Navegando por Palavras-chave "Case-control studies"
Agora exibindo 1 - 6 de 6
Resultados por página
Opções de Ordenação
- ItemAcesso aberto (Open Access)Amputações de extremidades inferiores por diabetes mellitus: estudo caso-controle(Faculdade de Saúde Pública da Universidade de São Paulo, 2004-06-01) Gamba, Mônica Antar [UNIFESP]; Gotlieb, Sabina Léa Davidson; Bergamaschi, Denise Pimentel; Vianna, Lucila Amaral Carneiro [UNIFESP]; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP)OBJECTIVE: Lower extremity amputation is an increasing problem among diabetic patients and an important public health problem. The study purpose was to identify factors associated with lower extremity amputation. METHODS: A matched case-control study was carried out among diabetic patients. Cases were selected in public health programs of the city of São Paulo, Brazil. One hundred and seventeen cases of diabetics with lower extremity amputation were compared to 234 controls of diabetics without amputation, matched by sex, age, and duration of disease. Sociodemographic variables, life habits (smoking and alcohol drinking), clinical aspects, and health education in diabetes were included. Univariate analyses and conditional logistic regression method were applied to data. RESULTS: Data showed evidence of association for: smoking, last glucose test >200 mg/dl, presence of peripheral somatic neuropathy and vibratory perception (tuning fork 128 Hz), and peripheral vascular disease. Diabetes treatment and attending nursing appointments for diabetes education were important factors for preventing lower extremity amputation in diabetic patients. CONCLUSIONS: The knowledge of determinants and intervening factors for this condition will lead to cost reduction and better quality of care delivered in public health services.
- ItemAcesso aberto (Open Access)Aspectos psicológicos das crianças com glaucoma do desenvolvimento(Conselho Brasileiro de Oftalmologia, 2004-12-01) Ferracina, Carla [UNIFESP]; Rodrigues, Adriana Maria [UNIFESP]; Belfort, Ricardo [UNIFESP]; Mello, Paulo Augusto de Arruda [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)PURPOSE: To evaluate the following psychological aspects of children with developmental glaucoma: immaturity, anxiety, dependence and sociability. METHODS: Fifteen children with developmental glaucoma from the Congenital Glaucoma department and fifteen children without any visual problem were evaluated through the projective technique of free drawing. RESULTS: In the group of children with glaucoma, 66.6% were immature, 86.6% were anxious, 73.3% were dependent and 80% had difficulties in sociability. In the control group, 46.6% were immature, 40% were anxious, 40% were dependent and 33.3% had difficulties in sociability. CONCLUSION: Children with glaucoma were considered more immature, more anxious, more dependent and less sociable than children without any visual problem.
- ItemAcesso aberto (Open Access)Dietary patterns and risk of oral cancer: a case-control study in São Paulo, Brazil(Faculdade de Saúde Pública da Universidade de São Paulo, 2007-02-01) Marchioni, Dirce Maria Lobo; Fisberg, Regina Mara; Góis Filho, José Francisco de; Kowalski, Luiz Paulo [UNIFESP]; Carvalho, Marcos Brasilino de; Abrahão, Márcio [UNIFESP]; Latorre, Maria Do Rosário Dias de Oliveira; Eluf-Neto, José; Wünsch Filho, Victor; Universidade de São Paulo (USP); Instituto do Câncer Arnaldo Vieira de Carvalho Departamento de Cabeça e Pescoço; Hospital do Câncer A.C.Camargo Departamento de Cabeça, Pescoço e Otorrinolaringologia; Hospital Heliópolis Departamento de Cabeça e Pescoço; Universidade Federal de São Paulo (UNIFESP)OBJECTIVE: To analyze the association between dietary patterns and oral cancer. METHODS: The study, part of a Latin American multicenter hospital-based case-control study, was conducted in São Paulo, Southeastern Brazil, between November 1998 and March 2002 and included 366 incident cases of oral cancer and 469 controls, frequency-matched with cases by sex and age. Dietary data were collected using a food frequency questionnaire. The risk associated with the intake of food groups defined a posteriori, through factor analysis (called factors), was assessed. The first factor, labeled prudent, was characterized by the intake of vegetables, fruit, cheese, and poultry. The second factor, traditional, consisted of the intake of rice, pasta, pulses, and meat. The third factor, snacks, was characterized as the intake of bread, butter, salami, cheese, cakes, and desserts. The fourth, monotonous, was inversely associated with the intake of fruit, vegetables and most other food items. Factor scores for each component retained were calculated for cases and controls. After categorization of factor scores into tertiles according to the distribution of controls, odds ratios and 95% confidence intervals were calculated using unconditional multiple logistic regression. RESULTS: Traditional factor showed an inverse association with cancer (OR=0.51; 95% CI: 0.32; 0.81, p-value for trend 0.14), whereas monotonous was positively associated with the outcome (OR=1.78; 95% CI: 1.78; 2.85, p-value for trend <0.001). CONCLUSIONS: The study data suggest that the traditional Brazilian diet, consisting of rice and beans plus moderate amounts of meat, may confer protection against oral cancer, independently of any other risk factors such as alcohol intake and smoking.
- ItemAcesso aberto (Open Access)Fatores de risco para o prolapso genital em uma população brasileira(Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, 2009-01-01) Rodrigues, Andrea Moura [UNIFESP]; Oliveira, Letícia Maria de [UNIFESP]; Martins, Karina de Falco [UNIFESP]; Roy, Carlos Antônio Del [UNIFESP]; Sartori, Marair Gracio Ferreira [UNIFESP]; Girão, Manoel João Batista Castello [UNIFESP]; Castro, Rodrigo de Aquino [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)PURPOSE: to evaluate risk factors for the development of genital prolapse in the Brazilian population. METHODS: case-control study involving 316 patients submitted to prolapse staging, according to the pelvic organ prolapse quantification system. The patients were divided into two groups: in the Case Group there were 107 patients with prolapse at stage III or IV, and in the Control Group, 209 women at stage 0 or I. In the anamnesis, the selected women have been questioned about the presence of possible risk factors for genital prolapse, such as: age, menopause age, parturition, delivery type (vaginal, caesarean section or forceps), occurrence of fetal macrosomia, family history of genital dystopia in first degree relatives, chronic cough and intestinal constipation. RESULTS: The variables that were different between the groups were: age, body mass index, parturition, number of vaginal, caesarean section or forceps deliveries, newborn weight and positive family history for prolapse. Race, menopause age, chronic cough and intestinal constipation did not present differences between the groups. After logistic regression, only three variables have been shown to be independent risk factors: presence of at least one vaginal delivery, fetal macrosomia and positive family history for dystopia. Cesarean section was shown to be a protective factor. CONCLUSION: in the Brazilian population, the independent risk factor for genital prolapse were: personal antecedent of at least one vaginal delivery, fetal macrosomia and family history of dystopia.
- ItemAcesso aberto (Open Access)Fatores maternos e neonatais associados a prematuridade em maternidades públicas do acre(Universidade Federal de São Paulo (UNIFESP), 2018-06-28) Santos, Clisangela Lago [UNIFESP]; Schirmer, Janine [UNIFESP]; Dotto, Leila Maria Geromel; http://lattes.cnpq.br/3721636964139813; http://lattes.cnpq.br/1379096849417363; Universidade Federal de São Paulo (UNIFESP)Objective: To analyze the maternal and neonatal factors associated with prematurity in public maternity hospitals in Acre. Methods: Casecontrol studies we selected 383 preterm births (cases) and 396 fullterm births (controls) of mothers who delivered at the highrisk reference maternity hospitals located in Rio Branco and Cruzeiro do Sul, Acre, between October, 2016 and July, 2017. Mothers were interviewed using a validated instrument. Additionally, information was collected from the hospital records regarding the newborns and their mothers, participating of the research. Newborns with divergences between reported Gestational Age (GA) registries that interfered with preterm/term classification were excluded. The variables were divided into five blocks and analyzed according to the conceptual hierarchical model. Descriptive and inferential analyzes were performed using: chisquare test, p value ≤0,20 for the inclusion of variables in the multiple logistic regression analysis between the blocks, and crude and adjusted Odds Ratio with the correspondent intervals of confidence, after established a new cut p value ≤0,05 for inclusion in the multiple regression logistic for hierarquical analysis. Results: 287 (75%) of the mothers had deliveries classified as spontaneous and 96 (25%) by medical indication (all by caesarean section) due to pregnancy complications. Births between 32 and 36 weeks accounted for 89% of all preterm births. Among the cases, 61.1% were classified as underweight while only 3.5% had this status in the control group. After block modeling, newborns born from premature mothers (p = 0.010), with low BMI (p = 0.003), with an interval between pregnancies < 12 months (p = 0.028), previos preterm birth (p<0.001) and maternal stress (p=0.003), maternal physical injury (p=0,045), with inadequate prenatal care type I (p = 0.020) and type II (p = 0.029), with gestation twin (p <0.001), altered volume of uterine fluid (p <0.001), preeclampsia/eclampsia (p <0.001), and hospitalization during pregnancy (p <0.001) had a greater chance of preterm birth. Maternal education level and occupation had a protective effect. Conclusion: Biological characteristics, maternal psychological and emotional conditions, insufficient prenatal care, gestation twin, complications such as bleeding, preeclampsia/eclampsia, and changes in uterine fluid volume were the main risk factors identified. Due to the multicausality of preterm birth, further research with primary data may contribute to the evaluation of the phenotypes of spontaneous and medically indicated preterm delivery in order to verify if there is a difference between the associated factors, seeking to contribute to the elucidation of the riddle of prematurity.
- ItemAcesso aberto (Open Access)A posição de amamentar determina o aparecimento do trauma mamilar?(Universidade de São Paulo, Escola de Enfermagem, 2009-06-01) Coca, Kelly Pereira [UNIFESP]; Gamba, Mônica Antar [UNIFESP]; Silva, Rebeca de Souza e [UNIFESP]; Abrão, Ana Cristina Freitas de Vilhena [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)The aim of the study was to identify the breast feeding position and holding variables related to nipple trauma. This case-control study assessed the onset of nipple trauma among women hospitalized at a University Hospital in the city of São Paulo, in 2004 and 2005. Subjects were puerperae diagnosed with unilateral or bilateral nipple trauma. Data analysis was performed using chi-square, Student's t, and odds ratio tests (CI= 95%) and correspondence analysis. Participants were 146 puerperal women and their newborns, being 73 cases and 73 controls. Statistically significant position and holding variables for causing lesions were the following: newborns with their necks bent/contorted, chin away from the breast and lip-related defect (turned inward). Trauma prevention at the beginning of breast feeding is crucial for continuing this practice. Following adequate positioning is decisive for establishing effective and prolonged breast feeding.