Navegando por Palavras-chave "Fetal death"
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- ItemAcesso aberto (Open Access)Does sodium nitroprusside kill babies? A systematic review(Associação Paulista de Medicina - APM, 2007-03-01) Sass, Nelson [UNIFESP]; Itamoto, Caroline Harumi [UNIFESP]; Silva, Marina Pereira [UNIFESP]; Torloni, Maria Regina [UNIFESP]; Atallah, Álvaro Nagib [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)OBJECTIVE: To determine whether sodium nitroprusside causes fetal death in pregnancies complicated with hypertension. DATA SOURCES: Medical Literature Analysis and Retrieval System Online (MEDLINE; 1996 to 2003), Excerpta Medica (EMBASE; 1970 to 2003), Web of Science/Institute for Scientific Information (ISI; 1945 to 2003), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS; 1982 to 2003) and the Cochrane Library. REVIEW METHODS: The medical subject headings used were nitroprusside and pregnancy, hypertension or eclampsia or preeclampsia and nitroprusside and pregnancy and hypertensive emergencies. The search was limited to humans and female gender, in all fields, publication types, languages and subsets. Articles were also identified by reviewing the references of articles and textbooks on hypertension and pregnancy. RESULTS: The search located nine studies. The sum of all the publications yielded a total of 22 patients and 24 exposed fetuses (two pairs of twins). There were no randomized clinical trials and no prospective cohorts. All of the studies were observational in nature. CONCLUSIONS: At present, there is insufficient evidence for definitive conclusions about any direct association between sodium nitroprusside use and fetal demise.
- ItemAcesso aberto (Open Access)Óbito fetal em microrregião de Minas Gerais: causas e fatores associados(Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, 2003-03-01) Nurdan, Nestor [UNIFESP]; Mattar, Rosiane [UNIFESP]; Camano, Luiz [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)PURPOSE: to study the causes and associated factors of fetal death. METHODS: epidemiological descriptive study, composed of 190 cases of fetal loss amongst 11,825 pregnant women that gave birth at the two only hospitals (Casa de Saúde Divino Espírito Santo and Hospital Nossa Senhora Auxiliadora) of Caratinga City, in the State of Minas Gerais, Brazil, in the period from January 1, 1995 to April 30, 2000. The variables were the number of pregnancies, the timing of the pregnant women at the time of hospitalization, the occurrence of fetal death in relation to delivery and the cause of fetal death. Since there were no comparative groups, tables, percentages and arithmetical means were applied, following the guidelines of the Course of Statistics, of the Universidade Federal de São Paulo (UNIFESP). RESULTS: among the 189 pregnant women with fetal death, 77 were primigravidal and 76 had already been pregnant 2 to 5 times. The gestational age in 113 women was from 20 to 37 weeks. In relation to parturition, the fetal loss occurred during the antepartum period in 164 of 190 dead fetuses. The most frequently noticed death causes were: abruptio placentae in 35 cases, fetal anomaly in 12 cases, and hypertension syndrome in 8 cases. Nervertheless, there was no explanation for the etiology of 117 cases of fetal death. CONCLUSION: stillbirth has frequently been observed among the primigravidae (40.74%), in preterm period (59.79%), and in the antepartum period (86.31%). Among fetal death causes, the most frequent was a abruptio placentae (18.42%), and in 61.57% of the cases the fetal death could not be explained.
- ItemSomente MetadadadosPrediction of intrauterine death and severe preterm delivery in twin pregnancies discordant for major fetal abnormality(Elsevier B.V., 2014-04-01) Kang, Helenice J.; Liao, Adolfo W.; Brizot, Maria L.; Francisco, Rossana P. V.; Krebs, Vera L. J.; Zugaib, Marcelo [UNIFESP]; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)Objective: To investigate predictors of spontaneous fetal death and preterm delivery in twin pregnancies with one fetus affected by a major structural malformation.Study design: Retrospective study (1999-2012) conducted at a tertiary teaching hospital involving 51 twin pregnancies (dichorionic = 31, monochorionic diamniotic = 15, monochorionic monoamniotic = 4, not established = 1) with a major fetal abnormality, enrolled before 26 weeks and managed expectantly. Primary outcomes: spontaneous fetal death, and/or delivery before 32 weeks. Prediction was examined with stepwise logistic regression analysis, and independent variables included: maternal age, gestational age at diagnosis, chorionicity, fetal gender, number and type of fetal abnormalities. Significance level was set at 0.15.Results: Fetal abnormalities were diagnosed at a mean gestation of 21.5 3.7 weeks: cardiac abnormalities were observed in 31.4% of abnormal fetuses, abdominal wall defects in 29.4%, central nervous system 21.5%, spine 17.6%, effusions 17.6%, noncardiac thoracic abnormalities 15.7%, genital and urinary system 13.7%, limbs and soft tissue 3.9%, intestinal 1.9% and facial defects 1.9%. Fetal death occurred in 15 (29.4%) abnormal fetuses and was significantly correlated with the number of fetal malformations (p = 0.02, OR = 2.54, 95% CI = 1.14-5.62), presence of effusion/hydrops (p = 0.06, OR = 4.7, 95% CI = 0.95-24) and monochorionic placenta (p = 0.11, OR= 2.8, 95% CI = 0.78-9.8). Normal co-twin fetal death occurred in four cases (7.8%) and was related to monochorionic pregnancies (p = 0.14, OR = 5.8, 95% CI = 0.56-61). Delivery before 32 weeks was observed in 14 (27.5%) pregnancies and was related to presence of effusion/ hydrops (p = 0.04, OR = 5.5, 95% CI = 1.07-28).Conclusion: Spontaneous fetal death and/or delivery before 32 weeks in twin pregnancies with one fetus affected by a major structural malformation are related to the number of abnormalities diagnosed and presence of fetal effusion or hydrops. 2014 Elsevier Ireland Ltd. All rights reserved.
- ItemAcesso aberto (Open Access)Teratoma congênito de orofaringe: relato de caso(Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, 2005-02-01) Chaves, Yuri Seguchi [UNIFESP]; Sousa, Jânio Serafim de [UNIFESP]; Feldner Junior, Paulo Cezar [UNIFESP]; Cruz, Reisson Serafim [UNIFESP]; Sartori, Marair Gracio Ferreira [UNIFESP]; Girão, Manoel João Batista Castello [UNIFESP]; Chaves, Hiromi Seguchi [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Oropharyngeal teratoma is the most rare type of teratoma, with only 2% of fetal teratomas. The diagnosis must be established as early as possible, preferably during the prenatal period. The prognosis will depend on the size and location of the lesion, growth rate of the lesion, degree of intracranial spread, its resectability, and immediate care at birth by a multisciplinary team. We report aparticular case of congenital oropharyngeal teratoma (epignathus). The diagnosis was made during the prenatal period by ultrasound, and the fetus evolved to intrauterine death at the 29th week. The anatomopathological examination revealed a female fetus, compatible with 27-28 weeks, oropharyngeal teratoma and congenital malformations.