Navegando por Palavras-chave "Diagnosis, differential"

Agora exibindo 1 - 12 de 12
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    Anemia in inflammatory bowel disease: prevalence, differential diagnosis and association with clinical and laboratory variables
    (Associação Paulista de Medicina - APM, 2014-04-14) Alves, Rodrigo Andrade; Miszputen, Sender Jankiel; Figueiredo, Maria Stella [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    CONTEXT AND OBJECTIVES:Anemia is the most frequent extraintestinal complication of inflammatory bowel disease. This study aimed to: 1) determine the prevalence of anemia among patients with inflammatory bowel disease; 2) investigate whether routine laboratory markers are useful for diagnosing anemia; and 3) evaluate whether any association exists between anemia and clinical/laboratory variables.DESIGN AND SETTING:Cross-sectional at a federal university.METHODS:44 outpatients with Crohn's disease and 55 with ulcerative colitis were evaluated. Clinical variables (disease activity index, location of disease and pharmacological treatment) and laboratory variables (blood count, iron laboratory, vitamin B12 and folic acid) were investigated.RESULTS:Anemia and/or iron laboratory disorders were present in 75% of the patients with Crohn's disease and in 78.2% with ulcerative colitis. Anemia was observed in 20.5% of the patients with Crohn's disease and in 23.6% with ulcerative colitis. Iron-deficiency anemia was highly prevalent in patients with Crohn's disease (69.6%) and ulcerative colitis (76.7%). Anemia of chronic disease in combination with iron deficiency anemia was present in 3% of the patients with Crohn's disease and in 7% of the patients with ulcerative colitis. There was no association between anemia and disease location. In ulcerative colitis, anemia was associated with the disease activity index.CONCLUSIONS:Most patients present iron laboratory disorders, with or without anemia, mainly due to iron deficiency. The differential diagnosis between the two most prevalent types of anemia was made based on clinical data and routine laboratory tests. In ulcerative colitis, anemia was associated with the disease activity index.
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    Apresentação atípica de degeneração marginal pelúcida: relato de caso
    (Conselho Brasileiro de Oftalmologia, 2005-12-01) Santos, Frederico Xavier Dos; Mocelin, Sheila; Machado, Renato; Santos, Fernando Henrique Xavier Dos; Sousa, Luciene Barbosa De [UNIFESP]; Hospital Oftalmológico de Sorocaba; Hospital Oftalmológico de Sorocaba Setor de Córnea; Hospital Oftalmológico de Sorocaba Setor de Córnea e Doenças Externas; Pontifícia Universidade Católica de Sorocaba; Universidade Federal de São Paulo (UNIFESP)
    The authors report an unusual clinical presentation of pellucid marginal degeneration with 360º peripheral corneal thinning diagnosed in a younger male patient. We discuss the findings of topographic maps, ultrasound pachymetry and the proposed treatment.
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    Canaliculite: relato de caso e conduta
    (Sociedade Brasileira de Oftalmologia, 2011-12-01) Lorena, Silvia Helena Tavares [UNIFESP]; Silva, João Amaro Ferrari [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    The canaliculitis is a rare infection and chronicle lachrymal pathology, whose commoner etiology is Actinomyces israelli ( bacteria anaeroby positive gram). This pathology does not present cure espontany The diagnosis differential with is done: Recurring chronic conjunctivitis, blefarity and hordeoly. The definitive treatment is the surgical (canaliculotomy)), being accomplished under location anesthetizes.
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    Glaucoma de pressão normal
    (Conselho Brasileiro de Oftalmologia, 2005-08-01) Tavares, Ivan Maynart [UNIFESP]; Mello, Paulo Augusto de Arruda [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); University of California Hamilton Glaucoma Center Department of Ophthalmology; MEC CAPES
    Normal tension glaucoma is an optic neuropathy in which the retinal nerve fiber layer thickness is reduced, the optic nerve is pathologically excavated, and the visual field is disturbed, although intraocular pressure is classified as normal. Patients with normal tension glaucoma are a heterogeneous group in which many systemic pathologic conditions may be present, and presenting ocular clinical signs that are difficult to be identified in the early stages of the disease. Treatment is more challenging than in hypertensive glaucomas. The authors sought to review the pathophysiology and differential diagnosis of this condition assessing vascular, rheumatic, neurological and genetic aspects that should be studied, as well as its treatment. The sources of references are PubMed (MEDLINE), LILACS and Cochrane Library (CENTRAL) databases.
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    Granuloma faciale: a rare disease from a dermoscopy perspective
    (Sociedade Brasileira de Dermatologia, 2013-12-01) Teixeira, Danilo Augusto; Estrozi, Bruna; Ianhez, Mayra; Federal University of Goiás Department of Dermatology; Pathologist at the Pathology Consulting Service - Botucatu (SP); Universidade Federal de São Paulo (UNIFESP); Federal University of Goiás
    The granuloma faciale is a rare and benign skin disease of unknown etiology, characterized by chronic leukocitoclastic vasculitis. It is characterized by skin lesions predominantly facial whose course is chronic and slowly progressive. The diagnosis is based on clinical features, histopathology and, more recently, in dermoscopy. We describe the case of a male patient, 40 years old, with a sarcoid lesion on the malar site, whose histopathological examination revealed a mixed inflammatory infiltrate with presence of Grenz zone. Dermoscopy revealed a pink background with white striations. The definitive diagnosis is made by histopathologic evaluation, and dermatoscopy can be helpful. It is known to be resistant to therapy, oral medications, intralesional and surgical procedures are options.
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    Melanocitoma do nervo óptico
    (Sociedade Brasileira de Oftalmologia, 2008-12-01) Gouveia, Enéias Bezerra; Morales, Maira Saad De Ávila [UNIFESP]; Centro Médico Avimed; Universidade Federal de São Paulo (UNIFESP)
    Melanocytoma of the optic disc is a well known variant of melanocytic nevus that usually occurs as a deeply pigmented lesion on the head of the optic disc. Historically, this tumor has often been confused with malignant melanoma. Histopathologically, it is composed of deeply pigmented round oval cells with abundant cytoplasm and small, round, bland nuclei. Melanocytomas is a benign, stationary tumors, with almost no propensity to undergo malignant transformation. Most cases that occur on the optic disc are visually asymptomatic, but they can cause an afferent pupillary and visual field defects. Importantly, it can exhibit malignant transformation into melanoma in 1 to 2% of the cases. The affected patients should have periodic follow up.
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    Meningoencephalitis associated with Mycoplasma pneumoniae
    (Instituto Israelita de Ensino e Pesquisa Albert Einstein, 2012-03-01) Lalibera, Isabella Batista de; Silveira, Guilherme de Abreu; Toma, Ricardo Katsuya [UNIFESP]; Kuo, Jack Yung; Troster, Eduardo Juan; Universidade de São Paulo (USP); Hospital Israelita Albert Einstein; Universidade Federal de São Paulo (UNIFESP); Hospital Israelita Albert Einstein Pediatric Department
    We report a case of a child with meningoencephalitis of atypical etiology. The patient developed the disease after an infection in the upper airways with unfavorable evolution. The clinical recovery was only possible after the administration of adequate antibiotic therapy for the etiological agent. This case report describes a child with meningoencephalitis of atypical etiology. The patient developed the disease after an infection in the superior airways with negative evolution. The clinical recovery was possible only after the introduction of adequate antibiotic therapy for the etiological agent.
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    Pseudotoxocaríase: relato de caso
    (Conselho Brasileiro de Oftalmologia, 2006-02-01) Zajdenweber, Moysés Eduardo [UNIFESP]; Moraes, Remo Turchetti; Brasil, Oswaldo Moura; Universidade Federal de São Paulo (UNIFESP); Universidade Federal do Rio de Janeiro
    The Authors describe a case where the initial diagnosis, clinical and laboratorial, was compatible with ocular toxocariasis. Therefore the follow-up added to a histopathologic examination disclosed a different diagnosis, proving the importance of the histopathologic examination, mainly in presumable diagnostics.
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    Sarcoma granulocítico em órbita: relato de caso
    (Conselho Brasileiro de Oftalmologia, 2005-08-01) Fonseca Junior, Nilson Lopes Da [UNIFESP]; Paves, Luis [UNIFESP]; Nakanami, Deise Mitsuko [UNIFESP]; Seixas, Maria Teresa [UNIFESP]; Manso, Paulo Góis [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Orbital granulocytic sarcoma is a localized tumor consisting of malignant cells of myeloid origin. This tumor may present in association with acute myelogenous leukemia. Granulocytic sarcoma may be found in a variety of locations throughout the body including the orbit and typically affects children and young adults. There is a slight male predominance in these cases. This is an uncommon case report of a 33-year-old Latin-American woman who was admitted to the Hospital for rapidly progressive orbital proptosis. There was no systemic manifestation of leukemia. The occurrence of orbital granulocytic sarcoma before the development of systemic leukemia in children and young adults is not uncommon and these cases frequently develop hematological evidence within 2 months after initial orbital disease. In this case report, there was no systemic manifestation of leukemia in the last 30 months, even in the presence of orbital tumors. Granulocytic sarcoma is most frequently confused with malignant lymphoma, rhabdomyosarcoma and neuroblastoma. The differential diagnosis of these cases can be challenging, particularly when there is no evidence of systemic leukemia, when imaging features are not sufficiently specific to distinguish granulocytic neoplasms from other tumors. To establish the diagnosis often a biopsy is required. The treatment in such cases (orbital granulocytic sarcoma) is not standardized. Orbital granulocytic sarcoma may be suspected in cases of orbital tumors even in the absence of systemic manifestations of leukemia at any age.
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    Transcranial sonography in Parkinson's disease
    (Instituto Israelita de Ensino e Pesquisa Albert Einstein, 2012-06-01) Bor-seng-shu, Edson; Pedroso, José Luiz [UNIFESP]; Andrade, Daniel Ciampi De; Barsottini, Orlando Graziani Povoas [UNIFESP]; Andrade, Luiz Augusto Franco de [UNIFESP]; Barbosa, Egberto Reis; Teixeira, Manoel Jacobsen; Universidade de São Paulo (USP); Hospital Israelita Albert Einstein; Universidade Federal de São Paulo (UNIFESP); Hospital Israelita Albert Einstein Instituto do Cérebro
    Transcranial sonography has become a useful tool in the differential diagnosis of parkinsonian syndromes. This is a non-invasive, low cost procedure. The main finding on transcranial sonography in patients with idiopathic Parkinson's disease is an increased echogenicity of the mesencephalic substantia nigra region. This hyperechogenicity is present in more than 90% of cases, and reflects a dysfunction in the dopaminergic nigrostriatal pathway. This study discussed how the hyperechogenicity of the substantia nigra may facilitate the differential diagnosis of parkinsonian syndromes.
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    Use of CD25 as an immunohistochemical marker for acquired ocular toxoplasmosis
    (Conselho Brasileiro de Oftalmologia, 2010-10-01) Miyamoto, Cristina [UNIFESP]; Belfort, Rubens Neto [UNIFESP]; Cesare, Sebastian Di; Belfort, Rubens Junior [UNIFESP]; Burnier Júnior, Miguel Noel Nascente [UNIFESP]; McGill University Witelson Ocular Pathology Laboratory; Universidade Federal de São Paulo (UNIFESP)
    PURPOSE: Toxoplasmosis is the most common cause of posterior infectious uveitis worldwide. It is often impossible to determine its congenital or acquired nature. Interleukin-2 (IL-2) in peripheral blood has been described as a possible marker for acquired toxoplasmosis. The purpose of this study is to evaluate the histopathological characteristics of ocular toxoplasmosis cases using CD25 as a marker for the expression of interleukin-2. METHODS: Ten formalin-fixed, paraffin-embedded enucleated globes from ten immunocompetent patients with clinical diagnosis of toxoplasmosis were evaluated. Four patients had the acquired form of ocular toxoplasmosis (positive IgM) while six were IgM negative and IgG positive for toxoplasmosis. Histopathological slides were reviewed for the extension of the retinal necrosis, number of toxo cysts, the granulomatous inflammatory reaction, the presence of T and B cells within the choroid and the IL-2 expression. Immunohistochemistry using monoclonal antibodies was performed to observe the expression of CD4, CD8, CD20, CD25, and CD68. RESULTS: The histopathological evaluation disclosed no differences between acquired and the other ocular toxoplasmosis cases regarding the characteristics studied. However, CD25 showed a higher expression of IL-2 on the 4 acquired cases of ocular toxoplasmosis compared to the remainders. CONCLUSIONS: To the best of our knowledge, this is the first report showing that the use of CD25 as a marker for interleukin-2 could differentiate acquired ocular toxoplasmosis.
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    Validity of Autism Behavior Checklist (ABC): preliminary study
    (Associação Brasileira de Psiquiatria - ABP, 2005-12-01) Marteleto, Márcia Regina Fumagalli [UNIFESP]; Pedromônico, Márcia Regina Marcondes [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    OBJECTIVE: To examine the concurrent and criterion validity of the Autism Behavior Checklist (ABC). METHODS: Three groups, comprising 38 mothers of children previously diagnosed with autism (DSM IV-TR, 2002), 43 mothers of children with language disorders other than autism, and 52 mothers of children who had no linguistic or behavioral complaints, were interviewed. In order to minimize the effect of maternal level of education, the questionnaire was completed by the researcher. To determine the concurrent validation, ANOVA and discriminant analysis were used. The ROC curve was used to establish the cutoff score of the sample and to examine the criterion validity. RESULTS: The mean total score was significantly higher in the group of mothers of autistic children than in the other groups. The ABC correctly identified 81.6% of the autistic children. The ROC curve cutoff score was 49, and the sensitivity was 92.1%, higher than the 57.89% found when a cutoff score of 68 was used. The specificity was 92.6%, similar to the 94.73% obtained with a cutoff score of 68. CONCLUSIONS: The ABC shows promise as an instrument for identifying children with autistic disorders, both in clinical and educational contexts, especially when a cutoff score of 49 is used.