Navegando por Palavras-chave "Imaging contrast"

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    Application of computed tomography images in the evaluation of magnetic nanoparticles biodistribution
    (Elsevier B.V., 2010-08-01) Dias, Argleydson Leao; Kunzel, Roseli; Levenhagen, Ronaldo Savarino [UNIFESP]; Okuno, Emico; Universidade de São Paulo (USP); Ctr Univ Franciscano; Universidade Federal de São Paulo (UNIFESP)
    In this work we evaluate the effectiveness of computed tomography images as a tool to determine magnetic nanoparticle biodistribution over biological tissues. for this purpose, tomography images for magnetic nanoparticles, composed of Fe(3)O(4), coated with 2,3-dimercaptosuccinic acid (DMSA), were generated at several material concentrations. the comparison of CT numbers, calculated from these images generated at clinical conditions, with typical CT numbers for biological tissues, shows that the detection of nanoparticle in most tissues is only possible for high material concentrations. (C) 2010 Elsevier B.V. All rights reserved.