Navegando por Palavras-chave "Skin diseases, metabolic"

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    Xantogranuloma necrobiótico solitário sem paraproteinemia
    (Sociedade Brasileira de Dermatologia, 2008-06-01) Macedo, Danielle Mazziero [UNIFESP]; Hirata, Sergio Henrique [UNIFESP]; Michalany, Nilceo Schwery [UNIFESP]; Enokihara, Mílvia Maria Simões e Silva [UNIFESP]; Enokihara, Silva [UNIFESP]; Enokihara, Mauro Yoshiaki [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)
    Necrobiotic xanthogranuloma is a chronic granulomatous and xantomathous disease, characterized by indurated, nontender, yellowish and erythematous nodules and plaques especially located on the periorbital region. It is commonly associated with paraproteinemia and an increased risk for hematological and lymphoproliferative malignancies. Its pathogenesis remains unclear. Alkylating agents, such as chlorambucil and melphalan may be used to treat the disease with variable success. We report a case of this rare disease in a patient with a solitary tumor and without paraproteinemia.