occurrence of this condition.
- ItemSomente MetadadadosMacrovascular disease in a Japanese-Brazilian population of high prevalence of metabolic syndrome: Associations with classical and non-classical risk factors(Elsevier B.V., 2007-11-01) Siqueira, Antonela F. A.; Franco, Laercio J.; Gimeno, Suely G. A.; Matsumura, Luiza K.; Abdalla, Dulcineia S. P.; Barros, Newton de; Ferreira, Sandra R. G.; JBDSG; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)Background: the Japanese-Brazilian Diabetes Study detected high prevalence of metabolic syndrome (MS) in a population of Japanese ancestry living in Brazil. We describe the prevalence of macrovascular disease (MVD) and its association with classical and non-classical cardiovascular risk factors in this population.Methods: An overall of 1163 individuals were studied; diagnosis of MVD was based on a score obtained from medical history, ankle-brachial pressure index and electrocardiogram, defining three groups: no MVD, possible MVD and definite MVD.Results: Prevalence of MVD was 14.3% (possible MVD: 11.2%; definite MVD: 3.1%). Individuals with MS had higher rates of MVD (16.9% versus 11.2%; p < 0.05). Comparing to no MVD, age, 2 It plasma glucose, anti-LDL(+) and anti-LDL(-) levels, and urinary albumin-to-creatinine ratio were higher in both categories with MVD; waist-to-hip ratio, fasting plasma glucose, HbAlc, total-to-HDL cholesterol ratio and triglycerides were higher in that with definite MVD; systolic blood pressure and homocysteine were higher in that with possible MVD. Using logistic regression, systolic blood pressure, smoking habit and anti-LDL(+) were independently associated with MVD.Conclusion: MVD is highly prevalent in Japanese-Brazilians and its association with MS was confirmed. A novel marker of lipoprotein modifications-anti-LDL(+) antibody-could be useful in identifying individuals at higher risk. (c) 2006 Elsevier Ireland Ltd. All rights reserved.
- ItemSomente MetadadadosNutritional intervention programme among a Japanese-Brazilian community: procedures and results according to gender(Cambridge Univ Press, 2010-09-01) Damiao, Renata; Sartorelli, Daniela Saes; Hirai, Amelia [UNIFESP]; Massimino, Flavia [UNIFESP]; Poletto, Juliana [UNIFESP]; Bevilacqua, Marselle Rodrigues [UNIFESP]; Chaim, Rita; Morais Antonio de Salvo, Vera Lucia [UNIFESP]; Asakura, Leiko [UNIFESP]; Gouveia Ferreira, Sandra Roberta; Andreoni, Solange [UNIFESP]; Agostinho Gimeno, Suely Godoy [UNIFESP]; Japanese Brazilians Diabet Study G; Universidade Federal de São Paulo (UNIFESP); Triangulo Mineiro Fed Univ; Universidade de São Paulo (USP); Sagrado Coracao UnivObjective: To describe the results of a nutritional intervention programme among Japanese-Brazilians according to gender.Design: A non-controlled experimental study.Setting: the research included three points of clinical, nutritional and physical activity evaluation: at baseline (in 2005), after the first year and at the end of the second year (in 2007). the paired Student t test and multiple linear regression analysis were used to evaluate changes in the subjects' profile (clinical, nutritional and physical activity variables).Subjects: Japanese-Brazilians (n 575) of both genders, aged over 30 years.Results: We verified statistically significant reductions in body weight (0.9 kg), waist circumference (2.9 cm), blood pressure, fasting blood glucose (>3 mg/dl) and total cholesterol (>20 mg/dl) and its fractions, in both genders. We also found reductions in intake of energy (among men), protein (among women) and fat (both genders) and increases in intake of total fibre (among women) and carbohydrate (among men).Conclusions: the intervention programme indicated meaningful benefits for the intervention subjects, with changes in their habits that led to a 'healthier' lifestyle positively impacting their nutritional and metabolic profile.
- ItemSomente MetadadadosNutritional status of Japanese-Brazilian subjects: comparison across gender and generation(C A B I Publishing, 2003-05-01) Freire, Renata D. [UNIFESP]; Cardoso, M. A.; Shinzato, Alexandre R. [UNIFESP]; Ferreira, Sandra Roberta Gouvea [UNIFESP]; Japanese-Brazilian Diabet Study Group; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)The present paper describes a nutritional survey carried out among Japanese-Brazilian subjects living in Bauru, south-eastern Brazil. Data were from a cross-sectional population-based study of 1283 first-generation Japanese-Brazilian subjects (Japan-born; 127 men and 121 women) and second-generation Japanese-Brazilian subjects (Brazil-born; 456 men and 573 women) aged 30-90 years. Anthropometric measurements and % body fat were measured and BMI and waist:hip ratio calculated. Dietary assessment was performed using a validated food-frequency questionnaire. A considerable proportion of men (51 %) and women (47 %) had excess weight (BMI>24.9 kg/m(2)). A greater waist circumference in men and women (age-adjusted by covariance analysis) was observed among Brazil-born participants. in general, only 10 % of the participants reported current practice of sports or other vigorous physical activity. Age-adjusted mean energy intakes and % energy from macronutrients were found to be similar across generations. the age-adjusted mean daily % energy intake from fat were similar across generations: among Japan-born participants, they were 31.5 (95 % CI 30.6, 32.4) % for men and 32.6 (95 % CI 31.7, 33.5) % for women. the respective figures for Brazil-born subjects were 32.1 (95 % CI 31.6, 32.6) % and 33.2 (95 % CI 32.7, 33.5) %. These values are quite different from the usual intakes reported in Japan during the last decades (about 25 %). Taking into account the traditional Japanese diet, a high energy density diet and a sedentary lifestyle may be implicated in the high prevalence of central obesity and metabolic syndrome observed among Japanese-Brazilian subjects across gender and generations.
- ItemSomente MetadadadosPanic disorder cases in Japanese-Brazilians in Japan: Their ethnic and cultural confusion(Blackwell Science Asia, 2001-04-01) Tsuji, K.; Miyasaka, Lincoln Sakiara [UNIFESP]; Otsuka, K.; Honda, G.; Kato, S.; Abe, Y.; Dokkyo Univ; Universidade Federal de São Paulo (UNIFESP); Jichi Med Sch; Juntendo UnivThe comparatively high salaries made in Japan are attractive to many Japanese-Brazilians. the number of individuals from this ethnic group being treated in Japanese mental hospitals has increased. We hypothesized that Japanese-Brazilian patients with panic disorders adjusted better to Japanese society and culture than those with other mental disorders. the subjects in the present study are 40 Japanese-Brazilian patients undergoing treatment at the Department of Psychiatry at Jichi Medical School, Japan, from May 1990 to September 1998. Patients were divided into a panic disorder group, a schizophrenic group, a mood disorder group and a neurosis group. Demographic data (Japanese language ability, duration of residence in Japan etc.) were collected. A comparison was made among the four groups. Patients in the panic disorder group showed a significant tendency to be fluent speakers of Japanese. Patients in the panic disorder group also had been in Japan for a significantly longer period of time than those in the other three groups. Japanese ability and length of residence in Japan rule out exacerbating factors due to a foreign living environment. Panic disorder patients usually have resolved the problems inherent in living and working in a foreign country. in general, Japanese-Brazilians are more comfortable both financially and socially in Japan than other foreign laborers because of their cultural and family background. the emotional conflict experienced by such patients may result from concern over whether to live in Brazil or Japan in the future. Their ethnic and cultural identity may be confused, fluctuating between identifying with Brazil and with Japan, and this may cause vague feelings of anxiety.
- ItemSomente MetadadadosPlasma adiponectin levels and incident glucose intolerance in Japanese-Brazilians: A seven-year follow-up study(Elsevier B.V., 2006-09-01) Vendramini, Marcio F.; Ferreira, Sandra R. G.; Gimeno, Suely G. A.; Kasamatsu, Teresa S.; Miranda, Walkiria L.; Moises, Regina S.; Universidade Federal de São Paulo (UNIFESP)The objective of this study was to investigate whether decreased baseline adiponectin levels are an independent risk factor for development of glucose intolerance in a population-based study of Japanese-Brazilians, a group with one of the highest prevalence rates of diabetes worldwide. We examined 210 Japanese-Brazilians (97 male and 113 female, aged 56.7 +/- 10.1 years) with normal glucose tolerance (NGT). Plasma adiponectin, insulin, fasting and 2-h plasma glucose and lipid profile were evaluated at baseline and also at 7-year follow-up. Plasma adiponectin levels were significantly lower in glucose intolerance progressors compared with subjects who remained NGT. By increasing tertiles of adiponectin, the frequencies of subjects who progressed to glucose intolerance were 40%, 33% and 27% and the frequencies of subjects who remained NGT were 13%, 35% and 52% (chi = 15.8, p = 0.001). Logistic regression analyses showed that adiponectin levels (OR for the highest versus lowest tertile: 0.31; 95% Cl: 0.12-0.84, p = 0.021), male sex (OR: 2.61, 95% CI: 1.21-5.65, p = 0.015), fasting plasma glucose (OR: 3.05, 95% CI: 1.35-6.91, p = 0.008) and waist circumference (OR: 1.04, 95% Cl: 1.00-1.08, p = 0.046) were independent risk factors for the progression to glucose intolerance. in conclusion, low plasma levels of adiponectin is one of several independent predictors of glucose intolerance in a Japanese-Brazilian population. (c) 2006 Elsevier Ireland Ltd. All rights reserved.
- ItemAcesso aberto (Open Access)Prevalência de hiperuricemia e fatores nutricionais associados: um estudo transversal com nipo-brasileiros do município de Bauru(Universidade Federal de São Paulo (UNIFESP), 2009-03-25) Poletto, Juliana [UNIFESP]; Gimeno, Suely Godoy Agostinho [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)This study aimed to estimate the prevalence of hiperuricemia among Japanese-Brazilians living in Bauru city (Sao Paulo) as well to verify the existence of associations between this disease and nutritional factors. METHODS: Data were obtained from 1,330 individuals using previously tested questionnaires (demographic, health history and food intake data), physical examination (health status and blood pressure) and laboratory procedures (uric acid, creatinine, fasting and 2 h glucose, total cholesterol and fractions). Chi-square and prevalence ratios were used to evaluate associations between hyperuricemia and nutritional variables. RESULTS: The prevalence of hyperuricemia was 35.3% and it occurred more frequently among smoker individuals, men subjects, aged . 55 years, with overweight or obesity, central obesity, glucose intolerance, hypercholesterolemia, hypertrigliceridemia, using specific drugs and with creatinine levels >1.4 mg/dL. We found in the crude analysis that hiperuricemia was associated with total calories, total fat, saturated, alcohol, red and processed meats, milk and dairy products, and citric fruits intake. After control variables adjustment remained statistically significant the associations between hyperuricemia and body weight excess, central obesity, hypertrigliceridemia and use of specific drugs. CONCLUSION: High hiperuricemia prevalence rate was found among these Japanese-Brazilians and changes in nutritional profile including weight and body fat reductions may help to minimize the occurrence of this disease in that community.