Navegando por Palavras-chave "Body composition"

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    Accelerometer-determined peak cadence and weight status in children from Sao Caetano do Sul, Brazil
    (Abrasco, 2017) de Moraes Ferrari, Gerson Luis [UNIFESP]; Araujo, Timoteo; Oliveira, Luis Carlos; Rodrigues Matsudo, Victor Keihan; Mire, Emily; Barreira, Tiago; Tudor-Locke, Catrine; Katzmarzyk, Peter T.
    The purpose of this study was to determine the relationship between peak cadence indicators and body mass index (BMI) and body fat percentage (BF%)-defined weight status in children. The sample comprised 485 Brazilian children. Minute-by-minute step data from accelerometry were rank ordered for each day to identify the peak 1-minute, 30-minute and 60-minute cadence values. Data were described by BMI-defined and bioelectrical impedance-determined BF% weight status. BMI-defined normal weight children had higher peak 1-minute (115.5 versus 110.6 and 106.6 steps/min), 30-minute (81.0 versus 77.5 and 74.0 steps/min) and 60-minute cadence (67.1 versus 63.4 and 60.7 steps/min) than overweight and obese children (p<.0001), respectively. Defined using %BF, normal weight children had higher peak 1-minute (114.5 versus 106.1 steps/min), 30-minute (80.4 versus 73.1 steps/min) and 60-minute cadence (66.5 versus 59.9 steps/min) than obese children (p<.0001). Similar relationships were observed in boys; however, only peak 1-minute cadence differed significantly across BMI and % BF-defined weight status categories in girls. Peak cadence indicators were negatively associated with BMI and BF% in these schoolchildren and significantly higher among normal weight compared to overweight or obese children.
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    Adolescentes jogadoras de handebol apresentam conteúdo mineral ósseo superior ao de adolescentes jogadoras de futebol: um estudo transversal
    (Universidade Federal de São Paulo, 2024-01-18) Fagundes, Ulysses [UNIFESP]; Lira, Claudio Andre Barbosa de; Andrade, Marilia dos Santos [UNIFESP]; http://lattes.cnpq.br/8618739762906389; http://lattes.cnpq.br/3289964716112944; http://lattes.cnpq.br/5352738309999132
    Introdução: A adolescência é o período de vida em que se obtém entre 40 e 60% da massa óssea, algo extremamente importante para prevenção de osteoporose na fase adulta. Entre os vários fatores que podem estimular esse ganho de massa óssea está a prática de atividade física. Entretanto, não está claro na literatura que tipo de atividade física é capaz de gerar maiores ganhos. Objetivo: Comparar o conteúdo mineral ósseo (CMO), a densidade mineral óssea (DMO) e a massa magra de adolescentes atletas (jogadoras de futebol e jogadoras de handebol) e um padrão de referência norte-americano com o intuito de verificar o efeito da modalidade esportiva praticada sobre a massa óssea e massa magra. Métodos: Este estudo transversal mediu o CMO, a DMO, a DMO total do corpo menos cabeça (TBLH) e a massa magra usando absorciometria de raios-X de dupla energia (DXA) em 115 jogadoras de handebol (15,5 ± 1,3 anos, 165,2 ± 5,6 cm e 61,9 ± 9,3 kg) e em 142 jogadoras de futebol (15,5 ± 1,5 anos, 163,7 ± 6,6 cm e 56,5 ± 7,7 kg). Além disso, 136 adolescentes mulheres formaram o grupo de valores padrão de referência norte-americano (15,1 ± 1,3 anos, 163,5 ± 5,8 cm e 67,2 ± 19,4 kg), cujos dados referentes à massa óssea foram extraídos do estudo “National Health and Nutrition Survey” (NHANES). Resultados: Observou-se que jogadoras de handebol, quando comparadas às futebolistas, apresentaram valores maiores de CMO em membros superiores (294,8±40,2 g e 270,7±45,7 g, p < 0,001), membros inferiores (1011,6±145,5 g e 967,7±144,3 g, p = 0,035), tronco (911,1±182,5 g e 841,6±163,7 g, p = 0,001), costelas (312,4±69,9 g e 272,9±58,0 g, p < 0,001), vértebras (245,1±46,8 g e 222,0±45,1 g, p < 0,001) e massa óssea total (2708,7±384,1 g e 2534,8±386,0 g, p < 0,001), respectivamente. Os valores do padrão de referência norte-americano para o CMO em membros inferiores (740,6±132,3 g, p < 0,001), tronco (539,7±98,6 g, p < 0,001), costelas (138,2±29,9 g, p < 0,001), pelve (238,9±54,6 g, p < 0,001), vértebras (152,8±26.4 g, p < 0,001) e massa óssea total (1987,5±311.3 g, p < 0,001) foram inferiores quando comparadas às adolescentes das duas modalidades esportivas. As jogadoras de handebol, quando comparadas às futebolistas, também apresentaram valores maiores de DMO em tronco (1,02±0,87 g/cm2 e 0,99±0,83 g/cm2 , p=0,017), costelas (0,77±0,06 g/cm2 e 0,74±0,05 g/cm2 , p<0,001) e vértebras (1,15±0,11 g/cm2 e 1,09±0,12 g/cm2 , p<0,001). As adolescentes atletas apresentaram DMO superior a apresentada pelo padrão de referência norte-americano para todas as medidas realizadas (membros superiores, inferiores, tronco, costelas, pelve, coluna e total) (p<0,005). Com relação à massa magra, não houve diferença entre os 3 grupos com relação à massa magra de membros superiores (p=0,112) e massa magra total (p=0,524). Porém, a massa magra de membros inferiores foi menor no grupo do ix padrão de referência norte-americano do que nos grupos de jogadoras de futebol e handebol (p=0,001). Conclusões: Meninas adolescentes que praticam handebol por pelo menos um ano apresentam CMO superior ao encontrado em adolescente praticantes de futebol. Além disso, as adolescentes atletas das duas modalidades apresentam CMO e DMO superiores ao padrão de referência norte-americano. Esses resultados podem ser usados por médicos, profissionais de saúde e educação física para justificar a escolha de uma modalidade esportiva específica para aumento de CMO e DMO em meninas adolescentes.
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    Análise da relação entre a taxa metabólica basal, a composição corporal e o sono em idosos antes e após o treinamento resistido
    (Universidade Federal de São Paulo (UNIFESP), 2009-06-24) Boscolo, Rita Aurélia [UNIFESP]; Mello, Marco Tulio de [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Durante o processo de envelhecimento ocorrem alterações neuroquímicas, morfológicas e funcionais, como a redução de algumas das características do sono, da quantidade da massa livre de gordura e da taxa metabólica basal. Estes fatores podem estar relacionados uma vez que a diminuição da taxa metabólica basal ocorre em conseqüência da diminuição da massa livre de gordura. O treinamento físico provavelmente pode minimizar tais efeitos e/ou trazer resultados positivos ao padrão do sono, assim como aos parâmetros da composição corporal e ao metabólico. O objetivo deste estudo foi avaliar os efeitos do treinamento resistido na taxa metabólica basal (TMB), na composição corporal e nos parâmetros do sono, verificando as suas possíveis relações em homens idosos. A amostra foi composta por 37 homens idosos com uma idade entre os 65 e os 75 anos, distribuídos aleatoriamente em dois grupos: o controle (GC) e o resistido (GR). O protocolo incluiu 72 sessões de treinamento resistido progressivo realizado três vezes semanais; e avaliações do metabolismo basal, da composição corporal, do sono (objetiva e subjetiva) e do consumo alimentar. Os resultados demonstraram que a força muscular aumentou em todos os grupos musculares no GR. Nas variáveis morfológicas, somente o GC aumentou a massa gorda e diminuiu a livre de gordura na avaliação final, enquanto que o GR manteve todas as variáveis da composição corporal. A TMB e o consumo energético diário não sofreram alterações em ambos os grupos ao longo das avaliações. Nas variáveis do sono, o GC aumentou o tempo total de sono, os microdespertares e o valor da escala de Pittsburgh, enquanto que o GR reduziu significativamente o percentual do estágio 1 do sono NREM. Houve associação de causa e efeito da massa livre de gordura (kg) e do estágio 1 sobre a TMB com o modelo final de regressão (TMB= 539,81 + 21,99 massa livre de gordura – 26,01 estágio 1), o que explica os 34% da variação da TMB. Em conclusão, os resultados sugeriram que o treinamento resistido, apesar de não alterar as relações entre a TMB, o sono e a composição corporal, foi efetivo para aumentar a força muscular, manter a massa livre de gordura e a TMB, e ainda melhorar a qualidade do sono em idosos saudáveis, refletindo numa qualidade de vida mais ativa para uma longevidade saudável.
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    Análise de taxa metabólica basal e composição corporal de idosos do sexo masculino antes e seis meses após exercícios de resistência
    (Sociedade Brasileira de Medicina do Exercício e do Esporte, 2005-02-01) Antunes, Hanna Karen Moreira [UNIFESP]; Santos, Ruth Ferreira [UNIFESP]; Boscolo, Rita Aurélia [UNIFESP]; Bueno, Orlando Francisco Amodeo [UNIFESP]; Mello, Marco Tulio de [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    The aim of this study was to compare basal metabolic rate and body composition before and after an endurance-type physical fitness program. The study involved 46 sedentary aging males, aged 60-75 (66.97 ± 4.80 years), who were randomly allocated to two groups: 1) control group, which was asked not to change their daily routine or join a regular physical fitness program; and 2) experimental group, who took part in an aerobic fitness program consisting of working on cycle ergometer three times a week (60 minutes) on alternate days for six months, at heart rate corresponding to ventilatory threshold 1 (VT-1) intensity. Subjects were submitted to measurement of body composition (DEXA); indirect calorimetry, blood analysis and ergospirometric testing. After the study period, the authors found a significant decrease in thyroid hormones as well as basal metabolism changes in both groups, but no changes in body composition. The experimental group, however, showed a significant increase in peak oxygen uptake and workload at VT-1 intensity. The data suggest that although an aerobic exercise program at VT-1 intensity is not enough to alter the basal metabolism and body composition of healthy seniors, it does lead to cardiovascular benefits.
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    Analysis of the body composition of Paralympic athletes: Comparison of two methods
    (Taylor & Francis Ltd, 2016) Lemos, Valdir de Aquino [UNIFESP]; Alves, Eduardo da Silva [UNIFESP]; Schwingel, Paulo Adriano; Rosa, João Paulo Pereira; Silva, Andressa da; Winckler, Ciro; Vital, Roberto; Almeida, Alexandre Aparecido de [UNIFESP]; Tufik, Sergio [UNIFESP]; Mello, Marco Tulio de; Universidade Federal de São Paulo (UNIFESP)
    Body composition is a physiological variable associated with physical activity and, in some cases, is related to athletic performance. Our objectives were to describe the body composition of participants in three distinct Paralympic sports and to compare the values of body density and estimated body fat obtained from the Paralympic athletes on the National Team by air-displacement plethysmography (ADP) and by the anthropometric method (skinfolds (SFs)). The sample consisted of 70 volunteers of both genders. The body composition of the volunteers was evaluated using the ADP in a Bod Pod((R)) and seven SFs. There were no significant differences between the values obtained by ADP and SF for body fat percentage (p=.58) and body density (p=.49). Analysis by Bland-Altman plots showed mean differences of 0.56 +/- 4.94 (-9.12-10.23) and -0.0017 +/- 0.0113 (-0.024-0.020) for body fat percentage and body density, respectively. In conclusion, body composition analyses of Paralympic athletes by the ADP and SF methods show similar results, and ADP should be used as the first option when available. When the use of ADP is not possible, estimating body density and fat percentage by SF is a viable alternative for Paralympic athletes when future comparisons will use the same analysis method.
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    Assessment of Body Composition and Sport Performance of Brazilian Paralympic Swim Team Athletes
    (Human Kinetics Publ Inc, 2016) Medeiros, Radamés Maciel Vítor [UNIFESP]; Alves, Eduardo da Silva [UNIFESP]; Lemos, Valdir de Aquino [UNIFESP]; Schwingel, Paulo Adriano; Silva, Andressa da; Vital, Roberto; Vieira, Alexandre S.; Barreto, Murilo M.; Rocha, Edilson Alves da; Tufik, Sergio [UNIFESP]; Mello, Marco Tulio de
    Context: Body-composition assessments of high-performance athletes are very important for identifying physical performance potential. Although the relationship between the kinanthropometric characteristics and performance abilities of Olympic swimmers is extremely important, this subject is not completely understood for Paralympic swimmers. Objective: To investigate the relationship between body composition and sport performance in Brazilian Paralympic swimmers 6 mo after training. Design: Experimental pre/posttest design. Setting: Research laboratory and field evaluations of swimming were conducted to verify the 50-m freestyle time of each athlete. Participants: 17 Brazilian Paralympic swim team athletes (12 men, 5 women). Main Outcome Measures: Body-composition assessments were performed using a BOD POD, and swimming performance was assessed using the 50-m freestyle, which was performed twice: before and after 6 mo of training. Results: Increased lean mass and significantly reduced relative fat mass and swimming time (P < .05) were observed 6 mo after training. Furthermore, a positive correlation between body-fat percentage and performance (r = .66, P < .05) was observed, but there was no significant correlation between body density and performance (r = -.14, P > .05). Conclusions: After a 6-mo training period, Paralympic swimmers presented reduced fat mass and increased lean body mass associated with performance, as measured by 50-m freestyle time. These data suggest that reduced fat-mass percentage was significantly correlated with improved swimming performance in Paralympic athletes.
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    Assessment of Nutritional Status and Eating Disorders in Female Adolescents With Fibromyalgia
    (Elsevier B.V., 2012-11-01) Silva, Simone Guerra L. da [UNIFESP]; Sarni, Roseli O. S. [UNIFESP]; Souza, Fabiola I. S. de [UNIFESP]; Molina, Juliana [UNIFESP]; Terreri, Maria Teresa R. A. [UNIFESP]; Hilário, Maria Odete Esteves [UNIFESP]; Len, Claudio Arnaldo [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Purpose: To assess eating disorders, nutritional status, body composition, and food intake in adolescents presenting with fibromyalgia.Methods: in a cross-sectional study, we evaluated the nutritional status (z score of body mass index [ZBMI]), waist circumference, body fat percentage by bioelectrical impedance analysis, symptoms of disordered eating, and possible eating disorders (Kids' Eating Disorders Survey [KEDS]) of 23 female adolescents with fibromyalgia and 23 matched healthy control subjects.Results: Median age for both groups was 15 years. in the fibromyalgia group, the median time for diagnosis was 13.5 months. We did not observe a statistically significant difference between the control and fibromyalgia groups in relation to ZBMI, fat mass percentage, food intake, and symptoms of disordered eating (KEDS). in the fibromyalgia group, there was a significant correlation between fat mass percentage and the total KEDS score (r = .587, p = .003); the same correlation was observed for ZBMI (r = .0778, p < .001).Conclusions: This study verified an absence of nutritional and eating disorders in adolescents recently diagnosed with fibromyalgia that, in addition to the correlation between adiposity indexes and KEDS total score, emphasizes the importance of nutritional and body composition assessment, allowing an early and adequate nutritional intervention. (C) 2012 Society for Adolescent Health and Medicine. All rights reserved.
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    Associação entre a perda de peso, a massa óssea, a composição corporal e o consumo alimentar de adolescentes obesos pós-púberes
    (Sociedade Brasileira de Endocrinologia e Metabologia, 2008-08-01) Santos, Luana C.; Cintra, Isa de Pádua [UNIFESP]; Fisberg, Mauro [UNIFESP]; Lazaretti-Castro, Marise [UNIFESP]; Martini, Lígia A.; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)
    OBJECTIVE: To verify the effects of weight loss on bone mass of obese adolescents submitted to a nutritional intervention based on a hypocaloric diet and nutritional advice over a nine-month-period. METHODS: Anthropometry, body composition, BMD and dietary intake were evaluated. RESULTS: Fifty-five adolescents, 78.2% females, within an average age of 16.6 (1.4) years old participated in the study. Sixteen participants who completed the study did not lose weight. The group that adhered to the nutritional intervention had a mean weight loss of 6.2 (4.6)% baseline. There was a significant increase in total BMD and bone mineral content (BMC) in those adolescents who did not lose weight, while increased BMC and bone area were verified in participants who lost weight, mainly when associated with body composition alterations while changing weight. CONCLUSION: The increment in bone mineral density, even throughout weight loss, has showed no negative effect on bone mass and has also emphasized the importance of nutritional improvement in total bone mass during adolescence.
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    Associação entre equilíbrio muscular de membros inferiores e economia de corrida em corredores bem treinados do sexo masculino
    (Universidade Federal de São Paulo (UNIFESP), 2017-11-30) Silva, Wallace de Almeida [UNIFESP]; Andrade, Marilia dos Santos [UNIFESP]; http://lattes.cnpq.br/8618739762906389; http://lattes.cnpq.br/2100193157528466; Universidade Federal de São Paulo (UNIFESP)
    Background: The aim of the present study was to verify if flexor and extensor muscles peak torque (PT), balance ratios of knee and hip muscles or body composition is associated with running economy (RE) evaluated in level or uphill running in well trained male runners. Methods: 24 male long distance runners (31.0±7.7 years old, 176.2±7.3 cm and 70.4±8.4 kg) participated in the study. Maximal oxygen uptake ( ̇O2máx), conventional and functional balance ratio, PT of hip and knee flexor and extensor muscles, total body mass, fat mass and fat free mass were evaluated. RE was evaluated through the variables: Oxygen cost (OC) and energy cost (EC). In two separated days, RE was evaluated at 11 and 14 km/h on level ground (1% level-grade) and in 10 and 12 km/h on uphill (3% level-grade). Isokinetic testing was performed at 60 and 180º/s for hip and at 60 and 240º/s for knee joint. Results: Functional balance ratio of the hip muscles presented a significant negative relationship (p<0.05) with EC at 12 km/h in uphill and at 14 km/h in level-grade running (r= -0.69 to -0.70, respectively), OC presented meaningful relationship with hip functional balance ratio only when evaluated at 14 km/h (r= -0.73). Conventional and functional balance ratio of knee joint presented no relevant correlations with EC and OC. EC and OC presented significant relationships with PT of knee and hip muscles, total body mass, fat mass and fat free mass (p<0.05). Conclusion: High hip functional balance ratio values are associated with better RE. On the other hand, high PT values, total body mass, fat mass or fat free mass values are associated with poor RE. Thus, eccentric strengthening of hip flexor muscles should be emphasized in training, aiming to increase the functional balance ratio in long distance male runners. However, muscle strength training shouldn´t aim to increase muscular hypertrofy, but should aim to improve neuromuscular recruitment, since the increase of total body mass and fat free mass are associated with poor RE.
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    Association between osteoporosis and rheumatoid arthritis in women: a cross-sectional study
    (Associação Paulista de Medicina - APM, 2009-07-01) Sarkis, Karin Sedó; Salvador, Mariana Barbieri; Pinheiro, Marcelo de Medeiros [UNIFESP]; Silva, Raissa Gomes [UNIFESP]; Zerbini, Cristiano Augusto de Freitas; Martini, Lígia Araújo; Universidade de São Paulo (USP); Universidade Federal de São Paulo (UNIFESP)
    CONTEXT AND OBJECTIVES: Osteoporosis has frequently been observed in patients with rheumatoid arthritis. The present study was undertaken in order to evaluate factors associated with osteoporosis among women with rheumatoid arthritis. DESIGN AND SETTING: Cross-sectional study, carried out in a public hospital in São Paulo. METHODS: The participants were 83 women with rheumatoid arthritis (53.7 ± 10.0 years old). Bone mineral density (BMD) and body composition were measured by dual energy X-ray absorptiometry. The patients were divided into three groups according to BMD: group 1, normal BMD (n = 24); group 2, osteopenia (n = 38); and group 3, osteoporosis (n = 21). Tests were performed to compare differences in means and correlations, with adjustments for age, duration of disease and cumulative corticosteroid. The relationships between clinical factors, physical activity score, dietary intake, body composition and biochemical parameters were analyzed using linear regression models. RESULTS: Mean calcium, vitamin D and omega-6 intakes were lower than the recommendations. Associations were found between BMD and age, disease duration, parathyroid hormone concentration and fat intake. The linear regression model showed that being older, with more years of disease and lower weight were negatively correlated with BMD [Total femur = 0.552 + 0.06 (weight) + 0.019 (total physical activity) - 0.05 (age) - 0.003 (disease duration); R² = 48.1; P < 0.001]. CONCLUSION: The present study indicates that nutritional factors and body composition are associated with bone mass in women with rheumatoid arthritis.
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    Avaliação antropométrica, padrão de morbidade, alterações metabólicas, composição corporal e ingestão de alimentos de crianças em processo de recuperação nutricional atendidas no centro de recuperação e educação nutricional(CREN)
    (Universidade Federal de São Paulo (UNIFESP), 2001) Vieira, Maria de Fátima Alves [UNIFESP]; Sawaya, Ana Lydia [UNIFESP]
    Este estudo teve como objetivo avaliar a recuperação nutricional (alterações metabólicas, composição corporal, padrão de morbidade e consumo alimentar) de crianças desnutridas atendidas pelo Centro de Recuperação e Educação Nutricional (CREN) durante o período de Setembro de 1995 a Julho de 1999. Foram avaliadas 106 crianças agrupadas em dois clusters de acordo com o estado nutricional no momento da internação, sendo 65 com desnutrição leve 41 com desnutrição moderada e/ou grave. O tempo médio de internação foi de 16,3 meses e a média de idade no ingresso foi de 23,7 meses. A média de peso ao nascer do grupo foi de 2.563g. Houve associação positiva e significante entre o tempo de tratamento e os ganhos de peso/idade e de estatura/idade para o conjunto das crianças. O ganho de estatura/idade foi significantemente maior entre os desnutridos graves e entre as crianças nascidas com baixo peso. Observou-se ganho de gordura corporal significativamente maior entre os desnutridos graves. Houve associação significante e negativa entre os níveis de cortisol salivar e os ganhos de estatura/idade e de peso/idade, O percentual de crianças com valores de glicemia abaixo da faixa de normalidade foi de 26 por cento e de insulinemia foi de 72 por cento. O consumo de calorias e proteínas por kg de peso corporal efetuado no CREN foi significantemente maior entre os desnutridos graves. Foram observados valores elevados de VLDL colesterol (l4 por cento) e de triglicerídeos (40 por cento), e reduzidos de HDL colesterol (76 por cento). Os resultados da análise multivariada mostraram que o déficit inicial de estatura/idade foi a principal variável associada com o ganho de estatura/idade durante o tratamento.
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    Avaliação da composição corporal em crianças e adolescentes com artrite idiopática juvenil
    (Universidade Federal de São Paulo (UNIFESP), 2010-05-26) Caetano, Michelle Cavalcante [UNIFESP]; Hilário, Maria Odete Esteves [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Objective: To evaluate the body composition (BC) in children and adolescents with juvenile idiopathic arthritis (JIA). Methods: Through a cross-sectional, retrospective and controlled study we assessed the BC of 63 children and adolescents with JIA, matched for age and gender with 53 healthy controls. The weight and height were used to calculate the body mass index, classified in z score (ZBMI). The BC was determined by dual-energy X-ray absorptiometry (LUNAR TM DPX-MD plus, DXA). The following parameters were calculated: fat mass index (FMI, fat mass/ height²), lean mass index (LMI, lean mass/height ²), appendicular fat mass index (IGE, appendicular fat mass/height²), appendicular lean mass index (IMME, appendicular lean mass/height²) and the relationship between appendicular/truncal fat (BPT). An FMI value over third quartile of the control group was considered inappropriate. Results: In the patients we observed a female prevalence (66.7%) and the most frequent subtype was polyarticular (50.8%). The median disease duration was 62.5 months and 84 months for boys and girls, respectively. Respectively, 52.4% and 61.9% of boys and girls were eutrofic according to ZBMI. The BC measured in girls, through DXA, showed significantly higher body fat percentual compared with controls (4.83 kg/m2 vs 2.23 kg/m2; p<0.001), different from the one observed in the boys (2.2 kg/m2 vs 2.83 kg/m2; p=0,47). BPT was significantly more elevated in JIA group than in controls in both gender (p≤0. 001). There was no significant association between FMI and the variables related to the disease and treatment. BMI showed lower discriminatory power in identifying adiposity excess in girls than in boys (likelihood ratio =+ 80%). Conclusion: Girls with JIA had a higher FMI compared with the control group, what could be related to a higher risk for cardiovascular complications. The ZBMI in girls with JIA, had a weak correlation with FMI.
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    Avaliação da composição corporal, função cognitiva e resposta à cirurgia bariátrica em pacientes com histórico de esteatose hepática
    (Universidade Federal de São Paulo, 2023-11-22) Silva, Vitória Fernandes [UNIFESP]; Lee, Kil Sun [UNIFESP]; Pino, Jessica Monteiro Volejnik [UNIFESP]; http://lattes.cnpq.br/7067036778917817; http://lattes.cnpq.br/7705881286363327; http://lattes.cnpq.br/0719868888434932
    Introdução: O fígado é um órgão fundamental no desempenho de diversas funções vitais, incluindo o metabolismo de macronutrientes. A disfunção desse órgão pode gerar uma das hepatopatias mais alarmantes nos últimos anos, a Doença Hepática Gordurosa não Alcoólica (DHGNA). Amplo espectro histológico de lesão hepática, iniciando com esteatose hepática (EH) que está cada vez mais associada à síndrome metabólica (SM) na obesidade, para a qual, a cirurgia bariátrica é considerada um dos principais tratamentos. Objetivo: Investigar como a esteatose hepática afeta a composição corporal, o desempenho cognitivo e a resposta à cirurgia bariátrica. Métodos: Voluntárias realizaram coleta de sangue, exame de bioimpedância e uma bateria de testes cognitivos. Os parâmetros bioquímicos foram obtidos dos prontuários eletrônicos. Os metabólitos circulantes foram analisados por CG/EM usando amostras de plasma. Estratificação pelo grau de esteatose hepática (grupo 1: ausente e leve; grupo 2: moderado e grave) Resultados: Maior grau de EH apresentou maiores níveis de glicemia (p=0,012), insulina (p=0,001) e Homa-IR (p=0,001) antes da cirurgia. Foi observado um menor efeito da cirurgia sobre o ganho de massa muscular (p=0,009) e perda de gordura corporal (p=0,0013) no grupo com maior grau de EH. No teste cognitivo, observou-se melhora nos testes de atenção em ambos os grupos após a cirurgia. O perfil metabólico mostrou que os macronutrientes são as principais classes de moléculas que se alteraram entre os grupos. Discussão: De acordo com a literatura, a EH pode ser causa ou consequência da resistência insulínica. A homeostase muscular depende do equilíbrio de várias vias metabólicas, que é regulada pela insulina. Portanto, nossa observação pode ser explicada pela resistência insulínica presente antes da cirurgia, que também pode alterar o perfil dos metabólitos circulantes. Conclusão: Um maior grau de esteatose hepática parece estar associado à resistência insulínica, o que pode atenuar o efeito da cirurgia bariátrica. A investigação dessa relação é importante, pois tal relação pode colaborar para uma diminuição da qualidade de vida dos indivíduos portadores de EH.
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    Avaliação da massa muscular medida pela tomografia computadorizada abdominal como preditor de morbidade e mortalidade em pacientes na fase não dialítica da doença renal crônica
    (Universidade Federal de São Paulo (UNIFESP), 2019-05-30) Bichels, Andre Valente [UNIFESP]; Kaneko, Maria Ayako Kamimura [UNIFESP]; Silva Júnior, Antonio Carlos Cordeiro; http://lattes.cnpq.br/5874601346158886; http://lattes.cnpq.br/3356377676492451; http://lattes.cnpq.br/7254976533483796; Universidade Federal de São Paulo (UNIFESP)
    Background: In chronic kidney disease (CKD), multiple metabolic and nutritional abnormalities contribute to the loss of skeletal muscle mass. Muscle mass is a key element for evaluation of nutritional disturbances, and low muscle mass is associated with increased morbidity and mortality. An accurate method for muscle mass evaluation that is not subject to errors caused by perturbations in the uremic milieu remains a challenge for the nephrology community. Methods: This is a prospective observational cohort study. We evaluated 223 non-dialyzed CKD patients [60.3±10.6 years; 64% men; 50% diabetics; glomerular filtration rate (GFR) 27.3±16.3 ml/min/1.73m2]. Muscle mass was measured by computed tomography at the third lumbar vertebra region (CTMM-L3) using the Slice-O-Matic software and analyzed according to percentile adjusted by gender. Nutritional parameters, laboratory data and comorbidities were evaluated, and mortality was followed-up for 4 years. Results: During the study period 63 patients died, and the main cause of death was cardiovascular disease. Patients who died were older, had lower GFR, hemoglobin and albumin, as well as lower muscle markers. CTMM-L3 below the 25th percentile was associated with higher mortality according to the Kaplan-Meier curve (P=0.017), and in Cox-regression analysis [crude hazard ratio, HR, 1.87 (95% confidence interval, CI, 1.11-3.16)], also when adjusting for potential confounders [HR 1.83 (CI 1.02-3.30)]. Conclusions: Low muscle mass measured by computed tomography at the third lumbar vertebra region is an independent predictor of increased mortality in non-dialyzed CKD patients.
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    Avaliação das concentrações de vitamina D em pacientes com imunodeficiência comum variável e ataxia-telangiectasia
    (Universidade Federal de São Paulo (UNIFESP), 2018-05-25) Cruz, Julia Rosental de Souza [UNIFESP]; Sarni, Roseli Oselka Saccardo [UNIFESP]; http://lattes.cnpq.br/1760819469047929; http://lattes.cnpq.br/8769460841656743; Universidade Federal de São Paulo (UNIFESP)
    Introduction: 1.25 hydroxyvitamin D plays many roles in the body, including the immune system modulation. The Primary Immunodeficiencies (PID) are a group of diseases which affect B and T cells, compromising the humoral and adaptive immunity. Objectives: To assess vitamin D status in AT and CVID patients and, to correlate vitamin D status to: body composition, inflammatory markers and markers of bone metabolism. Methods: Crosssectional, observational and controlled study, involving 15 CVID patients, nine AT patients and 24 healthy controls, paired by sex and age. Were assessed: 25(OH) D – Hydroxyvitamin D, lipid profile, markers of liver function, Creactive protein, parathyroid hormone, alkaline phosphatase, interleukin 6, insulin, phosphorus, calcium, and blood sugar levels. Anthropometric evaluation was also performed. Results: Mean age of 26.0 years. Vitamin D deficiency was found in four AT patients (44%) and two CVID patients (13%). 60% of the CVID patients were overweight. Six (66,7%) AT patients were underweight. A negative correlation between vitamin D and fat mass was found in CVID patients (ρ = 0.5580 e p = 0.306) and a negative correlation between Body Mass Index and vitamin D in AT (ρ = 0,6788 e p = 0,0444). Conclusion: Vitamin D deficiency was found only in the patients group. No correlation with blood markers was found. It was found a negative correlation between vitamin D and body composition.
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    Basal Metabolic Rate and Body Composition in Patients with Post-Polio Syndrome
    (Karger, 2008-01-01) Bargieri, J. V.; Quadros, A. A. J.; Pereira, R. D. B.; Oliveira, A. J. B.; Lazaretti-Castro, M.; Silva, A. C.; Universidade Federal de São Paulo (UNIFESP)
    The aim of this study was to compare basal metabolic rate (BMR) of post-polio syndrome ( PPS) patients with healthy individuals and to determine its correlation to body composition. BMR (kcal/day) was determined by indirect calorimetry and body composition by dual energy X-ray absorptiometry. BMR was lower in the PPS patient group than in the control group, although it was similar in both groups when adjusted for body surface area, total body mass (TBM), lean body mass (LBM) and fat-free mass (FFM). PPS patients also showed reduced TBM, LBM and FFM in relation to controls. As muscle energy expenditure while at rest contributes only 20% to the BMR, a proportional reduction in BMR and FFM or LBM could suggest that muscle mass or other factors may interfere more than predicted. It was concluded that the prediction of BMR from the Harris-Benedict equation in PPS patients must be carefully reviewed. Copyright (C) 2008 S. Karger AG, Basel
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    Bioelectric impedance overestimates the body fat in overweight and underestimates in Brazilian obese women: a comparation with Segal equation 1
    (Aula Medica Ediciones, 2010-09-01) Pimentel, Gustavo Duarte [UNIFESP]; Bernhard, A. B.; Frezza, M. R. P.; Rinaldi, A. E. M.; Burini, R. C.; Universidade Federal de São Paulo (UNIFESP); Universidade de São Paulo (USP); Universidade Federal de Uberlândia (UFU)
    Introduction: Overweight and obesity are risk factors to appearance of cardiovascular diseases and anthropometry is important as clinical tool for planning and health policymaking at population level. Thus, aim of this work was to compare the simple body fat percentage (%BF) obtained straight by bioeletric impedance (BIA) to the one obtained by the equation of Segal et al (1988), which uses the BIA resistance value, overweight among adult women.Methods: This study conducted with 86 adult women (50.5 +/- 11.0 years old). Body weight and height were measured and estimated the body mass index (BIND. %BF was assessed by BIA (Biodynamics (R) model 450) and Segal equation.Results: %BF derived from BIA (38.0 +/- 4.6%) and Segal et al (1988) (38.7 +/- 8.1%) were similar (p = 0.85). However, when the women were distributed, in two groups based on their BMI, overweight (n = 40; BMI = 27.3 +/- 1.2 kg/m(2)) and obesity (n = 46; BMI = 36.2 +/- 5.1 kg/m(2)), the two methods presented results significant different (p = 0.000). the %BF of overweight women was 34.6 +/- 3.6% by BIA and 30.3 +/- 2.1% when estimated by Segal equation. in obese women, the %BF was 41.0 +/- 3.0% and 46.0 +/- 2.6%, respectively.Conclusion: BIA overestimated %BF in overweight (+14.2%; +3.0 kg) and underestimated in obese (-10.9%; -4.4 kg) women.
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    Body composition analysis by DXA (dual X-ray absorptiometry) in Brazilian men: normative data
    (Springer Japan Kk, 2017) Ushida, Marcela [UNIFESP]; Pinheiro, Marcelo de Medeiros [UNIFESP]; de Moura Castro, Charlles Heldan [UNIFESP]; Szejnfeld, Vera Lucia [UNIFESP]
    Considering ethnic and anthropometric differences, it is important to obtain specific normative data on body composition (BC) for each population. The objectives of this study were to obtain the normative curve for the BC of Brazilian men and to compare them to the North American male population. A total of 403 healthy Brazilian men 20 years and older were included in the study. Data on concomitant diseases and physical activity were investigated using a structured questionnaire. Conditions that could affect lean and fat mass were excluded. BC was assessed via whole-body dual-energy X-ray absorptiometry (DXA) using a GE-Lunar device. Significance level was set as p < 0.05. Mean age and body mass index (BMI) were 46.0 +/- 17.9 years and 26.2 +/- 3.14 kg/m(2), respectively. Mean skeletal mass index (SMI), appendicular lean mass by BMI (ALM(BMI)), and fat mass index (FMI) were 8.38 +/- 0.85, 0.949 +/- 0.138, and 6.87 +/- 2.43 kg/m(2), respectively. There were negative associations among SMI (p < 0.001), ALM(BMI) (p < 0.001), and FMI (p = 0.002) with age. Comparison with the National Health and Nutrition Examination Survey (NHANES) III data, originally performed with a Hologic device, showed that Brazilian men had lower FMI and BF. This difference was minimized after converting the NHANES results to the GE-Lunar database. Brazilian men had lower SMI than American men measured in NHANES III. FMI was less influenced by ethnicity than by BMI, and it could be used as a standard measure for assessing fat excess or adiposity. Our data suggest that conversion to each specific manufacturer's database should be performed to minimize differences in body composition between populations.
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    Body composition and lipodystrophy in prepubertal HIV-infected children
    (Brazilian Society of Infectious Diseases, 2013-02-01) Palchetti, Cecília Zanin [UNIFESP]; Patin, Rose Vega [UNIFESP]; Gouvêa, Aida de Fátima Thomé Barbosa [UNIFESP]; Szejnfeld, Vera Lucia [UNIFESP]; Succi, Regina Célia de Menezes [UNIFESP]; Oliveira, Fernanda Luisa Ceragioli [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    OBJECTIVE: To identify lipodystrophy in prepubertal HIV-infected children using anthropometric parameters and body composition assessment. METHODS: Cross-sectional study including 40 prepubertal HIV-infected children of both genders seen at the Care Center of the Division of Pediatric Infectious Diseases - Universidade Federal de São Paulo (UNIFESP), São Paulo city, Brazil, was carried out from August to December 2008. Age, clinical and immunological status, prophylaxis, transmission and highly active antiretroviral therapy were recorded. Body mass index z-score and height-for-age z-score were calculated to characterize the nutritional status. Circumferences were measured with flexible tape and skinfolds were assessed by an adipometry. Fat mass and lean mass were determined by dual-energy X-ray absorptiometry. Presence of clinical signs of lipodystrophy was assessed by a trained clinician. Data were analyzed using SPSS 12.0 software. RESULTS: The mean age and standard deviation were 9.8 (1.2) years, 50% were girls and 82.5% children from B and C categories. Clinical lipodystrophy and dislypidemia were present in 27.5% and 70%, respectively. The trunk to arm ratio and the limb to trunk ratio had positive association with lipodystrophy. Patients with lipodystrophy had short stature, higher triglycerides values and lower HDL-cholesterol. CONCLUSION: The ratios obtained by skinfolds and dual-energy X-ray absorptiometry measurements can be considered as indicators of preclinical lipodystrophy. The cutoff points have not been determined yet; however, continuous assessment may be useful to identify early body composition changes.
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    Body composition in patients with classical homocystinuria: body mass relates to homocysteine and choline metabolism
    (Elsevier B.V., 2014-08-10) Poloni, Soraia; Leistner-Segal, Sandra; Bandeira, Isabel Cristina; D'Almeida, Vânia [UNIFESP]; Souza, Carolina Fischinger Moura de; Spritzer, Poli Mara; Castro, Kamila; Tonon, Tássia; Nalin, Tatiele; Imbard, Apolline; Blom, Henk J.; Schwartz, Ida Vanessa Doederlein; Univ Fed Rio Grande do Sul; Hosp Clin Porto Alegre; Universidade Federal de São Paulo (UNIFESP); Robert Debre Hosp; Univ Med Ctr Freiburg
    Introduction: Classical homocystinuria is a rare genetic disease caused by cystathionine beta-synthase deficiency, resulting in homocysteine accumulation. Growing evidence suggests that reduced fat mass in patients with classical homocystinuria may be associated with alterations in choline and homocysteine pathways. This study aimed to evaluate the body composition of patients with classical homocystinuria, identifying changes in body fat percentage and correlating findings with biochemical markers of homocysteine and choline pathways, lipoprotein levels and bone mineral density (BMD) T-scores.Methods: Nine patients with classical homocystinuria were included in the study. Levels of homocysteine, methionine, cysteine, choline, betaine, dimethylglycine and ethanolamine were determined. Body composition was assessed by bioelectrical impedance analysis (BIA) in patients and in 18 controls. Data on the last BMD measurement and lipoprotein profile were obtained from medical records.Results: of 9 patients, 4 (44%) had a low body fat percentage, but no statistically significant differences were found between patients and controls. Homocysteine and methionine levels were negatively correlated with body mass index (BMI), while cysteine showed a positive correlation with BMI (p < 0.05). There was a trend between total choline levels and body fat percentage (r = 0.439, p = 0.07). HDL cholesterol correlated with choline and ethanolamine levels (r = 0.757, p = 0.049; r = 0.847, p = 0.016, respectively), and total cholesterol also correlated with choline levels (r = 0.775, p = 0.041). There was no association between BMD T-scores and body composition.Conclusions: These results suggest that reduced fat mass is common in patients with classical homocystinuria, and that alterations in homocysteine and choline pathways affect body mass and lipid metabolism. (C) 2014 Elsevier B.V. All rights reserved.