Navegando por Palavras-chave "Coccidioidomycosis"
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- ItemSomente MetadadadosAntigens of Coccidioides posadasii as an Important Tool for the Immunodiagnosis of Coccidioidomycosis(Springer, 2013-02-01) Cordeiro, Rossana de Aguiar; Nobre Patoilo, Kharla Rabelo; Praciano, Silviane Bandeira; Astete Medrano, Delia Jessica; Farias Marques, Francisca Jakelyne de; Soares Martins, Liline Maria; Eulalio, Kelsen Dantas; Deus Filho, Antonio de; Salmito Cavalvanti, Maria do Amparo; Bezerra Fechine, Maria Auxiliadora; Nogueira Brilhante, Raimunda Samia; Camargo, Zoilo Pires de [UNIFESP]; Gadelha Rocha, Marcos Fabio; Costa Sidrim, Jose Julio; Univ Fed Ceara; Univ Fed Piaui; Inst Doencas Tropicais Natan Portella; Univ Integracao Int Lusofonia Afrobrasileira; Universidade Federal de São Paulo (UNIFESP); Univ Estadual CearaSerologic diagnosis has been presented as a safe alternative for coccidioidomycosis. However, commercial kits based on coccidioidal antibodies available in the USA are considered too expensive for laboratories outside that country. in this study, we describe the preparation of antigens for detection of human coccidioidal antibodies by the immunodiffusion test (ID) and enzyme immunoassay (EIA). Antigens were tested against serum samples from patients with coccidioidomycosis, histoplasmosis and paracoccidioidomycosis, as well as healthy individuals. the highest reactivity in the ID tests was seen in the F0-90 antigen. in the EIAs, the best results were obtained with the F60-90 antigen. None of the serum samples from healthy individuals were recognized by any of the antigen extracts tested by ID or EIA. in conclusion, the F0-90 and F60-90 antigens have the potential to be commercially employed in presumptive diagnosis of coccidioidomycosis by ID or EIA, respectively. the tests could improve serological diagnosis of coccidioidomycosis in South America.
- ItemAcesso aberto (Open Access)Coccidioidomicose pulmonar em caçador de tatus(Sociedade Brasileira de Pneumologia e Tisiologia, 2001-09-01) Costa, FabrÍcio AndrÉ Martins Da; Reis, Ricardo Coelho; Benevides, FÁbio; TomÉ, Geraldo De Sousa; Holanda, Marcelo AlcÂntara [UNIFESP]; Hospital de Messejana Serviço de Pneumologia; Universidade Federal do Ceará Departamento de Patologia e Medicina Legal; Universidade Federal de São Paulo (UNIFESP)Coccidioidomycosis is a disease caused by inhalation of arthrospores of the fungus Coccidioides immitis. It has been recognized as a clinical entity since 1892. It is related to activities that involves dust exposure. It is found in many regions of the western hemisphere with dry and alkaline soil. In Brazil it has been described almost exclusively in the Northeast region where drought periods may favor its growth in its soil. We report a case of fatal coccidioidomycosis, in an immunocompetent host, associated to the activity of armadillo hunting (Dasypus novemcynctus) in a rural area of Ceará state.
- ItemSomente MetadadadosCoccidioidomycosis and Histoplasmosis in Equines: An Overview to Support the Accurate Diagnosis(Elsevier Science Inc, 2016) Brilhante, Raimunda Samia Nogueira; Bittencourt, Paula Vago; Lima, Rita Amanda Chaves; Castelo-Branco, Debora; Oliveira, Jonathas Sales; Pinheiro, Adriana; Cordeiro, Rossana; Camargo, Zoilo Pires [UNIFESP]; Sidrim, Jose Julio Costa; Rocha, Marcos Fabio GadelhaFungal infections of the respiratory tract of horses are not as frequent as those of bacterial and viral origin, often leading to worsening of clinical conditions due to misdiagnosis and incorrect treatment. Coccidioidomycosis and histoplasmosis are systemic mycoses caused by the dimorphic fungi Coccidioides spp. and Histoplasma capsulatum, respectively, which affect humans and a variety of other animals, including equines. These systemic mycoses of chronic and progressive nature can exhibit clinical manifestations similar to other microbial infections. Thus, this article broadly discusses the epidemiology, etiology, virulence, pathogenesis, clinical presentation, treatment, and diagnostic strategies of coccidioidomycosis and histoplasmosis, to support accurate diagnosis. (C) 2016 Elsevier Inc. All rights reserved.
- ItemSomente MetadadadosSerologic Detection of Coccidioidomycosis Antibodies in Northeast Brazil(Springer, 2009-04-01) Cordeiro, Rossana de Aguiar; Bezerra Fechine, Maria Auxiliadora; Nogueira Brilhante, Raimunda Samia; Gadelha Rocha, Marcos Fabio; Freire da Costa, Ana Karoline; Tiemi Dias Nagao, Maria Aparecida; Camargo, Zoilo Pires de [UNIFESP]; Costa Sidrim, Jose Julio; Univ Fed Ceara; Univ Estadual Ceara; Universidade Federal de São Paulo (UNIFESP)Coccidioidomycosis is a systemic infection caused by Coccidioides spp. the disease is endemic in Brazil but its incidence is underreported as it is not a notifiable disease. This article presents the results of a serologic survey carried out with 229 volunteers in northeast Brazil by the immunodiffusion (ID) test with commercial Coccidioides spp. antigens. the commercial ID test detected 15 individuals without clinical diagnosis of the disease and two individuals in treatment for coccidioidomycosis. Regarding the epidemiological data, most of the positive individuals were male, between 18 and 65 years of age and were engaged in armadillo hunting. Three women who had never participated in armadillo hunts also displayed positive results for coccidioidal antibodies. Besides armadillo hunts, exposure to environmental dust in endemic areas may account for the serologic response detected in the study. the data from this study suggest the importance of performing epidemiological surveys for coccidioidomycosis in order to understand the prevalence of this disease in Brazil.
- ItemSomente MetadadadosTwelve years of coccidioidomycosis in Ceara State, Northeast Brazil: epidemiologic and diagnostic aspects(Elsevier B.V., 2010-01-01) Cordeiro, Rossana de Aguiar; Nogueira Brilhante, Raimunda Samia; Gadelha Rocha, Marcos Fabio; Bandeira, Silviane Praciano; Bezerra Fechine, Maria Auxiliadora; Camargo, Zoilo Pires de [UNIFESP]; Costa Sidrim, Jose Julio; Univ Estadual Ceara; Univ Fed Ceara; Universidade Federal de São Paulo (UNIFESP)Coccidioidomycosis is an endemic infection in the Americas caused by the dimorphic fungi Coccidioides immitis and Coccidioides posadasii. Although the disease occurs in Brazil in sporadic form, little information about these cases is available. in this study, we summarize the most important clinical, epidemiologic, and diagnostic features of coccidioidomycosis in Ceara State (Northeast Brazil) during the past 12 years. in this period, 19 cases of coccidioidomycosis were diagnosed. All the patients were young males and came from semiarid areas of the state. the majority of cases were associated to armadillo hunting, and pulmonary disease was the most common clinical presentation. in our laboratory, coccidioidomycosis was confirmed by culture, serology, and polymerase chain reaction tests, which together were very suitable for the diagnosis of this disease. Based on our local experience, we believe many cases of this disease are misdiagnosed or not diagnosed in our region. Therefore, some strategies for improvement of diagnosis should be encouraged by local authorities. (C) 2010 Elsevier Inc. All rights reserved.