Navegando por Palavras-chave "Muscle tissue"
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- ItemSomente MetadadadosComparative study of the effects of low-intensity pulsed ultra-sound and low level laser therapy on injured muscle repair(Spie-int Soc Optical Engineering, 2011-01-01) Renno, Ana Claudia Muniz [UNIFESP]; Toma, Renata Luri [UNIFESP]; Feitosa, Suellen Maurin [UNIFESP]; Fernandes, Kelly Rossetti [UNIFESP]; Oliveira, Poliani de [UNIFESP]; Parizotto, Nivaldo Antonio [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP]; Hamblin, Michael R.; Waynant, R. W.; Anders, J.; Universidade Federal de São Paulo (UNIFESP)Muscle tissue is one of the most frequently affected by injury, whether during sports activities, or work activities. in this context, biochemical and biophysical resources have been studied to minimize the time of muscle regeneration. Among these, low intensity pulsed ultrasound (US) and low level laser therapy (LLLT) may be highlighted. Despite a series of evidences about the positive effects of these resources in the process of tissue regeneration, the cellular and morphological changes triggered by LLLT and U. S. are still largely unknown. Thus, the aim of this study was to investigate the effects of US and LLLT on muscle repair after cryolesion by means of histopathological analysis and immunohistochemistry for COX-2. A total of thirty five male Wistar rats were randomly distributed into 4 groups: intact control group; injured control group: muscle injured animals without any treatment; laser treated group: muscle injured animals treated with 830 nm laser and ultra-sound treated group: muscle injured animals treated with US. the treatments started 24 hours post-surgery and were performed during 6 sessions. the animals exposed to lasertherapy pointed out minor degenerative changes of muscle tissue. in the same way, exposure to ultrasound was able to reduce tissue injuries induced by cryolesion, but less intense than laser therapy. Strong COX-2 positive cells were found in rats submitted to cryolesion only, whereas COX-2 immunoexpression was lower in laser treated or ultrasound treated groups. in summary, this study reveals that both lasertherapy and ultrasound have positive effects on muscle repair in rats.
- ItemSomente MetadadadosEffects of 660 nm low-level laser therapy on muscle healing process after cryolesion(Journal Rehab Res & Dev, 2013-01-01) Rodrigues, Natalia Camargo; Assis, Livia [UNIFESP]; Fernandes, Kelly Rossetti [UNIFESP]; Magri, Angela Maria Paiva [UNIFESP]; Ribeiro, Daniel Araki [UNIFESP]; Brunelli, Roberta de Matos; Abreu, Daniela Cristina Carvalho de; Renno, Ana Claudia Muniz [UNIFESP]; Universidade Federal de São Carlos (UFSCar); Universidade Federal de São Paulo (UNIFESP); Universidade Estadual de Campinas (UNICAMP); Universidade de São Paulo (USP)The aim of this study was to evaluate the effects of 660 nm low-level laser therapy (LLLT) on muscle regeneration after cryolesion in rat tibialis anterior muscle. Sixty-three Wistar rats were divided into a control group, 10 J/cm(2) laser-treated group, and 50 J/cm2 laser-treated group. Each group formed three subgroups (n = 7 per group), and the animals were sacrificed 7, 14, or 21 d after lesion. Histopathological findings revealed a lower inflammatory process in the laser-treated groups after 7 d. After 14 d, irradiated animals at both fluences showed higher granulation tissue, new muscle fibers, and organized muscle structure. After 21 d, full tissue repair was observed in all groups. Moreover, irradiated animals at both fluences showed smaller necrosis area in the first experimental period evaluated. MyoD immunoexpression was observed in both treated groups 7 d postinjury. Myogenin immunoexpression was detected after 7 and 14 d. the higher fluence increased the number of blood vessels after 14 and 21 d. These results suggest that LLLT, at both fluences, positively affects injured skeletal muscle in rats, accelerating the muscle-regeneration process.
- ItemSomente MetadadadosPotencial preventivo do extrato de Bauhinia Forficata link, rico em canferol, e da Canferitrina sobre o metabolismo glicêmico após desafio com dieta hipercalórica e hiperlipídica.(Universidade Federal de São Paulo (UNIFESP), 2018-12-17) Garofolo, Ingrid Candido [UNIFESP]; Caperuto, Luciana Chagas [UNIFESP]; Universidade Federal de São Paulo (UNIFESP)According To The International Diabetes Federation, In 2015, 5 Million People Died Due To Complications Of Diabetes. Type 2 Diabetes Mellitus (Dm2) Is Characterized By Hyperglycemia And Hyperinsulinemia, As Well As Changes In The Metabolism Of Lipids, Carbohydrates And Proteins. In This Context, New Alternatives, Including Plant Extracts Containing Bioactive Substances, Such As Flavonoids, Are Under Experimental And Clinical Investigation In Order To Prevent The Progress Of Metabolic Disorders Or Even Prevent The Development Of These Disorders. The Neotropical Specie Bauhinia Forficata Link (Bf) Is A Tree Whose Leaves Are Widely Used In Folk Medicine As Anti-Diabetogenic. The Characteristic Action Is Hypoglycemic, Which Is Due To The Presence Of Flavonoids. Among Them, It Highlights The Kaempferol-3,7-O-(")-Dirhamnoside (Kaempferitrin). Therefore, The Main Goal Of The Present Study Was To Evaluate The Glycemic Metabolism Of C57bl/6j Mice, Challenged With High-Fat Diet /High-Sucrose (Hfhs) And Treated With Kae