Navegando por Palavras-chave "Respiratory tract infection"
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- ItemAcesso aberto (Open Access)Bronquiolite aguda, uma revisão atualizada(Associação Médica Brasileira, 2007-04-01) Carvalho, Werther Brunow de [UNIFESP]; Johnston, Cíntia [UNIFESP]; Fonseca, Marcelo Cunio Machado [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Acute bronchiolitis (AB) is a frequent cause of hospitalization among children and its main etiological agent is respiratory syncytial virus (RSV). It occurs epidemically during autumn and winter. Some populations of children such as premature newborns, infants with congenital heart disease and those with chronic lung disease, immunocompromised, undernourished, among others, present increased morbidity and mortality risk. The virus multiplies in epithelial ciliated cells while inflammation and cellular debris cause obstruction of the airways, hyperinflation, atelectasis, and wheezing and gas exchange imbalance. Definitive evidence still does not exist about treatment of this disease, Treatment includes oxygen therapy, hydration, inhaled beta-2 agonists, racemic epinephrine, recombinant DNase and respirotherapy, among others. Prophylactic measures include administration of monoclonal antibodies. The majority of children with AB, independent of disease severity, recover without sequels. The natural course of this disease usually varies, from seven to ten days ,however some children may not recover for weeks.
- ItemSomente MetadadadosHuman coronavirus NL-63 infection in a Brazilian patient suspected of H1N1 2009 influenza infection: Description of a fatal case(Elsevier B.V., 2012-01-01) Cabeca, Tatiane K. [UNIFESP]; Bellei, Nancy [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)Human coronaviruses (HCoVs) cause upper respiratory tract and occasionally lower respiratory tract diseases. the recently described human coronavirus NL63 has not been well investigated among Brazilian patients. We reported the clinical course of an HCoV-NL63 infection in a hospitalised patient suspected of H1N1 2009 infection during the second pandemic wave of influenza activity. A 46-year-old female, health care worker with diabetes and presenting with influenza-like illness (ILI) was admitted to the hospital. During 9 days of influenza-like symptoms, the patient had diabetes decompensation, haemorrhagic pneumonia, rhabdomyolysis, respiratory and renal failure, pericarditis, and brain edema and died. HCoV-NL63 may be a causative agent of previously unexplained respiratory illnesses. Crown Copyright (C) 2011 Published by Elsevier B. V. All rights reserved.