Navegando por Palavras-chave "periodic leg movements"
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- ItemSomente MetadadadosCorrelation between K complex, periodic leg movements (PLM), and myoclonus during sleep in paraplegic adults before and after an acute physical activity(Stockton Press, 1997-04-01) Mello, Marco Tulio de [UNIFESP]; Silva, Antônio Carlos [UNIFESP]; Rueda, A. D.; Poyares, Dalva [UNIFESP]; Tufik, Sergio [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)K complex is the characteristic wave of stage II of sleep. the relationship between periodic limb movements (PLM) and the restless legs syndrome (RLS), and the incidence of K complexes and alpha activity has been previously described. the aim of the present study was to evaluate the effect of an acute physical activity upon K complex, PLM, and myoclonus during sleep in individuals who were paraplegic. We evaluated 84 polysomnograms from 28 volunteers with a spinal cord injury at the level of T7-T12, obtained during three consecutive nights. On day 3, the volunteers were submitted to a test of maximum effort (manual cycloergometer, with the equipment Cybex Met 300, with a progressive load increase of 12.5 w, every 2 min). the analysis of the polysomnographic recordings showed a positive correlation between the incidence of K complex and limb movements on nights 1, 2 and 3. Similarly, a correlation between the incidence of K complex and myoclonus was observed on nights 1, 2 and 3. An increased incidence of the total K complex was seen on night 3, 36 h after the test of maximum effort. Both total K complex and K complex/h were reduced on night 2, compared to basal recording (night 1). There was a reduction of sleep latency on night 2, whereas total sleeping time increased progressively on night 3, as well as REM phase on nights 2 and 3. These findings indicate that physical activity can affect or modulate the incidence of K complex and suggest that a positive correlation between PLM and K complex may occur in those who are paraplegic from a spinal cord injury. in conclusion, sleep can be consolidated after physical activity.
- ItemSomente MetadadadosEstrogen therapy reduces nocturnal periodic limb movements(Elsevier B.V., 2007-11-20) Hachul, Helena; Baracat, Edmund Chada [UNIFESP]; Soares, Jose Maria [UNIFESP]; Haidar, Mauro Abi [UNIFESP]; Mello, Marco Tulio de [UNIFESP]; Tufik, Sergio [UNIFESP]; Bittencourt, Lia Rita Azeredo [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)It is believed that periodic lirnb movement (PLM) and more specifically, restless leg syndrome (RLS), are a common cause of insomnia. and one study in the literature examined PLM when associated to the use of estrogens. Polo-Kantola et al. [Polo-Kantola P, Rauhala E, Erkkola R, Irjala K, Polo O. Estrogen replacement therapy and nocturnal periodic limb movements: a randomized controlled trial. Obstet Gynecol 2001;97(4):548-54] observed that estrogen therapy improved subjective sleep quality regardless of periodic limb movements or related arousals. Herein is a case of a symptomatic postmenopausal patient with high PLM index who complained of insomnia and leg pain. Given that the patient had hot flashes and a high Kupperman Menopausal Index (which evaluates climacteric symptoms), we decided to administer transdermal ESTRADOT 25 mu g (Novartis, Brazil) twice-a-week. Our patient experienced a significant decrease in PLM as well as a great increase in REM and a slight increase in slow wave sleep (stages 3 and 4), as shown in the polysomnography. the patient reported an overall improvement in her condition. (C) 2007 Elsevier Ireland Ltd. All rights reserved.
- ItemSomente MetadadadosSíndrome das pernas inquietas: diagnóstico e tratamento. Opinião de especialistas brasileiros(Assoc Arquivos Neuro- Psiquiatria, 2007-09-01) Aloe, Flávio; Alves, Rosana S Cardoso; Andrade, Luiz Augusto Franco [UNIFESP]; Assis,Márcia; Bacelar, Andrea; Bezerra, Márcio; Cardoso, Francisco [UNIFESP]; Ferraz, Henrique Ballalai [UNIFESP]; Fonseca, Ronaldo Guimarães; Horta, Wagner; Haddad, Mônica Santoro; Hasan, Rosa; Mattos, James Pitágoras; Prado, Gilmar Fernandes do [UNIFESP]; Rizzo, Geraldo; Rodrigues, Nonato; Silva, Ademir Batista da [UNIFESP]; Silva, Delson Jose; Teive, Helio Afonso Ghizoni; Grupo Brasileiro de Estudos em Síndrome das Pernas Inquietas (GBE-SPI); Universidade de São Paulo (USP); Hosp Israelita Albert Einstein; Pratica privada; Practica Privada; Universidade Federal de Minas Gerais (UFMG); Universidade Federal de São Paulo (UNIFESP); UFCE; Universidade Federal de Goiás (UFG)This article contains the conclusions of the November 17-18, 2006 meeting of the Brazilian Study Group of Restless Legs Syndrome (GBE-SPI) about diagnosis and management of restless legs syndrome (RLS). RLS is characterized by abnormal sensations mostly but not exclusively in the legs which worsen in the evening and are improved by motion of the affected body part. its diagnosis is solely based on clinical findings. Therapeutic agents with efficacy supported by Class I studies are dopamine agonists, levodopa and gabapentine. Class 11 studies support the use of slow release valproic acid, clonazepan and oxycoclone. The GBE-SPI recommendations for management of SPI are sleep hygiene, withdrawal of medications capable of worsening the condition, treatment of comorbidities and pharmacological agents. The first choice agents are dopaminergic drugs, second choice are gabapentine or oxycodone, and the third choice are clonazepan or slow release valproic acid.
- ItemSomente MetadadadosTwo pedigrees with restless legs syndrome in Brazil(Assoc Bras Divulg Cientifica, 2008-02-01) Esteves, Andrea Maculano [UNIFESP]; Pedrazzoli, Mario [UNIFESP]; Bagnato, Maurício da Cunha [UNIFESP]; Moreira, F. [UNIFESP]; Mello, Marco Tulio de [UNIFESP]; Tufik, Sergio [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Numerous studies have suggested a substantial genetic contribution in the etiology of the primary form of restless legs syndrome (RLS) and periodic leg movements (PLM). We describe the symptoms, the sleep profiles and physiological parameters of two families in which several members present RLS/PLM. The proband of family 1 is a 70-year-old woman and the proband of family 2 is a 57-year-old woman; both have exhibited the symptoms since the age of 20 years. All patients in both families were diagnosed with RLS according to the criteria of the International RLS Study Group. Polysomnographic recordings were performed to quantify and to describe PLM during sleep. Sleep parameters showed decreased sleep efficiency, increased sleep latency in the arousal index and the presence of PLM in all subjects. One of the families showed an exact profile of dominant inheritance with anticipation of age at onset. In the other family, the founders were blood relatives and there was no affected member in the third generation suggesting a recessive mode of inheritance. RLS/PLM is a prevalent sleep disorder affecting about 5 to 15% of the population and one that substantially impairs healthy sleep patterns. Efforts to understand the underlying pathophysiology will contribute to improve the sleep and life quality of these patients.