Navegando por Palavras-chave "cerebrovascular disease"

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    Detection of Cerebral Vasculopathy by Transcranial Doppler in Children With Neurofibromatosis Type 1
    (Sage Publications Inc, 2016) Sagica Fernandes Paschoal, Joelma Karin [UNIFESP]; Paschoal, Fernando Mendes, Jr.; de Lima, Fernanda Teresa [UNIFESP]; Pinho, Ricardo Silva [UNIFESP]; Pereira Vilanova, Luiz Celso [UNIFESP]; Bor-Seng-Shu, Edson; Masruha, Marcelo Rodrigues [UNIFESP]
    Neurofibromatosis type 1 is characterized by nerve sheath neurofibromas associated with a number of additional clinical features, including cerebrovascular disease. The aim of this study was to use transcranial Doppler as a screening method for identifying cerebral vasculopathy in children with neurofibromatosis type 1. Forty children with neurofibromatosis type 1, aged 5 to 18 years old, were examined by transcranial Doppler. Patients presenting with hemodynamic features of arterial stenosis/occlusion on transcranial Doppler underwent magnetic resonance angiography to confirm the findings. Magnetic resonance angiography was performed on 4 children who exhibited a transcranial Doppler hemodynamic pattern indicative of cerebral vasculopathy. Among these cases, 2 presented internal carotid artery stenosis/occlusion, 1 had bilateral middle cerebral artery stenosis, and 1 presented a normal magnetic resonance angiography result. Transcranial Doppler can be used routinely in the investigation of cerebrovascular disease in neurofibromatosis type 1 patients, where magnetic resonance angiography can be subsequently applied to confirm the diagnosis, further contributing to the prevention of cerebrovascular events.
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    Fibrinogênio como fator de risco independente de doença vascular cerebral
    (Academia Brasileira de Neurologia - ABNEURO, 1997-01-01) Fukujima, Marcia Maiumi [UNIFESP]; Martinez, Tânia Leme da Rocha [UNIFESP]; Pinto, Leonor do Espírito Santo de Almeida [UNIFESP]; Auriemo, Caio R.c. [UNIFESP]; Andrade, Luiz Augusto Franco de [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    We have studied fibrinogen levels (Clauss technique) in atherothrombotic ischemic stroke patients, in order to determine its role as a thombogenic risk factor. Twenty nine patients (20 men and 9 women) between 25 and 79 years old were studied; they all have had a atherothrombotic stroke. They were classified into two groups according to the result of their carotid doppler ultrasonography: g1 - without carotid flow reduction (n=l 9) and g2 - with carotid flow reduction (n=10). The fibrinogen mean value was 269mg/dl in gl and 353 mg/dl in g2. There were 47% of patients in gl and 80% of patients in g2 who presented levels >300 mg/dl. The proportions of the groups were significantly different (p<0,05). Considering the epidemiological value of 300 mg/dl, we conclude that the fibrinogen can be an independent risk factor for ischemic atherothrombotic stroke, specially in those whose carotid flow is reduced.